Effects of neonatal MK-801 treatment on p70S6K-S6/eIF4B signal pathways and protein translation in the frontal cortex of the developing rat brain

International Journal of Neuropsychopharmacology

Volumn 13, Issue 9, 2010, Pages 1233-1246

  Kim, Se Hyun ^a,b   Park, Hong Geun ^a,b   Kim, Han Soo ^b   Ahn, Yong Min ^a   Kim, Yong Sik ^a  

^a Seoul National University   (South Korea)

^b Seoul National University Hospital   (South Korea)

Author keywords

N methyl d aspartate receptor; Neurodevelopment; protein synthesis; schizophrenia; small ribosomal protein 6

Indexed keywords

DIZOCILPINE; INITIATION FACTOR 4B; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; P70 RIBOSOMA S6 KINASE; PROTEIN KINASE B; S6 KINASE; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CINGULATE GYRUS; CONTROLLED STUDY; DRUG EFFECT; FEMALE; FRONTAL CORTEX; INSULA; NEWBORN; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; TRANSLATION INITIATION;

ANIMALS; ANIMALS, NEWBORN; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EUKARYOTIC INITIATION FACTORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FRONTAL LOBE; NEUROPROTECTIVE AGENTS; PHOSPHORYLATION; PREFRONTAL CORTEX; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 77957238178     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145709991192     Document Type: Article

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