Inhibition of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase by flavonoids: A quantitative structure-activity relationship study

IUBMB Life

Volumn 60, Issue 12, 2008, Pages 853-858

  Ogunbayo, Oluseye A ^a   Harris, Robert M ^a   Waring, Rosemary H ^a   Kirk, Christopher J ^a   Michelangeli, Francesco ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Ca2+ ATPase; Flavonoid; Phytoestrogen; QSAR; Quercetin; SERCA

Indexed keywords

3 HYDROXYFLAVONE; 3',4', DIHYDROXYFLAVONE; 3',4',7,8 TETRAHYDROXYFLAVONE; 3,6 DIHYDROXYFLAVONE; 3,7 DIHYDROXYFLAVONE; 6 HYDROXYFLAVONE; 7 HYDROXYFLAVONE; 7,8 DIHYDROXYFLAVONE; APIGENIN; BAICALEIN; CHRYSIN; DAIDZEIN; FISETIN; FLAVONE; FLAVONE DERIVATIVE; FLAVONOID; GALANGIN; GENISTEIN; HESPERETIN; KAEMPFEROL; LUTEOLIN; MORIN; MYRICETIN; NARINGENIN; PRIMULETIN; QUERCETIN; RUTOSIDE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 1A; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE 2B; UNCLASSIFIED DRUG; CALCIUM; ENZYME INHIBITOR; THAPSIGARGIN;

ARTICLE; CHEMICAL STRUCTURE; HYDROXYLATION; IC 50; STRUCTURE ACTIVITY RELATION; ANIMAL; BRAIN; CALCIUM SIGNALING; CYTOPLASM; DRUG ANTAGONISM; DRUG EFFECT; ENDOPLASMIC RETICULUM; ENZYMOLOGY; METABOLISM; MICROSOME; MITOCHONDRION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RABBIT; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; SWINE;

ANIMALS; BRAIN; CALCIUM; CALCIUM SIGNALING; CYTOPLASM; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; FLAVONOIDS; MICROSOMES; MITOCHONDRIA; MUSCLE, SKELETAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RABBITS; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SWINE; THAPSIGARGIN;

EID: 59649083745     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.132     Document Type: Article

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