-
1
-
-
77953584054
-
Creation of a bacterial cell controlled by a chemically synthesized genome
-
doi: science.1190719
-
Gibson D.G., Glass J.I., Lartigue C., Noskov V.N., Chuang R.-Y., Algire M.A., Benders G.A., Montague M.G., Ma L., Moodie M.M., et al. Creation of a bacterial cell controlled by a chemically synthesized genome. Science 2010, doi: science.1190719.
-
(2010)
Science
-
-
Gibson, D.G.1
Glass, J.I.2
Lartigue, C.3
Noskov, V.N.4
Chuang, R.-Y.5
Algire, M.A.6
Benders, G.A.7
Montague, M.G.8
Ma, L.9
Moodie, M.M.10
-
3
-
-
66749182798
-
13C-based metabolic flux analysis
-
Zamboni N., Fendt S.-M., Ruhl M., Sauer U. 13C-based metabolic flux analysis. Nat Protoc 2009, 4:878-892.
-
(2009)
Nat Protoc
, vol.4
, pp. 878-892
-
-
Zamboni, N.1
Fendt, S.-M.2
Ruhl, M.3
Sauer, U.4
-
4
-
-
77953329895
-
Prediction of novel synthetic pathways for the production of desired chemicals
-
Cho A., Yun H., Park J., Lee S., Park S. Prediction of novel synthetic pathways for the production of desired chemicals. BMC Syst Biol 2010, 4:35.
-
(2010)
BMC Syst Biol
, vol.4
, pp. 35
-
-
Cho, A.1
Yun, H.2
Park, J.3
Lee, S.4
Park, S.5
-
5
-
-
53049109464
-
De novo biosynthetic pathways: rational design of microbial chemical factories
-
Prather K.L.J., Martin C.H. De novo biosynthetic pathways: rational design of microbial chemical factories. Curr Opin Biotechnol 2008, 19:468-474.
-
(2008)
Curr Opin Biotechnol
, vol.19
, pp. 468-474
-
-
Prather, K.L.J.1
Martin, C.H.2
-
6
-
-
77954188312
-
Finding metabolic pathways using atom tracking
-
Heath A.P., Bennett G.N., Kavraki L.E. Finding metabolic pathways using atom tracking. Bioinformatics 2010, 26:1548-1555.
-
(2010)
Bioinformatics
, vol.26
, pp. 1548-1555
-
-
Heath, A.P.1
Bennett, G.N.2
Kavraki, L.E.3
-
7
-
-
17444382016
-
Exploring the diversity of complex metabolic networks
-
Hatzimanikatis V., Li C., Ionita J.A., Henry C.S., Jankowski M.D., Broadbelt L.J. Exploring the diversity of complex metabolic networks. Bioinformatics 2005, 21:1603-1609.
-
(2005)
Bioinformatics
, vol.21
, pp. 1603-1609
-
-
Hatzimanikatis, V.1
Li, C.2
Ionita, J.A.3
Henry, C.S.4
Jankowski, M.D.5
Broadbelt, L.J.6
-
8
-
-
77952717854
-
Design and analysis of synthetic carbon fixation pathways
-
Bar-Even A., Noor E., Lewis N.E., Milo R. Design and analysis of synthetic carbon fixation pathways. Proc Natl Acad Sci USA 2010, 107:8889-8894.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8889-8894
-
-
Bar-Even, A.1
Noor, E.2
Lewis, N.E.3
Milo, R.4
-
9
-
-
77951125481
-
Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity
-
Fendt S.-M., Buescher J.M., Rudroff F., Picotti P., Zamboni N., Sauer U. Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity. Mol Syst Biol 2010, 6.
-
(2010)
Mol Syst Biol
, pp. 6
-
-
Fendt, S.-M.1
Buescher, J.M.2
Rudroff, F.3
Picotti, P.4
Zamboni, N.5
Sauer, U.6
-
10
-
-
42949164125
-
Formulating genome-scale kinetic models in the post-genome era
-
Jamshidi N., Palsson B.O. Formulating genome-scale kinetic models in the post-genome era. Mol Syst Biol 2008, 4:171.
-
(2008)
Mol Syst Biol
, vol.4
, pp. 171
-
-
Jamshidi, N.1
Palsson, B.O.2
-
11
-
-
77952797285
-
Streamlining the construction of large-scale dynamic models using generic kinetic equations
-
Adiamah D.A., Handl J., Schwartz J.-M. Streamlining the construction of large-scale dynamic models using generic kinetic equations. Bioinformatics 2010, 26:1324-1331.
-
(2010)
Bioinformatics
, vol.26
, pp. 1324-1331
-
-
Adiamah, D.A.1
Handl, J.2
Schwartz, J.-M.3
-
12
-
-
52949144952
-
Top-down analysis of temporal hierarchy in biochemical reaction networks
-
Jamshidi N., Palsson B.Ã. Top-down analysis of temporal hierarchy in biochemical reaction networks. PLoS Comput Biol 2008, 4:e1000177.
-
(2008)
PLoS Comput Biol
, vol.4
-
-
Jamshidi, N.1
Palsson, B.A.2
-
13
-
-
0037025146
-
Dynamic modeling of the central carbon metabolism of Escherichia coli
-
Chassagnole C., Noisommit-Rizzi N., Schmid J.W., Mauch K., Reuss M. Dynamic modeling of the central carbon metabolism of Escherichia coli. Biotechnol Bioeng 2002, 79:53-73.
-
(2002)
Biotechnol Bioeng
, vol.79
, pp. 53-73
-
-
Chassagnole, C.1
Noisommit-Rizzi, N.2
Schmid, J.W.3
Mauch, K.4
Reuss, M.5
-
14
-
-
60849105949
-
Translating biochemical network models between different kinetic formats
-
Hadlich F., Noack S., Wiechert W. Translating biochemical network models between different kinetic formats. Metab Eng 2009, 11:87-100.
-
(2009)
Metab Eng
, vol.11
, pp. 87-100
-
-
Hadlich, F.1
Noack, S.2
Wiechert, W.3
-
15
-
-
77951978451
-
Dynamic modeling of Escherichia coli metabolic and regulatory systems for amino-acid production
-
Usuda Y., Nishio Y., Iwatani S., Van Dien S.J., Imaizumi A., Shimbo K., Kageyama N., Iwahata D., Miyano H., Matsui K. Dynamic modeling of Escherichia coli metabolic and regulatory systems for amino-acid production. J Biotechnol 2010, 147:17-30.
-
(2010)
J Biotechnol
, vol.147
, pp. 17-30
-
-
Usuda, Y.1
Nishio, Y.2
Iwatani, S.3
Van Dien, S.J.4
Imaizumi, A.5
Shimbo, K.6
Kageyama, N.7
Iwahata, D.8
Miyano, H.9
Matsui, K.10
-
16
-
-
64649089947
-
Cross-platform comparison of methods for quantitative metabolomics of primary metabolism
-
Buscher J.M., Czernik D., Ewald J.C., Sauer U., Zamboni N. Cross-platform comparison of methods for quantitative metabolomics of primary metabolism. Anal Chem 2009, 81:2135-2143.
-
(2009)
Anal Chem
, vol.81
, pp. 2135-2143
-
-
Buscher, J.M.1
Czernik, D.2
Ewald, J.C.3
Sauer, U.4
Zamboni, N.5
-
17
-
-
68049100110
-
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
-
Bennett B.D., Kimball E.H., Gao M., Osterhout R., Van Dien S.J., Rabinowitz J.D. Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. Nat Chem Biol 2009, 5:593-599.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 593-599
-
-
Bennett, B.D.1
Kimball, E.H.2
Gao, M.3
Osterhout, R.4
Van Dien, S.J.5
Rabinowitz, J.D.6
-
18
-
-
77950629593
-
Fast sampling for quantitative microbial metabolomics
-
van Gulik W.M. Fast sampling for quantitative microbial metabolomics. Curr Opin Biotechnol 2010, 21:27-34.
-
(2010)
Curr Opin Biotechnol
, vol.21
, pp. 27-34
-
-
van Gulik, W.M.1
-
19
-
-
62249146094
-
In vivo dynamics of glycolysis in Escherichia coli shows need for growth-rate dependent metabolome analysis
-
Schaub J., Reuss M. In vivo dynamics of glycolysis in Escherichia coli shows need for growth-rate dependent metabolome analysis. Biotechnol Progr 2008, 24:1402-1407.
-
(2008)
Biotechnol Progr
, vol.24
, pp. 1402-1407
-
-
Schaub, J.1
Reuss, M.2
-
20
-
-
67651115487
-
The identification of enzyme targets for the optimization of a valine producing Corynebacterium glutamicum strain using a kinetic model
-
Magnus J.B., Oldiges M., Takors R. The identification of enzyme targets for the optimization of a valine producing Corynebacterium glutamicum strain using a kinetic model. Biotechnol Prog 2009, 25:754-762.
-
(2009)
Biotechnol Prog
, vol.25
, pp. 754-762
-
-
Magnus, J.B.1
Oldiges, M.2
Takors, R.3
-
21
-
-
43149099413
-
13C labeling experiments at metabolic nonstationary conditions: an exploratory study
-
Wahl S., Noh K., Wiechert W. 13C labeling experiments at metabolic nonstationary conditions: an exploratory study. BMC Bioinformat 2008, 9:152.
-
(2008)
BMC Bioinformat
, vol.9
, pp. 152
-
-
Wahl, S.1
Noh, K.2
Wiechert, W.3
-
22
-
-
68749094119
-
Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics
-
Picotti P., Bodenmiller B., Mueller L.N., Domon B., Aebersold R. Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics. Cell 2009, 138:795-806.
-
(2009)
Cell
, vol.138
, pp. 795-806
-
-
Picotti, P.1
Bodenmiller, B.2
Mueller, L.N.3
Domon, B.4
Aebersold, R.5
-
23
-
-
74049131716
-
High-throughput generation of selected reaction-monitoring assays for proteins and proteomes
-
Picotti P., Rinner O., Stallmach R., Dautel F., Farrah T., Domon B., Wenschuh H., Aebersold R. High-throughput generation of selected reaction-monitoring assays for proteins and proteomes. Nat Meth 2010, 7:U43-U45.
-
(2010)
Nat Meth
, vol.7
-
-
Picotti, P.1
Rinner, O.2
Stallmach, R.3
Dautel, F.4
Farrah, T.5
Domon, B.6
Wenschuh, H.7
Aebersold, R.8
-
24
-
-
73149088132
-
Engineering static and dynamic control of synthetic pathways
-
Holtz W.J., Keasling J.D. Engineering static and dynamic control of synthetic pathways. Cell 2010, 140:19-23.
-
(2010)
Cell
, vol.140
, pp. 19-23
-
-
Holtz, W.J.1
Keasling, J.D.2
-
25
-
-
33847083318
-
Global transcription machinery engineering: a new approach for improving cellular phenotype
-
Alper H., Stephanopoulos G. Global transcription machinery engineering: a new approach for improving cellular phenotype. Metab Eng 2007, 9:258-267.
-
(2007)
Metab Eng
, vol.9
, pp. 258-267
-
-
Alper, H.1
Stephanopoulos, G.2
-
26
-
-
68949161807
-
Programming cells by multiplex genome engineering and accelerated evolution
-
Wang H.H., Isaacs F.J., Carr P.A., Sun Z.Z., Xu G., Forest C.R., Church G.M. Programming cells by multiplex genome engineering and accelerated evolution. Nature 2009, 460:894-898.
-
(2009)
Nature
, vol.460
, pp. 894-898
-
-
Wang, H.H.1
Isaacs, F.J.2
Carr, P.A.3
Sun, Z.Z.4
Xu, G.5
Forest, C.R.6
Church, G.M.7
-
27
-
-
70349964350
-
Automated design of synthetic ribosome binding sites to control protein expression
-
Salis H.M., Mirsky E.A., Voigt C.A. Automated design of synthetic ribosome binding sites to control protein expression. Nat Biotech 2009, 27:946-950.
-
(2009)
Nat Biotech
, vol.27
, pp. 946-950
-
-
Salis, H.M.1
Mirsky, E.A.2
Voigt, C.A.3
-
28
-
-
77952310558
-
Promoter knock-in: a novel rational method for the fine tuning of genes
-
De Mey M., Maertens J., Boogmans S., Soetaert W., Vandamme E., Cunin R., Foulquie-Moreno M. Promoter knock-in: a novel rational method for the fine tuning of genes. BMC Biotechnol 2010, 10:26.
-
(2010)
BMC Biotechnol
, vol.10
, pp. 26
-
-
De Mey, M.1
Maertens, J.2
Boogmans, S.3
Soetaert, W.4
Vandamme, E.5
Cunin, R.6
Foulquie-Moreno, M.7
-
29
-
-
24644515752
-
Tuning genetic control through promoter engineering
-
Alper H., Fischer C., Nevoigt E., Stephanopoulos G. Tuning genetic control through promoter engineering. Proc Natl Acad Sci USA 2005, 102:12678-12683.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12678-12683
-
-
Alper, H.1
Fischer, C.2
Nevoigt, E.3
Stephanopoulos, G.4
-
30
-
-
77952477753
-
Pairwise selection assembly for sequence-independent construction of long-length DNA
-
Blake W.J., Chapman B.A., Zindal A., Lee M.E., Lippow S.M., Baynes B.M. Pairwise selection assembly for sequence-independent construction of long-length DNA. Nucl Acids Res 2010, 38:2594-2602.
-
(2010)
Nucl Acids Res
, vol.38
, pp. 2594-2602
-
-
Blake, W.J.1
Chapman, B.A.2
Zindal, A.3
Lee, M.E.4
Lippow, S.M.5
Baynes, B.M.6
-
31
-
-
73349139923
-
Synthesis of DNA fragments in yeast by one-step assembly of overlapping oligonucleotides
-
Gibson D.G. Synthesis of DNA fragments in yeast by one-step assembly of overlapping oligonucleotides. Nucl Acids Res 2009, 37:6984-6990.
-
(2009)
Nucl Acids Res
, vol.37
, pp. 6984-6990
-
-
Gibson, D.G.1
-
32
-
-
58149510036
-
One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome
-
Gibson D.G., Benders G.A., Axelrod K.C., Zaveri J., Algire M.A., Moodie M., Montague M.G., Venter J.C., Smith H.O., Hutchison C.A. One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome. Proc Natl Acad Sci USA 2008, 105:20404-20409.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20404-20409
-
-
Gibson, D.G.1
Benders, G.A.2
Axelrod, K.C.3
Zaveri, J.4
Algire, M.A.5
Moodie, M.6
Montague, M.G.7
Venter, J.C.8
Smith, H.O.9
Hutchison, C.A.10
-
33
-
-
67349270900
-
Enzymatic assembly of DNA molecules up to several hundred kilobases
-
Gibson D.G., Young L., Chuang R.-Y., Venter J.C., Hutchison C.A., Smith H.O. Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat Meth 2009, 6:343-345.
-
(2009)
Nat Meth
, vol.6
, pp. 343-345
-
-
Gibson, D.G.1
Young, L.2
Chuang, R.-Y.3
Venter, J.C.4
Hutchison, C.A.5
Smith, H.O.6
-
34
-
-
43249106821
-
Recursive construction of perfect DNA molecules from imperfect oligonucleotides
-
Linshiz G., Yehezkel T.B., Kaplan S., Gronau I., Ravid S., Adar R., Shapiro E. Recursive construction of perfect DNA molecules from imperfect oligonucleotides. Mol Syst Biol 2008, 4:191.
-
(2008)
Mol Syst Biol
, vol.4
, pp. 191
-
-
Linshiz, G.1
Yehezkel, T.B.2
Kaplan, S.3
Gronau, I.4
Ravid, S.5
Adar, R.6
Shapiro, E.7
-
35
-
-
0036500834
-
Reverse engineering of biological complexity
-
Csete M.E., Doyle J.C. Reverse engineering of biological complexity. Science 2002, 295:1664-1669.
-
(2002)
Science
, vol.295
, pp. 1664-1669
-
-
Csete, M.E.1
Doyle, J.C.2
-
36
-
-
77950445877
-
Microbial systems engineering: first successes and the way ahead
-
Dietz S., Panke S. Microbial systems engineering: first successes and the way ahead. Bioessays 2010, 32:356-362.
-
(2010)
Bioessays
, vol.32
, pp. 356-362
-
-
Dietz, S.1
Panke, S.2
-
37
-
-
66649105445
-
Synthesis of orthogonal transcription-translation networks
-
An W., Chin J.W. Synthesis of orthogonal transcription-translation networks. Proc Natl Acad Sci USA 2009, 106:8477-8482.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 8477-8482
-
-
An, W.1
Chin, J.W.2
-
38
-
-
77949772551
-
Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome
-
Neumann H., Wang K., Davis L., Garcia-Alai M., Chin J.W. Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome. Nature 2010, 464:441-444.
-
(2010)
Nature
, vol.464
, pp. 441-444
-
-
Neumann, H.1
Wang, K.2
Davis, L.3
Garcia-Alai, M.4
Chin, J.W.5
-
39
-
-
68449088806
-
Synthetic protein scaffolds provide modular control over metabolic flux
-
Dueber J.E., Wu G.C., Malmirchegini G.R., Moon T.S., Petzold C.J., Ullal A.V., Prather K.L.J., Keasling J.D. Synthetic protein scaffolds provide modular control over metabolic flux. Nat Biotech 2009, 27:753-759.
-
(2009)
Nat Biotech
, vol.27
, pp. 753-759
-
-
Dueber, J.E.1
Wu, G.C.2
Malmirchegini, G.R.3
Moon, T.S.4
Petzold, C.J.5
Ullal, A.V.6
Prather, K.L.J.7
Keasling, J.D.8
-
40
-
-
77950863739
-
Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli
-
Moon T.S., Dueber J.E., Shiue E., Prather K.L.J. Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli. Meth Eng 2010, 12:298-305.
-
(2010)
Meth Eng
, vol.12
, pp. 298-305
-
-
Moon, T.S.1
Dueber, J.E.2
Shiue, E.3
Prather, K.L.J.4
|