Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells

Toxicology and Applied Pharmacology

Volumn 213, Issue 2, 2006, Pages 98-104

  Chan, Nelson L S ^a   Wang, Huan ^a   Wang, Yun ^a   Leung, Hau Yi ^a   Leung, Lai K ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

CYP1A1; CYP1B1; DMBA; Limonene; Perillyl alcohol; XRE

Indexed keywords

CARCINOGEN; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DIMETHYLBENZ[A]ANTHRACENE; ETHOXYRESORUFIN DEETHYLASE; LUCIFERASE; MESSENGER RNA; PERILLYL ALCOHOL; POLYCYCLIC AROMATIC HYDROCARBON; TERPENE; XENOBIOTIC AGENT;

ARTICLE; BIOTRANSFORMATION; CANCER RISK; CELL STRAIN MCF 7; DNA BINDING; DRUG EFFECT; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; ENZYME REPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; XENOBIOTIC METABOLISM;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANTINEOPLASTIC AGENTS; ARYL HYDROCARBON HYDROXYLASES; BREAST NEOPLASMS; CARCINOGENS; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; DNA ADDUCTS; DNA DAMAGE; DOWN-REGULATION; DRUG INTERACTIONS; ENZYME INHIBITORS; EPITHELIAL CELLS; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MONOTERPENES; POLYCYCLIC HYDROCARBONS, AROMATIC; TRANS-ACTIVATION (GENETICS); XENOBIOTICS;

EID: 33646740154     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.10.002     Document Type: Article

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