Cultured cerebellar granule neurons as an in vitro aging model: Topoisomerase IIβ as an additional biomarker in DNA repair and aging

Toxicology in Vitro

Volumn 24, Issue 7, 2010, Pages 1935-1945

  Uday Bhanu, M ^a   Mandraju, R K ^a   Bhaskar, C ^a   Kondapi, Anand Kumar ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

Aging; Cerebellar granule neurons (CGNs); Intracellular Ca2+; NHEJ repair; Senescence associated beta galactosidase (SA gal); Topoisomerase II

Indexed keywords

BETA GALACTOSIDASE; BIOLOGICAL MARKER; CALCIUM ION; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE (ATP HYDROLYSING) ALPHA; ISOENZYME; KU ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CALCIUM CELL LEVEL; CELL AGING; CELL DEGENERATION; CELL VIABILITY; CEREBELLUM; CONTROLLED STUDY; DNA REPAIR; ENZYME ACTIVITY; EXCISION REPAIR; IN VITRO STUDY; NERVE CELL CULTURE; NONHUMAN; RAT; SENESCENCE;

AGING; ANIMALS; BETA-GALACTOSIDASE; BIOLOGICAL MARKERS; BRAIN; CALCIUM; CELL AGING; CEREBELLUM; DNA REPAIR; DNA TOPOISOMERASES, TYPE II; DNA-BINDING PROTEINS; MODELS, BIOLOGICAL; NEURONS; RATS; RATS, WISTAR;

EID: 77957018958     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.08.003     Document Type: Article

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