Antiepileptic drug discovery and development: What have we learned and where are we going?

Pharmaceuticals

Volumn 3, Issue 9, 2010, Pages 2884-2899

  Gerlach, Aaron C ^a   Krajewski, Jeffrey L ^a  

^a Icagen Inc   (United States)

Author keywords

AED; Anticonvulsant; Antiepileptic; Epilepsy; Seizure

Indexed keywords

2 ISOPROPYLVALERAMIDE; 2,2,3,3 TETRAMETHYLCYCLOPROPANECARBONYLUREA; ANTICONVULSIVE AGENT; BRIVARACETAM; CARBAMAZEPINE; CENTRAL DEPRESSANT AGENT; CLONAZEPAM; D 21329; DEACETYLCOLCHICINE; DIAZEPAM; ESLICARBAZEPINE ACETATE; ETIRACETAM; FLUPIRTINE; GABAPENTIN; ICA 105665; ICA 27243; LICARBAZEPINE; N METHYL 2,2,3,3 TETRAMETHYLCYCLOPROPANECARBOXAMIDE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PLACEBO; POTASSIUM CHANNEL KCNQ2; POTASSIUM CHANNEL KCNQ3; PREGABALIN; RETIGABINE; UNCLASSIFIED DRUG; VALNOCTAMIDE; VALPROIC ACID; VALROCEMIDE; ZEBINIX;

ABSENCE OF SIDE EFFECTS; ANTICONVULSANT ACTIVITY; AUDIOGENIC SEIZURE; CLINICAL TRIAL; DIZZINESS; DOSAGE SCHEDULE COMPARISON; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG DOSE INCREASE; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG MARKETING; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SAFETY; DRUG TOLERABILITY; DRUG TRANSFORMATION; DRUG WITHDRAWAL; EPILEPSY; FATIGUE; FOCAL EPILEPSY; GRAND MAL SEIZURE; HUMAN; IN VIVO STUDY; NONHUMAN; PHARMACOPHORE; REVIEW; SEIZURE; SOMNOLENCE; TONIC CLONIC SEIZURE; UNSPECIFIED SIDE EFFECT;

EID: 77957258627     PISSN: None     EISSN: 14248247     Source Type: Journal    
DOI: 10.3390/ph3092884     Document Type: Review

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