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Volumn 44, Issue 2-3, 2001, Pages 141-153

Neuroactive steroids and seizure susceptibility

Author keywords

Epilepsy; Neuroactive steroids; Neuronal excitability; Neurosteroids; Seizures

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID RECEPTOR; ANDROGEN; ANDROSTANEDIOL; ANDROSTANOLONE; CORTICOSTEROID; ESTROGEN; GLUCOCORTICOID; MEMBRANE RECEPTOR; MESSENGER RNA; MINERALOCORTICOID; PREGNENOLONE; PROGESTERONE; PROGESTERONE RECEPTOR; TESTOSTERONE; TRIPTORELIN;

EID: 0035022721     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(01)00194-2     Document Type: Article
Times cited : (98)

References (119)
  • 1
    • 0001986656 scopus 로고    scopus 로고
    • Effects of hormones on seizure expression
    • J. Jr. Engel, & T.A. Pedley. Philadelphia: Lippincott Raven
    • Bäckström T., Rosciszewska D. Effects of hormones on seizure expression. Engel J. Jr, Pedley T.A. Epilepsy: A Comprehensive Textbook. 1997;2003-2012 Lippincott Raven, Philadelphia.
    • (1997) Epilepsy: A Comprehensive Textbook , pp. 2003-2012
    • Bäckström, T.1    Rosciszewska, D.2
  • 2
    • 0021277889 scopus 로고
    • Effects of intravenous progesterone infusions on the epileptic discharge frequency in women with partial epilepsy
    • Bäckström T., Zetterlund B., Blom S., Romano M. Effects of intravenous progesterone infusions on the epileptic discharge frequency in women with partial epilepsy. Acta Neurol. Scand. 69:1984;240-248.
    • (1984) Acta Neurol. Scand. , vol.69 , pp. 240-248
    • Bäckström, T.1    Zetterlund, B.2    Blom, S.3    Romano, M.4
  • 3
    • 0025579196 scopus 로고
    • Steroids in relationship to epilepsy and anaesthesia
    • D. Chadwick, & K. Widdows. Chichester, UK: Wiley. Ciba Foundation Symposium 153
    • Bäckström T., Gee K.W., Lan N., Sörensen M., Wahlström G. Steroids in relationship to epilepsy and anaesthesia. Chadwick D., Widdows K. Steroids and Neuronal Activity. 1990;225-239 Wiley, Chichester, UK. Ciba Foundation Symposium 153.
    • (1990) Steroids and Neuronal Activity , pp. 225-239
    • Bäckström, T.1    Gee, K.W.2    Lan, N.3    Sörensen, M.4    Wahlström, G.5
  • 4
    • 0026520388 scopus 로고
    • The effect of a synthetic GnRH analogue on catamenial epilepsy: A study in ten patients
    • Bauer J., Wildt L., Flügel D., Stefan H. The effect of a synthetic GnRH analogue on catamenial epilepsy: a study in ten patients. J. Neurol. 239:1992;284-286.
    • (1992) J. Neurol. , vol.239 , pp. 284-286
    • Bauer, J.1    Wildt, L.2    Flügel, D.3    Stefan, H.4
  • 5
    • 0028886678 scopus 로고
    • Catamenial seizures: An analysis (in German)
    • Bauer J., Hocke A., Elger C.E. Catamenial seizures: an analysis (in German). Nervenarzt. 66:1995;760-769.
    • (1995) Nervenarzt , vol.66 , pp. 760-769
    • Bauer, J.1    Hocke, A.2    Elger, C.E.3
  • 6
    • 0031963645 scopus 로고    scopus 로고
    • Seizure occurrence during ovulatory and anovulatory cycles in patients with temporal lobe epilepsy: A prospective study
    • Bauer J., Burr W., Elger C.E. Seizure occurrence during ovulatory and anovulatory cycles in patients with temporal lobe epilepsy: a prospective study. Eur. J. Neurol. 5:1998;83-88.
    • (1998) Eur. J. Neurol. , vol.5 , pp. 83-88
    • Bauer, J.1    Burr, W.2    Elger, C.E.3
  • 7
    • 0032448780 scopus 로고    scopus 로고
    • Neurosteroids: A novel function of the brain
    • Baulieu E.E. Neurosteroids: a novel function of the brain. Psychoneuroendocrinology. 23:1998;963-987.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 963-987
    • Baulieu, E.E.1
  • 8
    • 0032745934 scopus 로고    scopus 로고
    • The female sex hormone oestrogen as a neuroprotectant
    • Behl C., Holsboer F. The female sex hormone oestrogen as a neuroprotectant. Trends Pharmacol. Sci. 20:1999;441-444.
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 441-444
    • Behl, C.1    Holsboer, F.2
  • 9
    • 0025161662 scopus 로고
    • Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride-ionophore complex
    • Belelli D., Lan N.C., Gee K.W. Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride-ionophore complex. Neurosci. Biobehav. Rev. 14:1990;315-322.
    • (1990) Neurosci. Biobehav. Rev. , vol.14 , pp. 315-322
    • Belelli, D.1    Lan, N.C.2    Gee, K.W.3
  • 10
    • 0030010448 scopus 로고    scopus 로고
    • Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: Effects mediated via sigma receptors
    • Bergeron R., de Montigny C., Debonnel G. Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors. J. Neurosci. 16:1996;1193-1202.
    • (1996) J. Neurosci. , vol.16 , pp. 1193-1202
    • Bergeron, R.1    De Montigny, C.2    Debonnel, G.3
  • 12
    • 0033883756 scopus 로고    scopus 로고
    • Expression of mRNAs encoding for 17β-hydroxisteroid dehydrogenase isozymes 1, 2, 3, and 4 in epileptic human hippocampus
    • Beyenburg S., Watzka M., Blümcke I., Schramm J., Bidlingmaier F., Elger C.E., Stoffel-Wagner B. Expression of mRNAs encoding for 17β-hydroxisteroid dehydrogenase isozymes 1, 2, 3, and 4 in epileptic human hippocampus. Epilepsy Res. 41:2000a;83-91.
    • (2000) Epilepsy Res. , vol.41 , pp. 83-91
    • Beyenburg, S.1    Watzka, M.2    Blümcke, I.3    Schramm, J.4    Bidlingmaier, F.5    Elger, C.E.6    Stoffel-Wagner, B.7
  • 14
    • 0030612193 scopus 로고    scopus 로고
    • Progesterone, 5α-pregnane-3,20-dione and 3α-hydroxy-5α-pregnane-20-one in specific regions of the human female brain in different endocrine states
    • Bixo M., Andersson A., Winblad B., Purdy R.H., Bäckström T. Progesterone, 5α-pregnane-3,20-dione and 3α-hydroxy-5α-pregnane-20-one in specific regions of the human female brain in different endocrine states. Brain Res. 764:1997;173-178.
    • (1997) Brain Res. , vol.764 , pp. 173-178
    • Bixo, M.1    Andersson, A.2    Winblad, B.3    Purdy, R.H.4    Bäckström, T.5
  • 15
    • 0032580092 scopus 로고    scopus 로고
    • Premenstrual steroids?
    • Britton K.T., Koob G.F. Premenstrual steroids? Nature. 392:1998;869-870.
    • (1998) Nature , vol.392 , pp. 869-870
    • Britton, K.T.1    Koob, G.F.2
  • 16
    • 0031720906 scopus 로고    scopus 로고
    • Selective changes in single cell GABA(A) receptor subunit expression and function in temporal lobe epilepsy
    • Brooks-Kayal A.R., Shumate M.D., Jin H., Rikhter T.Y., Coulter D.A. Selective changes in single cell GABA(A) receptor subunit expression and function in temporal lobe epilepsy. Nat. Med. 4:1998;1166-1172.
    • (1998) Nat. Med. , vol.4 , pp. 1166-1172
    • Brooks-Kayal, A.R.1    Shumate, M.D.2    Jin, H.3    Rikhter, T.Y.4    Coulter, D.A.5
  • 18
    • 0034019756 scopus 로고    scopus 로고
    • Glutamate and epilepsy
    • Chapman A.G. Glutamate and epilepsy. J. Nutr. 130:(4):2000;1043S-1045.
    • (2000) J. Nutr. , vol.130 , Issue.4
    • Chapman, A.G.1
  • 19
    • 0027433185 scopus 로고
    • How common is catamenial epilepsy?
    • Duncan S., Read C.L., Brodie M.J. How common is catamenial epilepsy? Epilepsia. 34:1993;827-831.
    • (1993) Epilepsia , vol.34 , pp. 827-831
    • Duncan, S.1    Read, C.L.2    Brodie, M.J.3
  • 20
    • 0029011707 scopus 로고
    • Hippocampal GABA transporter function in temporal lobe epilepsy
    • During M.J., Ryder K.M., Spencer D.D. Hippocampal GABA transporter function in temporal lobe epilepsy. Nature. 376:1995;174-177.
    • (1995) Nature , vol.376 , pp. 174-177
    • During, M.J.1    Ryder, K.M.2    Spencer, D.D.3
  • 21
    • 0345151831 scopus 로고    scopus 로고
    • Steroid hormones affect limbic afterdischarge thresholds and kindling rates in adult female rats
    • Edwards H.E., Burnham W.M., Mendonca A., Bowlby D.A., MacLusky N.J. Steroid hormones affect limbic afterdischarge thresholds and kindling rates in adult female rats. Brain Res. 838:1999a;136-150.
    • (1999) Brain Res. , vol.838 , pp. 136-150
    • Edwards, H.E.1    Burnham, W.M.2    Mendonca, A.3    Bowlby, D.A.4    MacLusky, N.J.5
  • 22
    • 0345583682 scopus 로고    scopus 로고
    • Testosterone and its metabolites affect afterdischarge thresholds and the development of amygdala kindled seizures
    • Edwards H.E., Burnham W.M., MacLusky N.J. Testosterone and its metabolites affect afterdischarge thresholds and the development of amygdala kindled seizures. Brain Res. 838:1999b;151-157.
    • (1999) Brain Res. , vol.838 , pp. 151-157
    • Edwards, H.E.1    Burnham, W.M.2    MacLusky, N.J.3
  • 23
    • 0028973110 scopus 로고
    • The neurosteroid 3α, 5α-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy
    • Frye C.A. The neurosteroid 3α, 5α-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy. Brain Res. 696:1995;113-120.
    • (1995) Brain Res. , vol.696 , pp. 113-120
    • Frye, C.A.1
  • 24
    • 0031870605 scopus 로고    scopus 로고
    • Androgenic neurosteroids: Anti-seizure effects in an animal model of epilepsy
    • Frye C.A., Reed T.A. Androgenic neurosteroids: anti-seizure effects in an animal model of epilepsy. Psychoneuroendocrinology. 23:1998;385-399.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 385-399
    • Frye, C.A.1    Reed, T.A.2
  • 25
    • 0030838076 scopus 로고    scopus 로고
    • Anticonvulsant and behavioral effects of neuroactive steroids alone and in conjunction with diazepam
    • Gasior M., Carter R.B., Goldberg S.R., Witkin J.M. Anticonvulsant and behavioral effects of neuroactive steroids alone and in conjunction with diazepam. J. Pharmacol. Exp. Ther. 282:1997;543-553.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 543-553
    • Gasior, M.1    Carter, R.B.2    Goldberg, S.R.3    Witkin, J.M.4
  • 26
    • 0032983002 scopus 로고    scopus 로고
    • Neuroactive steroids: Potential therapeutic use in neurological and psychiatric disorders
    • Gasior M., Carter R.B., Witkin J.M. Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders. Trends Pharmacol. Sci. 20:1999;107-112.
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 107-112
    • Gasior, M.1    Carter, R.B.2    Witkin, J.M.3
  • 27
    • 0034101871 scopus 로고    scopus 로고
    • Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure kindled-mice: Comparison with diazepam and valproate
    • Gasior M., Ungard J.T., Beekman M., Carter R.B., Witkin J.M. Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure kindled-mice: comparison with diazepam and valproate. Neuropharmacology. 39:2000;1184-1196.
    • (2000) Neuropharmacology , vol.39 , pp. 1184-1196
    • Gasior, M.1    Ungard, J.T.2    Beekman, M.3    Carter, R.B.4    Witkin, J.M.5
  • 28
    • 0028801074 scopus 로고
    • A receptor complex: The pharmacological properties and therapeutic potential of epalons
    • A receptor complex: the pharmacological properties and therapeutic potential of epalons. Crit. Rev. Neurobiol. 9:1995;207-227.
    • (1995) Crit. Rev. Neurobiol. , vol.9 , pp. 207-227
    • Gee, K.W.1    McCauley, L.D.2    Lan, N.C.3
  • 29
    • 2642672840 scopus 로고    scopus 로고
    • Inhibition of oxytocin receptor function by direct binding of progesterone
    • Grazzini E., Guillon G., Mouillac B., Zingg H.H. Inhibition of oxytocin receptor function by direct binding of progesterone. Nature. 392:1998;509-512.
    • (1998) Nature , vol.392 , pp. 509-512
    • Grazzini, E.1    Guillon, G.2    Mouillac, B.3    Zingg, H.H.4
  • 31
    • 0025719578 scopus 로고
    • Catamenial epilepsy and gosorelin (letter)
    • Haider Y., Barnett D.B. Catamenial epilepsy and gosorelin (letter). Lancet. 338:1991;1530.
    • (1991) Lancet , vol.338 , pp. 1530
    • Haider, Y.1    Barnett, D.B.2
  • 32
    • 0020700055 scopus 로고
    • Progesterone, androstene-dione, testosterone, 5α-dihydrotestosterone and androsterone concentrations in specific regions of the human brain
    • Hammond G.L., Hirvonen J., Vihko R. Progesterone, androstene-dione, testosterone, 5α-dihydrotestosterone and androsterone concentrations in specific regions of the human brain. J. Ster. Biochem. 18:1983;185-189.
    • (1983) J. Ster. Biochem. , vol.18 , pp. 185-189
    • Hammond, G.L.1    Hirvonen, J.2    Vihko, R.3
  • 34
    • 0023019152 scopus 로고
    • Intermittent progesterone therapy and frequency of complex partial seizures in women with menstrual disorders
    • Herzog A.G. Intermittent progesterone therapy and frequency of complex partial seizures in women with menstrual disorders. Neurology. 36:1986;1607-1610.
    • (1986) Neurology , vol.36 , pp. 1607-1610
    • Herzog, A.G.1
  • 35
    • 0023863062 scopus 로고
    • Clomiphene therapy in epileptic women with menstrual disorders
    • Herzog A.G. Clomiphene therapy in epileptic women with menstrual disorders. Neurology. 38:1988;432-434.
    • (1988) Neurology , vol.38 , pp. 432-434
    • Herzog, A.G.1
  • 36
    • 0025788057 scopus 로고
    • Reproductive endocrine considerations and hormonal therapy in men with epilepsy
    • Herzog A.G. Reproductive endocrine considerations and hormonal therapy in men with epilepsy. Epilepsia. 32:(6):1991;S34-S37.
    • (1991) Epilepsia , vol.32 , Issue.6 , pp. 34-S37
    • Herzog, A.G.1
  • 37
    • 0028810993 scopus 로고
    • Progesterone therapy in women with complex partial and secondary generalized seizures
    • Herzog A.G. Progesterone therapy in women with complex partial and secondary generalized seizures. Neurology. 45:1995;1660-1662.
    • (1995) Neurology , vol.45 , pp. 1660-1662
    • Herzog, A.G.1
  • 38
    • 0032975421 scopus 로고    scopus 로고
    • Progesterone therapy in women with epilepsy: A 3-year follow-up
    • Herzog A.G. Progesterone therapy in women with epilepsy: a 3-year follow-up. Neurology. 52:1999a;1917-1918.
    • (1999) Neurology , vol.52 , pp. 1917-1918
    • Herzog, A.G.1
  • 39
    • 0033026796 scopus 로고    scopus 로고
    • Psychoneuroendocrine aspects of temporolimbic epilepsy. Part I. Brain, reproductive steroids, and emotions
    • Herzog A.G. Psychoneuroendocrine aspects of temporolimbic epilepsy. Part I. Brain, reproductive steroids, and emotions. Psychosomatics. 40:1999b;95-101.
    • (1999) Psychosomatics , vol.40 , pp. 95-101
    • Herzog, A.G.1
  • 40
    • 0033038073 scopus 로고    scopus 로고
    • Psychoneuroendocrine aspects of temporolimbic epilepsy. Part II. Epilepsy and reproductive steroids
    • Herzog A.G. Psychoneuroendocrine aspects of temporolimbic epilepsy. Part II. Epilepsy and reproductive steroids. Psychosomatics. 40:1999c;102-108.
    • (1999) Psychosomatics , vol.40 , pp. 102-108
    • Herzog, A.G.1
  • 41
    • 0030866438 scopus 로고    scopus 로고
    • Three patterns of catamenial epilepsy
    • Herzog A.G., Klein P., Ransil B.J. Three patterns of catamenial epilepsy. Epilepsia. 38:1997;1082-1088.
    • (1997) Epilepsia , vol.38 , pp. 1082-1088
    • Herzog, A.G.1    Klein, P.2    Ransil, B.J.3
  • 42
    • 0031944515 scopus 로고    scopus 로고
    • Testosterone versus testolactone in treating reproductive and sexual dysfunction in men with epilepsy and hypogonadism
    • Herzog A.G., Klein P., Jacobs A.R. Testosterone versus testolactone in treating reproductive and sexual dysfunction in men with epilepsy and hypogonadism. Neurology. 50:1998;782-784.
    • (1998) Neurology , vol.50 , pp. 782-784
    • Herzog, A.G.1    Klein, P.2    Jacobs, A.R.3
  • 43
    • 84965087561 scopus 로고
    • Steroid-induced convulsions in experimental animals
    • Heuser E., Eidelberg E. Steroid-induced convulsions in experimental animals. Endocrinology. 69:1961;915-924.
    • (1961) Endocrinology , vol.69 , pp. 915-924
    • Heuser, E.1    Eidelberg, E.2
  • 44
    • 0031030995 scopus 로고    scopus 로고
    • Steroid hormones and excitability in the mammalian brain
    • Joels M. Steroid hormones and excitability in the mammalian brain. Front. Neuroendocrinol. 18:1997;2-48.
    • (1997) Front. Neuroendocrinol. , vol.18 , pp. 2-48
    • Joels, M.1
  • 45
    • 0025298244 scopus 로고
    • Mineralocorticoid receptor-mediated changes in membrane properties of rat CA1 pyramidal neurons in vitro
    • Joels M., de Kloet E.R. Mineralocorticoid receptor-mediated changes in membrane properties of rat CA1 pyramidal neurons in vitro. Proc. Natl. Acad. Sci. USA. 87:1990;4495-4498.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4495-4498
    • Joels, M.1    De Kloet, E.R.2
  • 46
    • 0142207398 scopus 로고    scopus 로고
    • Corticosteroids in the brain. Cellular and molecular actions
    • Joels M., Vreugdenhil E. Corticosteroids in the brain. Cellular and molecular actions. Mol. Neurobiol. 17:1998;87-108.
    • (1998) Mol. Neurobiol. , vol.17 , pp. 87-108
    • Joels, M.1    Vreugdenhil, E.2
  • 47
    • 0032967234 scopus 로고    scopus 로고
    • Episodic corticosterone treatment accelerates kindling epileptogenesis and triggers long-term changes in hippocampal CA1 cells, in the fully kindled state
    • Karst H., de Kloet E.R., Joels M. Episodic corticosterone treatment accelerates kindling epileptogenesis and triggers long-term changes in hippocampal CA1 cells, in the fully kindled state. Eur. J. Neurosci. 11:1999;889-898.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 889-898
    • Karst, H.1    De Kloet, E.R.2    Joels, M.3
  • 52
    • 0028149787 scopus 로고
    • Anticonvulsant activity of neurosteroids: Correlation with γ-aminobutyric acid-evoked chloride current potentiation
    • Kokate T.G., Svensson B.E., Rogawski M.A. Anticonvulsant activity of neurosteroids: Correlation with γ-aminobutyric acid-evoked chloride current potentiation. J. Pharmacol. Exp. Ther. 270:1994;1223-1229.
    • (1994) J. Pharmacol. Exp. Ther. , vol.270 , pp. 1223-1229
    • Kokate, T.G.1    Svensson, B.E.2    Rogawski, M.A.3
  • 54
    • 0032590065 scopus 로고    scopus 로고
    • Finasteride, a 5α-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice
    • Kokate T.G., Banks M.K., Magee T., Yamaguchi S., Rogawski M.A. Finasteride, a 5α-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice. J. Pharmacol. Exp. Ther. 288:1999;679-684.
    • (1999) J. Pharmacol. Exp. Ther. , vol.288 , pp. 679-684
    • Kokate, T.G.1    Banks, M.K.2    Magee, T.3    Yamaguchi, S.4    Rogawski, M.A.5
  • 55
    • 0023184862 scopus 로고
    • Simultaneous radioimmunoassay of progesterone, androst-4-enedione, pregnenolone, dehydroepiandrosterone and 17-hydroxyprogesterone in specific regions of human brain
    • Lacroix C., Fiett J., Benais J.-P., Gueux B., Bonete R., Villette J.-M., Gourmel B., Dreux C. Simultaneous radioimmunoassay of progesterone, androst-4-enedione, pregnenolone, dehydroepiandrosterone and 17-hydroxyprogesterone in specific regions of human brain. J. Ster. Biochem. 28:1987;317-325.
    • (1987) J. Ster. Biochem. , vol.28 , pp. 317-325
    • Lacroix, C.1    Fiett, J.2    Benais, J.-P.3    Gueux, B.4    Bonete, R.5    Villette, J.-M.6    Gourmel, B.7    Dreux, C.8
  • 57
    • 0023608657 scopus 로고
    • The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex
    • Landgren S., Aasly J., Bäckström T., Dubrovsky B., Danielsson E. The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex. Acta Physiol. Scand. 131:1987;33-42.
    • (1987) Acta Physiol. Scand. , vol.131 , pp. 33-42
    • Landgren, S.1    Aasly, J.2    Bäckström, T.3    Dubrovsky, B.4    Danielsson, E.5
  • 58
    • 0022975279 scopus 로고
    • Sex steroids and 5-en-3β-hydroxysteroids in specific regions of human brain and cranial nerves
    • Lanthier A., Patwardhan V.V. Sex steroids and 5-en-3β-hydroxysteroids in specific regions of human brain and cranial nerves. J. Ster. Biochem. 25:1986;445-449.
    • (1986) J. Ster. Biochem. , vol.25 , pp. 445-449
    • Lanthier, A.1    Patwardhan, V.V.2
  • 59
    • 0033821412 scopus 로고    scopus 로고
    • Assessment of ganaxolone's anticonvulsant activity using a randomized, double-blind, presurgical trial design. Ganaxolone Presurgical Study Group
    • Laxer K., Blum D., Abou-Khalil B.W., Morrell M.J., Lee D.A., Data J.L., Monaghan E.P. Assessment of ganaxolone's anticonvulsant activity using a randomized, double-blind, presurgical trial design. Ganaxolone Presurgical Study Group. Epilepsia. 41:2000;1187-1194.
    • (2000) Epilepsia , vol.41 , pp. 1187-1194
    • Laxer, K.1    Blum, D.2    Abou-Khalil, B.W.3    Morrell, M.J.4    Lee, D.A.5    Data, J.L.6    Monaghan, E.P.7
  • 60
    • 0027332117 scopus 로고
    • Brain 5α-reductase: Cellular, enzymatic, and molecular perspectives and implications for biological function
    • Lephart E.D. Brain 5α-reductase: Cellular, enzymatic, and molecular perspectives and implications for biological function. Mol. Cell. Neurosci. 4:1993;473-484.
    • (1993) Mol. Cell. Neurosci. , vol.4 , pp. 473-484
    • Lephart, E.D.1
  • 61
    • 0343810516 scopus 로고    scopus 로고
    • Effect of ganaxolone on furothyl seizures in developing rats
    • Liptakova S., Velisek L., Veliskova J., Moshe S.L. Effect of ganaxolone on furothyl seizures in developing rats. Epilepsia. 41:2000;788-793.
    • (2000) Epilepsia , vol.41 , pp. 788-793
    • Liptakova, S.1    Velisek, L.2    Veliskova, J.3    Moshe, S.L.4
  • 62
    • 0000381369 scopus 로고
    • Electrocortical activation by estrogens
    • Logothetis J., Harner R. Electrocortical activation by estrogens. Arch. Neurol. 3:1960;290-297.
    • (1960) Arch. Neurol. , vol.3 , pp. 290-297
    • Logothetis, J.1    Harner, R.2
  • 63
    • 84936907872 scopus 로고
    • The role of estrogens in catamenial exacerbation of epilepsy
    • Logothetis J., Harner R., Morrell F., Torres F. The role of estrogens in catamenial exacerbation of epilepsy. Neurology. 9:1959;352-360.
    • (1959) Neurology , vol.9 , pp. 352-360
    • Logothetis, J.1    Harner, R.2    Morrell, F.3    Torres, F.4
  • 64
    • 0026509649 scopus 로고
    • A receptor. Mechanism of action and physiological significance
    • A receptor. Mechanism of action and physiological significance. Prog. Neurobiol. 38:1992;379-395.
    • (1992) Prog. Neurobiol. , vol.38 , pp. 379-395
    • Majewska, M.D.1
  • 65
    • 0022483382 scopus 로고
    • Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
    • Majewska M.D., Harrison N.L., Schwartz R.D., Barker J.L., Paul S.M. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science. 232:1986;1004-1007.
    • (1986) Science , vol.232 , pp. 1004-1007
    • Majewska, M.D.1    Harrison, N.L.2    Schwartz, R.D.3    Barker, J.L.4    Paul, S.M.5
  • 67
    • 0030968187 scopus 로고    scopus 로고
    • Ovarian steroids and the brain: Implications for cognition and aging
    • McEwen B.S., Alves S.E., Bulloch K., Weiland N.G. Ovarian steroids and the brain: implications for cognition and aging. Neurology. 48:(7):1997;S8-S15.
    • (1997) Neurology , vol.48 , Issue.7 , pp. 8-S15
    • McEwen, B.S.1    Alves, S.E.2    Bulloch, K.3    Weiland, N.G.4
  • 68
    • 0028003285 scopus 로고
    • Neurosteroids: Biochemistry, modes of action, and clinical relevance
    • Mellon S.H. Neurosteroids: Biochemistry, modes of action, and clinical relevance. J. Clin. Endocrinol. Metab. 78:1994;1003-1008.
    • (1994) J. Clin. Endocrinol. Metab. , vol.78 , pp. 1003-1008
    • Mellon, S.H.1
  • 69
    • 0032956181 scopus 로고    scopus 로고
    • Neurosteroids: Expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system
    • Mensah-Nyagan A., Do-Rego J.L., Beaujean D., Luu-The V., Pelletier G., Vaudry H. Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system. Pharmacol. Rev. 51:1999;63-81.
    • (1999) Pharmacol. Rev. , vol.51 , pp. 63-81
    • Mensah-Nyagan, A.1    Do-Rego, J.L.2    Beaujean, D.3    Luu-The, V.4    Pelletier, G.5    Vaudry, H.6
  • 70
    • 0030869099 scopus 로고    scopus 로고
    • Initial human experience with ganaxolone, a neuroactive steroid with antiepileptic activity
    • Monaghan E.P., Navalta L.A., Shum L., Ashbrook D., Lee D.A. Initial human experience with ganaxolone, a neuroactive steroid with antiepileptic activity. Epilepsia. 38:1997a;1026-1031.
    • (1997) Epilepsia , vol.38 , pp. 1026-1031
    • Monaghan, E.P.1    Navalta, L.A.2    Shum, L.3    Ashbrook, D.4    Lee, D.A.5
  • 72
    • 0026448795 scopus 로고
    • Hormones and epilepsy through the lifetime
    • Morrell M.J. Hormones and epilepsy through the lifetime. Epilepsia. 33:(4):1992;S49-S61.
    • (1992) Epilepsia , vol.33 , Issue.4 , pp. 49-S61
    • Morrell, M.J.1
  • 73
    • 0033546993 scopus 로고    scopus 로고
    • Epilepsy in women: The science of why it is special
    • Morrell M.J. Epilepsy in women: the science of why it is special. Neurology. 53:(1):1999;S42-S48.
    • (1999) Neurology , vol.53 , Issue.1 , pp. 42-S48
    • Morrell, M.J.1
  • 74
    • 0029973815 scopus 로고    scopus 로고
    • Regulation of dendritic spine density in cultured rat hippocampal neurons by steroid hormones
    • Murphy D.D., Segal M. Regulation of dendritic spine density in cultured rat hippocampal neurons by steroid hormones. J. Neurosci. 16:1996;4059-4068.
    • (1996) J. Neurosci. , vol.16 , pp. 4059-4068
    • Murphy, D.D.1    Segal, M.2
  • 75
    • 0033761656 scopus 로고    scopus 로고
    • Progesterone prevents estradiol-induced dendritic spine formation in cultured hippocampal neurons
    • Murphy D.D., Segal M. Progesterone prevents estradiol-induced dendritic spine formation in cultured hippocampal neurons. Neuroendocrinology. 72:2000;133-143.
    • (2000) Neuroendocrinology , vol.72 , pp. 133-143
    • Murphy, D.D.1    Segal, M.2
  • 76
    • 0032053426 scopus 로고    scopus 로고
    • Estradiol increases dendritic spine density by reducing GABA neurotransmission in hippocampal neurons
    • Murphy D.D., Cole N.B., Greenberger V., Segal M. Estradiol increases dendritic spine density by reducing GABA neurotransmission in hippocampal neurons. J. Neurosci. 18:1998;2550-2559.
    • (1998) J. Neurosci. , vol.18 , pp. 2550-2559
    • Murphy, D.D.1    Cole, N.B.2    Greenberger, V.3    Segal, M.4
  • 77
    • 0026506016 scopus 로고
    • Guanyl nucleotides modulate binding to steroid receptors in neuronal membranes
    • Orchinik M., Murray T.F., Franklin P.H., Moore F.L. Guanyl nucleotides modulate binding to steroid receptors in neuronal membranes. Proc. Natl. Acad. Sci. USA. 89:1992;3830-3834.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3830-3834
    • Orchinik, M.1    Murray, T.F.2    Franklin, P.H.3    Moore, F.L.4
  • 78
    • 0026579057 scopus 로고
    • Neuroactive steroids
    • Paul S.M., Purdy R.H. Neuroactive steroids. FASEB J. 6:1992;2311-2322.
    • (1992) FASEB J. , vol.6 , pp. 2311-2322
    • Paul, S.M.1    Purdy, R.H.2
  • 79
    • 0034114905 scopus 로고    scopus 로고
    • The effects of epilepsy and its treatment on sexual and reproductive function
    • Penovich P.E. The effects of epilepsy and its treatment on sexual and reproductive function. Epilepsia. 41:(2):2000;S53-S61.
    • (2000) Epilepsia , vol.41 , Issue.2 , pp. 53-S61
    • Penovich, P.E.1
  • 80
    • 0033842656 scopus 로고    scopus 로고
    • Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy
    • Reddy D.S., Rogawski M.A. Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy. J. Pharmacol. Exp. Ther. 294:2000a;909-915.
    • (2000) J. Pharmacol. Exp. Ther. , vol.294 , pp. 909-915
    • Reddy, D.S.1    Rogawski, M.A.2
  • 81
    • 0033714804 scopus 로고    scopus 로고
    • Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself
    • Reddy D.S., Rogawski M.A. Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself. J. Pharmacol. Exp. Ther. 295:2000b;1241-1248.
    • (2000) J. Pharmacol. Exp. Ther. , vol.295 , pp. 1241-1248
    • Reddy, D.S.1    Rogawski, M.A.2
  • 82
    • 0026503730 scopus 로고
    • Catamenial epilepsy and gosorelin (letter)
    • Reid B.A., Gangar K.F. Catamenial epilepsy and gosorelin (letter). Lancet. 339:1992;253.
    • (1992) Lancet , vol.339 , pp. 253
    • Reid, B.A.1    Gangar, K.F.2
  • 83
    • 0029586822 scopus 로고
    • Corticosteroids enhance convulsion susceptibility via central mineralocorticoid receptors
    • Roberts A.J., Keith L.D. Corticosteroids enhance convulsion susceptibility via central mineralocorticoid receptors. Psychoneuroendocrinology. 20:1995;891-902.
    • (1995) Psychoneuroendocrinology , vol.20 , pp. 891-902
    • Roberts, A.J.1    Keith, L.D.2
  • 84
    • 0033198566 scopus 로고    scopus 로고
    • Neuroactive steroids: Mechanism of action and neuropsychopharmacological perspectives
    • Rupprecht R., Holsboer F. Neuroactive steroids: mechanism of action and neuropsychopharmacological perspectives. Trends Neurosci. 22:1999a;410-416.
    • (1999) Trends Neurosci. , vol.22 , pp. 410-416
    • Rupprecht, R.1    Holsboer, F.2
  • 85
    • 0032922384 scopus 로고    scopus 로고
    • Neuropsychopharmacological properties of neuroactive steroids
    • Rupprecht R., Holsboer F. Neuropsychopharmacological properties of neuroactive steroids. Steroids. 64:1999b;83-91.
    • (1999) Steroids , vol.64 , pp. 83-91
    • Rupprecht, R.1    Holsboer, F.2
  • 87
    • 0031432952 scopus 로고    scopus 로고
    • Neurosteroids in the hippocampus: Neuronal plasticity and memory
    • Schumacher M., Guennoun R., Robel P., Baulieu E.E. Neurosteroids in the hippocampus: Neuronal plasticity and memory. Stress. 21:1997;65-78.
    • (1997) Stress , vol.21 , pp. 65-78
    • Schumacher, M.1    Guennoun, R.2    Robel, P.3    Baulieu, E.E.4
  • 88
    • 0032884132 scopus 로고    scopus 로고
    • Genomic and membrane actions of progesterone: Implications for reproductive physiology and behaviour
    • Schumacher M., Coirini H., Robert F., Guennoun R., El-Etr M. Genomic and membrane actions of progesterone: implications for reproductive physiology and behaviour. Behav. Brain Res. 105:1999;37-52.
    • (1999) Behav. Brain Res. , vol.105 , pp. 37-52
    • Schumacher, M.1    Coirini, H.2    Robert, F.3    Guennoun, R.4    El-Etr, M.5
  • 89
    • 0024520324 scopus 로고
    • Steroid hormone effects on picrotoxin-induced seizures in female and male rats
    • Schwartz-Giblin S., Korotzer A., Pfaff D.W. Steroid hormone effects on picrotoxin-induced seizures in female and male rats. Brain Res. 476:1989;240-247.
    • (1989) Brain Res. , vol.476 , pp. 240-247
    • Schwartz-Giblin, S.1    Korotzer, A.2    Pfaff, D.W.3
  • 90
    • 0001345641 scopus 로고    scopus 로고
    • Limbic anatomy and physiology
    • J. Jr. Engel, & T.A. Pedley. Philadelphia: Lippincott Raven
    • Schwartzkroin P.A., McIntyre D.C. Limbic anatomy and physiology. Engel J. Jr, Pedley T.A. Epilepsy: A Comprehensive Textbook. 1997;323-340 Lippincott Raven, Philadelphia.
    • (1997) Epilepsy: A Comprehensive Textbook , pp. 323-340
    • Schwartzkroin, P.A.1    McIntyre, D.C.2
  • 91
    • 0344364894 scopus 로고
    • The anesthetic effect of steroid hormones
    • Selye H. The anesthetic effect of steroid hormones. Proc. Soc. Exp. Biol. Med. 46:1941;116-121.
    • (1941) Proc. Soc. Exp. Biol. Med. , vol.46 , pp. 116-121
    • Selye, H.1
  • 93
    • 0033970185 scopus 로고    scopus 로고
    • Estrogen is more than just a 'sex hormone': Novel sites for estrogen action in the hippocampus and cerebral cortex
    • Shughrue P.J., Merchenthaler I. Estrogen is more than just a 'sex hormone': Novel sites for estrogen action in the hippocampus and cerebral cortex. Front. Neuroendocrinol. 21:2000;95-101.
    • (2000) Front. Neuroendocrinol. , vol.21 , pp. 95-101
    • Shughrue, P.J.1    Merchenthaler, I.2
  • 94
    • 0031683068 scopus 로고    scopus 로고
    • GABA(A) receptor function in epileptic human dentate granule cells: Comparison to epileptic and control rat
    • Shumate M.D., Lin D.D., Gibbs J.W. III, Holloway K.L., Coulter D.A. GABA(A) receptor function in epileptic human dentate granule cells: comparison to epileptic and control rat. Epilepsy Res. 32:1998;114-128.
    • (1998) Epilepsy Res. , vol.32 , pp. 114-128
    • Shumate, M.D.1    Lin, D.D.2    Gibbs J.W. III3    Holloway, K.L.4    Coulter, D.A.5
  • 95
    • 0024343839 scopus 로고
    • Estradiol administration increases neuronal responses to excitatory amino acids as a long term effect
    • Smith S.S. Estradiol administration increases neuronal responses to excitatory amino acids as a long term effect. Brain Res. 503:1989;354-357.
    • (1989) Brain Res. , vol.503 , pp. 354-357
    • Smith, S.S.1
  • 96
    • 0024215765 scopus 로고
    • Locally applied estrogens potentiate glutamate-evoked excitation of cerebellar Purkinje cells
    • Smith S.S., Waterhouse B.D., Woodward D.J. Locally applied estrogens potentiate glutamate-evoked excitation of cerebellar Purkinje cells. Brain Res. 475:1988;272-282.
    • (1988) Brain Res. , vol.475 , pp. 272-282
    • Smith, S.S.1    Waterhouse, B.D.2    Woodward, D.J.3
  • 99
    • 0014265499 scopus 로고
    • The effect of certain progestins and estrogens on the threshold of electrically induced seizure patterns
    • Stitt S.L., Kinnard W.J. The effect of certain progestins and estrogens on the threshold of electrically induced seizure patterns. Neurology. 18:1968;213-216.
    • (1968) Neurology , vol.18 , pp. 213-216
    • Stitt, S.L.1    Kinnard, W.J.2
  • 104
    • 0033622151 scopus 로고    scopus 로고
    • Expression of 5α-reductase and 3α-hydroxisteroid oxidoreductase in the hippocampus of patients with chronic temporal lobe epilepsy
    • Stoffel-Wagner B., Beyenburg S., Watzka M., Blümcke I., Bauer J., Schramm J., Bidlingmaier F., Elger C.E. Expression of 5α-reductase and 3α-hydroxisteroid oxidoreductase in the hippocampus of patients with chronic temporal lobe epilepsy. Epilepsia. 41:2000;140-147.
    • (2000) Epilepsia , vol.41 , pp. 140-147
    • Stoffel-Wagner, B.1    Beyenburg, S.2    Watzka, M.3    Blümcke, I.4    Bauer, J.5    Schramm, J.6    Bidlingmaier, F.7    Elger, C.E.8
  • 105
    • 0025806706 scopus 로고
    • Castration alters susceptibility of male rats to specific seizures
    • Thomas J., McLean J.H. Castration alters susceptibility of male rats to specific seizures. Physiol. Behav. 49:1991;1177-1179.
    • (1991) Physiol. Behav. , vol.49 , pp. 1177-1179
    • Thomas, J.1    McLean, J.H.2
  • 106
    • 0028824323 scopus 로고
    • Effects of age on messenger RNA expression of glucocorticoid, thyroid hormone, androgen, and estrogen receptors in postmortem human hippocampus
    • Tohgi H., Utsugisawa K., Yamagata M., Yoshimura M. Effects of age on messenger RNA expression of glucocorticoid, thyroid hormone, androgen, and estrogen receptors in postmortem human hippocampus. Brain Res. 700:1995;245-253.
    • (1995) Brain Res. , vol.700 , pp. 245-253
    • Tohgi, H.1    Utsugisawa, K.2    Yamagata, M.3    Yoshimura, M.4
  • 107
    • 0034029877 scopus 로고    scopus 로고
    • Novel brain function: Biosynthesis and action of neurosteroids in neurons
    • Tsutsui K., Ukena K., Usui M., Sakamoto H., Takase M. Novel brain function: biosynthesis and action of neurosteroids in neurons. Neurosci. Res. 36:2000;261-273.
    • (2000) Neurosci. Res. , vol.36 , pp. 261-273
    • Tsutsui, K.1    Ukena, K.2    Usui, M.3    Sakamoto, H.4    Takase, M.5
  • 113
    • 0033152160 scopus 로고    scopus 로고
    • Effects of estrogen in the CNS
    • Woolley C.S. Effects of estrogen in the CNS. Curr. Opin. Neurobiol. 9:1999;349-354.
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 349-354
    • Woolley, C.S.1
  • 114
    • 0034018497 scopus 로고    scopus 로고
    • Estradiol facilitates kainic acid-induced, but not flurothyl-induced, behavioral seizure activity in adult female rats
    • Woolley C.S. Estradiol facilitates kainic acid-induced, but not flurothyl-induced, behavioral seizure activity in adult female rats. Epilepsia. 41:2000;510-515.
    • (2000) Epilepsia , vol.41 , pp. 510-515
    • Woolley, C.S.1
  • 115
    • 0027445017 scopus 로고
    • Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat
    • Woolley C.S., McEwen B.S. Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat. J. Comp. Neurol. 336:1993;293-306.
    • (1993) J. Comp. Neurol. , vol.336 , pp. 293-306
    • Woolley, C.S.1    McEwen, B.S.2
  • 116
    • 0032253107 scopus 로고    scopus 로고
    • Hormonal effects on the brain
    • Woolley C.S., Schwartzkroin P.A. Hormonal effects on the brain. Epilepsia. 39:(8):1998;S2-S8.
    • (1998) Epilepsia , vol.39 , Issue.8 , pp. 2-S8
    • Woolley, C.S.1    Schwartzkroin, P.A.2
  • 117
    • 0029744424 scopus 로고    scopus 로고
    • Estradiol increases the frequency of multiple synapse boutons in the hippocampal CA1 region of the adult female rat
    • Woolley C.S., Wenzel H.J., Schwartzkroin P.A. Estradiol increases the frequency of multiple synapse boutons in the hippocampal CA1 region of the adult female rat. J. Comp. Neurol. 373:1996;108-117.
    • (1996) J. Comp. Neurol. , vol.373 , pp. 108-117
    • Woolley, C.S.1    Wenzel, H.J.2    Schwartzkroin, P.A.3
  • 118
    • 0033547019 scopus 로고    scopus 로고
    • Catamenial epilepsy: Clinical aspects
    • Zahn C. Catamenial epilepsy: clinical aspects. Neurology. 53:(1):1999;S34-S37.
    • (1999) Neurology , vol.53 , Issue.1 , pp. 34-S37
    • Zahn, C.1
  • 119
    • 0033377029 scopus 로고    scopus 로고
    • Neuroactive steroids: Their mechanism of action and their function in the stress response
    • Zinder O., Dar D.E. Neuroactive steroids: their mechanism of action and their function in the stress response. Acta Physiol. Scand. 167:1999;181-188.
    • (1999) Acta Physiol. Scand. , vol.167 , pp. 181-188
    • Zinder, O.1    Dar, D.E.2


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