-
1
-
-
4344578939
-
An antibiotic factory caught in action
-
Keatinge-Clay, A. T., Maltby, D. A., Medzihradszky, K. F., Khosla, C., and Stroud, R. M. (2004) An antibiotic factory caught in action, Nat. Struct. Mol. Biol. 11, 888-893.
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 888-893
-
-
Keatinge-Clay, A.T.1
Maltby, D.A.2
Medzihradszky, K.F.3
Khosla, C.4
Stroud, R.M.5
-
2
-
-
0027908014
-
Engineered biosynthesis of novel polyketides
-
McDaniel, R., Ebert-Khosla, S., Hopwood, D. A., and Khosla, C. (1993) Engineered biosynthesis of novel polyketides, Science 262, 1546-1550.
-
(1993)
Science
, vol.262
, pp. 1546-1550
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
3
-
-
0027964653
-
Engineered biosynthesis of novel polyketides: Stereochemical course of two reactions catalyzed by a polyketide synthase
-
Fu, H., McDaniel, R., Hopwood, D. A., and Khosla, C. (1994) Engineered biosynthesis of novel polyketides: Stereochemical course of two reactions catalyzed by a polyketide synthase, Biochemistry 33, 9321-9326.
-
(1994)
Biochemistry
, vol.33
, pp. 9321-9326
-
-
Fu, H.1
McDaniel, R.2
Hopwood, D.A.3
Khosla, C.4
-
4
-
-
0032511416
-
Engineered biosynthesis of novel polyketides from Streptomyces spore pigment polyketide synthases
-
Yu, T.-W., Shen, Y., McDaniel, R., Floss, H. G., Khosla, C., Hopwood, D. A., and Moore, B. S. (1998) Engineered biosynthesis of novel polyketides from Streptomyces spore pigment polyketide synthases, J. Am. Chem. Soc. 120, 7749-7759.
-
(1998)
J. Am. Chem. Soc
, vol.120
, pp. 7749-7759
-
-
Yu, T.-W.1
Shen, Y.2
McDaniel, R.3
Floss, H.G.4
Khosla, C.5
Hopwood, D.A.6
Moore, B.S.7
-
5
-
-
0033616804
-
Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes
-
Shen, Y., Yoon, P., Yu, T.-W., Floss, H. G., Hopwood, D. A., and Moore, B. S. (1999) Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes, Proc. Natl. Acad. Sci. U.S.A. 96, 3622-3627.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 3622-3627
-
-
Shen, Y.1
Yoon, P.2
Yu, T.-W.3
Floss, H.G.4
Hopwood, D.A.5
Moore, B.S.6
-
6
-
-
0027970295
-
Engineered biosynthesis of novel polyketides: Influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase
-
McDaniel, R., Ebert-Khosla, S., Fu, H., Hopwood, D. A., and Khosla, C. (1994) Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase, Proc. Natl. Acad. Sci. U.S.A. 91, 11542-11546.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A
, vol.91
, pp. 11542-11546
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Fu, H.3
Hopwood, D.A.4
Khosla, C.5
-
7
-
-
0028242645
-
Engineered biosynthesis of novel polyketides: Dissection of the catalytic specificity of the act ketoreductase
-
Fu, H., Ebert-Khosla, S., Hopwood, D. A., and Khosla, C. (1994) Engineered biosynthesis of novel polyketides: dissection of the catalytic specificity of the act ketoreductase, J. Am. Chem. Soc. 116, 4166-4170.
-
(1994)
J. Am. Chem. Soc
, vol.116
, pp. 4166-4170
-
-
Fu, H.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
8
-
-
0029054128
-
Engineered biosynthesis of novel polyketides: Analysis of TcmN function in tetracenomycin biosynthesis
-
McDaniel, R., Hutchinson, C. R., and Khosla, C. (1995) Engineered biosynthesis of novel polyketides: analysis of TcmN function in tetracenomycin biosynthesis, J. Am. Chem. Soc. 117, 6805-6810.
-
(1995)
J. Am. Chem. Soc
, vol.117
, pp. 6805-6810
-
-
McDaniel, R.1
Hutchinson, C.R.2
Khosla, C.3
-
9
-
-
0031047160
-
Rational design and engineered biosynthesis of a novel 18-carbon aromatic polyketide
-
Kramer, P. J., Zawada, R. J. X., McDaniel, R., Hutchinson, C. R., Hopwood, D. A., and Khosla, C. (1997) Rational design and engineered biosynthesis of a novel 18-carbon aromatic polyketide. J. Am. Chem. Soc. 119, 635-639.
-
(1997)
J. Am. Chem. Soc
, vol.119
, pp. 635-639
-
-
Kramer, P.J.1
Zawada, R.J.X.2
McDaniel, R.3
Hutchinson, C.R.4
Hopwood, D.A.5
Khosla, C.6
-
10
-
-
0029064652
-
Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits
-
McDaniel, R., Ebert-Khosla, S., Hopwood, D. A., and Khosla, C. (1995) Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits, Nature 375, 549-554.
-
(1995)
Nature
, vol.375
, pp. 549-554
-
-
McDaniel, R.1
Ebert-Khosla, S.2
Hopwood, D.A.3
Khosla, C.4
-
11
-
-
0001081027
-
A one-pot condensation of pyrones and enals. Synthesis of 1H,7H-5a,6,8,9- tetrahydro-1-oxopyrano[4,3-b][1] benzopyrans
-
Hua, D. H., Chen, Y., Sin, H.-S., Maroto, M. J., Robinson, P. D., Newell, S. W., Perchellet, E. M., Ladesich, J. B., Freeman, J. A., Perchellet, J.-P., and Chiang, P. K. (1997) A one-pot condensation of pyrones and enals. Synthesis of 1H,7H-5a,6,8,9- tetrahydro-1-oxopyrano[4,3-b][1] benzopyrans, J. Org. Chem. 62. 6888-6896.
-
(1997)
J. Org. Chem
, vol.62
, pp. 6888-6896
-
-
Hua, D.H.1
Chen, Y.2
Sin, H.-S.3
Maroto, M.J.4
Robinson, P.D.5
Newell, S.W.6
Perchellet, E.M.7
Ladesich, J.B.8
Freeman, J.A.9
Perchellet, J.-P.10
Chiang, P.K.11
-
12
-
-
0037424327
-
A formal [3 + 3] cycloaddition reaction. Improved reactivity using α,β FPRIVATE-unsaturated iminium salts and evidence for reversibility of 6-electron electrocyclic ring closure of 1-oxatrienes
-
Shen, H. C., Wang, J., Cole, K. P., McLaughlin, M. J., Morgan, C. D., Douglas, C. J., Hsung, R. P., Coverdale, H. A., Gerasyuto, A. I., Hahn, J. M., Liu, J., Sklenicka, H. M., Wei, L.-L., Zehnder, L. R., and Zificsak, C. A. (2002) A formal [3 + 3] cycloaddition reaction. Improved reactivity using α,β FPRIVATE-unsaturated iminium salts and evidence for reversibility of 6-electron electrocyclic ring closure of 1-oxatrienes, J. Org. Chem. 68, 1729-1735.
-
(2002)
J. Org. Chem
, vol.68
, pp. 1729-1735
-
-
Shen, H.C.1
Wang, J.2
Cole, K.P.3
McLaughlin, M.J.4
Morgan, C.D.5
Douglas, C.J.6
Hsung, R.P.7
Coverdale, H.A.8
Gerasyuto, A.I.9
Hahn, J.M.10
Liu, J.11
Sklenicka, H.M.12
Wei, L.-L.13
Zehnder, L.R.14
Zificsak, C.A.15
-
13
-
-
2442665327
-
A modular and concise total synthesis of (±)-daurichromenic acid and analogues
-
Hu, H., Harrison, T. J., and Wilson, P. D. (2004) A modular and concise total synthesis of (±)-daurichromenic acid and analogues, J. Org. Chem. 69, 3782-3786.
-
(2004)
J. Org. Chem
, vol.69
, pp. 3782-3786
-
-
Hu, H.1
Harrison, T.J.2
Wilson, P.D.3
-
14
-
-
12344268799
-
Microwave assisted domino knoevenagel condensation/6-electron electrocyclization reactions for the rapid and efficient synthesis of substituted 2H,5H-pyrano[4,3-b]pyran-5-ones and related heterocycles
-
Leutbecher, H., Conrad, J., Klaiber, I., and Beifuss, U. (2004) Microwave assisted domino knoevenagel condensation/6-electron electrocyclization reactions for the rapid and efficient synthesis of substituted 2H,5H-pyrano[4,3-b]pyran-5-ones and related heterocycles, QSAR Comb. Sci. 23, 895-898.
-
(2004)
QSAR Comb. Sci
, vol.23
, pp. 895-898
-
-
Leutbecher, H.1
Conrad, J.2
Klaiber, I.3
Beifuss, U.4
-
15
-
-
0030877708
-
Antitumor activity of novel tricyclic pyrone analogs in murine leukemia cells in vitro
-
Perchellet, J.-P., Newell, S. W., Ladesich, J. B., Perchellet, E. M., Chen, Y., Hua, D. H., Kraft, S. L., Basaraba, R. J., Omura, S., and Tomoda, H. (1997) Antitumor activity of novel tricyclic pyrone analogs in murine leukemia cells in vitro, Anticancer Res. 17, 2427-2434.
-
(1997)
Anticancer Res
, vol.17
, pp. 2427-2434
-
-
Perchellet, J.-P.1
Newell, S.W.2
Ladesich, J.B.3
Perchellet, E.M.4
Chen, Y.5
Hua, D.H.6
Kraft, S.L.7
Basaraba, R.J.8
Omura, S.9
Tomoda, H.10
-
16
-
-
0031846864
-
Antitumor activity of tricyclic pyrone analogs, a new synthetic class of microtubule de-stabilizing agents, in the murine EMT-6 mammary tumor cell line in vitro
-
Perchellet, E. M., Ladesich, J. B., Chen, Y., Sin, H.-S., Hua, D. H., Kraft, S. L., and Perchellet, J.-P. (1998) Antitumor activity of tricyclic pyrone analogs, a new synthetic class of microtubule de-stabilizing agents, in the murine EMT-6 mammary tumor cell line in vitro, Anti-Cancer Drugs 9, 565-576.
-
(1998)
Anti-Cancer Drugs
, vol.9
, pp. 565-576
-
-
Perchellet, E.M.1
Ladesich, J.B.2
Chen, Y.3
Sin, H.-S.4
Hua, D.H.5
Kraft, S.L.6
Perchellet, J.-P.7
-
17
-
-
0033408395
-
Tricyclic pyrone analogs: A new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo
-
Perchellet, E. M., Ladesich, J. B., Magill, M. J., Chen, Y., Hua, D. H., and Perchellet, J.-P. (1999) Tricyclic pyrone analogs: a new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo, Anti-Cancer Drugs 10, 489-504.
-
(1999)
Anti-Cancer Drugs
, vol.10
, pp. 489-504
-
-
Perchellet, E.M.1
Ladesich, J.B.2
Magill, M.J.3
Chen, Y.4
Hua, D.H.5
Perchellet, J.-P.6
-
18
-
-
0025310579
-
Mutactin, a novel polyketide from Streptomyces coeli-color. Structure and biosynthetic relationship to actinorhodin
-
Zhang, H.-I., Adefarati, A., Gallucci, J., Cole, S. P., Beale, J. M., Keller, P. J., and Floss, H. G. (1990) Mutactin, a novel polyketide from Streptomyces coeli-color. Structure and biosynthetic relationship to actinorhodin, J. Org. Chem. 55, 1682-1684.
-
(1990)
J. Org. Chem
, vol.55
, pp. 1682-1684
-
-
Zhang, H.-I.1
Adefarati, A.2
Gallucci, J.3
Cole, S.P.4
Beale, J.M.5
Keller, P.J.6
Floss, H.G.7
-
19
-
-
18044393059
-
Diastereoselective annulation of 4-hydroxypyran-2H-ones with enantiopure 2,3-dideoxy-alpha,beta-unsaturated sugar aldehydes derived from respective glycals
-
Sagar, R., Singh, P., Kumar, R., Maulick, P. R., and Shaw, A. K. (2005) Diastereoselective annulation of 4-hydroxypyran-2H-ones with enantiopure 2,3-dideoxy-alpha,beta-unsaturated sugar aldehydes derived from respective glycals. Carbohydr. Res. 340, 1287-1300.
-
(2005)
Carbohydr. Res
, vol.340
, pp. 1287-1300
-
-
Sagar, R.1
Singh, P.2
Kumar, R.3
Maulick, P.R.4
Shaw, A.K.5
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