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Volumn 200, Issue , 2011, Pages 201-234

Theobromine and the pharmacology of cocoa

Author keywords

Chocolate; Cocoa; Comparative; Craving; Liking; Myths; Pharmacology; Psychology; Theobromine; Toxicology

Indexed keywords

ANANDAMIDE; CAFFEINE; DRONABINOL; MAGNESIUM; PHENETHYLAMINE; PLACEBO; SALSOLINOL; SEROTONIN; THEOBROMINE; THEOPHYLLINE; TRYPTOLINE DERIVATIVE; TRYPTOPHAN; TYRAMINE;

EID: 77957553531     PISSN: 01712004     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-13443-2_7     Document Type: Review
Times cited : (76)

References (217)
  • 2
    • 0001841576 scopus 로고    scopus 로고
    • Methylxanthine composition and consumption patterns of cocoa and chocolate products
    • Spiller GA ed, 1st edn. CRC, Boca Raton
    • Apgar JL, Tarka SM Jr (1998) Methylxanthine composition and consumption patterns of cocoa and chocolate products. In: Spiller GA (ed) Caffeine, 1st edn. CRC, Boca Raton
    • (1998) Caffeine
    • Apgar, J.L.1    Tarka Jr., S.M.2
  • 4
    • 77957571130 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of natural methylxanthines in animal and man
    • Fredholm BB ed, Springer, Heidelberg
    • Arnaud M (2010) Pharmacokinetics and metabolism of natural methylxanthines in animal and man. In: Fredholm BB (ed) Methylxanthines. Springer, Heidelberg
    • (2010) Methylxanthines
    • Arnaud, M.1
  • 5
    • 39149121177 scopus 로고    scopus 로고
    • Caffeine and related purine alkaloids: Biosynthesis, catabolism, function and genetic engineering
    • Ashihara H, Sano H, Crozier A (2008) Caffeine and related purine alkaloids: biosynthesis, catabolism, function and genetic engineering. Phytochemistry 69:841-856
    • (2008) Phytochemistry , vol.69 , pp. 841-856
    • Ashihara, H.1    Sano, H.2    Crozier, A.3
  • 6
    • 77957583919 scopus 로고    scopus 로고
    • Distribution, biosynthesis and catabolism of methylxanthines in plants
    • Fredholm BB ed, Springer, Heidelberg
    • Ashihara H, Kato M, Crozier A (2010) Distribution, biosynthesis and catabolism of methylxanthines in plants. In: Fredholm BB (ed) Methylxanthines. Springer, Heidelberg
    • (2010) Methylxanthines
    • Ashihara, H.1    Kato, M.2    Crozier, A.3
  • 7
    • 1542582134 scopus 로고
    • Lebensmittelvergiftung. I. Toxine in Natürlichen Lebensmitteln
    • Askar A, Morad MM (1980) Lebensmittelvergiftung. I. Toxine in Natürlichen Lebensmitteln. Alimenta 19:59-66
    • (1980) Alimenta , vol.19 , pp. 59-66
    • Askar, A.1    Morad, M.M.2
  • 8
    • 0142058766 scopus 로고    scopus 로고
    • Antioxidant and prooxidant properties of caffeine, theobromine and xanthine
    • Azam S, Hadi N, Khan NU et al (2003) Antioxidant and prooxidant properties of caffeine, theobromine and xanthine. Med Sci Monit 9: BR325-BR330
    • (2003) Med. Sci. Monit. , vol.9
    • Azam, S.1    Hadi, N.2    Khan, N.U.3
  • 9
  • 10
    • 0024271651 scopus 로고
    • Food craving, mood and the menstrual cycle
    • Bancroft J, Cook A, Williamson L (1988) Food craving, mood and the menstrual cycle. Psychol Med 18:855-860
    • (1988) Psychol. Med. , vol.18 , pp. 855-860
    • Bancroft, J.1    Cook, A.2    Williamson, L.3
  • 11
    • 0035226441 scopus 로고    scopus 로고
    • Caffeine for asthma
    • Art No CD001112. doi:001110.001002/14651858
    • Bara A, Barley E (2001) Caffeine for asthma. Cochrane Database Syst Rev (4) Art No CD001112. doi:001110.001002/14651858
    • (2001) Cochrane Database Syst. Rev. , Issue.4
    • Bara, A.1    Barley, E.2
  • 12
    • 0034320493 scopus 로고    scopus 로고
    • Adenosine receptor antagonism causes inhibition of angiogenic activity of human ovarian cancer cells
    • Barcz E, Sommer E, Janik P et al (2000) Adenosine receptor antagonism causes inhibition of angiogenic activity of human ovarian cancer cells. Oncol Rep 7:1285-1291
    • (2000) Oncol. Rep. , vol.7 , pp. 1285-1291
    • Barcz, E.1    Sommer, E.2    Janik, P.3
  • 13
    • 0031910614 scopus 로고    scopus 로고
    • The influence of theobromine on angiogenic activity and proangiogenic cytokines production of human ovarian cancer cells
    • Barcz E, Sommer E, Sokolnicka I et al (1998) The influence of theobromine on angiogenic activity and proangiogenic cytokines production of human ovarian cancer cells. Oncol Rep 5:517-520
    • (1998) Oncol. Rep. , vol.5 , pp. 517-520
    • Barcz, E.1    Sommer, E.2    Sokolnicka, I.3
  • 14
    • 0028348391 scopus 로고
    • Theophylline in the management of asthma: Time for reappraisal?
    • Barnes PJ, Pauwels RA (1994) Theophylline in the management of asthma: time for reappraisal? Eur Respir J 7:579-591
    • (1994) Eur. Respir. J. , vol.7 , pp. 579-591
    • Barnes, P.J.1    Pauwels, R.A.2
  • 15
    • 0033179869 scopus 로고    scopus 로고
    • Hemodynamic and electrophysiologic effects of acute chocolate ingestion in young adults
    • Baron AM, Donnerstein RL, Samson RA et al (1999) Hemodynamic and electrophysiologic effects of acute chocolate ingestion in young adults. Am J Cardiol 84:370-373
    • (1999) Am. J. Cardiol. , vol.84 , pp. 370-373
    • Baron, A.M.1    Donnerstein, R.L.2    Samson, R.A.3
  • 16
    • 0021345669 scopus 로고
    • The bronchodilator effects and pharmacokinetics of caffeine in asthma
    • Becker AB, Simons KJ, Gillespie CA et al (1984) The bronchodilator effects and pharmacokinetics of caffeine in asthma. N Engl J Med 310:743-746
    • (1984) N. Engl. J. Med. , vol.310 , pp. 743-746
    • Becker, A.B.1    Simons, K.J.2    Gillespie, C.A.3
  • 17
    • 53849098350 scopus 로고    scopus 로고
    • Inhibitory activity of the novel CB2 receptor agonist, GW833972A, on guinea-pig and human sensory nerve function in the airways
    • Belvisi MG, Patel HJ, Freund-Michel V et al (2008) Inhibitory activity of the novel CB2 receptor agonist, GW833972A, on guinea-pig and human sensory nerve function in the airways. Br J Pharmacol 155:547-557
    • (2008) Br. J. Pharmacol. , vol.155 , pp. 547-557
    • Belvisi, M.G.1    Patel, H.J.2    Freund-Michel, V.3
  • 19
    • 0040972824 scopus 로고
    • Observations on the feeding of a cacao waste product to poultry
    • Black D J G, Barron NS (1943) Observations on the feeding of a cacao waste product to poultry. Vet Rec 55:166-167
    • (1943) Vet. Rec. , vol.55 , pp. 166-167
    • Black, D.J.G.1    Barron, N.S.2
  • 20
    • 0039193904 scopus 로고
    • The poisoning of livestock by cacao products
    • Blakemore F, Shearer GD (1943) The poisoning of livestock by cacao products. Vet Rec 55:165
    • (1943) Vet. Rec. , vol.55 , pp. 165
    • Blakemore, F.1    Shearer, G.D.2
  • 21
    • 0021319608 scopus 로고
    • Kinetics and metabolism of theobromine in male rats
    • Bonati M, Latini R, Sadurska B et al (1984) Kinetics and metabolism of theobromine in male rats. Toxicol 30:327-341
    • (1984) Toxicol. , vol.30 , pp. 327-341
    • Bonati, M.1    Latini, R.2    Sadurska, B.3
  • 22
    • 0000218459 scopus 로고    scopus 로고
    • Evaluation of purine alkaloids and diketopiperazines contents in processed cocoa powder
    • Bonvehi JS, Coll FV (2000) Evaluation of purine alkaloids and diketopiperazines contents in processed cocoa powder. Eur Food Res Technol 210:189-195
    • (2000) Eur. Food Res. Technol. , vol.210 , pp. 189-195
    • Bonvehi, J.S.1    Coll, F.V.2
  • 24
    • 33746988541 scopus 로고    scopus 로고
    • Determination of theobromine, theophylline and caffeine in cocoa samples by a high-performance liquid chromatographic method with online sample cleanup in a switching-column system
    • Brunetto Md R, Gutiérrez L, Delgado Y et al (2007) Determination of theobromine, theophylline and caffeine in cocoa samples by a high-performance liquid chromatographic method with online sample cleanup in a switching-column system. Food Chem 100:459-467
    • (2007) Food Chem. , vol.100 , pp. 459-467
    • Md, R.B.1    Gutiérrez, L.2    Delgado, Y.3
  • 25
    • 77049122865 scopus 로고    scopus 로고
    • Caffeine and theobromine identifications in postrace urines: Threshold levels and regulatory significance of such identifications
    • Budhraja A, Camargo FC, Hughes C et al (2007) Caffeine and theobromine identifications in postrace urines: threshold levels and regulatory significance of such identifications. AAEP Proc 53:87-94
    • (2007) AAEP Proc. , vol.53 , pp. 87-94
    • Budhraja, A.1    Camargo, F.C.2    Hughes, C.3
  • 26
    • 68749120625 scopus 로고    scopus 로고
    • Safety assessment of kola nut extract as a food ingredient
    • Burdock GA, Carabin IG, Crincoli CM (2009) Safety assessment of kola nut extract as a food ingredient. Food Chem Toxicol 47:1725-1732
    • (2009) Food Chem. Toxicol. , vol.47 , pp. 1725-1732
    • Burdock, G.A.1    Carabin, I.G.2    Crincoli, C.M.3
  • 27
    • 34548357156 scopus 로고    scopus 로고
    • 2 extraction of purine alkaloids in different Ilex paraguariensis progenies grown under environmental influences
    • 2 extraction of purine alkaloids in different Ilex paraguariensis progenies grown under environmental influences. J Agric Food Chem 22:6835-6841
    • (2007) J. Agric. Food Chem. , vol.22 , pp. 6835-6841
    • Cardozo Jr., E.L.1    Cardozo-Filho, L.2    Filho, O.F.3
  • 28
    • 0021814239 scopus 로고
    • Discriminative stimulus properties of methylxanthines and their metabolites in rats
    • Carney JM, Holloway FA, Modrow HE (1985) Discriminative stimulus properties of methylxanthines and their metabolites in rats. Life Sci 36:913-920
    • (1985) Life Sci. , vol.36 , pp. 913-920
    • Carney, J.M.1    Holloway, F.A.2    Modrow, H.E.3
  • 29
    • 37349076495 scopus 로고    scopus 로고
    • A multidimensional ambivalence model of chocolate craving: Construct validity and associations with chocolate consumption and disordered eating
    • Cartwright F, Stritzke WG (2008) A multidimensional ambivalence model of chocolate craving: construct validity and associations with chocolate consumption and disordered eating. Eat Behav 9:1-12
    • (2008) Eat Behav. , vol.9 , pp. 1-12
    • Cartwright, F.1    Stritzke, W.G.2
  • 30
    • 84873784928 scopus 로고
    • Inhibition par les sucres de l'effet excitant qu'exercent les bases puriques sur le système nerveux
    • Chauchard P, Mazoué H, Lecoq R (1945) Inhibition par les sucres de l'effet excitant qu'exercent les bases puriques sur le système nerveux. Soc Biol Seance 12-13
    • (1945) Soc. Biol. Seance , pp. 12-13
    • Chauchard, P.1    Mazoué, H.2    Lecoq, R.3
  • 31
    • 8844287593 scopus 로고    scopus 로고
    • Multiple effects of theobromine on fetus development and postnatal status of the immune system
    • Chorostowska-Wynimko J, Skopinska-Rózewska E, Sommer E et al (2004) Multiple effects of theobromine on fetus development and postnatal status of the immune system. Int J Tissue React 26:53-60
    • (2004) Int. J. Tissue React , vol.26 , pp. 53-60
    • Chorostowska-Wynimko, J.1    Skopinska-Rózewska, E.2    Sommer, E.3
  • 33
    • 42149152061 scopus 로고    scopus 로고
    • Prevalence, pathogenesis, and causes of chronic cough
    • Chung KF, Pavord ID (2008) Prevalence, pathogenesis, and causes of chronic cough. Lancet 371:1364-1374
    • (2008) Lancet , vol.371 , pp. 1364-1374
    • Chung, K.F.1    Pavord, I.D.2
  • 34
    • 0000802359 scopus 로고
    • A study of the metabolism of theobromine, theophylline, and caffeine in man
    • Cornish HH, Christman AA (1957) A study of the metabolism of theobromine, theophylline, and caffeine in man. J Biol Chem 228:315-323
    • (1957) J. Biol. Chem. , vol.228 , pp. 315-323
    • Cornish, H.H.1    Christman, A.A.2
  • 35
    • 85013194526 scopus 로고
    • Caffeine and theobromine levels in cocoa and carob products
    • Craig WJ, Nguyen TT (1984) Caffeine and theobromine levels in cocoa and carob products. J Food Sci 49:302-305
    • (1984) J. Food Sci. , vol.49 , pp. 302-305
    • Craig, W.J.1    Nguyen, T.T.2
  • 36
    • 77957601514 scopus 로고    scopus 로고
    • Why we love and lust: How our sex hormones influence our relationships
    • London
    • Crenshaw TL (1996) Why we love and lust: how our sex hormones influence our relationships. Harper Collins, London
    • (1996) Harper Collins
    • Crenshaw, T.L.1
  • 37
    • 0040972826 scopus 로고
    • Suspected chocolate poisoning of calves
    • Curtis PE, Griffiths JE (1972) Suspected chocolate poisoning of calves. Vet Rec 90:313-314
    • (1972) Vet. Rec. , vol.90 , pp. 313-314
    • Curtis, P.E.1    Griffiths, J.E.2
  • 38
    • 0016316759 scopus 로고
    • Zur Frage der biologischen Wirksamkeit von Methylxanthinen in Kakaoprodukten
    • Czok G (1974) Zur Frage der biologischen Wirksamkeit von Methylxanthinen in Kakaoprodukten. Z Ernahrungswiss 13:165-171
    • (1974) Z. Ernahrungswiss , vol.13 , pp. 165-171
    • Czok, G.1
  • 39
    • 0020960991 scopus 로고
    • Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines
    • Daly JW, Butts-Lamb P, Padgett W (1983) Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines. Cell Mol Neurobiol 3:69-80
    • (1983) Cell. Mol. Neurobiol. , vol.3 , pp. 69-80
    • Daly, J.W.1    Butts-Lamb, P.2    Padgett, W.3
  • 41
    • 0040953823 scopus 로고
    • HPLC determination of caffeine and theobromine content of various natural and red dutched cocoas
    • De Vries JW, Johnson KD, Heroff JC (1981) HPLC determination of caffeine and theobromine content of various natural and red dutched cocoas. J Food Sci 46:1968-1969
    • (1981) J. Food Sci. , vol.46 , pp. 1968-1969
    • De Vries, J.W.1    Johnson, K.D.2    Heroff, J.C.3
  • 42
    • 0026101547 scopus 로고
    • Urinary excretion of theobromine in horses given contaminated pelleted food
    • Delbeke FT, Debackere M (1991) Urinary excretion of theobromine in horses given contaminated pelleted food. Vet Res Commun 15:107-116
    • (1991) Vet. Res. Commun. , vol.15 , pp. 107-116
    • Delbeke, F.T.1    Debackere, M.2
  • 43
    • 0343252918 scopus 로고    scopus 로고
    • Trick or treat from food endocannabinoids?
    • Di Marzo V, Sepe N, De Petrocellis L et al (1998) Trick or treat from food endocannabinoids? Nature 396:636
    • (1998) Nature , vol.396 , pp. 636
    • Di Marzo, V.1    Sepe, N.2    De Petrocellis, L.3
  • 45
    • 77957594904 scopus 로고
    • The use of theobromine for pain of arteriosclerotic origin
    • Dock W (1926) The use of theobromine for pain of arteriosclerotic origin. Cal West Med 25:636-638
    • (1926) Cal West Med. , vol.25 , pp. 636-638
    • Dock, W.1
  • 46
    • 0014876552 scopus 로고
    • Comparative stimulant and diuretic actions of caffeine and theobromine in man
    • Dorfman LJ, Jarvik ME (1970) Comparative stimulant and diuretic actions of caffeine and theobromine in man. Clin Pharmacol Ther 11:869-872
    • (1970) Clin. Pharmacol. Ther. , vol.11 , pp. 869-872
    • Dorfman, L.J.1    Jarvik, M.E.2
  • 47
    • 77957598495 scopus 로고    scopus 로고
    • Dorland's Illustrated Medical Dictionary, Saunders Elsevier, Philadelphia
    • Dorland's Illustrated Medical Dictionary (2007) Saunders Elsevier, Philadelphia
    • (2007)
  • 48
    • 77957577637 scopus 로고
    • Note on the quantity of theobromine in the milk of cows fed on a diet including this alkaloid
    • Dowden HC (1938) Note on the quantity of theobromine in the milk of cows fed on a diet including this alkaloid. Biochem J 32:71-73
    • (1938) Biochem. J. , vol.32 , pp. 71-73
    • Dowden, H.C.1
  • 50
    • 0042978433 scopus 로고    scopus 로고
    • Trace elements, toxin and drug elimination in hair with particular reference to the horse
    • Dunnett M, Lees P (2003) Trace elements, toxin and drug elimination in hair with particular reference to the horse. Res Vet Sci 75:89-101
    • (2003) Res. Vet. Sci. , vol.75 , pp. 89-101
    • Dunnett, M.1    Lees, P.2
  • 51
    • 24644459760 scopus 로고    scopus 로고
    • Reduced appetite for caffeine in adenosine A2A receptor knockout mice
    • El Yacoubi M, Ledent C, Parmentier M et al (2005) Reduced appetite for caffeine in adenosine A2A receptor knockout mice. Eur J Pharmacol 519:290-291
    • (2005) Eur. J. Pharmacol. , vol.519 , pp. 290-291
    • El Yacoubi, M.1    Ledent, C.2    Parmentier, M.3
  • 53
    • 54249161484 scopus 로고    scopus 로고
    • The cough from hell: Diazepam for intractable cough in a patient with renal cell carcinoma
    • Estfan B, Walsh D (2008) The cough from hell: diazepam for intractable cough in a patient with renal cell carcinoma. J Pain Symptom Manage 36:553-558
    • (2008) J. Pain Symptom Manage , vol.36 , pp. 553-558
    • Estfan, B.1    Walsh, D.2
  • 54
    • 61449097026 scopus 로고    scopus 로고
    • Theobromine as undesirable substances in animal feed
    • European Food Safety Authority
    • European Food Safety Authority (2008) Theobromine as undesirable substances in animal feed. EFSA J 725:1-66
    • (2008) EFSA J. , vol.725 , pp. 1-66
  • 56
    • 0003634335 scopus 로고    scopus 로고
    • McCance and Widdowson's the composition of foods. Sixth summary edition
    • Food Standards Agency, Cambridge
    • Food Standards Agency (2002) McCance and Widdowson's the composition of foods. Sixth summary edition. Royal Society of Chemistry, Cambridge
    • (2002) Royal Society of Chemistry
  • 57
    • 0345561561 scopus 로고    scopus 로고
    • Actions of caffeine in the brain with special reference to factors that contribute to its widespread use
    • Fredholm BB, Bättig K, Holmén J et al (1999) Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev 51:83-133
    • (1999) Pharmacol. Rev. , vol.51 , pp. 83-133
    • Fredholm, B.B.1    Bättig, K.2    Holmén, J.3
  • 59
    • 0018307048 scopus 로고
    • Testicular atrophy and impaired spermatogenesis in rats fed high levels of the methylxanthines caffeine, theobromine, or theophylline
    • Friedman L, Weinberger MA, Farber TM et al (1979) Testicular atrophy and impaired spermatogenesis in rats fed high levels of the methylxanthines caffeine, theobromine, or theophylline. J Environ Path Toxicol 2:287-706
    • (1979) J. Environ. Path Toxicol. , vol.2 , pp. 287-706
    • Friedman, L.1    Weinberger, M.A.2    Farber, T.M.3
  • 60
    • 0033660212 scopus 로고    scopus 로고
    • Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 22). Effects of 2-and 4-week administration of theobromine on the testis
    • Funabashi H, Fujioka M, Kohchi M et al (2000) Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats 22). Effects of 2-and 4-week administration of theobromine on the testis. J Toxicol Sci 25:211-221
    • (2000) J. Toxicol. Sci. , vol.25 , pp. 211-221
    • Funabashi, H.1    Fujioka, M.2    Kohchi, M.3
  • 61
    • 0020054140 scopus 로고
    • Dietary influences on theobromine-induced toxicity in rats
    • Gans JH (1982) Dietary influences on theobromine-induced toxicity in rats. Toxicol Appl Pharmacol 63:312-320
    • (1982) Toxicol. Appl. Pharmacol. , vol.63 , pp. 312-320
    • Gans, J.H.1
  • 62
    • 0021280319 scopus 로고
    • Comparative toxicities of dietary caffeine and theobromine in the rat
    • Gans JH (1984) Comparative toxicities of dietary caffeine and theobromine in the rat. Food Chem Toxicol 22:365-369
    • (1984) Food Chem. Toxicol. , vol.22 , pp. 365-369
    • Gans, J.H.1
  • 63
    • 0018897859 scopus 로고
    • Effects of short-term and long-term theobromine administration to male dogs
    • Gans JH, Korson R, Cater MR et al (1980) Effects of short-term and long-term theobromine administration to male dogs. Toxicol Appl Pharmacol 53:481-496
    • (1980) Toxicol. Appl. Pharmacol. , vol.53 , pp. 481-496
    • Gans, J.H.1    Korson, R.2    Cater, M.R.3
  • 64
    • 34250870823 scopus 로고    scopus 로고
    • Death by chocolate: A fatal problem for an inquisitive wild parrot
    • Gartrell BD, Reid C (2007) Death by chocolate: a fatal problem for an inquisitive wild parrot. N Z Vet J 55:149-151
    • (2007) N. Z. Vet. J. , vol.55 , pp. 149-151
    • Gartrell, B.D.1    Reid, C.2
  • 65
    • 0033030476 scopus 로고    scopus 로고
    • Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism
    • Gates S, Miners JO (1999) Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism. Br J Clin Pharmacol 47:299-305
    • (1999) Br. J. Clin. Pharmacol. , vol.47 , pp. 299-305
    • Gates, S.1    Miners, J.O.2
  • 66
    • 33748068455 scopus 로고    scopus 로고
    • Caffeine metabolites are inhibitors of the nuclear enzyme poly (ADP-ribose) polymerase-1 at physiological concentrations
    • Geraets L, Moonen HJ, Wouters EF et al (2006) Caffeine metabolites are inhibitors of the nuclear enzyme poly (ADP-ribose) polymerase-1 at physiological concentrations. Biochem Pharmacol 72:902-910
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 902-910
    • Geraets, L.1    Moonen, H.J.2    Wouters, E.F.3
  • 67
    • 61449182765 scopus 로고    scopus 로고
    • Correlation analysis of cocoa consumption data with worldwide incidence rates of testicular cancer and hypospadias
    • Giannandrea F (2009) Correlation analysis of cocoa consumption data with worldwide incidence rates of testicular cancer and hypospadias. Int J Environ Res Public Health 6:568-578
    • (2009) Int. J. Environ. Res. Public Health , vol.6 , pp. 568-578
    • Giannandrea, F.1
  • 68
    • 77957556614 scopus 로고
    • Assessment of calcium, phosphorus, and magnesium status
    • Oxford University Press, Oxford
    • Gibson RS (1990) Assessment of calcium, phosphorus, and magnesium status. Principles of nutritional assessment. Oxford University Press, Oxford
    • (1990) Principles of Nutritional Assessment
    • Gibson, R.S.1
  • 69
    • 0027517996 scopus 로고
    • Effect of purinergic receptor antagonists suramin and theobromine on tumor-induced angiogenesis in balb/c mice
    • Gil M, Skopinska-Rózewska E, Radomska D et al (1993) Effect of purinergic receptor antagonists suramin and theobromine on tumor-induced angiogenesis in balb/c mice. Folia Biol (Praha) 39:63-68
    • (1993) Folia Biol. (Praha) , vol.39 , pp. 63-68
    • Gil, M.1    Skopinska-Rózewska, E.2    Radomska, D.3
  • 70
    • 15744388677 scopus 로고    scopus 로고
    • Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons
    • Grassi D, Lippi C, Necozione S et al (2005) Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons. Am J Clin Nutr 81:611-614
    • (2005) Am. J. Clin. Nutr. , vol.81 , pp. 611-614
    • Grassi, D.1    Lippi, C.2    Necozione, S.3
  • 71
    • 0039193903 scopus 로고
    • Theobromine poisoning in ducks due to the feeding of cacao waste products
    • Gunning OV (1950) Theobromine poisoning in ducks due to the feeding of cacao waste products. Br Vet J 106:31-32
    • (1950) Br. Vet. J. , vol.106 , pp. 31-32
    • Gunning, O.V.1
  • 72
    • 6444245322 scopus 로고    scopus 로고
    • Assay of salsolinol in peripheral blood mononuclear cells of alcoholics and healthy subjects by gas chromatography-mass spectrometry
    • Haber H, Jahn H, Ehrenreich H et al (2002) Assay of salsolinol in peripheral blood mononuclear cells of alcoholics and healthy subjects by gas chromatography-mass spectrometry. Addict Biol 7:403-407
    • (2002) Addict Biol. , vol.7 , pp. 403-407
    • Haber, H.1    Jahn, H.2    Ehrenreich, H.3
  • 73
    • 33947136926 scopus 로고    scopus 로고
    • Chocolate as a cough suppressant: Rationale and justification for an upcoming clinical trial
    • Halfdanarson TR, Jatoi A (2007) Chocolate as a cough suppressant: rationale and justification for an upcoming clinical trial. Support Cancer Ther 4:119-122
    • (2007) Support Cancer Ther. , vol.4 , pp. 119-122
    • Halfdanarson, T.R.1    Jatoi, A.2
  • 74
    • 10944273031 scopus 로고
    • Why the lady loves C6H5 (CH2) 2NH2
    • Hamilton S (1992) Why the lady loves C6H5 (CH2) 2NH2. New Sci 132:26-28
    • (1992) New Sci. , vol.132 , pp. 26-28
    • Hamilton, S.1
  • 76
    • 67349178445 scopus 로고    scopus 로고
    • Polyphenolic beverages reduce initial bacterial adherence to enamel in situ
    • Hannig C, Sorg J, Spitzmüller B et al (2009) Polyphenolic beverages reduce initial bacterial adherence to enamel in situ. J Dent 37:560-566
    • (2009) J. Dent. , vol.37 , pp. 560-566
    • Hannig, C.1    Sorg, J.2    Spitzmüller, B.3
  • 77
    • 0141590382 scopus 로고    scopus 로고
    • Vasoconstrictor and vasodilator effects of adenosine in the kidney
    • Hansen PB, Schnermann J (2003) Vasoconstrictor and vasodilator effects of adenosine in the kidney. Am J Physiol Renal Physiol 285: F590-F599
    • (2003) Am. J. Physiol. Renal Physiol. , vol.285
    • Hansen, P.B.1    Schnermann, J.2
  • 78
    • 0025458640 scopus 로고
    • The excretion of theobromine in thoroughbred racehorses after feeding compounded cubes containing cocoa husk establishment of a threshold value in horse urine
    • Haywood PE, Teale P, Moss MS (1990) The excretion of theobromine in thoroughbred racehorses after feeding compounded cubes containing cocoa husk establishment of a threshold value in horse urine. Equine Vet J 22:244-246
    • (1990) Equine Vet. J. , vol.22 , pp. 244-246
    • Haywood, P.E.1    Teale, P.2    Moss, M.S.3
  • 79
    • 67149099130 scopus 로고    scopus 로고
    • Effect of cocoa tea (Camellia ptilophylla) co-administrated with green tea on ambulatory behaviors
    • He R, Xie G, Yao X-S et al (2009) Effect of cocoa tea (Camellia ptilophylla) co-administrated with green tea on ambulatory behaviors. Biosci Biotechnol Biochem 73:957-960
    • (2009) Biosci. Biotechnol. Biochem. , vol.73 , pp. 957-960
    • He, R.1    Xie, G.2    Yao, X.-S.3
  • 80
    • 0015096330 scopus 로고
    • Coffein-antagonistische Wirkungen des Theobromins und coffeinartige Eigenschaften von Theobromin-Metaboliten
    • Heim F, Hach B, Mitznegg P et al (1971) Coffein-antagonistische Wirkungen des Theobromins und coffeinartige Eigenschaften von Theobromin-Metaboliten. Arzneimittelforschung (Drug Res) 21:1039-1043
    • (1971) Arzneimittelforschung (Drug Res) , vol.21 , pp. 1039-1043
    • Heim, F.1    Hach, B.2    Mitznegg, P.3
  • 81
    • 0033782286 scopus 로고    scopus 로고
    • Tetrahydro-ß-carbolines, potential neuroactive alkaloids, in chocolate and cocoa
    • Herraiz T (2000) Tetrahydro-ß-carbolines, potential neuroactive alkaloids, in chocolate and cocoa. J Agric Food Chem 48:4900-4904
    • (2000) J. Agric. Food Chem. , vol.48 , pp. 4900-4904
    • Herraiz, T.1
  • 82
    • 30544432396 scopus 로고    scopus 로고
    • Human monoamine oxidase enzyme inhibition by coffee and h-carbolines norharman and harman isolated from coffee
    • Herraiz T, Chaparro C (2006) Human monoamine oxidase enzyme inhibition by coffee and h-carbolines norharman and harman isolated from coffee. Life Sci 78:795-802
    • (2006) Life Sci. , vol.78 , pp. 795-802
    • Herraiz, T.1    Chaparro, C.2
  • 83
    • 0000161873 scopus 로고
    • 1,2,3,4-Tetrahydro-ß-carboline-3-carboxylic acid and 1-methyl-1,2,3,4-tetrahydro-ß-carboline-3-carboxylic acid in wines
    • Herraiz T, Huang Z, Ough CS (1993) 1,2,3,4-Tetrahydro-ß-carboline- 3-carboxylic acid and 1-methyl-1,2,3,4-tetrahydro-ß-carboline-3-carboxylic acid in wines. J Agric Food Chem 41:455-459
    • (1993) J. Agric. Food Chem. , vol.41 , pp. 455-459
    • Herraiz, T.1    Huang, Z.2    Ough, C.S.3
  • 84
    • 0030118206 scopus 로고    scopus 로고
    • Tea preparation and its influence on methylxanthine concentration
    • Hicks MB, Hsieh Y-HP, Bell LN (1996) Tea preparation and its influence on methylxanthine concentration. Food Res Int 29:325-330
    • (1996) Food Res. Int. , vol.29 , pp. 325-330
    • Hicks, M.B.1    Hsieh, Y.-H.P.2    Bell, L.N.3
  • 85
    • 0028565967 scopus 로고
    • The experience of food craving; a prospective investigation in healthy women
    • Hill AJ, Heaton-Brown L (1994) The experience of food craving; a prospective investigation in healthy women. J Psychosom Res 38:801-814
    • (1994) J. Psychosom. Res. , vol.38 , pp. 801-814
    • Hill, A.J.1    Heaton-Brown, L.2
  • 88
    • 0019557990 scopus 로고
    • High-performance liquid chromatographic determination of four biogenic amines in chocolate
    • Hurst WJ, Toomey PB (1981) High-performance liquid chromatographic determination of four biogenic amines in chocolate. Analyst 106:394-402
    • (1981) Analyst , vol.106 , pp. 394-402
    • Hurst, W.J.1    Toomey, P.B.2
  • 91
    • 43349089750 scopus 로고    scopus 로고
    • International Federation of Horseracing Authorities, Article 6, Accessed 12 Jun. 2009
    • International Federation of Horseracing Authorities (2007) International agreement on breeding, racing and wagering. Article 6. http://www. horseracingintfed.com/resources/2007-choose-engpdf. Accessed 12 Jun. 2009
    • (2007) International Agreement on Breeding, Racing and Wagering
  • 92
    • 0018602895 scopus 로고
    • Effects of caffeine and various xanthines on hornets and bees
    • Ishay JS, Paniry VA (1979) Effects of caffeine and various xanthines on hornets and bees. Psychopharmacology 65:299-309
    • (1979) Psychopharmacology , vol.65 , pp. 299-309
    • Ishay, J.S.1    Paniry, V.A.2
  • 94
    • 0035319275 scopus 로고    scopus 로고
    • Theobromine intoxication in a red fox and a European badger
    • Jansson DS, Galgan V, Schubert B et al (2001) Theobromine intoxication in a red fox and a European badger. J Wildl Dis 37:362-365
    • (2001) J. Wildl. Dis. , vol.37 , pp. 362-365
    • Jansson, D.S.1    Galgan, V.2    Schubert, B.3
  • 95
    • 20844456446 scopus 로고    scopus 로고
    • Evaluation of cocoa-and coffee-derived methylxanthines as toxicants for the control of pest coyotes
    • Johnston JJ (2005) Evaluation of cocoa-and coffee-derived methylxanthines as toxicants for the control of pest coyotes. J Agric Food Chem 53:4069-4075
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 4069-4075
    • Johnston, J.J.1
  • 96
    • 0023886235 scopus 로고
    • The biogenic amine contents of Dutch cheese and their toxicological significance
    • Joosten H M L J (1988) The biogenic amine contents of Dutch cheese and their toxicological significance. Neth Milk Dairy J 42:25-42
    • (1988) Neth Milk Dairy J. , vol.42 , pp. 25-42
    • Joosten, H.M.L.J.1
  • 97
    • 33745958257 scopus 로고    scopus 로고
    • In-vitro effects of polyphenols from cocoa and betasitosterol on the growth of human prostate cancer and normal cells
    • Jourdain C, Tenca G, Deguercy A et al (2006) In-vitro effects of polyphenols from cocoa and betasitosterol on the growth of human prostate cancer and normal cells. Eur J Cancer Prev 15:353-361
    • (2006) Eur. J. Cancer Prev. , vol.15 , pp. 353-361
    • Jourdain, C.1    Tenca, G.2    Deguercy, A.3
  • 98
    • 0022326290 scopus 로고
    • In-vitro inhibition of glucosyltransferase from the dental plaque bacterium Streptococcus mutans by common beverages and food extracts
    • Kashket S, Paolino VJ, Lewis DA et al (1985) In-vitro inhibition of glucosyltransferase from the dental plaque bacterium Streptococcus mutans by common beverages and food extracts. Arch Oral Biol 30:821-826
    • (1985) Arch. Oral. Biol. , vol.30 , pp. 821-826
    • Kashket, S.1    Paolino, V.J.2    Lewis, D.A.3
  • 99
    • 24044554906 scopus 로고    scopus 로고
    • Effects of theobromine should be considered in future studies
    • Kelly CJ (2005) Effects of theobromine should be considered in future studies. Am J Clin Nutr 82:486-487
    • (2005) Am. J. Clin. Nutr. , vol.82 , pp. 486-487
    • Kelly, C.J.1
  • 100
    • 84985154134 scopus 로고
    • High pressure liquid chromatographic analysis of tyramine, phenylethylamine and tryptamine in sausage, cheese and chocolate
    • Koehler PE, Eitenmiller RR (1978) High pressure liquid chromatographic analysis of tyramine, phenylethylamine and tryptamine in sausage, cheese and chocolate. J Food Sci 43:1245-1247
    • (1978) J. Food Sci. , vol.43 , pp. 1245-1247
    • Koehler, P.E.1    Eitenmiller, R.R.2
  • 102
    • 0344927793 scopus 로고    scopus 로고
    • Metabolism of purine bases, nucleosides and alkaloids in theobromine-forming Theobroma cacao leaves
    • Koyama Y, Tomoda Y, Kato M et al (2003) Metabolism of purine bases, nucleosides and alkaloids in theobromine-forming Theobroma cacao leaves. Plant Physiol Biochem 41:977-984
    • (2003) Plant Physiol. Biochem. , vol.41 , pp. 977-984
    • Koyama, Y.1    Tomoda, Y.2    Kato, M.3
  • 103
    • 0026611868 scopus 로고
    • Behavioral evaluation of psycho-pharmacological and psychotoxic actions of methylxanthines by ambulatory activity and discrete avoidance in mice
    • Kuribara H, Asahi T, Tadokoro S (1992) Behavioral evaluation of psycho-pharmacological and psychotoxic actions of methylxanthines by ambulatory activity and discrete avoidance in mice. J Toxicol Sci 17:81-90
    • (1992) J. Toxicol. Sci. , vol.17 , pp. 81-90
    • Kuribara, H.1    Asahi, T.2    Tadokoro, S.3
  • 104
    • 0026636175 scopus 로고
    • Behavioral effects of cocoa and its main active compound theobromine: Evaluation by ambulatory activity and discrete avoidance in mice
    • Kuribara H, Tadokoro S (1992) Behavioral effects of cocoa and its main active compound theobromine: evaluation by ambulatory activity and discrete avoidance in mice. Jpn J Alcohol Drug Depend 27:168-179
    • (1992) Jpn. J. Alcohol. Drug Depend , vol.27 , pp. 168-179
    • Kuribara, H.1    Tadokoro, S.2
  • 106
    • 33646420331 scopus 로고    scopus 로고
    • Cocoa polyphenols inhibit phorbol ester-induced superoxide anion formation in cultured HL-60 cells and expression of cyclooxygenase-2 and activation of NF-kB and MAPKs in mouse skin in vivo
    • Lee KW, Kundu JK, Kim SO et al (2006) Cocoa polyphenols inhibit phorbol ester-induced superoxide anion formation in cultured HL-60 cells and expression of cyclooxygenase-2 and activation of NF-kB and MAPKs in mouse skin in vivo. J Nutr 136:1150-1155
    • (2006) J. Nutr. , vol.136 , pp. 1150-1155
    • Lee, K.W.1    Kundu, J.K.2    Kim, S.O.3
  • 107
    • 0023025836 scopus 로고
    • Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine and theophylline in man
    • Lelo A, Birkett DJ, Robson RA et al (1986) Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine and theophylline in man. Br J Clin Pharmacol 22:177-182
    • (1986) Br. J. Clin. Pharmacol. , vol.22 , pp. 177-182
    • Lelo, A.1    Birkett, D.J.2    Robson, R.A.3
  • 110
    • 58149178692 scopus 로고    scopus 로고
    • Beta blockers for asthma: A double-edged sword
    • Lipworth BJ, Williamson PA (2009) Beta blockers for asthma: a double-edged sword. Lancet 373:104-105
    • (2009) Lancet , vol.373 , pp. 104-105
    • Lipworth, B.J.1    Williamson, P.A.2
  • 111
    • 0034402564 scopus 로고    scopus 로고
    • Concentrations of caffeine, theophylline and theobromine in plasma and urine of dogs after application of coffee, tea and chocolate and its relevance to doping
    • Loeffler B, Kluge K, Ungemach FR et al (2000) [Concentrations of caffeine, theophylline and theobromine in plasma and urine of dogs after application of coffee, tea and chocolate and its relevance to doping]. Tierärztl Prax (K) 28:79-85
    • (2000) Tierärztl Prax (K) , vol.28 , pp. 79-85
    • Loeffler, B.1    Kluge, K.2    Ungemach, F.R.3
  • 112
    • 0020512418 scopus 로고
    • A novel bronchodilator xanthine apparently without adenosine receptor antagonism and tremorogenic effect
    • Lunell E, Svedmyr N, Andersson KE et al (1983) A novel bronchodilator xanthine apparently without adenosine receptor antagonism and tremorogenic effect. Eur J Respir Dis 64:333-339
    • (1983) Eur. J. Respir. Dis. , vol.64 , pp. 333-339
    • Lunell, E.1    Svedmyr, N.2    Andersson, K.E.3
  • 114
    • 0004218949 scopus 로고
    • MAFF UK, HMSO, London
    • MAFF UK (1988) Food portion sizes. HMSO, London
    • (1988) Food Portion Sizes
  • 115
    • 4744348990 scopus 로고    scopus 로고
    • Survey of caffeine and other methylxanthines in energy drinks and other caffeine-containing products (updated)
    • MAFF UK
    • MAFF UK (1998) Survey of caffeine and other methylxanthines in energy drinks and other caffeine-containing products (updated). Food surveillance information sheet 144
    • (1998) Food Surveillance Information Sheet , pp. 144
  • 116
    • 0014890923 scopus 로고
    • Interactions of monoamine oxidase inhibitors, amines, and foodstuffs
    • Marley E, Blackwell B (1970) Interactions of monoamine oxidase inhibitors, amines, and foodstuffs. Adv Pharmacol Chemother 8:185-239
    • (1970) Adv. Pharmacol. Chemother. , vol.8 , pp. 185-239
    • Marley, E.1    Blackwell, B.2
  • 117
    • 0027165567 scopus 로고
    • Caffeine, urinary calcium, calcium metabolism and bone
    • Massey LK, Whiting SJ (1993) Caffeine, urinary calcium, calcium metabolism and bone. J Nutr 123:1611-1614
    • (1993) J. Nutr. , vol.123 , pp. 1611-1614
    • Massey, L.K.1    Whiting, S.J.2
  • 119
  • 120
    • 0033801876 scopus 로고    scopus 로고
    • In vitro pharmacological activity of the tetrahydroisoquinoline salsolinol present in products from Theobroma cacao L. like cocoa and chocolate
    • Melzig MF, Putscher I, Henklein P et al (2000) In vitro pharmacological activity of the tetrahydroisoquinoline salsolinol present in products from Theobroma cacao L. like cocoa and chocolate. J Ethnopharmcol 73:153-159
    • (2000) J. Ethnopharmcol , vol.73 , pp. 153-159
    • Melzig, M.F.1    Putscher, I.2    Henklein, P.3
  • 121
    • 34547178922 scopus 로고    scopus 로고
    • Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells
    • Merighi S, Benini A, Mirandola P et al (2007) Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells. Mol Pharmacol 72:395-406
    • (2007) Mol. Pharmacol. , vol.72 , pp. 395-406
    • Merighi, S.1    Benini, A.2    Mirandola, P.3
  • 122
    • 0027992410 scopus 로고
    • Pharmacological versus sensory factors in the satiation of chocolate craving
    • Michener W, Rozin P (1994) Pharmacological versus sensory factors in the satiation of chocolate craving. Physiol Behav 56:419-422
    • (1994) Physiol. Behav. , vol.56 , pp. 419-422
    • Michener, W.1    Rozin, P.2
  • 123
    • 0021261818 scopus 로고
    • Comparative theobromine metabolism in five mammalian species
    • Miller GE, Radulovic LL, Dewit RH et al (1984) Comparative theobromine metabolism in five mammalian species. Drug Metab Dispos 12:154-160
    • (1984) Drug Metab. Dispos , vol.12 , pp. 154-160
    • Miller, G.E.1    Radulovic, L.L.2    Dewit, R.H.3
  • 125
    • 0022380439 scopus 로고
    • Influence of cimetidine, sulfinpyrazone, and cigarette smoking on theobromine metabolism in man
    • Miners JO, Attwood J, Wing LM et al (1985) Influence of cimetidine, sulfinpyrazone, and cigarette smoking on theobromine metabolism in man. Drug Metab Dispos 13:598-601
    • (1985) Drug Metab. Dispos , vol.13 , pp. 598-601
    • Miners, J.O.1    Attwood, J.2    Wing, L.M.3
  • 126
    • 0030474228 scopus 로고    scopus 로고
    • Absorption rate of methylxanthines following capsules, cola and chocolate
    • Mumford GK, Benowitz NL, Evans SM et al (1996) Absorption rate of methylxanthines following capsules, cola and chocolate. Eur J Clin Pharmacol 51:319-325
    • (1996) Eur. J. Clin. Pharmacol. , vol.51 , pp. 319-325
    • Mumford, G.K.1    Benowitz, N.L.2    Evans, S.M.3
  • 127
    • 0028341324 scopus 로고
    • Discriminative stimulus and subjective effects of theobromine and caffeine in humans
    • Mumford GK, Evans SM, Kaminski BJ et al (1994) Discriminative stimulus and subjective effects of theobromine and caffeine in humans. Psychopharmacology 115:1-8
    • (1994) Psychopharmacology , vol.115 , pp. 1-8
    • Mumford, G.K.1    Evans, S.M.2    Kaminski, B.J.3
  • 128
    • 0026048166 scopus 로고
    • Qualitative differences in the discriminative stimulus effects of low and high doses of caffeine in the rat
    • Mumford GK, Holtzman G (1991) Qualitative differences in the discriminative stimulus effects of low and high doses of caffeine in the rat. J Pharmacol Exp Ther 258:857-865
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 857-865
    • Mumford, G.K.1    Holtzman, G.2
  • 129
    • 0024970497 scopus 로고
    • Isoquinolines, beta-carbolines and alcohol drinking: Involvement of opioid and dopaminergic mechanisms
    • Myers RD (1989) Isoquinolines, beta-carbolines and alcohol drinking: involvement of opioid and dopaminergic mechanisms. Experientia 45:436-443
    • (1989) Experientia , vol.45 , pp. 436-443
    • Myers, R.D.1
  • 130
    • 0021495887 scopus 로고
    • Nutrition and dental decay
    • Naylor MN (1984) Nutrition and dental decay. Proc Nutr Soc 43:257-263
    • (1984) Proc. Nutr. Soc. , vol.43 , pp. 257-263
    • Naylor, M.N.1
  • 132
    • 67649213864 scopus 로고    scopus 로고
    • Toxicity of fluoride to microorganisms in biological wastewater treatment systems
    • Ochoa-Herrera V, Banihani Q, León G et al (2009) Toxicity of fluoride to microorganisms in biological wastewater treatment systems. Water Res 43:3177-3186
    • (2009) Water Res. , vol.43 , pp. 3177-3186
    • Ochoa-Herrera, V.1    Banihani, Q.2    León, G.3
  • 134
    • 0023746424 scopus 로고
    • Coffee drinking and prevalence of bronchial asthma
    • Pagano R, Negri E, Decarli A et al (1988) Coffee drinking and prevalence of bronchial asthma. Chest 94:386-389
    • (1988) Chest , vol.94 , pp. 386-389
    • Pagano, R.1    Negri, E.2    Decarli, A.3
  • 136
    • 0141992217 scopus 로고    scopus 로고
    • Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation
    • Patel HJ, Birrell MA, Crispino N et al (2003) Inhibition of guinea-pig and human sensory nerve activity and the cough reflex in guinea-pigs by cannabinoid (CB2) receptor activation. Br J Pharmacol 140:261-268
    • (2003) Br. J. Pharmacol. , vol.140 , pp. 261-268
    • Patel, H.J.1    Birrell, M.A.2    Crispino, N.3
  • 137
    • 0025647353 scopus 로고
    • 2-Phenylethylamine: A modulator of catecholamine transmission in the mammalian central nervous system?
    • Paterson IA, Juorio AV, Boulton AA (1990) 2-Phenylethylamine: a modulator of catecholamine transmission in the mammalian central nervous system? J Neurochem 55:1827-1837
    • (1990) J. Neurochem. , vol.55 , pp. 1827-1837
    • Paterson, I.A.1    Juorio, A.V.2    Boulton, A.A.3
  • 138
    • 33746442025 scopus 로고    scopus 로고
    • The effect of cocoa polyphenols on the growth, metabolism and biofilm formation by Streptococcus mutans and Streptococcus sanguinis
    • Percival RS, Devine DA, Duggal MS et al (2006) The effect of cocoa polyphenols on the growth, metabolism and biofilm formation by Streptococcus mutans and Streptococcus sanguinis. Eur J Oral Sci 114:343-348
    • (2006) Eur. J. Oral. Sci. , vol.114 , pp. 343-348
    • Percival, R.S.1    Devine, D.A.2    Duggal, M.S.3
  • 140
    • 0037174390 scopus 로고    scopus 로고
    • Investigation of the tuber constituents of maca (Lepidium meyenii Walp.)
    • Piacente S, Carbone V, Plaza A et al (2002) Investigation of the tuber constituents of maca (Lepidium meyenii Walp.). J Agric Food Chem 50:5621-5625
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 5621-5625
    • Piacente, S.1    Carbone, V.2    Plaza, A.3
  • 141
    • 18844448134 scopus 로고    scopus 로고
    • The role of acetaldehyde in the neurobehavioral effects of ethanol: A comprehensive review of animal studies
    • Quertemont E, Tambour S, Tirelli E (2005) The role of acetaldehyde in the neurobehavioral effects of ethanol: a comprehensive review of animal studies. Prog Neurobiol 75:247-274
    • (2005) Prog. Neurobiol. , vol.75 , pp. 247-274
    • Quertemont, E.1    Tambour, S.2    Tirelli, E.3
  • 142
    • 0004569208 scopus 로고
    • Central nervous system stimulants [continued]: The xanthines
    • Goodman Gilman A, Goodman LS, Gilman A eds, 6th edn. Macmillan, New York
    • Rall TW (1980) Central nervous system stimulants [continued]: the xanthines. In: Goodman Gilman A, Goodman LS, Gilman A (eds) The pharmacological basis of therapeutics, 6th edn. Macmillan, New York
    • (1980) The Pharmacological Basis of Therapeutics
    • Rall, T.W.1
  • 143
    • 53849125889 scopus 로고    scopus 로고
    • The contribution of cocoa additive to cigarette smoking addiction
    • Bilthoven
    • Rambali B, Van Andel I, Schenk E et al (2002) The contribution of cocoa additive to cigarette smoking addiction. RIVM, Bilthoven
    • (2002) RIVM
    • Rambali, B.1    Van Andel, I.2    Schenk, E.3
  • 146
    • 33845982155 scopus 로고    scopus 로고
    • Adenosine A1 receptors determine effects of caffeine on total fluid intake but not caffeine appetite
    • Rieg T, Schnermann J, Vallon V (2007) Adenosine A1 receptors determine effects of caffeine on total fluid intake but not caffeine appetite. Eur J Pharmacol 555:174-177
    • (2007) Eur. J. Pharmacol. , vol.555 , pp. 174-177
    • Rieg, T.1    Schnermann, J.2    Vallon, V.3
  • 147
    • 56549130766 scopus 로고    scopus 로고
    • Simultaneous determination of theobromine, (+)-catechin, caffeine, and (-)-epicatechin in standard reference material baking chocolate 2384, cocoa, cocoa beans, and cocoa butter
    • Risner CH (2008) Simultaneous determination of theobromine, (+)-catechin, caffeine, and (-)-epicatechin in standard reference material baking chocolate 2384, cocoa, cocoa beans, and cocoa butter. J Chromatogr Sci 46:892-899
    • (2008) J. Chromatogr. Sci. , vol.46 , pp. 892-899
    • Risner, C.H.1
  • 149
    • 0026285162 scopus 로고
    • Food cravings in relation to body mass index, restraint and estradiol levels: A repeated measures study in healthy women
    • Rodin J, Mancuso J, Granger J et al (1991) Food cravings in relation to body mass index, restraint and estradiol levels: a repeated measures study in healthy women. Appetite 17:177-185
    • (1991) Appetite , vol.17 , pp. 177-185
    • Rodin, J.1    Mancuso, J.2    Granger, J.3
  • 150
    • 84976097138 scopus 로고
    • Food, mood and appetite
    • Rogers PJ (1995) Food, mood and appetite. Nutr Res Rev 8:243-269
    • (1995) Nutr. Res. Rev. , vol.8 , pp. 243-269
    • Rogers, P.J.1
  • 151
    • 0031863374 scopus 로고    scopus 로고
    • Regular caffeine consumption: A balance of adverse and beneficial effects for mood and psychomotor performance
    • Rogers PJ, Dernoncourt C (1998) Regular caffeine consumption: a balance of adverse and beneficial effects for mood and psychomotor performance. Pharmacol Biochem Behav 59:1039-1045
    • (1998) Pharmacol. Biochem. Behav. , vol.59 , pp. 1039-1045
    • Rogers, P.J.1    Dernoncourt, C.2
  • 152
    • 0029087503 scopus 로고
    • Overnight caffeine abstinence and negative reinforcement of preference for caffeine-containing drinks
    • Rogers PJ, Richardson NJ, Elliman NA (1995) Overnight caffeine abstinence and negative reinforcement of preference for caffeine-containing drinks. Psychopharmacology 120:457-462
    • (1995) Psychopharmacology , vol.120 , pp. 457-462
    • Rogers, P.J.1    Richardson, N.J.2    Elliman, N.A.3
  • 153
    • 0034027751 scopus 로고    scopus 로고
    • Food craving and food "addiction": A critical review of the evidence from a biopsychosocial perspective
    • Rogers PJ, Smit HJ (2000) Food craving and food "addiction": A critical review of the evidence from a biopsychosocial perspective. Pharmacol Biochem Behav 66:3-14
    • (2000) Pharmacol. Biochem. Behav. , vol.66 , pp. 3-14
    • Rogers, P.J.1    Smit, H.J.2
  • 154
    • 0026307598 scopus 로고
    • Chocolate craving and liking
    • Rozin P, Levine E, Stoess C (1991) Chocolate craving and liking. Appetite 17:199-212
    • (1991) Appetite , vol.17 , pp. 199-212
    • Rozin, P.1    Levine, E.2    Stoess, C.3
  • 155
    • 33846407222 scopus 로고    scopus 로고
    • Role of adenosine receptors in the regulation of angiogenic factors and neovascularization in hypoxia
    • Ryzhov S, McCaleb JL, Goldstein AE et al (2007) Role of adenosine receptors in the regulation of angiogenic factors and neovascularization in hypoxia. J Pharmacol Exp Ther 320:565-572
    • (2007) J. Pharmacol. Exp. Ther. , vol.320 , pp. 565-572
    • Ryzhov, S.1    McCaleb, J.L.2    Goldstein, A.E.3
  • 156
    • 50949115838 scopus 로고    scopus 로고
    • Host A (2B) adenosine receptors promote carcinoma growth
    • Ryzhov S, Novitskiy SV, Zaynagetdinov R et al (2008) Host A (2B) adenosine receptors promote carcinoma growth. Neoplasia 10:987-995
    • (2008) Neoplasia , vol.10 , pp. 987-995
    • Ryzhov, S.1    Novitskiy, S.V.2    Zaynagetdinov, R.3
  • 158
    • 0028556677 scopus 로고
    • Determination of xanthines by highperformance liquid chromatography and thin-layer chromatography in horse urine after ingestion of guaraná powder
    • Salvadori MC, Rieser EM, Ribeiro Neto LM et al (1994) Determination of xanthines by highperformance liquid chromatography and thin-layer chromatography in horse urine after ingestion of guaraná powder. Analyst 119:2701-2703
    • (1994) Analyst , vol.119 , pp. 2701-2703
    • Salvadori, M.C.1    Rieser, E.M.2    Ribeiro Neto, L.M.3
  • 159
    • 0016319837 scopus 로고
    • A phenylethylamine oxidising defect in migraine
    • Sandler M, Youdim M B H, Hanington E (1974) A phenylethylamine oxidising defect in migraine. Nature 250:335-337
    • (1974) Nature , vol.250 , pp. 335-337
    • Sandler, M.1    Youdim, M.B.H.2    Hanington, E.3
  • 160
    • 0033199892 scopus 로고    scopus 로고
    • Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
    • Sarkaria JN, Busby EC, Tibbetts RS et al (1999) Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res 59:4375-4382
    • (1999) Cancer Res. , vol.59 , pp. 4375-4382
    • Sarkaria, J.N.1    Busby, E.C.2    Tibbetts, R.S.3
  • 161
    • 33845660012 scopus 로고    scopus 로고
    • The effects of male age on sperm DNA damage in healthy non-smokers
    • Schmid TE, Eskenazi B, Baumgartner A et al (2007) The effects of male age on sperm DNA damage in healthy non-smokers. Hum Reprod 22:180-187
    • (2007) Hum. Reprod. , vol.22 , pp. 180-187
    • Schmid, T.E.1    Eskenazi, B.2    Baumgartner, A.3
  • 162
    • 0024589887 scopus 로고
    • Cardiovascular consequences of magnesium deficiency and loss: Pathogenesis, prevalence and manifestations - Magnesium and chloride loss in refractory potassium repletion
    • Seelig M (1989) Cardiovascular consequences of magnesium deficiency and loss: pathogenesis, prevalence and manifestations - magnesium and chloride loss in refractory potassium repletion. Am J Cardiol 63:4G-21G
    • (1989) Am. J. Cardiol. , vol.63
    • Seelig, M.1
  • 163
    • 0020549822 scopus 로고
    • Theobromine metabolism and pharmacokinetics in pregnant and nonpregnant Sprague-Dawley rats
    • Shively CA, Tarka SM Jr (1983) Theobromine metabolism and pharmacokinetics in pregnant and nonpregnant Sprague-Dawley rats. Toxicol Appl Pharmacol 67:376-382
    • (1983) Toxicol. Appl. Pharmacol. , vol.67 , pp. 376-382
    • Shively, C.A.1    Tarka Jr., S.M.2
  • 164
    • 84966823005 scopus 로고
    • PIHKAL: A chemical love story
    • Berkeley
    • Shulgin A, Shulgin A (1991) PIHKAL: a chemical love story. Transform, Berkeley
    • (1991) Transform
    • Shulgin, A.1    Shulgin, A.2
  • 165
    • 0022181291 scopus 로고
    • The bronchodilator effect and pharmacokinetics of theobromine in young patients with asthma
    • Simons F E R, Becker AB, Simons KJ et al (1985) The bronchodilator effect and pharmacokinetics of theobromine in young patients with asthma. J Allergy Clin Immunol 76:703-707
    • (1985) J. Allergy Clin. Immunol. , vol.76 , pp. 703-707
    • Simons, F.E.R.1    Becker, A.B.2    Simons, K.J.3
  • 166
    • 33746508537 scopus 로고    scopus 로고
    • Chocolate feeding of pregnant mice resulted in epigallocatechin-related embryonic angiogenesis suppression and bone mineralization disorder
    • Skopinski P, Skopinska-Rózewska E, Kaminski A et al (2004) Chocolate feeding of pregnant mice resulted in epigallocatechin-related embryonic angiogenesis suppression and bone mineralization disorder. Pol J Vet Sci 7:131-133
    • (2004) Pol. J. Vet. Sci. , vol.7 , pp. 131-133
    • Skopinski, P.1    Skopinska-Rózewska, E.2    Kaminski, A.3
  • 167
    • 0027717516 scopus 로고
    • Smoking, alcohol, coffee, tea, caffeine, and theobromine: Risk of prostate cancer in Utah (United States)
    • Slattery ML, West DW (1993) Smoking, alcohol, coffee, tea, caffeine, and theobromine: risk of prostate cancer in Utah (United States). Cancer Causes Control 4:559-563
    • (1993) Cancer Causes Control , vol.4 , pp. 559-563
    • Slattery, M.L.1    West, D.W.2
  • 168
    • 26644460431 scopus 로고    scopus 로고
    • Reinforcing effects of caffeine and theobromine as found in chocolate
    • Smit HJ, Blackburn RJ (2005) Reinforcing effects of caffeine and theobromine as found in chocolate. Psychopharmacology 181:101-106
    • (2005) Psychopharmacology , vol.181 , pp. 101-106
    • Smit, H.J.1    Blackburn, R.J.2
  • 169
    • 10944238660 scopus 로고    scopus 로고
    • Methylxanthines are the psycho-pharmacologically active constituents of chocolate
    • Smit HJ, Gaffan EA, Rogers PJ (2004) Methylxanthines are the psycho-pharmacologically active constituents of chocolate. Psychopharmacology 176:412-419
    • (2004) Psychopharmacology , vol.176 , pp. 412-419
    • Smit, H.J.1    Gaffan, E.A.2    Rogers, P.J.3
  • 170
    • 0033770879 scopus 로고    scopus 로고
    • Effects of low doses of caffeine on cognitive performance, mood and thirst in low and higher caffeine consumers
    • Smit HJ, Rogers PJ (2000) Effects of low doses of caffeine on cognitive performance, mood and thirst in low and higher caffeine consumers. Psychopharmacology 152:167-173
    • (2000) Psychopharmacology , vol.152 , pp. 167-173
    • Smit, H.J.1    Rogers, P.J.2
  • 171
    • 10944234136 scopus 로고    scopus 로고
    • Potentially psychoactive constituents of cocoa-containing products
    • Hetherington MM ed, Leatherhead Food RA Publishing, Leatherhead
    • Smit HJ, Rogers PJ (2001) Potentially psychoactive constituents of cocoa-containing products. In: Hetherington MM (ed) Food cravings and addiction. Leatherhead Food RA Publishing, Leatherhead
    • (2001) Food Cravings and Addiction
    • Smit, H.J.1    Rogers, P.J.2
  • 172
    • 77957594570 scopus 로고    scopus 로고
    • Effects of caffeine on mood
    • Smith BD, Gupta U, Gupta BS eds, CRC, Boca Raton
    • Smit HJ, Rogers PJ (2007) Effects of caffeine on mood. In: Smith BD, Gupta U, Gupta BS (eds) Caffeine and activation theory. CRC, Boca Raton
    • (2007) Caffeine and Activation Theory
    • Smit, H.J.1    Rogers, P.J.2
  • 173
    • 0019432588 scopus 로고
    • Amines in food
    • Smith TA (1981) Amines in food. Food Chem 6:169-200
    • (1981) Food Chem. , vol.6 , pp. 169-200
    • Smith, T.A.1
  • 174
    • 0001441518 scopus 로고
    • Adenosine receptors and behavioral actions of methylxanthines
    • Snyder SH, Katims JJ, Annau Z et al (1981) Adenosine receptors and behavioral actions of methylxanthines. Proc Natl Acad Sci USA 78:3260-3264
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 3260-3264
    • Snyder, S.H.1    Katims, J.J.2    Annau, Z.3
  • 175
    • 0024532582 scopus 로고
    • Toxic effects of theobromine on mature and immature male rabbits
    • Soffietti MG, Nebbia C, Valenza F et al (1989) Toxic effects of theobromine on mature and immature male rabbits. J Comp Pathol 100:47-58
    • (1989) J. Comp. Pathol. , vol.100 , pp. 47-58
    • Soffietti, M.G.1    Nebbia, C.2    Valenza, F.3
  • 178
    • 0017391612 scopus 로고
    • The influence of caffeine and theobromine on locomotive activity and the brain cGMP/cAMP ratio in white mice
    • Sprugel W, Mitznegg P, Heim F (1977) The influence of caffeine and theobromine on locomotive activity and the brain cGMP/cAMP ratio in white mice. Biochem Pharmacol 26:1723-1724
    • (1977) Biochem. Pharmacol. , vol.26 , pp. 1723-1724
    • Sprugel, W.1    Mitznegg, P.2    Heim, F.3
  • 179
    • 46949104414 scopus 로고    scopus 로고
    • Chocolate mouth rinse: Effect on plaque accumulation and mutans streptococci counts when used by children
    • Srikanth RK, Shashikiran ND, Subba Reddy VV (2008) Chocolate mouth rinse: effect on plaque accumulation and mutans streptococci counts when used by children. J Indian Soc Pedod Prev Dent 26:67-70
    • (2008) J. Indian Soc. Pedod Prev. Dent. , vol.26 , pp. 67-70
    • Srikanth, R.K.1    Shashikiran, N.D.2    Subba Reddy, V.V.3
  • 180
    • 0004010458 scopus 로고
    • The Williams & Wilkins Company, Baltimore
    • Stedman's Medical Dictionary (1976). The Williams & Wilkins Company, Baltimore
    • (1976) Stedman's Medical Dictionary
  • 181
    • 0028349014 scopus 로고
    • Tryptophan in the treatment of late luteal phase dyphoric disorder: A pilot study
    • Steinberg S, Annable L, Young SN et al (1986) Tryptophan in the treatment of late luteal phase dyphoric disorder: a pilot study. J Psychiatry Neurosci 19:114-119
    • (1986) J. Psychiatry Neurosci. , vol.19 , pp. 114-119
    • Steinberg, S.1    Annable, L.2    Young, S.N.3
  • 183
    • 0028349390 scopus 로고
    • Theobromine poisoning in dogs
    • Strachan ER, Bennett A (1994) Theobromine poisoning in dogs. Vet Rec 134:284
    • (1994) Vet. Rec. , vol.134 , pp. 284
    • Strachan, E.R.1    Bennett, A.2
  • 184
    • 0014065952 scopus 로고
    • Effect on hamster caries by purine derivatives vanillin and some tannincontaining materials
    • Strålfors A (1967) Effect on hamster caries by purine derivatives vanillin and some tannincontaining materials. Arch Oral Biol 12:321-332
    • (1967) Arch. Oral. Biol. , vol.12 , pp. 321-332
    • Strålfors, A.1
  • 185
    • 0020216530 scopus 로고
    • The toxicology of cocoa and methylxanthines: A review of the literature
    • Tarka SM Jr (1982) The toxicology of cocoa and methylxanthines: a review of the literature. CRC Crit Rev Toxicol 9:275-312
    • (1982) CRC Crit. Rev. Toxicol. , vol.9 , pp. 275-312
    • Tarka Jr., S.M.1
  • 186
    • 0022921095 scopus 로고
    • Evaluation of the perinatal, postnatal and teratogenic effects of cocoa powder and theobromine in Sprague-Dawley/CD rats
    • Tarka SM Jr, Applebaum RS, Borzelleca JF (1986a) Evaluation of the perinatal, postnatal and teratogenic effects of cocoa powder and theobromine in Sprague-Dawley/CD rats. Food Chem Toxicol 24:375-382
    • (1986) Food Chem. Toxicol. , vol.24 , pp. 375-382
    • Tarka Jr., S.M.1    Applebaum, R.S.2    Borzelleca, J.F.3
  • 187
    • 0022922278 scopus 로고
    • Evaluation of the teratogenic potential of cocoa powder and theobromine in New Zealand white rabbits
    • Tarka SM Jr, Applebaum RS, Borzelleca JF (1986b) Evaluation of the teratogenic potential of cocoa powder and theobromine in New Zealand white rabbits. Food Chem Toxicol 24:363-374
    • (1986) Food Chem. Toxicol. , vol.24 , pp. 363-374
    • Tarka Jr., S.M.1    Applebaum, R.S.2    Borzelleca, J.F.3
  • 188
    • 0026021359 scopus 로고
    • Chronic toxicity/carcinogenicity studies of cocoa powder in rats
    • Tarka SM Jr, Morrissey RB, Apgar JL et al (1991) Chronic toxicity/carcinogenicity studies of cocoa powder in rats. Food Chem Toxicol 29:7-19
    • (1991) Food Chem. Toxicol. , vol.29 , pp. 7-19
    • Tarka Jr., S.M.1    Morrissey, R.B.2    Apgar, J.L.3
  • 189
    • 0018765740 scopus 로고
    • Short-term effects of graded levels of theobromine in laboratory rodents
    • Tarka SM Jr, Zoumas BL, Gans JH (1979) Short-term effects of graded levels of theobromine in laboratory rodents. Toxicol Appl Pharmacol 49:127-149
    • (1979) Toxicol. Appl. Pharmacol. , vol.49 , pp. 127-149
    • Tarka Jr., S.M.1    Zoumas, B.L.2    Gans, J.H.3
  • 190
    • 0019422643 scopus 로고
    • Effects of continuous administration of dietary theobromine on rat testicular weight and morphology
    • Tarka SM Jr, Zoumas BL, Gans JH (1981) Effects of continuous administration of dietary theobromine on rat testicular weight and morphology. Toxicol Appl Pharmacol 58:76-82
    • (1981) Toxicol. Appl. Pharmacol. , vol.58 , pp. 76-82
    • Tarka Jr., S.M.1    Zoumas, B.L.2    Gans, J.H.3
  • 191
    • 0041920912 scopus 로고    scopus 로고
    • Chocolate and blood pressure in elderly individuals with isolated systolic hypertension
    • Taubert D, Berkels R, Roesen R et al (2003) Chocolate and blood pressure in elderly individuals with isolated systolic hypertension. JAMA 290:1029-1030
    • (2003) JAMA , vol.290 , pp. 1029-1030
    • Taubert, D.1    Berkels, R.2    Roesen, R.3
  • 192
    • 0025045668 scopus 로고
    • Occurrence and formation of biologically active amines in foods
    • ten Brink B, Damink C, Joosten J M L J et al (1990) Occurrence and formation of biologically active amines in foods. Int J Food Microbiol 11:73-84
    • (1990) Int. J. Food Microbiol. , vol.11 , pp. 73-84
    • Brink, B.T.1    Damink, C.2    Joosten, J.M.L.J.3
  • 193
    • 70449345550 scopus 로고    scopus 로고
    • Merck & Co Inc., Whitehouse Station, NJ
    • The Merck Index (2006). Merck & Co Inc., Whitehouse Station, NJ
    • (2006) The Merck Index
  • 194
    • 77957558886 scopus 로고
    • On the rise and development of synthetical chemistry
    • Thorpe TE (1893) On the rise and development of synthetical chemistry. Fortn Rev 53:691-701
    • (1893) Fortn Rev. , vol.53 , pp. 691-701
    • Thorpe, T.E.1
  • 195
    • 84985092595 scopus 로고
    • Application of high-pressure liquid chromatography to the study of variables affecting theobromine and caffeine concentrations in cocoa beans
    • Timbie DJ, Sechrist L, Keeney PG (1978) Application of high-pressure liquid chromatography to the study of variables affecting theobromine and caffeine concentrations in cocoa beans. J Food Sci 43 (560-562): 565
    • (1978) J. Food Sci. , vol.43 , Issue.560-562 , pp. 565
    • Timbie, D.J.1    Sechrist, L.2    Keeney, P.G.3
  • 196
    • 0034129652 scopus 로고    scopus 로고
    • Cannabinoid mimics in chocolate utilized as an argument in court
    • Tytgat J, Mv B, Daenens P (2000) Cannabinoid mimics in chocolate utilized as an argument in court. Int J Legal Med 113:137-139
    • (2000) Int. J. Legal Med. , vol.113 , pp. 137-139
    • Tytgat, J.1    Mv, B.2    Daenens, P.3
  • 197
    • 13244257156 scopus 로고    scopus 로고
    • Theobromine inhibits sensory nerve activation and cough
    • Usmani OS, Belvisi MG, Patel HJ et al (2005) Theobromine inhibits sensory nerve activation and cough. FASEB J 19:231-233
    • (2005) FASEB J. , vol.19 , pp. 231-233
    • Usmani, O.S.1    Belvisi, M.G.2    Patel, H.J.3
  • 199
    • 42749086454 scopus 로고    scopus 로고
    • Comparative diffusion of drugs through bronchial tissue
    • van Zyl JM, Derendinger B, Seifart HI et al (2008) Comparative diffusion of drugs through bronchial tissue. Int J Pharm 357:32-36
    • (2008) Int. J. Pharm. , vol.357 , pp. 32-36
    • Van Zyl, J.M.1    Derendinger, B.2    Seifart, H.I.3
  • 200
    • 0034032155 scopus 로고    scopus 로고
    • The symptoms of advanced cancer: Relationship to age, gender, and performance status in 1, 000 patients
    • Walsh D, Donnelly S, Rybicki L (2000) The symptoms of advanced cancer: relationship to age, gender, and performance status in 1, 000 patients. Support Care Cancer 8:175-179
    • (2000) Support Care Cancer , vol.8 , pp. 175-179
    • Walsh, D.1    Donnelly, S.2    Rybicki, L.3
  • 201
    • 36348950847 scopus 로고    scopus 로고
    • Study on the increase mechanism of the caffeine content during the fermentation of tea with microorganisms
    • Wang X, Wan X, Hu S et al (2008) Study on the increase mechanism of the caffeine content during the fermentation of tea with microorganisms. Food Chem 107:1086-1091
    • (2008) Food Chem. , vol.107 , pp. 1086-1091
    • Wang, X.1    Wan, X.2    Hu, S.3
  • 202
    • 0028009684 scopus 로고
    • Theobromine toxicity on Sertoli cells and comparison with cocoa extract in male rats
    • Wang Y, Waller DP (1994) Theobromine toxicity on Sertoli cells and comparison with cocoa extract in male rats. Toxicol Lett 70:155-164
    • (1994) Toxicol. Lett. , vol.70 , pp. 155-164
    • Wang, Y.1    Waller, D.P.2
  • 203
    • 0026456820 scopus 로고
    • Reproductive toxicity of theobromine and cocoa extract in male rats
    • Wang Y, Waller DP, Hikim AP et al (1992) Reproductive toxicity of theobromine and cocoa extract in male rats. Reprod Toxicol 6:347-353
    • (1992) Reprod. Toxicol. , vol.6 , pp. 347-353
    • Wang, Y.1    Waller, D.P.2    Hikim, A.P.3
  • 204
    • 0033897673 scopus 로고    scopus 로고
    • The pharmacokinetics, metabolism and urinary detection time of caffeine in camels
    • Wasfi IA, Boni NS, Elghazali M et al (2000) The pharmacokinetics, metabolism and urinary detection time of caffeine in camels. Res Vet Sci 69:69-74
    • (2000) Res. Vet. Sci. , vol.69 , pp. 69-74
    • Wasfi, I.A.1    Boni, N.S.2    Elghazali, M.3
  • 205
    • 44449093481 scopus 로고    scopus 로고
    • Inhibitory effect of cocoa catechins on embryonic and tumor angiogenesis in mice
    • Wasiutynski A, Siwicki AK, Balan BJ et al (2005) Inhibitory effect of cocoa catechins on embryonic and tumor angiogenesis in mice. Pol J Environ Stud 14:800-805
    • (2005) Pol. J. Environ. Stud. , vol.14 , pp. 800-805
    • Wasiutynski, A.1    Siwicki, A.K.2    Balan, B.J.3
  • 207
    • 0018058206 scopus 로고
    • Testicular atrophy and impaired spermatogenesis in rats fed high levels of the methylxanthines caffeine, theobromine, or theophylline
    • Weinberger MA, Friedman L, Farber TM et al (1978) Testicular atrophy and impaired spermatogenesis in rats fed high levels of the methylxanthines caffeine, theobromine, or theophylline. J Environ Path Toxicol 1:669-688
    • (1978) J. Environ. Path Toxicol. , vol.1 , pp. 669-688
    • Weinberger, M.A.1    Friedman, L.2    Farber, T.M.3
  • 208
    • 0023837778 scopus 로고
    • Determination of methylxanthine stimulants in urine of racing greyhounds by high-performance liquid chromatography. Resolution of a contested drug administration case
    • Wells DJ, Hanks BM, Yarbrough CS et al (1988) Determination of methylxanthine stimulants in urine of racing greyhounds by high-performance liquid chromatography. Resolution of a contested drug administration case. J Anal Toxicol 12:30-32
    • (1988) J. Anal. Toxicol. , vol.12 , pp. 30-32
    • Wells, D.J.1    Hanks, B.M.2    Yarbrough, C.S.3
  • 209
    • 77957550640 scopus 로고    scopus 로고
    • World Anti-Doping Agency, Q&A: 2009 prohibited list, Accessed 8 Apr. 2010
    • World Anti-Doping Agency (2008) Q&A: 2009 prohibited list. http://www.fibt.com/fileadmin/Medical/2009-2010/QA-List-ORpdf. Accessed 8 Apr. 2010
    • (2008)
  • 210
    • 0024528524 scopus 로고
    • Carbohydrates and depression
    • Wurtman RJ, Wurtman JJ (1989) Carbohydrates and depression. Sci Am 260:68-75
    • (1989) Sci. Am. , vol.260 , pp. 68-75
    • Wurtman, R.J.1    Wurtman, J.J.2
  • 211
    • 33745956270 scopus 로고    scopus 로고
    • Simultaneous analysis of purine alkaloids and catechins in Camellia sinensis, Camellia ptilophylla and Camellia assamica var. kucha by HPLC
    • Yang XR, Ye CX, Xu JK et al (2007) Simultaneous analysis of purine alkaloids and catechins in Camellia sinensis, Camellia ptilophylla and Camellia assamica var. kucha by HPLC. Food Chem 100:1132-1136
    • (2007) Food Chem. , vol.100 , pp. 1132-1136
    • Yang, X.R.1    Ye, C.X.2    Xu, J.K.3
  • 212
    • 0031746166 scopus 로고    scopus 로고
    • Conditioned flavor preference negatively reinforced by caffeine in human volunteers
    • Yeomans MR, Spetch H, Rogers PJ (1998) Conditioned flavor preference negatively reinforced by caffeine in human volunteers. Psychopharmacology 137:401-409
    • (1998) Psychopharmacology , vol.137 , pp. 401-409
    • Yeomans, M.R.1    Spetch, H.2    Rogers, P.J.3
  • 214
    • 0027689454 scopus 로고
    • The use of diet and dietary components in the study of factors controlling affect in humans: A review
    • Young SN (1993) The use of diet and dietary components in the study of factors controlling affect in humans: a review. J Psychiatry Neurosci 18:235-244
    • (1993) J. Psychiatry Neurosci. , vol.18 , pp. 235-244
    • Young, S.N.1
  • 215
    • 0022842916 scopus 로고
    • The effect of altered tryptophan levels on mood and behavior in normal human males
    • Young SN, Pihl RO, Ervin FR (1986) The effect of altered tryptophan levels on mood and behavior in normal human males. Clin Neuropharmacol 9:516-518
    • (1986) Clin. Neuropharmacol. , vol.9 , pp. 516-518
    • Young, S.N.1    Pihl, R.O.2    Ervin, F.R.3
  • 216
    • 2342488670 scopus 로고    scopus 로고
    • Biosynthesis, accumulation and degradation of theobromine in developing Theobroma cacao fruits
    • Zheng X-Q, Koyama Y, Nagai C et al (2004) Biosynthesis, accumulation and degradation of theobromine in developing Theobroma cacao fruits. J Plant Physiol 161:363-369
    • (2004) J. Plant Physiol. , vol.161 , pp. 363-369
    • Zheng, X.-Q.1    Koyama, Y.2    Nagai, C.3
  • 217
    • 0026926589 scopus 로고
    • Vorkommen von beta-Phenylethylamin und seinen Derivaten in Kakao und Kakaoerzeugnissen
    • Ziegleder G, Stojacic E, Stumpf B (1992) Vorkommen von beta-Phenylethylamin und seinen Derivaten in Kakao und Kakaoerzeugnissen. Z Lebensm Unters Forsch 195:235-238
    • (1992) Z. Lebensm Unters Forsch , vol.195 , pp. 235-238
    • Ziegleder, G.1    Stojacic, E.2    Stumpf, B.3


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