-
1
-
-
33748601470
-
Structural biology and chemistry of the terpenoid cyclases
-
Christianson, D. W. Structural biology and chemistry of the terpenoid cyclases. Chem. Rev. 106, 3412-3442 (2006).
-
(2006)
Chem. Rev.
, vol.106
, pp. 3412-3442
-
-
Christianson, D.W.1
-
2
-
-
33748631825
-
Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: Logic, machinery, and mechanisms
-
Fischbach, M. A. & Walsh, C. T. Assembly-line enzymology for polyketide and nonribosomal peptide antibiotics: logic, machinery, and mechanisms. Chem. Rev. 106, 3468-3496 (2006).
-
(2006)
Chem. Rev.
, vol.106
, pp. 3468-3496
-
-
Fischbach, M.A.1
Walsh, C.T.2
-
3
-
-
68249113421
-
Meroterpenoids produced by fungi
-
Geris, R. & Simpson, T. J. Meroterpenoids produced by fungi. Nat. Prod. Rep. 26, 1063-1097 (2009).
-
(2009)
Nat. Prod. Rep.
, vol.26
, pp. 1063-1097
-
-
Geris, R.1
Simpson, T.J.2
-
4
-
-
0027279354
-
Pyripyropenes, highly potent inhibitiors of Acyl-CoA: Cholesterol acyltransferase produced by Aspergillus fumigatus [1]
-
Ōmura, S., Tomoda, H., Kim, Y. K. & Nishida, H. Pyripyropenes, highly potent inhibitors of acyl-CoA: cholesterol acyltransferase produced by Aspergillus fumigatus. J. Antibiot. 46, 1168-1169 (1993). (Pubitemid 23254161)
-
(1993)
Journal of Antibiotics
, vol.46
, Issue.7
, pp. 1168-1169
-
-
Omura, S.1
Tomoda, H.2
Kim, Y.K.3
Nishida, H.4
-
5
-
-
0028350015
-
Pyripyropenes, novel inhibitors of acyl-coa: Cholesterol acyltransferase produced by Aspergillus fumigatus
-
Tomoda, H., Kim, Y. K., Nishida, H., Masuma, R. & Ōmura, S. Pyripyropenes, novel inhibitors of acyl-CoA: cholesterol acyltransferase produced by Aspergillus fumigatus. J. Antibiot. 47, 148-153 (1994).
-
(1994)
J. Antibiot.
, vol.47
, pp. 148-153
-
-
Tomoda, H.1
Kim, Y.K.2
Nishida, H.3
Masuma, R.4
Omura, S.5
-
6
-
-
44849092966
-
Identification of the interaction site within acyl-coa:cholesterol acyltransferase 2 for the isoform-specific inhibitor pyripyropene A
-
Das, A., Davis, M. A., Tomoda, H., Ōmura, S. & Rudel, L. L. Identification of the interaction site within acyl-CoA:cholesterol acyltransferase 2 for the isoform-specific inhibitor pyripyropene A. J. Biol. Chem. 283, 10453-10460 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10453-10460
-
-
Das, A.1
Davis, M.A.2
Tomoda, H.3
Omura, S.4
Rudel, L.L.5
-
8
-
-
0029793496
-
Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259
-
Kuno, F., Otoguro, K., Shiomi, K., Iwai, Y. & Ōmura, S. Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. J. Antibiot. 49, 742-747 (1996).
-
(1996)
J. Antibiot.
, vol.49
, pp. 742-747
-
-
Kuno, F.1
Otoguro, K.2
Shiomi, K.3
Iwai, Y.4
Omura, S.5
-
9
-
-
0033521107
-
Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism
-
Chen, J. W., Luo, Y. L., Hwang, M. J., Peng, F. C. & Ling, K. H. Territrem B, a tremorgenic mycotoxin that inhibits acetylcholinesterase with a noncovalent yet irreversible binding mechanism. J. Biol. Chem. 274, 34916-34923 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34916-34923
-
-
Chen, J.W.1
Luo, Y.L.2
Hwang, M.J.3
Peng, F.C.4
Ling, K.H.5
-
10
-
-
33847698929
-
Synthesis and biological activity of novel pyranopyrones derived from engineered aromatic polyketides
-
Ridley, C. P. & Khosla, C. Synthesis and biological activity of novel pyranopyrones derived from engineered aromatic polyketides. ACS Chem. Biol. 2, 104-108 (2007).
-
(2007)
ACS Chem. Biol.
, vol.2
, pp. 104-108
-
-
Ridley, C.P.1
Khosla, C.2
-
11
-
-
20544457539
-
Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products
-
DOI 10.1038/nature03668
-
Kuzuyama, T., Noel, J. P. & Richard, S. B. Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products. Nature 435, 983-987 (2005). (Pubitemid 40896327)
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 983-987
-
-
Kuzuyama, T.1
Noel, J.P.2
Richard, S.B.3
-
12
-
-
32444437181
-
Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: Identification and heterologous expression of the gene cluster
-
DOI 10.1128/JB.188.4.1236-1244.2006
-
Kawasaki, T. et al. Biosynthesis of a natural polyketide-isoprenoid hybrid compound, furaquinocin A: identification and heterologous expression of the gene cluster. J. Bacteriol. 188, 1236-1244 (2006). (Pubitemid 43228655)
-
(2006)
Journal of Bacteriology
, vol.188
, Issue.4
, pp. 1236-1244
-
-
Kawasaki, T.1
Hayashi, Y.2
Kuzuyama, T.3
Furihata, K.4
Itoh, N.5
Seto, H.6
Dairi, T.7
-
13
-
-
33845468380
-
A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042
-
Haagen, Y. et al. A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042. ChemBioChem 7, 2016-2027 (2006).
-
(2006)
ChemBioChem
, vol.7
, pp. 2016-2027
-
-
Haagen, Y.1
-
14
-
-
34447558011
-
Molecular basis for chloronium-mediated meroterpene cyclization
-
Winter, J. M. et al. Molecular basis for chloronium-mediated meroterpene cyclization. J. Biol. Chem. 282, 16362-16368 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 16362-16368
-
-
Winter, J.M.1
-
15
-
-
0030060848
-
Biosynthesis of pyripyropene A
-
DOI 10.1021/jo951424s
-
Tomoda, H. et al. Biosynthesis of pyripyropene A. J. Org. Chem. 61, 882-886 (1996). (Pubitemid 26069745)
-
(1996)
Journal of Organic Chemistry
, vol.61
, Issue.3
, pp. 882-886
-
-
Tomoda, H.1
Tabata, N.2
Nakata, Y.3
Nishida, H.4
Kaneko, T.5
Obata, R.6
Sunazuka, T.7
Omura, S.8
-
16
-
-
28644434509
-
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
-
DOI 10.1038/nature04332
-
Nierman, W. C. et al. Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature 438, 1151-1156 (2005). (Pubitemid 41831684)
-
(2005)
Nature
, vol.438
, Issue.7071
, pp. 1151-1156
-
-
Nierman, W.C.1
Pain, A.2
Anderson, M.J.3
Wortman, J.R.4
Kim, H.S.5
Arroyo, J.6
Berriman, M.7
Abe, K.8
Archer, D.B.9
Bermejo, C.10
Bennett, J.11
Bowyer, P.12
Chen, D.13
Collins, M.14
Coulsen, R.15
Davies, R.16
Dyer, P.S.17
Farman, M.18
Fedorova, N.19
Fedorova, N.20
Feldblyum, T.V.21
Fischer, R.22
Fosker, N.23
Fraser, A.24
Garcia, J.L.25
Garcia, M.J.26
Goble, A.27
Goldman, G.H.28
Gomi, K.29
Griffith-Jones, S.30
Gwilliam, R.31
Haas, B.32
Haas, H.33
Harris, D.34
Horiuchi, H.35
Huang, J.36
Humphray, S.37
Jimenez, J.38
Keller, N.39
Khouri, H.40
Kitamoto, K.41
Kobayashi, T.42
Konzack, S.43
Kulkarni, R.44
Kumagai, T.45
Lafton, A.46
Latge, J.-P.47
Li, W.48
Lord, A.49
Lu, C.50
Majoros, W.H.51
May, G.S.52
Miller, B.L.53
Mohamoud, Y.54
Molina, M.55
Monod, M.56
Mouyna, I.57
Mulligan, S.58
Murphy, L.59
O'Neil, S.60
Paulsen, I.61
Penalva, M.A.62
Pertea, M.63
Price, C.64
Pritchard, B.L.65
Quail, M.A.66
Rabbinowitsch, E.67
Rawlins, N.68
Rajandream, M.-A.69
Reichard, U.70
Renauld, H.71
Robson, G.D.72
Rodriguez De Cordoba, S.73
Rodriguez-Pena, J.M.74
Ronning, C.M.75
Rutter, S.76
Salzberg, S.L.77
Sanchez, M.78
Sanchez-Ferrero, J.C.79
Saunders, D.80
Seeger, K.81
Squares, R.82
Squares, S.83
Takeuchi, M.84
Tekaia, F.85
Turner, G.86
Vazquez De Aldana, C.R.87
Weidman, J.88
White, O.89
Woodward, J.90
Yu, J.-H.91
Fraser, C.92
Galagan, J.E.93
Asai, K.94
Machida, M.95
Hall, N.96
Barrell, B.97
Denning, D.W.98
more..
-
17
-
-
0029857563
-
Cloning of the polyketide synthase gene atX from Aspergillus terreus and its identification as the 6-methylsalicylic acid synthase gene by heterologous expression
-
DOI 10.1007/s004380050289
-
Fujii, I. et al. Cloning of the polyketide synthase gene atX from Aspergillus terreus and its identification as the 6-methylsalicylic acid synthase gene by heterologous expression. Mol. Gen. Genet. 253, 1-10 (1996). (Pubitemid 26419981)
-
(1996)
Molecular and General Genetics
, vol.253
, Issue.1-2
, pp. 1-10
-
-
Fujii, I.1
Ono, Y.2
Tada, H.3
Gomi, K.4
Ebizuka, Y.5
Sankawa, U.6
-
18
-
-
0032532795
-
Product identification of polyketide synthase coded by Aspergillus nidulans wA gene
-
PII S0040403998016852
-
Watanabe, A. et al. Product identification of polyketide synthase coded by Aspergillus nidulans wA gene. Tetrahedron Lett. 39, 7733-7736 (1998). (Pubitemid 28540902)
-
(1998)
Tetrahedron Letters
, vol.39
, Issue.42
, pp. 7733-7736
-
-
Watanabe, A.1
Ono, Y.2
Fujii, I.3
Sankawa, U.4
Mayorga, M.E.5
Timberlake, W.E.6
Ebizuka, Y.7
-
19
-
-
0032890191
-
Re-identification of Aspergillus nidulans wA gene to code for a polyketide synthase of naphthopyrone
-
DOI 10.1016/S0040-4039(98)80027-0, PII S0040403998022850
-
Watanabe, A. et al. Re-identification of Aspergillus nidulans wA gene to code for a polyketide synthase of naphthopyrone. Tetrahedron Lett. 40, 91-94 (1999). (Pubitemid 28561826)
-
(1999)
Tetrahedron Letters
, vol.40
, Issue.1
, pp. 91-94
-
-
Watanabe, A.1
Fujii, I.2
Sankawa, U.3
Mayorga, M.E.4
Timberlake, W.E.5
Ebizuka, Y.6
-
20
-
-
0033173472
-
Heterologous expression and product identification of Colletotrichum lagenarium polyketide synthase encoded by the PKS1 gene involved in melanin biosynthesis
-
Fujii, I. et al. Heterologous expression and product identification of Colletotrichum lagenarium polyketide synthase encoded by the PKS1 gene involved in melanin biosynthesis. Biosci. Biotechnol. Biochem. 63, 1445-1452 (1999). (Pubitemid 129549158)
-
(1999)
Bioscience, Biotechnology and Biochemistry
, vol.63
, Issue.8
, pp. 1445-1452
-
-
Fujii, I.1
Mori, Y.2
Watanabe, A.3
Kubo, Y.4
Tsuji, G.5
Ebizuka, Y.6
-
21
-
-
0034254579
-
Enzymatic synthesis of 1,3,6,8-tetrahydroxynaphthalene solely from malonyl coenzyme a by a fungal iterative type I polyketide synthase PKS1
-
DOI 10.1021/bi000644j
-
Fujii, I. et al. Enzymatic synthesis of 1,3,6,8-tetrahydroxynaphthalene solely from malonyl coenzyme A by a fungal iterative type I polyketide synthase PKS1. Biochemistry 39, 8853-8858 (2000). (Pubitemid 30602795)
-
(2000)
Biochemistry
, vol.39
, Issue.30
, pp. 8853-8858
-
-
Fujii, I.1
Mori, Y.2
Watanabe, A.3
Kubo, Y.4
Tsuji, G.5
Ebizuka, Y.6
-
22
-
-
0034333341
-
Aspergillus fumigatus alb1 encodes naphthopyrone synthase when expressed in Aspergillus oryzae
-
Watanabe, A. et al. Aspergillus fumigatus alb1 encodes naphthopyrone synthase when expressed in Aspergillus oryzae. FEMS Microbiol. Lett. 192, 39-44 (2000).
-
(2000)
FEMS Microbiol. Lett.
, vol.192
, pp. 39-44
-
-
Watanabe, A.1
-
23
-
-
0035068075
-
Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans
-
DOI 10.1016/S1074-5521(00)90068-1, PII S1074552100900681
-
Fujii, I., Watanabe, A., Sankawa, U. & Ebizuka, Y. Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans. Chem. Biol. 8, 189-197 (2001). (Pubitemid 32296109)
-
(2001)
Chemistry and Biology
, vol.8
, Issue.2
, pp. 189-197
-
-
Fujii, I.1
Watanabe, A.2
Sankawa, U.3
Ebizuka, Y.4
-
24
-
-
28844465191
-
An iterative type I polyketide synthase PKSN catalyzes synthesis of the decaketide alternapyrone with regio-specific octa-methylation
-
DOI 10.1016/j.chembiol.2005.09.015, PII S1074552105003108
-
Fujii, I., Yoshida, N., Shimomaki, S., Oikawa, H. & Ebizuka, Y. An iterative type I polyketide synthase PKSN catalyzes synthesis of the decaketide alternapyrone with regio-specific octa-methylation. Chem. Biol. 12, 1301-1309 (2005). (Pubitemid 41779470)
-
(2005)
Chemistry and Biology
, vol.12
, Issue.12
, pp. 1301-1309
-
-
Fujii, I.1
Yoshida, N.2
Shimomaki, S.3
Oikawa, H.4
Ebizuka, Y.5
-
25
-
-
33745325159
-
Expression of Alternaria solani PKSF generates a set of complex reduced-type polyketides with different carbon-lengths and cyclization
-
DOI 10.1002/cbic.200600034
-
Kasahara, K., Fujii, I., Oikawa, H. & Ebizuka, Y. Expression of Alternaria solani PKSF generates a set of complex reduced-type polyketides with different carbon-lengths and cyclization. ChemBioChem 7, 920-924 (2006). (Pubitemid 43938613)
-
(2006)
ChemBioChem
, vol.7
, Issue.6
, pp. 920-924
-
-
Kasahara, K.1
Fujii, I.2
Oikawa, H.3
Ebizuka, Y.4
-
26
-
-
0029090539
-
GERI-BP001 compounds, new inhibitors of acyl-coa: Cholesterol acyltransferase from aspergillus fumigatus F37
-
Jeong, T. S. et al. GERI-BP001 compounds, new inhibitors of acyl-CoA: cholesterol acyltransferase from Aspergillus fumigatus F37. J. Antibiot. 48, 751-756 (1995).
-
(1995)
J. Antibiot.
, vol.48
, pp. 751-756
-
-
Jeong, T.S.1
-
27
-
-
65349101892
-
Prenyl transfer to aromatic substrates: Genetics and enzymology
-
Heide, L. Prenyl transfer to aromatic substrates: genetics and enzymology. Curr. Opin. Chem. Biol. 13, 171-179 (2009).
-
(2009)
Curr. Opin. Chem. Biol.
, vol.13
, pp. 171-179
-
-
Heide, L.1
-
28
-
-
33846438613
-
Lewis acid-promoted intermolecular acetal-initiated cationic polyene cyclizations
-
Zhao, Y. J., Chng, S. S. & Loh, T. P. Lewis acid-promoted intermolecular acetal-initiated cationic polyene cyclizations. J. Am. Chem. Soc. 129, 492-493 (2007).
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 492-493
-
-
Zhao, Y.J.1
Chng, S.S.2
Loh, T.P.3
-
29
-
-
33344460613
-
Four gene products are required for the fungal synthesis of the indole-diterpene, paspaline
-
DOI 10.1016/j.febslet.2006.02.008, PII S0014579306001955
-
Saikia, S., Parker, E. J., Koulman, A. & Scott, B. Four gene products are required for the fungal synthesis of the indole-diterpene, paspaline. FEBS Lett. 580, 1625-1630 (2006). (Pubitemid 43290362)
-
(2006)
FEBS Letters
, vol.580
, Issue.6
, pp. 1625-1630
-
-
Saikia, S.1
Parker, E.J.2
Koulman, A.3
Scott, B.4
-
30
-
-
0035137305
-
Molecular cloning and genetic analysis of an indolediterpene gene cluster from Penicillium paxilli
-
DOI 10.1046/j.1365-2958.2001.02265.x
-
Young, C., McMillan, L., Telfer, E. & Scott, B. Molecular cloning and genetic analysis of an indole-diterpene gene cluster from Penicillium paxilli. Mol. Microbiol. 39, 754-764 (2001). (Pubitemid 32158153)
-
(2001)
Molecular Microbiology
, vol.39
, Issue.3
, pp. 754-764
-
-
Scott, B.1
Young, C.2
McMillan, L.3
Telfer, E.4
-
31
-
-
8744243225
-
Indole-diterpene gene cluster from Aspergillus flavus
-
DOI 10.1128/AEM.70.11.6875-6883.2004
-
Zhang, S., Monahan, B. J., Tkacz, J. S. & Scott, B. Indole-diterpene gene cluster from Aspergillus flavus. Appl. Environ. Microbiol. 70, 6875-6883 (2004). (Pubitemid 39518601)
-
(2004)
Applied and Environmental Microbiology
, vol.70
, Issue.11
, pp. 6875-6883
-
-
Zhang, S.1
Monahan, B.J.2
Tkacz, J.S.3
Scott, B.4
-
32
-
-
15544389776
-
Studies on biosynthetic genes and enzymes of isoprenoids produced by actinomycetes
-
Dairi, T. Studies on biosynthetic genes and enzymes of isoprenoids produced by actinomycetes. J. Antibiot. 58, 227-243 (2005). (Pubitemid 40740598)
-
(2005)
Journal of Antibiotics
, vol.58
, Issue.4
, pp. 227-243
-
-
Dairi, T.1
-
33
-
-
0030565604
-
Biomimetic total synthesis of the ACAT inhibitor (+)-pyripyropene E
-
DOI 10.1016/0040-4039(96)01439-6
-
Smith, A. B. III, Kinsho, T., Sunazuka, T. & Ō mura, S. Biomimetic total synthesis of the ACAT inhibitor (+)-pyripyropene E. Tetrahedron Lett. 37, 6461-6464 (1996). (Pubitemid 26278262)
-
(1996)
Tetrahedron Letters
, vol.37
, Issue.36
, pp. 6461-6464
-
-
Smith III, A.B.1
Kinsho, T.2
Sunazuka, T.3
Omura, S.4
-
34
-
-
8544273685
-
Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase
-
DOI 10.1038/nature02993
-
Thoma, R. et al. Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase. Nature 432, 118-122 (2004). (Pubitemid 39490838)
-
(2004)
Nature
, vol.432
, Issue.7013
, pp. 118-122
-
-
Thoma, R.1
Schulz-Gasen, T.2
D'Arcy, B.3
Benz, J.4
Aebi, J.5
Dehmlow, H.6
Hennig, M.7
Stihle, M.8
Ruf, A.9
-
35
-
-
0037959568
-
S14-95, a novel inhibitor of the JAK/STAT pathway from a Penicillium species
-
Erkel, G., Rether, J., Anke, T. & Sterner, O. S14-95, a novel inhibitor of the JAK/STAT pathway from a Penicillium species. J. Antibiot. 56, 337-343 (2003). (Pubitemid 36575938)
-
(2003)
Journal of Antibiotics
, vol.56
, Issue.4
, pp. 337-343
-
-
Erkel, G.1
Rether, J.2
Anke, T.3
Sterner, O.4
|