메뉴 건너뛰기




Volumn 32, Issue 3, 2010, Pages 239-246

Protective effect of Neorhodomela aculeata methanolic extract through the suppressive action on NF-κB and STAT pathway in IL-1β and IFN-γ induced β-cell damage

Author keywords

diabetics; Neorhodomela aculeata; NF kappa B; nitric oxide; STAT 1; cell

Indexed keywords

ACULEATA; NEORHODOMELA; RATTUS;

EID: 77957065817     PISSN: 19769571     EISSN: 20929293     Source Type: Journal    
DOI: 10.1007/s13258-010-0003-z     Document Type: Article
Times cited : (3)

References (44)
  • 1
    • 0037204953 scopus 로고    scopus 로고
    • A road map for those who don't know JAK-STAT
    • DOI 10.1126/science.1071545
    • D.S. Aaronson C.M. Horvath 2002 A road map for those who don't know JAK-STAT Science 296 5573 1653 1655 10.1126/science.1071545 12040185 1:CAS:528:DC%2BD38XktlChu7o%3D (Pubitemid 34579157)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1653-1655
    • Aaronson, D.S.1    Horvath, C.M.2
  • 2
    • 0030271387 scopus 로고    scopus 로고
    • Nf-κB: Ten years after
    • DOI 10.1016/S0092-8674(00)81318-5
    • P.A. Baeuerle D. Baltimore 1996 NF-kappa B: ten years after Cell 87 1 13 20 10.1016/S0092-8674(00)81318-5 8858144 1:CAS:528:DyaK28XmtFeit7g%3D (Pubitemid 26337386)
    • (1996) Cell , vol.87 , Issue.1 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 3
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • 8011280 1:CAS:528:DyaK2cXivFKjurY%3D
    • P.A. Baeuerle T. Henkel 1994 Function and activation of NF-kappa B in the immune system Annu. Rev. Immunol. 12 141 179 8011280 1:CAS:528: DyaK2cXivFKjurY%3D
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 4
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • DOI 10.1146/annurev.immunol.14.1.649
    • A.S. Baldwin Jr 1996 The NF-kappa B and I kappa B proteins: new discoveries and insights Annu. Rev. Immunol. 14 649 683 10.1146/annurev.immunol. 14.1.649 8717528 1:CAS:528:DyaK28XitlCgtbc%3D (Pubitemid 26130197)
    • (1996) Annual Review of Immunology , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 5
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • 10.1016/0003-2697(76)90527-3 942051 1:CAS:528:DyaE28XksVehtrY%3D
    • M.M. Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem 72 248 254 10.1016/0003-2697(76)90527-3 942051 1:CAS:528:DyaE28XksVehtrY%3D
    • (1976) Anal. Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 6
    • 0027934873 scopus 로고
    • TNF-α and IFN-γ potentiate the deleterious effects of IL-1β on mouse pancreatic islets mainly via generation of nitric oxide
    • DOI 10.1016/1043-4666(94)90064-7
    • M. Cetkovic-Cvrlje D.L. Eizirik 1994 TNF-alpha and IFN-gamma potentiate the deleterious effects of IL-1 beta on mouse pancreatic islets mainly via generation of nitric oxide Cytokine 6 4 399 406 10.1016/1043-4666(94)90064-7 7948748 1:CAS:528:DyaK2cXlsFClu78%3D (Pubitemid 24263885)
    • (1994) Cytokine , vol.6 , Issue.4 , pp. 399-406
    • Cetkovic-Cvrlje, M.1    Eizirik, D.L.2
  • 7
    • 0028900805 scopus 로고
    • Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase
    • 10.1084/jem.181.2.559 7530759 1:CAS:528:DyaK2MXjtFyhu7g%3D
    • J.A. Corbett M.L. McDaniel 1995 Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase J. Exp. Med. 181 2 559 568 10.1084/jem.181.2.559 7530759 1:CAS:528:DyaK2MXjtFyhu7g%3D
    • (1995) J. Exp. Med. , vol.181 , Issue.2 , pp. 559-568
    • Corbett, J.A.1    McDaniel, M.L.2
  • 8
    • 0035854646 scopus 로고    scopus 로고
    • SOCS-1 Protein Prevents Janus Kinase/STAT-dependent Inhibition of β Cell Insulin Gene Transcription and Secretion in Response to Interferon-γ
    • DOI 10.1074/jbc.M103235200
    • S. Cottet P. Dupraz F. Hamburger W. Dolci M. Jaquet B. Thorens 2001 SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma J. Biol. Chem. 276 28 25862 25870 10.1074/jbc.M103235200 11342558 1:CAS:528:DC%2BD3MXlsVKgtbY%3D (Pubitemid 37412789)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.28 , pp. 25862-25870
    • Cottet, S.1    Dupraz, P.2    Hamburger, F.3    Dolci, W.4    Jaquet, M.5    Thorens, B.6
  • 9
    • 0031827241 scopus 로고    scopus 로고
    • Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells
    • DOI 10.1007/s001250051036
    • M.I. Darville D.L. Eizirik 1998 Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells Diabetologia 41 9 1101 1108 10.1007/s001250051036 9754830 1:CAS:528:DyaK1cXls12hsr4%3D (Pubitemid 28394417)
    • (1998) Diabetologia , vol.41 , Issue.9 , pp. 1101-1108
    • Darville, M.I.1    Eizirik, D.L.2
  • 10
    • 73949126369 scopus 로고    scopus 로고
    • Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes
    • 1:CAS:528:DC%2BC3cXht1aisrc%3D
    • M.Y. Donath M. Boni-Schnetzler H. Ellingsgaard J.A. Ehses 2009 Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes Physiology (Bethesda) 24 325 331 1:CAS:528:DC%2BC3cXht1aisrc%3D
    • (2009) Physiology (Bethesda) , vol.24 , pp. 325-331
    • Donath, M.Y.1    Boni-Schnetzler, M.2    Ellingsgaard, H.3    Ehses, J.A.4
  • 11
    • 31844445207 scopus 로고    scopus 로고
    • Evaluation of antioxidant property of extract and fractions obtained from a red alga, Polysiphonia urceolata
    • DOI 10.1016/j.foodchem.2004.12.015, PII S0308814605000282
    • X.J. Duan W.W. Zhang X.M. Li B.E. Wang 2006 Evaluation of antioxidant property of extrct and fractions obtained from a red alga, Polysiphonia urceolata Food Chemistry 95 37 43 10.1016/j.foodchem.2004.12.015 1:CAS:528:DC%2BD2MXpsF2gs7k%3D (Pubitemid 43181188)
    • (2006) Food Chemistry , vol.95 , Issue.1 , pp. 37-43
    • Duan, X.-J.1    Zhang, W.-W.2    Li, X.-M.3    Wang, B.-G.4
  • 12
    • 0030005411 scopus 로고    scopus 로고
    • The harmony of the spheres: Inducible nitric oxide synthase and related genes in pancreatic beta cells
    • 10.1007/BF00403906 8858209 1:CAS:528:DyaK28XlsFOmsbg%3D
    • D.L. Eizirik M. Flodstrom A.E. Karlsen N. Welsh 1996 The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells Diabetologia 39 8 875 890 10.1007/BF00403906 8858209 1:CAS:528: DyaK28XlsFOmsbg%3D
    • (1996) Diabetologia , vol.39 , Issue.8 , pp. 875-890
    • Eizirik, D.L.1    Flodstrom, M.2    Karlsen, A.E.3    Welsh, N.4
  • 13
    • 33645518035 scopus 로고    scopus 로고
    • Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents
    • 10.1073/pnas.0508166103 16551748 1:CAS:528:DC%2BD28XjsVGlsbk%3D
    • R. Eldor A. Yeffet K. Baum V. Doviner D. Amar Y. Ben-Neriah G. Christofori A. Peled J.C. Carel 2006 Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents Proc. Natl. Acad. Sci. U.S.A. 103 13 5072 5077 10.1073/pnas.0508166103 16551748 1:CAS:528: DC%2BD28XjsVGlsbk%3D
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , Issue.13 , pp. 5072-5077
    • Eldor, R.1    Yeffet, A.2    Baum, K.3    Doviner, V.4    Amar, D.5    Ben-Neriah, Y.6    Christofori, G.7    Peled, A.8    Carel, J.C.9
  • 14
    • 0242268904 scopus 로고    scopus 로고
    • Target Cell Expression of Suppressor of Cytokine Signaling-1 Prevents Diabetes in the NOD Mouse
    • DOI 10.2337/diabetes.52.11.2696
    • M. Flodstrom-Tullberg D. Yadav R. Hagerkvist D. Tsai P. Secrest A. Stotland N. Sarvetnick 2003 Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse Diabetes 52 11 2696 2700 10.2337/diabetes.52.11.2696 14578288 (Pubitemid 37339699)
    • (2003) Diabetes , vol.52 , Issue.11 , pp. 2696-2700
    • Flodstrom-Tullberg, M.1    Yadav, D.2    Hagerkvist, R.3    Tsai, D.4    Secrest, P.5    Stotland, A.6    Sarvetnick, N.7
  • 15
    • 0020448709 scopus 로고
    • 15N]nitrate in biological fluids
    • DOI 10.1016/0003-2697(82)90118-X
    • L.C. Green D.A. Wagner J. Glogowski P.L. Skipper J.S. Wishnok S.R. Tannenbaum 1982 Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids Anal. Biochem. 126 1 131 138 10.1016/0003-2697(82)90118-X 7181105 1:CAS:528:DyaL38XlvFGgtLY%3D (Pubitemid 13203451)
    • (1982) Analytical Biochemistry , vol.126 , Issue.1 , pp. 131-138
    • Green, L.C.1    Wagner, D.A.2    Glogowski, J.3
  • 16
    • 0030997703 scopus 로고    scopus 로고
    • Interferon-γ increases the sensitivity of islets of langerhans for inducible nitric-oxide synthase expression induced by interleukin 1
    • DOI 10.1074/jbc.272.21.13697
    • M.R. Heitmeier A.L. Scarim J.A. Corbett 1997 Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1 J Biol Chem. 272 21 13697 13704 10.1074/jbc.272.21.13697 9153221 1:CAS:528:DyaK2sXjsFWhsb8%3D (Pubitemid 27224804)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.21 , pp. 13697-13704
    • Heitmeier, M.R.1    Scarim, A.L.2    Corbett, J.A.3
  • 17
    • 0032832969 scopus 로고    scopus 로고
    • Prolonged STAT1 activation is associated with interferon-γ priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans
    • DOI 10.1074/jbc.274.41.29266
    • M.R. Heitmeier A.L. Scarim J.A. Corbett 1999 Prolonged STAT1 activation is associated with interferon-gamma priming for interleukin-1-induced inducible nitric-oxide synthase expression by islets of Langerhans J. Biol. Chem. 274 41 29266 29273 10.1074/jbc.274.41.29266 10506184 1:CAS:528:DyaK1MXmslWqtbw%3D (Pubitemid 29477093)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.41 , pp. 29266-29273
    • Heitmeier, M.R.1    Scarim, A.L.2    Corbett, J.A.3
  • 19
    • 0034832208 scopus 로고    scopus 로고
    • Biological and clinical significance of the JAK-STAT pathway; Lessons from knockout mice
    • 10.1007/PL00000267 11603847 1:CAS:528:DC%2BD3MXotFOrs70%3D
    • P. Igaz S. Toth A. Falus 2001 Biological and clinical significance of the JAK-STAT pathway; lessons from knockout mice Inflamm. Res. 50 9 435 441 10.1007/PL00000267 11603847 1:CAS:528:DC%2BD3MXotFOrs70%3D
    • (2001) Inflamm. Res. , vol.50 , Issue.9 , pp. 435-441
    • Igaz, P.1    Toth, S.2    Falus, A.3
  • 20
    • 0037116417 scopus 로고    scopus 로고
    • 15 acetogenins from the red alga Laurencia obtusa
    • DOI 10.1016/S0031-9422(01)00407-1, PII S0031942201004071
    • D. Iliopoulou C. Vagias C. Harvala V. Roussis 2002 C(15) Acetogenins from the red alga Laurencia obtusa Phytochemistry 59 1 111 116 10.1016/S0031- 9422(01)00407-1 11754953 1:CAS:528:DC%2BD3MXpt1aitbY%3D (Pubitemid 34073349)
    • (2002) Phytochemistry , vol.59 , Issue.1 , pp. 111-116
    • Iliopoulou, D.1    Vagias, C.2    Harvala, C.3    Roussis, V.4
  • 21
    • 33846980122 scopus 로고    scopus 로고
    • Inhibition of cytokine-mediated nitric oxide synthase expression in rat insulinoma cells by scoparone
    • 10.1248/bpb.30.242 17268059 1:CAS:528:DC%2BD2sXkvVSnu7g%3D
    • E.K. Kim K.B. Kwon J.H. Lee B.H. Park J.W. Park H.K. Lee E.C. Jhee J.Y. Yang 2007 Inhibition of cytokine-mediated nitric oxide synthase expression in rat insulinoma cells by scoparone Biol Pharm. Bull. 30 2 242 246 10.1248/bpb.30.242 17268059 1:CAS:528:DC%2BD2sXkvVSnu7g%3D
    • (2007) Biol Pharm. Bull. , vol.30 , Issue.2 , pp. 242-246
    • Kim, E.K.1    Kwon, K.B.2    Lee, J.H.3    Park, B.H.4    Park, J.W.5    Lee, H.K.6    Jhee, E.C.7    Yang, J.Y.8
  • 22
    • 37349025744 scopus 로고    scopus 로고
    • Flavonoids protect against cytokine-induced pancreatic β-cell damage through suppression of nuclear factor κB activation
    • DOI 10.1097/mpa.0b013e31811ed0d2, PII 0000667620071100000191
    • E.K. Kim K.B. Kwon M.Y. Song M.J. Han J.H. Lee Y.R. Lee D.G. Ryu B.H. Park J.W. Park 2007 Flavonoids protect against cytokine-induced pancreatic beta-cell damage through suppression of nuclear factor kappaB activation Pancreas 35 4 e1 9 10.1097/mpa.0b013e31811ed0d2 18090225 (Pubitemid 350307390)
    • (2007) Pancreas , vol.35 , Issue.4
    • Kim, E.-K.1    Kwon, K.-B.2    Song, M.-Y.3    Han, M.-J.4    Lee, J.-H.5    Lee, Y.-R.6    Lee, J.-H.7    Ryu, D.-G.8    Park, B.-H.9    Park, J.-W.10
  • 23
    • 0033034494 scopus 로고    scopus 로고
    • Two new bromophenols from the red alga Odonthalia corymbifera
    • DOI 10.1021/np980324p
    • H. Kurihara T. Mitani J. Kawabata K. Takahashi 1999 Two new bromophenols from the red alga Odonthalia corymbifera J. Nat. Prod 62 6 882 884 10.1021/np980324p 10395508 1:CAS:528:DyaK1MXislyjtbw%3D (Pubitemid 29296328)
    • (1999) Journal of Natural Products , vol.62 , Issue.6 , pp. 882-884
    • Kurihara, H.1    Mitani, T.2    Kawabata, J.3    Takahashi, K.4
  • 24
    • 33746911644 scopus 로고    scopus 로고
    • Cortex cinnamomi extract prevents streptozotocin- and cytokine-induced beta-cell damage by inhibiting NF-kappaB
    • 16865774
    • K.B. Kwon E.K. Kim E.S. Jeong Y.H. Lee Y.R. Lee J.W. Park D.G. Ryu B.H. Park 2006 Cortex cinnamomi extract prevents streptozotocin- and cytokine-induced beta-cell damage by inhibiting NF-kappaB World J. Gastroenterol. 12 27 4331 4337 16865774
    • (2006) World J. Gastroenterol. , vol.12 , Issue.27 , pp. 4331-4337
    • Kwon, K.B.1    Kim, E.K.2    Jeong, E.S.3    Lee, Y.H.4    Lee, Y.R.5    Park, J.W.6    Ryu, D.G.7    Park, B.H.8
  • 25
    • 33744934349 scopus 로고
    • A survey of medicinal seaweed resources in Liaodong Peninsula
    • X. Li O.S. Kwak H. Jin 1994 A survey of medicinal seaweed resources in Liaodong Peninsula Chinese Marine Pharmaceut. Sci. 51 50 54
    • (1994) Chinese Marine Pharmaceut. Sci. , vol.51 , pp. 50-54
    • Li, X.1    Kwak, O.S.2    Jin, H.3
  • 26
    • 33744934471 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory activities of the methanolic extract of Neorhodomela aculeate in hippocampal and microglial cells
    • DOI 10.1248/bpb.29.1212
    • C.S. Lim D.Q. Jin J.Y. Sung J.H. Lee H.G. Choi I. Ha J.S. Han 2006 Antioxidant and anti-inflammatory activities of the methanolic extract of Neorhodomela aculeata in Hippocampal and Microglial Cells Biol. Pharm. Bull. 29 6 1212 1216 10.1248/bpb.29.1212 16755019 1:CAS:528:DC%2BD28XnslOmurg%3D (Pubitemid 43845485)
    • (2006) Biological and Pharmaceutical Bulletin , vol.29 , Issue.6 , pp. 1212-1216
    • Lim, C.S.1    Jin, D.-Q.2    Sung, J.-Y.3    Lee, J.H.4    Choi, H.G.5    Ha, I.6    Han, J.-S.7
  • 27
    • 0035983492 scopus 로고    scopus 로고
    • NFκB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes
    • DOI 10.1677/joe.0.1730457
    • J.G. Mabley G. Hasko L. Liaudet F. Soriano G.J. Southan A.L. Salzman C. Szabo 2002 NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes J. Endocrinol. 173 3 457 464 10.1677/joe.0.1730457 12065235 1:CAS:528:DC%2BD38Xlt1ehtbw%3D (Pubitemid 34704717)
    • (2002) Journal of Endocrinology , vol.173 , Issue.3 , pp. 457-464
    • Mabley, J.G.1    Hasko, G.2    Liaudet, L.3    Soriano, F.4    Southan, G.J.5    Salzman, A.L.6    Szabo, C.7
  • 28
    • 0029817047 scopus 로고    scopus 로고
    • The role of interleukin-1 in the pathogenesis of IDDM
    • 10.1007/BF00400649 8877284 1:CAS:528:DyaK28XlslOgsL0%3D
    • T. Mandrup-Poulsen 1996 The role of interleukin-1 in the pathogenesis of IDDM Diabetologia 39 9 1005 1029 10.1007/BF00400649 8877284 1:CAS:528: DyaK28XlslOgsL0%3D
    • (1996) Diabetologia , vol.39 , Issue.9 , pp. 1005-1029
    • Mandrup-Poulsen, T.1
  • 29
    • 11144237925 scopus 로고    scopus 로고
    • 2-terminal kinase and Janus kinase/signal transducer and activator of transcription pathways
    • DOI 10.1210/en.2004-0850
    • T. Matsuda K. Ferreri I. Todorov Y. Kuroda C.V. Smith F. Kandeel Y. Mullen 2005 Silymarin protects pancreatic beta-cells against cytokine-mediated toxicity: implication of c-Jun NH2-terminal kinase and janus kinase/signal transducer and activator of transcription pathways Endocrinology 146 1 175 185 10.1210/en.2004-0850 15459112 1:CAS:528:DC%2BD2cXhtFGmt7nI (Pubitemid 40051737)
    • (2005) Endocrinology , vol.146 , Issue.1 , pp. 175-185
    • Matsuda, T.1    Ferreri, K.2    Todorov, I.3    Kuroda, Y.4    Smith, C.V.5    Kandeel, F.6    Mullen, Y.7
  • 30
    • 0031906550 scopus 로고    scopus 로고
    • Signal transduction through NF-κB
    • DOI 10.1016/S0167-5699(97)01197-3, PII S0167569997011973
    • M.J. May S. Ghosh 1998 Signal transduction through NF-kappa B Immunol. Today 19 2 80 88 10.1016/S0167-5699(97)01197-3 9509763 1:CAS:528: DyaK1cXhtlWlsLc%3D (Pubitemid 28097654)
    • (1998) Immunology Today , vol.19 , Issue.2 , pp. 80-88
    • May, M.J.1    Ghosh, S.2
  • 31
    • 0026497021 scopus 로고
    • Autoimmune tolerance and type 1 (insulin-dependent) diabetes mellitus
    • 10.1007/BF00586279 1478378
    • G.J. Nossal K.C. Herold C.C. Goodnow 1992 Autoimmune tolerance and type 1 (insulin-dependent) diabetes mellitus Diabetologia 35 Suppl2 S49 59 10.1007/BF00586279 1478378
    • (1992) Diabetologia , vol.35 , Issue.SUPPL. 2 , pp. 49-59
    • Nossal, G.J.1    Herold, K.C.2    Goodnow, C.C.3
  • 32
    • 0035973165 scopus 로고    scopus 로고
    • The protective effect of Amomum xanthoides extract against alloxan-induced diabetes through the suppression of NFkappaB activation
    • 11460883 1:CAS:528:DC%2BD3MXit1WhtA%3D%3D
    • B.H. Park J.W. Park 2001 The protective effect of Amomum xanthoides extract against alloxan-induced diabetes through the suppression of NFkappaB activation Exp. Mol. Med. 33 2 64 68 11460883 1:CAS:528:DC%2BD3MXit1WhtA%3D%3D
    • (2001) Exp. Mol. Med. , vol.33 , Issue.2 , pp. 64-68
    • Park, B.H.1    Park, J.W.2
  • 33
    • 0029009667 scopus 로고
    • Protective mechanism of glucose against alloxan-induced pancreatic beta-cell damage
    • 10.1006/bbrc.1995.1619 7741727 1:CAS:528:DyaK2MXlsF2msL0%3D
    • B.H. Park H.W. Rho J.W. Park C.G. Cho J.S. Kim H.T. Chung H.R. Kim 1995 Protective mechanism of glucose against alloxan-induced pancreatic beta-cell damage Biochem. Biophys. Res. Commun. 210 1 1 6 10.1006/bbrc.1995.1619 7741727 1:CAS:528:DyaK2MXlsF2msL0%3D
    • (1995) Biochem. Biophys. Res. Commun. , vol.210 , Issue.1 , pp. 1-6
    • Park, B.H.1    Rho, H.W.2    Park, J.W.3    Cho, C.G.4    Kim, J.S.5    Chung, H.T.6    Kim, H.R.7
  • 34
    • 33845190686 scopus 로고    scopus 로고
    • Anti-inflammatory effects of short chain fatty acids in IFN-γ-stimulated RAW 264.7 murine macrophage cells: Involvement of NF-κB and ERK signaling pathways
    • DOI 10.1016/j.intimp.2006.08.015, PII S156757690600261X
    • J.S. Park E.J. Lee J.C. Lee W.K. Kim H.S. Kim 2007 Anti-inflammatory effects of short chain fatty acids in IFN-gamma-stimulated RAW 264.7 murine macrophage cells: involvement of NF-kappaB and ERK signaling pathways Int. Immunopharmacol. 7 1 70 77 10.1016/j.intimp.2006.08.015 17161819 1:CAS:528:DC%2BD28Xht12ksbbF (Pubitemid 44856390)
    • (2007) International Immunopharmacology , vol.7 , Issue.1 , pp. 70-77
    • Park, J.-S.1    Lee, E.-J.2    Lee, J.-C.3    Kim, W.-K.4    Kim, H.-S.5
  • 35
    • 0019479052 scopus 로고
    • 2+-DNA complex
    • DOI 10.1016/0006-2952(81)90214-8
    • D.R. Phillips G.A. Carlyle 1981 The effect of physiological levels of divalent metal ions on the interaction of daunomycin with DNA: evidence of a ternary daunomycin-Cu2+-DNA complex Biochem. Pharmacol. 30 14 2021 2024 10.1016/0006-2952(81)90214-8 7271891 1:CAS:528:DyaL3MXmtFCkt7s%3D (Pubitemid 11071514)
    • (1981) Biochemical Pharmacology , vol.30 , Issue.14 , pp. 2021-2024
    • Phillips, D.R.1    Carlyle, G.A.2
  • 36
    • 0036476551 scopus 로고    scopus 로고
    • Stat1-dependent and -independent pathways in IFN-γ-dependent signaling
    • DOI 10.1016/S1471-4906(01)02118-4, PII S1471490601021184
    • C.V. Ramana M.P. Gil R.D. Schreiber G.R. Stark 2002 Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling Trends Immunol. 23 2 96 101 10.1016/S1471-4906(01)02118-4 11929133 1:CAS:528:DC%2BD38XivVSlsrg%3D (Pubitemid 34310151)
    • (2002) Trends in Immunology , vol.23 , Issue.2 , pp. 96-101
    • Ramana, C.V.1    Gil, M.P.2    Schreiber, R.D.3    Stark, G.R.4
  • 37
    • 67649449966 scopus 로고    scopus 로고
    • Fructus xanthii extract protects against cytokine-induced damage in pancreatic beta-cells through suppression of NF-kappaB activation
    • 19288032
    • M.Y. Song E.K. Kim H.J. Lee J.W. Park D.G. Ryu K.B. Kwon B.H. Park 2009 Fructus xanthii extract protects against cytokine-induced damage in pancreatic beta-cells through suppression of NF-kappaB activation Int. J. Mol. Med. 23 4 547 553 19288032
    • (2009) Int. J. Mol. Med. , vol.23 , Issue.4 , pp. 547-553
    • Song, M.Y.1    Kim, E.K.2    Lee, H.J.3    Park, J.W.4    Ryu, D.G.5    Kwon, K.B.6    Park, B.H.7
  • 38
    • 38449112228 scopus 로고    scopus 로고
    • Radix asari extract protects pancreatic beta cells against cytokine-induced toxicity:implication of the NF-kappaB-iNOS signaling cascade
    • 17912472
    • M.Y. Song K.A. Kim S.Y. Lee E.K. Kim N. Lv J.H. Lee J.W. Park D.G. Ryu K.B. Kwon B.H. Park 2007 Radix asari extract protects pancreatic beta cells against cytokine-induced toxicity:implication of the NF-kappaB-iNOS signaling cascade Int. J. Mol. Med. 20 5 769 775 17912472
    • (2007) Int. J. Mol. Med. , vol.20 , Issue.5 , pp. 769-775
    • Song, M.Y.1    Kim, K.A.2    Lee, S.Y.3    Kim, E.K.4    Lv, N.5    Lee, J.H.6    Park, J.W.7    Ryu, D.G.8    Kwon, K.B.9    Park, B.H.10
  • 40
    • 0025685395 scopus 로고
    • Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism
    • 10.1016/0014-5793(90)80502-A 2265709 1:CAS:528:DyaK3MXktVOqtw%3D%3D
    • C. Southern D. Schulster I.C. Green 1990 Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism FEBS Lett. 276 1-2 42 44 10.1016/0014-5793(90)80502-A 2265709 1:CAS:528:DyaK3MXktVOqtw%3D%3D
    • (1990) FEBS Lett. , vol.276 , Issue.12 , pp. 42-44
    • Southern, C.1    Schulster, D.2    Green, I.C.3
  • 41
    • 0028986193 scopus 로고
    • NF-kappa B: A lesson in family values
    • 10.1016/0092-8674(95)90506-5 7867060 1:CAS:528:DyaK2MXktV2isbg%3D
    • D. Thanos T. Maniatis 1995 NF-kappa B: a lesson in family values Cell 80 4 529 532 10.1016/0092-8674(95)90506-5 7867060 1:CAS:528:DyaK2MXktV2isbg%3D
    • (1995) Cell , vol.80 , Issue.4 , pp. 529-532
    • Thanos, D.1    Maniatis, T.2
  • 42
    • 0037380094 scopus 로고    scopus 로고
    • Antibacterial bromophenols from the marine red alga Rhodomela confervoides
    • DOI 10.1016/S0031-9422(03)00004-9
    • N. Xu X. Fan X. Yan X. Li R. Niu C.K. Tseng 2003 Antibacterial bromophenols from the marine red alga Rhodomela confervoides Phytochemistry 62 8 1221 1224 10.1016/S0031-9422(03)00004-9 12648540 1:CAS:528:DC%2BD3sXitFaitb4%3D (Pubitemid 36383590)
    • (2003) Phytochemistry , vol.62 , Issue.8 , pp. 1221-1224
    • Xu, N.1    Fan, X.2    Yan, X.3    Li, X.4    Niu, R.5    Tseng, C.K.6
  • 43
  • 44
    • 3042582969 scopus 로고    scopus 로고
    • Bromophenol derivatives from the red alga Rhodomela confervoides
    • DOI 10.1021/np030546+
    • J. Zhao X. Fan S. Wang S. Li S. Shang Y. Yang N. Xu Y. Lu J. Shi 2004 Bromophenol derivatives from the red alga Rhodomela confervoides J. Nat. Prod. 67 6 1032 1035 10.1021/np030546+ 15217289 1:CAS:528:DC%2BD2cXltFSqt7s%3D (Pubitemid 38823340)
    • (2004) Journal of Natural Products , vol.67 , Issue.6 , pp. 1032-1035
    • Zhao, J.1    Fan, X.2    Wang, S.3    Li, S.4    Shang, S.5    Yang, Y.6    Xu, N.7    Lu, Y.8    Shi, J.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.