메뉴 건너뛰기




Volumn 25, Issue 3, 2009, Pages 754-762

The identification of enzyme targets for the optimization of a valine producing corynebacterium glutamicum strain using a kinetic model

Author keywords

Kinetic model; Metabolic control analysis; Metabolic engineering; Strain optimization; Valine production

Indexed keywords

KINETIC MODEL; METABOLIC CONTROL ANALYSIS; METABOLIC ENGINEERING; STRAIN OPTIMIZATION; VALINE PRODUCTION;

EID: 67651115487     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1002/btpr.184     Document Type: Article
Times cited : (21)

References (35)
  • 1
    • 0025895183 scopus 로고
    • Towards a science of metabolic engineering
    • Bailey JE. Towards a science of metabolic engineering. Science. 1991;252:1668-1675.
    • (1991) Science , vol.252 , pp. 1668-1675
    • Bailey, J.E.1
  • 3
    • 0015989446 scopus 로고
    • A linear steady-state treatment of enzymatic chains. General properties, control and effector strength
    • Heinrich R, Rapoport TA. A linear steady-state treatment of enzymatic chains. General properties, control and effector strength. Eur J Biochem. 1974;42:89-95.
    • (1974) Eur J Biochem , vol.42 , pp. 89-95
    • Heinrich, R.1    Rapoport, T.A.2
  • 5
    • 0026802334 scopus 로고
    • Metabolic control analysis: A survey of its theoretical and experimental development
    • Fell DA. Metabolic control analysis: a survey of its theoretical and experimental development. Biochem J. 1992;286:313-330.
    • (1992) Biochem J , vol.286 , pp. 313-330
    • Fell, D.A.1
  • 6
    • 0027601708 scopus 로고
    • Advances in metabolic control analysis
    • Liao JC, Delgado J. Advances in metabolic control analysis. Biotechnol Prog. 1993;9:221-233.
    • (1993) Biotechnol Prog , vol.9 , pp. 221-233
    • Liao, J.C.1    Delgado, J.2
  • 7
    • 0036526636 scopus 로고    scopus 로고
    • The mathematics of metabolic control analysis revisited
    • Visser D, Heijnen JJ. The mathematics of metabolic control analysis revisited. Metab Eng. 2002;4:114-123.
    • (2002) Metab Eng , vol.4 , pp. 114-123
    • Visser, D.1    Heijnen, J.J.2
  • 9
    • 6044249046 scopus 로고    scopus 로고
    • Metabolic design based on a coupled gene expression-metabolic network model of tryptophan production in Escherichia coli
    • Schmid JW, Mauch K, Reuss M, Gilles ED, Kremling A. Metabolic design based on a coupled gene expression-metabolic network model of tryptophan production in Escherichia coli. Metab Eng. 2004;6:364-377.
    • (2004) Metab Eng , vol.6 , pp. 364-377
    • Schmid, J.W.1    Mauch, K.2    Reuss, M.3    Gilles, E.D.4    Kremling, A.5
  • 10
    • 0036244782 scopus 로고    scopus 로고
    • Linking central metabolism with increased pathway flux: L-valine accumulation by Corynebacterium glutamicum
    • Radmacher E, Vaitsikova A, Burger U, Krumbach K, Sahm H, Eggeling L. Linking central metabolism with increased pathway flux: L-valine accumulation by Corynebacterium glutamicum. Appl Environ Microbiol. 2002;65:2246-2250.
    • (2002) Appl Environ Microbiol , vol.65 , pp. 2246-2250
    • Radmacher, E.1    Vaitsikova, A.2    Burger, U.3    Krumbach, K.4    Sahm, H.5    Eggeling, L.6
  • 11
    • 33747171718 scopus 로고    scopus 로고
    • Monitoring and modelling of the reaction dynamics in the valine/leucine pathway in Corynebacterium glutamicum
    • Magnus JB, Hollwedel D, Oldiges M, Takors R. Monitoring and modelling of the reaction dynamics in the valine/leucine pathway in Corynebacterium glutamicum. Biotechnol Prog. 2006;22:1071-1083.
    • (2006) Biotechnol Prog , vol.22 , pp. 1071-1083
    • Magnus, J.B.1    Hollwedel, D.2    Oldiges, M.3    Takors, R.4
  • 12
    • 0042932693 scopus 로고    scopus 로고
    • Characterisation of the enzyme activities involved in the valine biosynthesis pathway in a valine producing strain of Corynebacterium glutamicum
    • Leyval D, Uy D, Delaunay S, Goergen JL, Engasser JM. Characterisation of the enzyme activities involved in the valine biosynthesis pathway in a valine producing strain of Corynebacterium glutamicum. J Biotechnol. 2003;104:241-252.
    • (2003) J Biotechnol , vol.104 , pp. 241-252
    • Leyval, D.1    Uy, D.2    Delaunay, S.3    Goergen, J.L.4    Engasser, J.M.5
  • 13
    • 0019751251 scopus 로고
    • Kinetic models of metabolism in intact cells, tissues and organisms
    • Wright BE, Kelly PJ. Kinetic models of metabolism in intact cells, tissues and organisms. Curr Top Cell Regul. 1981;19:103-158.
    • (1981) Curr Top Cell Regul , vol.19 , pp. 103-158
    • Wright, B.E.1    Kelly, P.J.2
  • 15
    • 10044287191 scopus 로고    scopus 로고
    • Stimulation, monitoring and analysis of pathway dynamics by metabolic profiling in the aromatic amino acid pathway
    • Oldiges M, Kunze M, Degenring D, Sprenger GA, Takors R. Stimulation, monitoring and analysis of pathway dynamics by metabolic profiling in the aromatic amino acid pathway. Biotechnol Prog. 2004;20:1623-1633.
    • (2004) Biotechnol Prog , vol.20 , pp. 1623-1633
    • Oldiges, M.1    Kunze, M.2    Degenring, D.3    Sprenger, G.A.4    Takors, R.5
  • 17
    • 0036299777 scopus 로고    scopus 로고
    • Export of isoleucine from Corynebacterium glutamicum: A two-gene-encoded member of a new translocator family
    • Kennerknecht N, Sahm H, Yen M-R, Patek M, Saier MS Jr, Eggeling L. Export of isoleucine from Corynebacterium glutamicum: a two-gene-encoded member of a new translocator family. J Bacteriol. 2002;184:3947-3956.
    • (2002) J Bacteriol , vol.184 , pp. 3947-3956
    • Kennerknecht, N.1    Sahm, H.2    Yen, M.-R.3    Patek, M.4    Saier Jr, M.S.5    Eggeling, L.6
  • 19
    • 0347511691 scopus 로고    scopus 로고
    • Next generation simulation tools: The systems biology workbench and BioSPICE integration
    • Sauro HM, Hucka M, Finney A, Wellock C, Bolouri H, Doyle J, Kitano H. Next generation simulation tools: the systems biology workbench and BioSPICE integration. OMICS. 2003;7:355-372.
    • (2003) OMICS , vol.7 , pp. 355-372
    • Sauro, H.M.1    Hucka, M.2    Finney, A.3    Wellock, C.4    Bolouri, H.5    Doyle, J.6    Kitano, H.7
  • 20
    • 6044260198 scopus 로고    scopus 로고
    • Optimal re-design of primary metabolism in Escherichia coli using linlog kinetics
    • Visser D, Schmid JW, Mauch K, Reuss M, Heijnen JJ. Optimal re-design of primary metabolism in Escherichia coli using linlog kinetics. Metab Eng. 2004;6:378-390.
    • (2004) Metab Eng , vol.6 , pp. 378-390
    • Visser, D.1    Schmid, J.W.2    Mauch, K.3    Reuss, M.4    Heijnen, J.J.5
  • 21
    • 0027301842 scopus 로고
    • A universal method of achieving increases in metabolite production
    • Kacser H, Acerenza L. A universal method of achieving increases in metabolite production. Eur J Biochem. 1993;216: 361-367.
    • (1993) Eur J Biochem , vol.216 , pp. 361-367
    • Kacser, H.1    Acerenza, L.2
  • 22
    • 0030574067 scopus 로고    scopus 로고
    • Design of metabolic control for large flux changes
    • Thomas S, Fell DA. Design of metabolic control for large flux changes. J Theor Biol. 1996;182:285-298.
    • (1996) J Theor Biol , vol.182 , pp. 285-298
    • Thomas, S.1    Fell, D.A.2
  • 23
    • 0031214696 scopus 로고    scopus 로고
    • Flux amplification in complex metabolic networks
    • Stephanopoulos G, Simpson TW. Flux amplification in complex metabolic networks. Chem Eng Sci. 1997;52:2607-2627.
    • (1997) Chem Eng Sci , vol.52 , pp. 2607-2627
    • Stephanopoulos, G.1    Simpson, T.W.2
  • 24
    • 0025701406 scopus 로고
    • Group contributions for estimating standard Gibbs energies of formation of biochemical compounds in aqueous solution
    • Mavrovouniotis ML. Group contributions for estimating standard Gibbs energies of formation of biochemical compounds in aqueous solution. Biotechnol Bioeng. 1990;36:1070-1082.
    • (1990) Biotechnol Bioeng , vol.36 , pp. 1070-1082
    • Mavrovouniotis, M.L.1
  • 25
    • 0026353854 scopus 로고
    • Estimation of standard Gibbs energy changes of biotransformations
    • Mavrovouniotis ML. Estimation of standard Gibbs energy changes of biotransformations. J Biol Chem. 1991;266:14440-14445.
    • (1991) J Biol Chem , vol.266 , pp. 14440-14445
    • Mavrovouniotis, M.L.1
  • 27
    • 0032406131 scopus 로고    scopus 로고
    • Non-linear optimization of biochemical pathways: Applications to metabolic engineering and parameter estimation
    • Mendes P, Kell DB. Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation. Bioinformatics. 1998;14:869-883.
    • (1998) Bioinformatics , vol.14 , pp. 869-883
    • Mendes, P.1    Kell, D.B.2
  • 29
    • 0027974098 scopus 로고
    • Quantitative discrimination of carriermediated excretion of isoleucine from uptake and diffusion in Corynebacterium glutamicum
    • Zitterich S, Krämer R. Quantitative discrimination of carriermediated excretion of isoleucine from uptake and diffusion in Corynebacterium glutamicum. J Bacteriol. 1994;176:6892-6899.
    • (1994) J Bacteriol , vol.176 , pp. 6892-6899
    • Zitterich, S.1    Krämer, R.2
  • 32
    • 0029860181 scopus 로고    scopus 로고
    • L-Isoleucine production with Corynebacterium glutamicum: Further flux increase and limitation of export
    • Morbach S, Sahm H, Eggeling L. L-Isoleucine production with Corynebacterium glutamicum: further flux increase and limitation of export. Appl Environ Microbiol. 1996;62:4345-4351.
    • (1996) Appl Environ Microbiol , vol.62 , pp. 4345-4351
    • Morbach, S.1    Sahm, H.2    Eggeling, L.3
  • 33
    • 0032998388 scopus 로고    scopus 로고
    • Construction of L-isoleucine overproducing strains of Corynebacterium glutamicum
    • Sahm H, Eggeling L, Morbach S. Construction of L-isoleucine overproducing strains of Corynebacterium glutamicum. Naturwissenschaften. 1999;86:33-38.
    • (1999) Naturwissenschaften , vol.86 , pp. 33-38
    • Sahm, H.1    Eggeling, L.2    Morbach, S.3
  • 34
    • 0025822783 scopus 로고
    • Quantitative assessment of regulation in metabolic systems
    • Hofmeyr JHS, Cornish-Bowden A. Quantitative assessment of regulation in metabolic systems. Eur J Biochem. 1991;200:223-236.
    • (1991) Eur J Biochem , vol.200 , pp. 223-236
    • Hofmeyr, J.H.S.1    Cornish-Bowden, A.2
  • 35
    • 0141684666 scopus 로고    scopus 로고
    • Dynamic simulation and metabolic redesign of a branched pathway using linlog kinetics
    • Visser D, Heijnen JJ. Dynamic simulation and metabolic redesign of a branched pathway using linlog kinetics. Metab Eng. 2003;5:164-176.
    • (2003) Metab Eng , vol.5 , pp. 164-176
    • Visser, D.1    Heijnen, J.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.