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Volumn 77, Issue 10, 2010, Pages 962-970

Proinflammatory activation pattern of human umbilical vein endothelial cells induced by IL-1β, TNF-α, and LPS

Author keywords

Endothelial cells; Inflammation; Lipopolysaccharide; Signal transduction

Indexed keywords

AUTACOID; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA;

EID: 77957280402     PISSN: 15524922     EISSN: 15524930     Source Type: Journal    
DOI: 10.1002/cyto.a.20952     Document Type: Article
Times cited : (141)

References (49)
  • 1
    • 0037389936 scopus 로고    scopus 로고
    • Bench-to-bedside review: Endothelial cell dysfunction in severe sepsis: A role in organ dysfunction?
    • Vallet B. Bench-to-bedside review: Endothelial cell dysfunction in severe sepsis: a role in organ dysfunction? Crit Care 2003;7:130-138.
    • (2003) Crit Care , vol.7 , pp. 130-138
    • Vallet, B.1
  • 2
    • 0036174408 scopus 로고    scopus 로고
    • Pathways for bradykinin formation and inflammatory disease
    • Kaplan AP, Joseph K, Silverberg M. Pathways for bradykinin formation and inflammatory disease. J Allergy Clin Immunol 2002;109:195-209.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 195-209
    • Kaplan, A.P.1    Joseph, K.2    Silverberg, M.3
  • 3
    • 0030005626 scopus 로고    scopus 로고
    • Role of endothelium in thrombosis and hemostasis
    • Wu KK, Thiagarajan P. Role of endothelium in thrombosis and hemostasis. Annu Rev Med 1996;47:315-331.
    • (1996) Annu Rev Med , vol.47 , pp. 315-331
    • Wu, K.K.1    Thiagarajan, P.2
  • 4
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 1993;362:801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 5
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-An inflammatory disease
    • Ross R. Atherosclerosis-An inflammatory disease. N Engl J Med 1999;340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 6
    • 0034566561 scopus 로고    scopus 로고
    • Microcirculatory dysfunction in chronic venous insufficiency (CVI)
    • Junger M, Steins A, Hahn M, Hafner HM. Microcirculatory dysfunction in chronic venous insufficiency (CVI). Microcirculation 2000;7:S3-S12.
    • (2000) Microcirculation , vol.7
    • Junger, M.1    Steins, A.2    Hahn, M.3    Hafner, H.M.4
  • 7
    • 0037308613 scopus 로고    scopus 로고
    • The effects of proinflammatory cytokines on cytokine-chemokine gene expression profiles in the human corneal endothelium
    • Yamagami H, Yamagami S, Inoki T, Amano S, Miyata K. The effects of proinflammatory cytokines on cytokine-chemokine gene expression profiles in the human corneal endothelium. Invest Ophthalmol Vis Sci 2003;44:514-520.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 514-520
    • Yamagami, H.1    Yamagami, S.2    Inoki, T.3    Amano, S.4    Miyata, K.5
  • 8
    • 0036775020 scopus 로고    scopus 로고
    • TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS
    • Zeuke S, Ulmer AJ, Kusumoto S, Katus HA, Heine H. TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS. Cardiovasc Res 2002;56:126-134.
    • (2002) Cardiovasc Res , vol.56 , pp. 126-134
    • Zeuke, S.1    Ulmer, A.J.2    Kusumoto, S.3    Katus, H.A.4    Heine, H.5
  • 9
    • 0028901615 scopus 로고
    • Transcriptional regulation of endothelial cell adhesion molecules: A dominant role for NF-kappa B
    • Chen CC, Manning AM. Transcriptional regulation of endothelial cell adhesion molecules: A dominant role for NF-kappa B. Agents Actions Suppl 1995;47:135-141.
    • (1995) Agents Actions Suppl , vol.47 , pp. 135-141
    • Chen, C.C.1    Manning, A.M.2
  • 10
    • 0029101772 scopus 로고
    • Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers
    • Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. FASEB J 1995;9:899-909.
    • (1995) FASEB J , vol.9 , pp. 899-909
    • Collins, T.1    Read, M.A.2    Neish, A.S.3    Whitley, M.Z.4    Thanos, D.5    Maniatis, T.6
  • 12
    • 1542373649 scopus 로고    scopus 로고
    • Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP
    • Andreakos E, Sacre SM, Smith C, Lundberg A, Kiriakidis S, Stonehouse T, Monaco C, Feldmann M, Foxwell BM. Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP. Blood 2004;103:2229-2237.
    • (2004) Blood , vol.103 , pp. 2229-2237
    • Andreakos, E.1    Sacre, S.M.2    Smith, C.3    Lundberg, A.4    Kiriakidis, S.5    Stonehouse, T.6    Monaco, C.7    Feldmann, M.8    Foxwell, B.M.9
  • 13
    • 33846932789 scopus 로고    scopus 로고
    • Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic acid (LTA) induced NF-kappaB activation and cytokine production in primary human cells: TRAM is an adaptor for LPS and LTA signaling
    • Sacre SM, Lundberg AM, Andreakos E, Taylor C, Feldmann M, Foxwell BM. Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic acid (LTA) induced NF-kappaB activation and cytokine production in primary human cells: TRAM is an adaptor for LPS and LTA signaling. J Immunol 2007;178:2148-2154.
    • (2007) J Immunol , vol.178 , pp. 2148-2154
    • Sacre, S.M.1    Lundberg, A.M.2    Andreakos, E.3    Taylor, C.4    Feldmann, M.5    Foxwell, B.M.6
  • 14
    • 4143101842 scopus 로고    scopus 로고
    • Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: Roles of LBP and sCD14 in mediating LPS responses
    • Dunzendorfer S, Lee HK, Soldau K, Tobias PS. Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: roles of LBP and sCD14 in mediating LPS responses. FASEB J 2004;18:1117-1119.
    • (2004) FASEB J , vol.18 , pp. 1117-1119
    • Dunzendorfer, S.1    Lee, H.K.2    Soldau, K.3    Tobias, P.S.4
  • 15
    • 0033583034 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
    • Zhang FX, Kirschning CJ, Mancinelli R, Xu XP, Jin Y, Faure E, Mantovani A, Rothe M, Muzio M, Arditi M. Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J Biol Chem 1999;274:7611-7614.
    • (1999) J Biol Chem , vol.274 , pp. 7611-7614
    • Zhang, F.X.1    Kirschning, C.J.2    Mancinelli, R.3    Xu, X.P.4    Jin, Y.5    Faure, E.6    Mantovani, A.7    Rothe, M.8    Muzio, M.9    Arditi, M.10
  • 16
    • 45149123112 scopus 로고    scopus 로고
    • TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia
    • Gong P, Angelini DJ, Yang S, Xia G, Cross AS, Mann D, Bannerman DD, Vogel SN, Goldblum SE. TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia. J Biol Chem 2008;283:13437-13449.
    • (2008) J Biol Chem , vol.283 , pp. 13437-13449
    • Gong, P.1    Angelini, D.J.2    Yang, S.3    Xia, G.4    Cross, A.S.5    Mann, D.6    Bannerman, D.D.7    Vogel, S.N.8    Goldblum, S.E.9
  • 17
    • 34147099560 scopus 로고    scopus 로고
    • TNFR1-induced NF-kappaB but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells
    • Zhou Z, Connell MC, MacEwan DJ. TNFR1-induced NF-kappaB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells. Cell Signal 2007;19:1238-1248.
    • (2007) Cell Signal , vol.19 , pp. 1238-1248
    • Zhou, Z.1    Connell, M.C.2    MacEwan, D.J.3
  • 18
    • 26844462934 scopus 로고    scopus 로고
    • Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro
    • Kuldo JM, Westra J, Asgeirsdottir SA, Kok RJ, Oosterhuis K, Rots MG, Schouten JP, Limburg PC, Molema G. Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro. Am J Physiol Cell Physiol 2005;289:C1229-C1239.
    • (2005) Am J Physiol Cell Physiol , vol.289
    • Kuldo, J.M.1    Westra, J.2    Asgeirsdottir, S.A.3    Kok, R.J.4    Oosterhuis, K.5    Rots, M.G.6    Schouten, J.P.7    Limburg, P.C.8    Molema, G.9
  • 19
    • 0142026209 scopus 로고    scopus 로고
    • Lee JC. p38 MAP kinases: Key signaling molecules as therapeutic targets for inflammatory diseases
    • Kumar S, Boehm J, Lee JC. p38 MAP kinases: Key signaling molecules as therapeutic targets for inflammatory diseases. Nat Rev Drug Discov 2003;2:717-726.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 717-726
    • Kumar, S.1    Boehm, J.2
  • 20
    • 0142116222 scopus 로고    scopus 로고
    • Methemoglobin is a potent activator of endothelial cells by stimulating IL-6 and IL-8 production and E-selectin membrane expression
    • Liu X, Spolarics Z. Methemoglobin is a potent activator of endothelial cells by stimulating IL-6 and IL-8 production and E-selectin membrane expression. Am J Physiol Cell Physiol 2003;285:C1036-C1046.
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Liu, X.1    Spolarics, Z.2
  • 21
    • 0036345749 scopus 로고    scopus 로고
    • TNF-alpha, inefficient by itself, potentiates IL-1beta-induced PGHS-2 expression in human pulmonary microvascular endothelial cells: Requirement of NF-kappaB and p38 MAPK pathways
    • Said FA, Werts C, Elalamy I, Couetil JP, Jacquemin C, Hatmi M. TNF-alpha, inefficient by itself, potentiates IL-1beta-induced PGHS-2 expression in human pulmonary microvascular endothelial cells: requirement of NF-kappaB and p38 MAPK pathways. Br J Pharmacol 2002;136:1005-1014.
    • (2002) Br J Pharmacol , vol.136 , pp. 1005-1014
    • Said, F.A.1    Werts, C.2    Elalamy, I.3    Couetil, J.P.4    Jacquemin, C.5    Hatmi, M.6
  • 23
    • 4644354101 scopus 로고    scopus 로고
    • The volatile anesthetics halothane and isoflurane differentially modulate proinflammatory cytokine-induced p38 mitogen-activated protein kinase activation
    • Itoh T, Hirota K, Hisano T, Namba T, Fukuda K. The volatile anesthetics halothane and isoflurane differentially modulate proinflammatory cytokine-induced p38 mitogen-activated protein kinase activation. J Anesth 2004;18:203-209.
    • (2004) J Anesth , vol.18 , pp. 203-209
    • Itoh, T.1    Hirota, K.2    Hisano, T.3    Namba, T.4    Fukuda, K.5
  • 24
    • 0345826140 scopus 로고    scopus 로고
    • Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation
    • Gustin JA, Ozes ON, Akca H, Pincheira R, Mayo LD, Li Q, Guzman JR, Korgaonkar CK, Donner DB. Cell type-specific expression of the IkappaB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-kappa B activation. J Biol Chem 2004;279:1615-1620.
    • (2004) J Biol Chem , vol.279 , pp. 1615-1620
    • Gustin, J.A.1    Ozes, O.N.2    Akca, H.3    Pincheira, R.4    Mayo, L.D.5    Li, Q.6    Guzman, J.R.7    Korgaonkar, C.K.8    Donner, D.B.9
  • 25
    • 68149162037 scopus 로고    scopus 로고
    • Leukocyte-endothelial interactions in inflammation
    • Langer HF, Chavakis T. Leukocyte-endothelial interactions in inflammation. J Cell Mol Med 2009;13:1211-1220.
    • (2009) J Cell Mol Med , vol.13 , pp. 1211-1220
    • Langer, H.F.1    Chavakis, T.2
  • 26
    • 34249096660 scopus 로고    scopus 로고
    • The specific role of chemokines in atherosclerosis
    • Braunersreuther V, Mach F, Steffens S. The specific role of chemokines in atherosclerosis. Thromb Haemost 2007;97:714-721.
    • (2007) Thromb Haemost , vol.97 , pp. 714-721
    • Braunersreuther, V.1    Mach, F.2    Steffens, S.3
  • 27
    • 33748753161 scopus 로고    scopus 로고
    • Lipopolysaccharide and TNF-alpha produce very similar changes in gene expression in human endothelial cells
    • Magder S, Neculcea J, Neculcea V, Sladek R. Lipopolysaccharide and TNF-alpha produce very similar changes in gene expression in human endothelial cells. J Vasc Res 2006;43:447-461.
    • (2006) J Vasc Res , vol.43 , pp. 447-461
    • Magder, S.1    Neculcea, J.2    Neculcea, V.3    Sladek, R.4
  • 28
    • 0035195520 scopus 로고    scopus 로고
    • Human endothelial cell response to gram-negative lipopolysaccharide assessed with cDNA microarrays
    • Zhao B, Bowden RA, Stavchansky SA, Bowman PD. Human endothelial cell response to gram-negative lipopolysaccharide assessed with cDNA microarrays. Am J Physiol Cell Physiol 2001;281:C1587-C1595.
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Zhao, B.1    Bowden, R.A.2    Stavchansky, S.A.3    Bowman, P.D.4
  • 29
    • 0037911635 scopus 로고    scopus 로고
    • Effect of interleukin-1beta and tumor necrosis factor-alpha on gene expression in human endothelial cells
    • Zhao B, Stavchansky SA, Bowden RA, Bowman PD. Effect of interleukin-1beta and tumor necrosis factor-alpha on gene expression in human endothelial cells. Am J Physiol Cell Physiol 2003;284:C1577-C1583.
    • (2003) Am J Physiol Cell Physiol , vol.284
    • Zhao, B.1    Stavchansky, S.A.2    Bowden, R.A.3    Bowman, P.D.4
  • 30
    • 0030001831 scopus 로고    scopus 로고
    • Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells
    • Haraldsen G, Kvale D, Lien B, Farstad IN, Brandtzaeg P. Cytokine-regulated expression of E-selectin, intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in human microvascular endothelial cells. J Immunol 1996;156:2558-2565.
    • (1996) J Immunol , vol.156 , pp. 2558-2565
    • Haraldsen, G.1    Kvale, D.2    Lien, B.3    Farstad, I.N.4    Brandtzaeg, P.5
  • 31
    • 33244483600 scopus 로고    scopus 로고
    • The dynamics of gene expression in human lung microvascular endothelial cells after stimulation with inflammatory cytokines
    • Zachlederova M, Jarolim P. The dynamics of gene expression in human lung microvascular endothelial cells after stimulation with inflammatory cytokines. Physiol Res 2006;55:39-47.
    • (2006) Physiol Res , vol.55 , pp. 39-47
    • Zachlederova, M.1    Jarolim, P.2
  • 33
    • 0036590653 scopus 로고    scopus 로고
    • The role of MAP kinases in endothelial activation
    • Hoefen RJ, Berk BC. The role of MAP kinases in endothelial activation. Vascul Pharmacol 2002;38:271-273.
    • (2002) Vascul Pharmacol , vol.38 , pp. 271-273
    • Hoefen, R.J.1    Berk, B.C.2
  • 35
    • 3142690482 scopus 로고    scopus 로고
    • TLR4 is the signaling but not the lipopolysaccharide uptake receptor
    • Dunzendorfer S, Lee HK, Soldau K, Tobias PS. TLR4 is the signaling but not the lipopolysaccharide uptake receptor. J Immunol 2004;173:1166-1170.
    • (2004) J Immunol , vol.173 , pp. 1166-1170
    • Dunzendorfer, S.1    Lee, H.K.2    Soldau, K.3    Tobias, P.S.4
  • 36
    • 0037018107 scopus 로고    scopus 로고
    • Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells
    • Hornef MW, Frisan T, Vandewalle A, Normark S, Richter-Dahlfors A. Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J Exp Med 2002;195:559-570.
    • (2002) J Exp Med , vol.195 , pp. 559-570
    • Hornef, M.W.1    Frisan, T.2    Vandewalle, A.3    Normark, S.4    Richter-Dahlfors, A.5
  • 37
    • 24944489952 scopus 로고    scopus 로고
    • Stimulus specificity of gene expression programs determined by temporal control of IKK activity
    • Werner SL, Barken D, Hoffmann A. Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 2005;309:1857-1861.
    • (2005) Science , vol.309 , pp. 1857-1861
    • Werner, S.L.1    Barken, D.2    Hoffmann, A.3
  • 40
    • 33745053205 scopus 로고    scopus 로고
    • Absence of TRAM restricts toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway
    • Harari OA, Alcaide P, Ahl D, Luscinskas FW, Liao JK. Absence of TRAM restricts toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway. Circ Res 2006;98:1134-1140.
    • (2006) Circ Res , vol.98 , pp. 1134-1140
    • Harari, O.A.1    Alcaide, P.2    Ahl, D.3    Luscinskas, F.W.4    Liao, J.K.5
  • 41
    • 66449092314 scopus 로고    scopus 로고
    • Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity
    • Shih VF, Kearns JD, Basak S, Savinova OV, Ghosh G, Hoffmann A. Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity. Proc Natl Acad Sci USA 2009;106:9619-9624.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9619-9624
    • Shih, V.F.1    Kearns, J.D.2    Basak, S.3    Savinova, O.V.4    Ghosh, G.5    Hoffmann, A.6
  • 42
    • 0035920176 scopus 로고    scopus 로고
    • A novel IkappaB protein. IkappaB-zeta, induced by proinflammatory stimuli, negatively regulates nuclear factor-kappaB in the nuclei
    • Yamazaki S, Muta T, Takeshige K. A novel IkappaB protein. IkappaB-zeta, induced by proinflammatory stimuli, negatively regulates nuclear factor-kappaB in the nuclei. J Biol Chem 2001;276:27657-27662.
    • (2001) J Biol Chem , vol.276 , pp. 27657-27662
    • Yamazaki, S.1    Muta, T.2    Takeshige, K.3
  • 43
    • 4043096879 scopus 로고    scopus 로고
    • Lipopolysaccharide-mediated cell activation without rapid mobilization of cytosolic free calcium
    • Bosshart H, Heinzelmann M. Lipopolysaccharide-mediated cell activation without rapid mobilization of cytosolic free calcium. Mol Immunol 2004;41:1023-1028.
    • (2004) Mol Immunol , vol.41 , pp. 1023-1028
    • Bosshart, H.1    Heinzelmann, M.2
  • 44
    • 0031658716 scopus 로고    scopus 로고
    • Selectivity of endotoxin-induced defect in endothelial calcium mobilization
    • Umans JG, Salvi D, Murray PT, Wylam ME. Selectivity of endotoxin-induced defect in endothelial calcium mobilization. Kidney Int 1998;54:1063-1069.
    • (1998) Kidney Int , vol.54 , pp. 1063-1069
    • Umans, J.G.1    Salvi, D.2    Murray, P.T.3    Wylam, M.E.4
  • 45
    • 0034685915 scopus 로고    scopus 로고
    • A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells
    • Madge LA, Pober JS. A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells. J Biol Chem 2000;275:15458-15465.
    • (2000) J Biol Chem , vol.275 , pp. 15458-15465
    • Madge, L.A.1    Pober, J.S.2
  • 46
    • 1542267431 scopus 로고    scopus 로고
    • Escherichia coli Shiga toxin 1 and TNF-alpha induce cytokine release by human cerebral microvascular endothelial cells
    • Eisenhauer PB, Jacewicz MS, Conn KJ, Koul O, Wells JM, Fine RE, Newburg DS. Escherichia coli Shiga toxin 1 and TNF-alpha induce cytokine release by human cerebral microvascular endothelial cells. Microb Pathog 2004;36:189-196.
    • (2004) Microb Pathog , vol.36 , pp. 189-196
    • Eisenhauer, P.B.1    Jacewicz, M.S.2    Conn, K.J.3    Koul, O.4    Wells, J.M.5    Fine, R.E.6    Newburg, D.S.7
  • 47
    • 3242697885 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor inhibits TNF-alpha-induced interleukin-6 expression in endothelial cells by suppressing NADPH oxidase-mediated reactive oxygen species generation
    • Yamagishi S, Inagaki Y, Nakamura K, Abe R, Shimizu T, Yoshimura A, Imaizumi T. Pigment epithelium-derived factor inhibits TNF-alpha-induced interleukin-6 expression in endothelial cells by suppressing NADPH oxidase-mediated reactive oxygen species generation. J Mol Cell Cardiol 2004;37:497-506.
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 497-506
    • Yamagishi, S.1    Inagaki, Y.2    Nakamura, K.3    Abe, R.4    Shimizu, T.5    Yoshimura, A.6    Imaizumi, T.7
  • 48
    • 0035119112 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide and tumor necrosis factor alpha synergistically increase expression of human endothelial adhesion molecules through activation of NF-kappaB and p38 mitogen-activated protein kinase signaling pathways
    • Jersmann HP, Hii CS, Ferrante JV, Ferrante A. Bacterial lipopolysaccharide and tumor necrosis factor alpha synergistically increase expression of human endothelial adhesion molecules through activation of NF-kappaB and p38 mitogen-activated protein kinase signaling pathways. Infect Immun 2001;69:1273-1279.
    • (2001) Infect Immun , vol.69 , pp. 1273-1279
    • Jersmann, H.P.1    Hii, C.S.2    Ferrante, J.V.3    Ferrante, A.4
  • 49
    • 13444305306 scopus 로고    scopus 로고
    • TRED: A transcriptional regulatory element database and a platform for in silico gene regulation studies
    • Zhao F, Xuan Z, Liu L, Zhang MQ TRED: A transcriptional regulatory element database and a platform for in silico gene regulation studies. Nucleic Acids Res 2005;33:D103-D107.
    • (2005) Nucleic Acids Res , vol.33
    • Zhao, F.1    Xuan, Z.2    Liu, L.3    Zhang, M.Q.4


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