메뉴 건너뛰기




Volumn 122, Issue 4, 2010, Pages 239-252

Effects of valproate and carbamazepine monotherapy on neuroactive steroids, their precursors and metabolites in adult men with epilepsy

Author keywords

Androstanes; Carbamazepine; Epilepsy; GC MS; Neuroactive steroids; Pregnanolone isomers; Valproate

Indexed keywords

17 HYDROXYPREGNENOLONE; 20ALPHA DIHYDROPROGESTERONE; 5ALPHA,20ALPHA TETRAHYDROPROGESTERONE; 7BETA HYDROXY PRASTERONE; ANDROGEN; ANDROSTANEDIOL; ANDROSTANOLONE; ANDROSTENEDIOL; ANDROSTERONE; CARBAMAZEPINE; ELTANOLONE; EPIANDROSTERONE; GONADOTROPIN; HYDROCORTISONE; HYDROXYPROGESTERONE; ISOPREGNANOLONE; PRASTERONE; PREGN 5 ENE 3BETA,20ALPHA DIOL; PREGNENOLONE; PROGESTERONE; SEX HORMONE BINDING GLOBULIN; STEROID; TESTOSTERONE; UNCLASSIFIED DRUG; VALPROIC ACID; ANDROSTANE DERIVATIVE; ANTICONVULSIVE AGENT;

EID: 77957267976     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2010.06.003     Document Type: Article
Times cited : (19)

References (67)
  • 1
    • 76749136603 scopus 로고    scopus 로고
    • Peripheral neuroactive steroids may be as good as the steroids in the cerebrospinal fluid for the diagnostics of CNS disturbances
    • Kancheva R., Hill M., Novak Z., Chrastina J., Velikova M., Kancheva L., Riha I., Starka L. Peripheral neuroactive steroids may be as good as the steroids in the cerebrospinal fluid for the diagnostics of CNS disturbances. J. Steroid Biochem. Mol. Biol. 2010, 119(1-2):35-44.
    • (2010) J. Steroid Biochem. Mol. Biol. , vol.119 , Issue.1-2 , pp. 35-44
    • Kancheva, R.1    Hill, M.2    Novak, Z.3    Chrastina, J.4    Velikova, M.5    Kancheva, L.6    Riha, I.7    Starka, L.8
  • 2
    • 0030612193 scopus 로고    scopus 로고
    • 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-5alpha-pregnane-20-one in specific regions of the human female brain in different endocrine states
    • Bixo M., Andersson A., Winblad B., Purdy R.H., Backstrom T., Progesterone 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-5alpha-pregnane-20-one in specific regions of the human female brain in different endocrine states. Brain Res. 1997, 764(1-2):173-178.
    • (1997) Brain Res. , vol.764 , Issue.1-2 , pp. 173-178
    • Bixo, M.1    Andersson, A.2    Winblad, B.3    Purdy, R.H.4    Backstrom, T.5    Progesterone6
  • 3
    • 0031030995 scopus 로고    scopus 로고
    • Steroid hormones and excitability in the mammalian brain
    • Joels M. Steroid hormones and excitability in the mammalian brain. Front. Neuroendocrinol. 1997, 18(1):2-48.
    • (1997) Front. Neuroendocrinol. , vol.18 , Issue.1 , pp. 2-48
    • Joels, M.1
  • 4
    • 0034084485 scopus 로고    scopus 로고
    • Current issues on epileptic women
    • Pimentel J. Current issues on epileptic women. Curr. Pharm. Des. 2000, 6(8):865-872.
    • (2000) Curr. Pharm. Des. , vol.6 , Issue.8 , pp. 865-872
    • Pimentel, J.1
  • 5
    • 0037293399 scopus 로고    scopus 로고
    • Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties
    • Rupprecht R. Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties. Psychoneuroendocrinology 2003, 28(2):139-168.
    • (2003) Psychoneuroendocrinology , vol.28 , Issue.2 , pp. 139-168
    • Rupprecht, R.1
  • 7
    • 0033546993 scopus 로고    scopus 로고
    • Epilepsy in women: the science of why it is special
    • Morrell M.J. Epilepsy in women: the science of why it is special. Neurology 1999, 53(4 Suppl. 1):S42-S48.
    • (1999) Neurology , vol.53 , Issue.4 SUPPL. 1
    • Morrell, M.J.1
  • 8
    • 0345151831 scopus 로고    scopus 로고
    • Steroid hormones affect limbic afterdischarge thresholds and kindling rates in adult female rats
    • Edwards H.E., Burnham W.M., Mendonca A., Bowlby D.A., MacLusky N.J. Steroid hormones affect limbic afterdischarge thresholds and kindling rates in adult female rats. Brain Res. 1999, 838(1-2):136-150.
    • (1999) Brain Res. , vol.838 , Issue.1-2 , pp. 136-150
    • Edwards, H.E.1    Burnham, W.M.2    Mendonca, A.3    Bowlby, D.A.4    MacLusky, N.J.5
  • 9
    • 0345583682 scopus 로고    scopus 로고
    • Testosterone and its metabolites affect afterdischarge thresholds and the development of amygdala kindled seizures
    • Edwards H.E., Burnham W.M., MacLusky N.J. Testosterone and its metabolites affect afterdischarge thresholds and the development of amygdala kindled seizures. Brain Res. 1999, 838(1-2):151-157.
    • (1999) Brain Res. , vol.838 , Issue.1-2 , pp. 151-157
    • Edwards, H.E.1    Burnham, W.M.2    MacLusky, N.J.3
  • 10
    • 0038281536 scopus 로고    scopus 로고
    • Estradiol exerts neuroprotective actions against ischemic brain injury: insights derived from animal models
    • Wise P. Estradiol exerts neuroprotective actions against ischemic brain injury: insights derived from animal models. Endocrine 2003, 21(1):11-15.
    • (2003) Endocrine , vol.21 , Issue.1 , pp. 11-15
    • Wise, P.1
  • 11
    • 0033586349 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage
    • Bastianetto S., Ramassamy C., Poirier J., Quirion R. Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage. Brain Res. Mol. Brain Res. 1999, 66(1-2):35-41.
    • (1999) Brain Res. Mol. Brain Res. , vol.66 , Issue.1-2 , pp. 35-41
    • Bastianetto, S.1    Ramassamy, C.2    Poirier, J.3    Quirion, R.4
  • 12
    • 0032498644 scopus 로고    scopus 로고
    • Neuroprotection by dehydroepiandrosterone-sulfate: role of an NFkappaB-like factor
    • Mao X., Barger S.W. Neuroprotection by dehydroepiandrosterone-sulfate: role of an NFkappaB-like factor. Neuroreport 1998, 9(4):759-763.
    • (1998) Neuroreport , vol.9 , Issue.4 , pp. 759-763
    • Mao, X.1    Barger, S.W.2
  • 13
    • 0035162296 scopus 로고    scopus 로고
    • Metabolism of dehydroepiandrosterone by rat hippocampal cells in culture: possible role of aromatization and 7-hydroxylation in neuroprotection
    • Jellinck P.H., Lee S.J., McEwen B.S. Metabolism of dehydroepiandrosterone by rat hippocampal cells in culture: possible role of aromatization and 7-hydroxylation in neuroprotection. J. Steroid Biochem. Mol. Biol. 2001, 78(4):313-317.
    • (2001) J. Steroid Biochem. Mol. Biol. , vol.78 , Issue.4 , pp. 313-317
    • Jellinck, P.H.1    Lee, S.J.2    McEwen, B.S.3
  • 14
    • 0035225988 scopus 로고    scopus 로고
    • Neurosteroid 7-hydroxylation products in the brain
    • Morfin R., Starka L. Neurosteroid 7-hydroxylation products in the brain. Int. Rev. Neurobiol. 2001, 46:79-95.
    • (2001) Int. Rev. Neurobiol. , vol.46 , pp. 79-95
    • Morfin, R.1    Starka, L.2
  • 15
    • 53649088773 scopus 로고    scopus 로고
    • Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons
    • Leskiewicz M., Jantas D., Budziszewska B., Lason W. Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons. J. Physiol. Pharmacol. 2008, 59(3):457-475.
    • (2008) J. Physiol. Pharmacol. , vol.59 , Issue.3 , pp. 457-475
    • Leskiewicz, M.1    Jantas, D.2    Budziszewska, B.3    Lason, W.4
  • 16
    • 0032563651 scopus 로고    scopus 로고
    • Pregnenolone sulfate exacerbates NMDA-induced death of hippocampal neurons
    • Weaver C.E., Wu F.S., Gibbs T.T., Farb D.H. Pregnenolone sulfate exacerbates NMDA-induced death of hippocampal neurons. Brain Res. 1998, 803(1-2):129-136.
    • (1998) Brain Res. , vol.803 , Issue.1-2 , pp. 129-136
    • Weaver, C.E.1    Wu, F.S.2    Gibbs, T.T.3    Farb, D.H.4
  • 17
    • 20444446379 scopus 로고    scopus 로고
    • Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons
    • Shirakawa H., Katsuki H., Kume T., Kaneko S., Akaike A. Pregnenolone sulphate attenuates AMPA cytotoxicity on rat cortical neurons. Eur. J. Neurosci. 2005, 21(9):2329-2335.
    • (2005) Eur. J. Neurosci. , vol.21 , Issue.9 , pp. 2329-2335
    • Shirakawa, H.1    Katsuki, H.2    Kume, T.3    Kaneko, S.4    Akaike, A.5
  • 18
    • 0032253263 scopus 로고    scopus 로고
    • Hormonal effects on epilepsy in women
    • Klein P., Herzog A.G. Hormonal effects on epilepsy in women. Epilepsia 1998, 39(Suppl. 8):S9-S16.
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 8
    • Klein, P.1    Herzog, A.G.2
  • 19
    • 0028973110 scopus 로고
    • The neurosteroid 3 alpha, 5 alpha-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy
    • Frye C.A. The neurosteroid 3 alpha, 5 alpha-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy. Brain Res. 1995, 696(1-2):113-120.
    • (1995) Brain Res. , vol.696 , Issue.1-2 , pp. 113-120
    • Frye, C.A.1
  • 20
    • 1542327569 scopus 로고    scopus 로고
    • Anticonvulsant activity of the testosterone-derived neurosteroid 3alpha-androstanediol
    • Reddy D.S. Anticonvulsant activity of the testosterone-derived neurosteroid 3alpha-androstanediol. Neuroreport 2004, 15(3):515-518.
    • (2004) Neuroreport , vol.15 , Issue.3 , pp. 515-518
    • Reddy, D.S.1
  • 21
    • 20544469822 scopus 로고    scopus 로고
    • Anticonvulsant activity of androsterone and etiocholanolone
    • Kaminski R.M., Marini H., Kim W.J., Rogawski M.A. Anticonvulsant activity of androsterone and etiocholanolone. Epilepsia 2005, 46(6):819-827.
    • (2005) Epilepsia , vol.46 , Issue.6 , pp. 819-827
    • Kaminski, R.M.1    Marini, H.2    Kim, W.J.3    Rogawski, M.A.4
  • 23
    • 0033614716 scopus 로고    scopus 로고
    • Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites
    • Park-Chung M., Malayev A., Purdy R.H., Gibbs T.T., Farb D.H. Sulfated and unsulfated steroids modulate gamma-aminobutyric acidA receptor function through distinct sites. Brain Res. 1999, 830(1):72-87.
    • (1999) Brain Res. , vol.830 , Issue.1 , pp. 72-87
    • Park-Chung, M.1    Malayev, A.2    Purdy, R.H.3    Gibbs, T.T.4    Farb, D.H.5
  • 24
    • 0038397543 scopus 로고    scopus 로고
    • Inter-ictal and post-ictal circulating levels of allopregnanolone, an anticonvulsant metabolite of progesterone, in epileptic children
    • Grosso S., Luisi S., Mostardini R., Farnetani M., Cobellis L., Morgese G., Balestri P., Petraglia F. Inter-ictal and post-ictal circulating levels of allopregnanolone, an anticonvulsant metabolite of progesterone, in epileptic children. Epilepsy Res. 2003, 54(1):29-34.
    • (2003) Epilepsy Res. , vol.54 , Issue.1 , pp. 29-34
    • Grosso, S.1    Luisi, S.2    Mostardini, R.3    Farnetani, M.4    Cobellis, L.5    Morgese, G.6    Balestri, P.7    Petraglia, F.8
  • 25
    • 0035097212 scopus 로고    scopus 로고
    • Circulating levels of allopregnanolone, an anticonvulsant metabolite of progesterone, in women with partial epilepsy in the postcritical phase
    • Galli R, Luisi M., Pizzanelli C., Monteleone P., Casarosa E., Iudice A., Murri L. Circulating levels of allopregnanolone, an anticonvulsant metabolite of progesterone, in women with partial epilepsy in the postcritical phase. Epilepsia 2001, 42(2):216-219.
    • (2001) Epilepsia , vol.42 , Issue.2 , pp. 216-219
    • Galli, R.1    Luisi, M.2    Pizzanelli, C.3    Monteleone, P.4    Casarosa, E.5    Iudice, A.6    Murri, L.7
  • 26
    • 62949147212 scopus 로고    scopus 로고
    • Hormonal therapies: progesterone
    • Herzog A.G. Hormonal therapies: progesterone. Neurotherapeutics 2009, 6(2):383-391.
    • (2009) Neurotherapeutics , vol.6 , Issue.2 , pp. 383-391
    • Herzog, A.G.1
  • 27
    • 67349176702 scopus 로고    scopus 로고
    • The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy
    • Reddy D.S. The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy. Epilepsy Res. 2009, 85(1):1-30.
    • (2009) Epilepsy Res. , vol.85 , Issue.1 , pp. 1-30
    • Reddy, D.S.1
  • 28
    • 63149166858 scopus 로고    scopus 로고
    • Neurosteroid replacement therapy for catamenial epilepsy
    • Reddy D.S., Rogawski M.A. Neurosteroid replacement therapy for catamenial epilepsy. Neurotherapeutics 2009, 6(2):392-401.
    • (2009) Neurotherapeutics , vol.6 , Issue.2 , pp. 392-401
    • Reddy, D.S.1    Rogawski, M.A.2
  • 29
    • 33744473771 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone receptor expression on normal and tumorous human adrenocortical cells
    • Willenberg H.S., Haase M., Papewalis C., Schott M., Scherbaum W.A., Bornstein S.R. Corticotropin-releasing hormone receptor expression on normal and tumorous human adrenocortical cells. Neuroendocrinology 2005, 82(5-6):274-281.
    • (2005) Neuroendocrinology , vol.82 , Issue.5-6 , pp. 274-281
    • Willenberg, H.S.1    Haase, M.2    Papewalis, C.3    Schott, M.4    Scherbaum, W.A.5    Bornstein, S.R.6
  • 30
    • 0345425063 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone as adrenal androgen secretagogue
    • Ibanez L., Potau N., Marcos M.V., de Zegher F. Corticotropin-releasing hormone as adrenal androgen secretagogue. Pediatr. Res. 1999, 46(3):351-353.
    • (1999) Pediatr. Res. , vol.46 , Issue.3 , pp. 351-353
    • Ibanez, L.1    Potau, N.2    Marcos, M.V.3    de Zegher, F.4
  • 31
    • 0031758810 scopus 로고    scopus 로고
    • Corticotropin-releasing hormone directly and preferentially stimulates dehydroepiandrosterone sulfate secretion by human fetal adrenal cortical cells
    • Smith R., Mesiano S., Chan E.C., Brown S., Jaffe R.B. Corticotropin-releasing hormone directly and preferentially stimulates dehydroepiandrosterone sulfate secretion by human fetal adrenal cortical cells. J. Clin. Endocrinol. Metab. 1998, 83(8):2916-2920.
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , Issue.8 , pp. 2916-2920
    • Smith, R.1    Mesiano, S.2    Chan, E.C.3    Brown, S.4    Jaffe, R.B.5
  • 32
    • 0030926557 scopus 로고    scopus 로고
    • Developmental and functional biology of the primate fetal adrenal cortex
    • Mesiano S., Jaffe R.B. Developmental and functional biology of the primate fetal adrenal cortex. Endocr. Rev. 1997, 18(3):378-403.
    • (1997) Endocr. Rev. , vol.18 , Issue.3 , pp. 378-403
    • Mesiano, S.1    Jaffe, R.B.2
  • 33
    • 11144343250 scopus 로고    scopus 로고
    • The human fetal adrenal: making adrenal androgens for placental estrogens
    • Rainey W.E., Rehman K.S., Carr B.R. The human fetal adrenal: making adrenal androgens for placental estrogens. Semin. Reprod. Med. 2004, 22(4):327-336.
    • (2004) Semin. Reprod. Med. , vol.22 , Issue.4 , pp. 327-336
    • Rainey, W.E.1    Rehman, K.S.2    Carr, B.R.3
  • 35
    • 38349187871 scopus 로고    scopus 로고
    • Mass spectrometric assay and physiological-pharmacological activity of androgenic neurosteroids
    • Reddy D.S. Mass spectrometric assay and physiological-pharmacological activity of androgenic neurosteroids. Neurochem. Int. 2008, 52(4-5):541-553.
    • (2008) Neurochem. Int. , vol.52 , Issue.4-5 , pp. 541-553
    • Reddy, D.S.1
  • 36
    • 0030748614 scopus 로고    scopus 로고
    • Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology
    • Labrie F., Belanger A., Cusan L., Candas B. Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology. J. Clin. Endocrinol. Metab. 1997, 82(8):2403-2409.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , Issue.8 , pp. 2403-2409
    • Labrie, F.1    Belanger, A.2    Cusan, L.3    Candas, B.4
  • 38
    • 35148875149 scopus 로고    scopus 로고
    • Reversible effects of antiepileptic drugs on reproductive endocrine function in men and women with epilepsy-a prospective randomized double-blind withdrawal study
    • Lossius M.I., Tauboll E., Mowinckel P., Morkrid L., Gjerstad L. Reversible effects of antiepileptic drugs on reproductive endocrine function in men and women with epilepsy-a prospective randomized double-blind withdrawal study. Epilepsia 2007, 48(10):1875-1882.
    • (2007) Epilepsia , vol.48 , Issue.10 , pp. 1875-1882
    • Lossius, M.I.1    Tauboll, E.2    Mowinckel, P.3    Morkrid, L.4    Gjerstad, L.5
  • 40
    • 3042776662 scopus 로고    scopus 로고
    • Differential effects of antiepileptic drugs on sexual function and reproductive hormones in men with epilepsy: interim analysis of a comparison between lamotrigine and enzyme-inducing antiepileptic drugs
    • Herzog A.G., Drislane F.W., Schomer D.L., Pennell P.B., Bromfield E.B., Kelly K.M., Farina E.L., Frye C.A. Differential effects of antiepileptic drugs on sexual function and reproductive hormones in men with epilepsy: interim analysis of a comparison between lamotrigine and enzyme-inducing antiepileptic drugs. Epilepsia 2004, 45(7):764-768.
    • (2004) Epilepsia , vol.45 , Issue.7 , pp. 764-768
    • Herzog, A.G.1    Drislane, F.W.2    Schomer, D.L.3    Pennell, P.B.4    Bromfield, E.B.5    Kelly, K.M.6    Farina, E.L.7    Frye, C.A.8
  • 43
    • 0023795149 scopus 로고
    • Circulating hormones and pituitary responsiveness in young epileptic men receiving long-term antiepileptic medication
    • Macphee G.J., Larkin J.G., Butler E., Beastall G.H., Brodie M.J. Circulating hormones and pituitary responsiveness in young epileptic men receiving long-term antiepileptic medication. Epilepsia 1988, 29(4):468-475.
    • (1988) Epilepsia , vol.29 , Issue.4 , pp. 468-475
    • Macphee, G.J.1    Larkin, J.G.2    Butler, E.3    Beastall, G.H.4    Brodie, M.J.5
  • 45
    • 63749090255 scopus 로고    scopus 로고
    • Effects of valproate or lamotrigine monotherapy on the reproductive endocrine and insulin-related metabolic profile in Chinese adults with epilepsy: a prospective randomized study
    • Kwan P., Yip F.P., Hui A.C., Leung H., Ng P.W., Hui K.F., Chan I.H., Chan M.H., Lam C.W. Effects of valproate or lamotrigine monotherapy on the reproductive endocrine and insulin-related metabolic profile in Chinese adults with epilepsy: a prospective randomized study. Epilepsy Behav. 2009, 14(4):610-616.
    • (2009) Epilepsy Behav. , vol.14 , Issue.4 , pp. 610-616
    • Kwan, P.1    Yip, F.P.2    Hui, A.C.3    Leung, H.4    Ng, P.W.5    Hui, K.F.6    Chan, I.H.7    Chan, M.H.8    Lam, C.W.9
  • 47
    • 0034864141 scopus 로고    scopus 로고
    • Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy
    • Stephen L.J, Kwan P., Shapiro D., Dominiczak M., Brodie M.J. Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy. Epilepsia 2001, 42(8):1002-1006.
    • (2001) Epilepsia , vol.42 , Issue.8 , pp. 1002-1006
    • Stephen, L.J.1    Kwan, P.2    Shapiro, D.3    Dominiczak, M.4    Brodie, M.J.5
  • 48
    • 0031737634 scopus 로고    scopus 로고
    • Serum sex hormones are altered in patients with chronic temporal lobe epilepsy receiving anticonvulsant medication
    • Stöffel-Wagner B., Bauer J., Flugel D., Brennemann W., Klingmuller D., Elger C.E. Serum sex hormones are altered in patients with chronic temporal lobe epilepsy receiving anticonvulsant medication. Epilepsia 1998, 39(11):1164-1173.
    • (1998) Epilepsia , vol.39 , Issue.11 , pp. 1164-1173
    • Stöffel-Wagner, B.1    Bauer, J.2    Flugel, D.3    Brennemann, W.4    Klingmuller, D.5    Elger, C.E.6
  • 51
    • 3042856688 scopus 로고    scopus 로고
    • Serum androgen levels and testicular structure during pubertal maturation in male subjects with epilepsy
    • Mikkonen K., Tapanainen P., Pakarinen A.J., Paivansalo M., Isojarvi J.I., Vainionpaa L.K. Serum androgen levels and testicular structure during pubertal maturation in male subjects with epilepsy. Epilepsia 2004, 45(7):769-776.
    • (2004) Epilepsia , vol.45 , Issue.7 , pp. 769-776
    • Mikkonen, K.1    Tapanainen, P.2    Pakarinen, A.J.3    Paivansalo, M.4    Isojarvi, J.I.5    Vainionpaa, L.K.6
  • 53
    • 0033051270 scopus 로고    scopus 로고
    • Elimination of cross-reactivity by addition of an excess of cross-reactant for radioimmunoassay of 17alpha-hydroxypregnenolone
    • Hill M., Hampl R., Lukac D., Lapcik O., Pouzar V., Sulcova J. Elimination of cross-reactivity by addition of an excess of cross-reactant for radioimmunoassay of 17alpha-hydroxypregnenolone. Steroids 1999, 64(5):341-355.
    • (1999) Steroids , vol.64 , Issue.5 , pp. 341-355
    • Hill, M.1    Hampl, R.2    Lukac, D.3    Lapcik, O.4    Pouzar, V.5    Sulcova, J.6
  • 55
    • 0036083139 scopus 로고    scopus 로고
    • Orthogonal projections to latent structure
    • Trygg J., Wold S. Orthogonal projections to latent structure. J. Chemometrics 2002, 16:119-128.
    • (2002) J. Chemometrics , vol.16 , pp. 119-128
    • Trygg, J.1    Wold, S.2
  • 57
    • 0028946561 scopus 로고
    • Carbamazepine, phenytoin, sex hormones, and sexual function in men with epilepsy
    • Isojarvi J.I, Repo M., Pakarinen A.J., Lukkarinen O., Myllyla V.V. Carbamazepine, phenytoin, sex hormones, and sexual function in men with epilepsy. Epilepsia 1995, 36(4):366-370.
    • (1995) Epilepsia , vol.36 , Issue.4 , pp. 366-370
    • Isojarvi, J.I.1    Repo, M.2    Pakarinen, A.J.3    Lukkarinen, O.4    Myllyla, V.V.5
  • 58
    • 67449103058 scopus 로고    scopus 로고
    • Free testosterone and free dihydrotestosterone throughout the life span of men
    • Starka L., Pospisilova H., Hill M. Free testosterone and free dihydrotestosterone throughout the life span of men. J. Steroid Biochem. Mol. Biol. 2009, 116(1-2):118-120.
    • (2009) J. Steroid Biochem. Mol. Biol. , vol.116 , Issue.1-2 , pp. 118-120
    • Starka, L.1    Pospisilova, H.2    Hill, M.3
  • 60
    • 0033026796 scopus 로고    scopus 로고
    • Psychoneuroendocrine aspects of temporolimbic epilepsy. Part I. Brain, reproductive steroids, and emotions
    • Herzog A.G. Psychoneuroendocrine aspects of temporolimbic epilepsy. Part I. Brain, reproductive steroids, and emotions. Psychosomatics 1999, 40(2):95-101.
    • (1999) Psychosomatics , vol.40 , Issue.2 , pp. 95-101
    • Herzog, A.G.1
  • 61
    • 0033038073 scopus 로고    scopus 로고
    • Psychoneuroendocrine aspects of temporolimbic epilepsy. Part II: epilepsy and reproductive steroids
    • Herzog A.G. Psychoneuroendocrine aspects of temporolimbic epilepsy. Part II: epilepsy and reproductive steroids. Psychosomatics 1999, 40(2):102-108.
    • (1999) Psychosomatics , vol.40 , Issue.2 , pp. 102-108
    • Herzog, A.G.1
  • 62
    • 0032899259 scopus 로고    scopus 로고
    • Antiepileptic drug therapy and sexual function in men with epilepsy
    • Duncan S., Blacklaw J., Beastall G.H., Brodie M.J. Antiepileptic drug therapy and sexual function in men with epilepsy. Epilepsia 1999, 40(2):197-204.
    • (1999) Epilepsia , vol.40 , Issue.2 , pp. 197-204
    • Duncan, S.1    Blacklaw, J.2    Beastall, G.H.3    Brodie, M.J.4
  • 63
  • 64
    • 0033860968 scopus 로고    scopus 로고
    • Dehydroepiandrosterone sulfate is neuroprotective in a reversible spinal cord ischemia model: possible involvement of GABA(A) receptors
    • discussion 1957
    • Lapchak P.A., Chapman D.F., Nunez S.Y., Zivin J.A. Dehydroepiandrosterone sulfate is neuroprotective in a reversible spinal cord ischemia model: possible involvement of GABA(A) receptors. Stroke 2000, 31(8):1953-1956. discussion 1957.
    • (2000) Stroke , vol.31 , Issue.8 , pp. 1953-1956
    • Lapchak, P.A.1    Chapman, D.F.2    Nunez, S.Y.3    Zivin, J.A.4
  • 65
    • 0036185532 scopus 로고    scopus 로고
    • Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids
    • Malayev A., Gibbs T.T., Farb D.H. Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids. Br. J. Pharmacol. 2002, 135(4):901-909.
    • (2002) Br. J. Pharmacol. , vol.135 , Issue.4 , pp. 901-909
    • Malayev, A.1    Gibbs, T.T.2    Farb, D.H.3
  • 66
    • 0028167701 scopus 로고
    • 3 alpha-Hydroxy-5 beta-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons
    • Park-Chung M., Wu F.S., Farb D.H. 3 alpha-Hydroxy-5 beta-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons. Mol. Pharmacol. 1994, 46(1):146-150.
    • (1994) Mol. Pharmacol. , vol.46 , Issue.1 , pp. 146-150
    • Park-Chung, M.1    Wu, F.S.2    Farb, D.H.3
  • 67
    • 0032971150 scopus 로고    scopus 로고
    • Effects of pregnanolone on behavioural parameters and the responses to GABA(A) receptor antagonists in the late gestation fetal sheep
    • Nicol M.B., Hirst J.J., Walker D. Effects of pregnanolone on behavioural parameters and the responses to GABA(A) receptor antagonists in the late gestation fetal sheep. Neuropharmacology 1999, 38(1):49-63.
    • (1999) Neuropharmacology , vol.38 , Issue.1 , pp. 49-63
    • Nicol, M.B.1    Hirst, J.J.2    Walker, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.