Regionally selective alterations in expression of the α1D subunit (Cav1.3) of L-type calcium channels in the hippocampus of aged rats

Molecular Brain Research

Volumn 107, Issue 2, 2002, Pages 120-127

  Veng, Lone M ^a   Browning, Michael D ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

1C; 1D; Aging; CA1; Hippocampus; L type calcium channel

Indexed keywords

CALCIUM CHANNEL L TYPE; PROTEIN; PROTEIN CA 1 3; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

AGED; AGING; ANIMAL TISSUE; ARTICLE; CALCIUM CURRENT; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING;

AGING; ANIMALS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; DENDRITES; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; NEURONAL PLASTICITY; PYRAMIDAL CELLS; RATS; RATS, INBRED F344; SYNAPTIC TRANSMISSION; UP-REGULATION;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0037111915     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(02)00453-9     Document Type: Article

References (45)

1. Araki T., Kato H., Shuto K., Itoyama Y. Age-related changes in [3H]nimodipine and [3H]rolipram binding in the rat brain. J. Pharm. Pharmacol. 49:1997;310-314.
2. Campbell L.W., Hao S.Y., Thibault O., Blalock E.M., Landfield P.W. Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons. J. Neurosci. 16:1996;6286-6295.
3. Catterall W.A. Structure and regulation of voltage-gated Ca2+ channels. Annu. Rev. Cell Dev. Biol. 16:2000;521-555.
4. Chen K.C., Blalock E.M., Thibault O., Kaminker P., Landfield P.W. Expression of alpha 1D subunit mRNA is correlated with L-type Ca2+ channel activity in single neurons of hippocampal 'zipper' slices. Proc. Natl. Acad. Sci. USA. 97:2000;4357-4362.
5. Clayton D.A., Browning M.D. Deficits in the expression of the NR2B subunit in the hippocampus of aged Fisher 344 rats. Neurobiol. Aging. 22:2001;165-168.
6. Clayton D.A., Mesches M.H., Alvarez E., Bickford P.C., Browning M.D. A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. J. Neurosci. 22:2002;3628-3637.
7. Cummings J.A., Mulkey R.M., Nicoll R.A., Malenka R.C. Ca2+ signaling requirements for long-term depression in the hippocampus. Neuron. 16:1996;825-833.
8. Dolmetsch R.E., Pajvani U., Fife K., Spotts J.M., Greenberg M.E. Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway. Science. 294:2001;333-339.
9. Ertel E.A., Campbell K.P., Harpold M.M., Hofmann F., Mori Y., Perez-Reyes E., Schwartz A., Snutch T.P., Tanabe T., Birnbaumer L., Tsien R.W., Catterall W.A. Nomenclature of voltage-gated calcium channels. Neuron. 25:2000;533-535.
10. Finkbeiner S., Greenberg M.E. Ca2+ channel-regulated neuronal gene expression. J. Neurobiol. 37:1998;171-189.
11. Foster T.C. Involvement of hippocampal synaptic plasticity in age-related memory decline. Brain Res. Brain Res. Rev. 30:1999;236-249.
12. Ghosh A., Greenberg M.E. Calcium signaling in neurons: molecular mechanisms and cellular consequences. Science. 268:1995;239-247.
13. Grover L.M., Teyler T.J. N-Methyl-D-aspartate receptor-independent long-term potentiation in area CA1 of rat hippocampus: input-specific induction and preclusion in a non-tetanized pathway. Neuroscience. 49:1992;7-11.
14. Grover L.M., Teyler T.J. Different mechanisms may be required for maintenance of NMDA receptor-dependent and independent forms of long-term potentiation. Synapse. 19:1995;121-133.
15. Hell J.W., Westenbroek R.E., Breeze L.J., Wang K.K., Chavkin C., Catterall W.A. N-Methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons. Proc. Natl. Acad. Sci. USA. 93:1996;3362-3367.
16. Hell J.W., Westenbroek R.E., Breeze L.J., Wang K.K., Chavkin C., Catterall W.A. N-Methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons. Proc. Natl. Acad. Sci. USA. 93:1996;3362-3367.
17. Hell J.W., Westenbroek R.E., Warner C., Ahlijanian M.K., Prystay W., Gilbert M.M., Snutch T.P., Catterall W.A. Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunits. J. Cell Biol. 123:1993;949-962.
18. Herman J.P., Chen K.C., Booze R., Landfield P.W. Up-regulation of alpha1D Ca2+ channel subunit mRNA expression in the hippocampus of aged F344 rats. Neurobiol. Aging. 19:1998;581-587.
19. Hockerman G.H., Peterson B.Z., Johnson B.D., Catterall W.A. Molecular determinants of drug binding and action on L-type calcium channels. Annu. Rev. Pharmacol. Toxicol. 37:1997;361-396.
20. Klugbauer N., Dai S., Specht V., Lacinova L., Marais E., Bohn G., Hofmann F. A family of gamma-like calcium channel subunits. FEBS Lett. 470:2000;189-197.
21. Koch W.J., Hui A., Shull G.E., Ellinor P., Schwartz A. Characterization of cDNA clones encoding two putative isoforms of the alpha 1 subunit of the dihydropyridine-sensitive voltage-dependent calcium channel isolated from rat brain and rat aorta. FEBS Lett. 250:1989;386-388.
22. Landfield P.W. Increased hippocampal Ca2+ channel activity in brain aging and dementia. Hormonal and pharmacologic modulation. Ann. NY Acad. Sci. 747:1994;351-364.
23. Landfield P.W., Pitler T.A. Prolonged Ca2+-dependent afterhyperpolarizations in hippocampal neurons of aged rats. Science. 226:1984;1089-1092.
24. Ludwig A., Flockerzi V., Hofmann F. Regional expression and cellular localization of the alpha1 and beta subunit of high voltage-activated calcium channels in rat brain. J. Neurosci. 17:1997;1339-1349.
25. Marrion N.V., Tavalin S.J. Selective activation of Ca2+-activated K+ channels by co-localized Ca2+ channels in hippocampal neurons. Nature. 395:1998;900-905.
26. Moyer J.R. Jr., Disterhoft J.F. Nimodipine decreases calcium action potentials in rabbit hippocampal CA1 neurons in an age-dependent and concentration-dependent manner. Hippocampus. 4:1994;11-17.
27. Moyer J.R. Jr., Thompson L.T., Black J.P., Disterhoft J.F. Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner. J. Neurophysiol. 68:1992;2100-2109.
28. Mulkey R.M., Malenka R.C. Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus. Neuron. 9:1992;967-975.
29. Nicolle M.M., Gallagher M., McKinney M. No loss of synaptic proteins in the hippocampus of aged, behaviorally impaired rats. Neurobiol. Aging. 20:1999;343-348.
30. Norris C.M., Halpain S., Foster T.C. Alterations in the balance of protein kinase/phosphatase activities parallel reduced synaptic strength during aging. J. Neurophysiol. 80:1998;1567-1570.
31. Norris C.M., Halpain S., Foster T.C. Reversal of age-related alterations in synaptic plasticity by blockade of L-type Ca2+ channels. J. Neurosci. 18:1998;3171-3179.
32. Norris C.M., Korol D.L., Foster T.C. Increased susceptibility to induction of long-term depression and long-term potentiation reversal during aging. J. Neurosci. 16:1996;5382-5392.
33. Peterson B.Z., Johnson B.D., Hockerman G.H., Acheson M., Scheuer T., Catterall W.A. Analysis of the dihydropyridine receptor site of L-type calcium channels by alanine-scanning mutagenesis. J. Biol. Chem. 272:1997;18752-18758.
34. Rapp P.R., Gallagher M. Preserved neuron number in the hippocampus of aged rats with spatial learning deficits. Proc. Natl. Acad. Sci. USA. 93:1996;9926-9930.
35. Segal M. Fast imaging of [Ca]i reveals presence of voltage-gated calcium channels in dendritic spines of cultured hippocampal neurons. J. Neurophysiol. 74:1995;484-488.
36. Shankar S., Teyler T.J., Robbins N. Aging differentially alters forms of long-term potentiation in rat hippocampal area CA1. J. Neurophysiol. 79:1998;334-341.
37. Snutch T.P., Leonard J.P., Gilbert M.M., Lester H.A., Davidson N. Rat brain expresses a heterogeneous family of calcium channels. Proc. Natl. Acad. Sci. USA. 87:1990;3391-3395.
38. Takahashi M., Catterall W.A. Identification of an alpha subunit of dihydropyridine-sensitive brain calcium channels. Science. 236:1987;88-91.
39. Teyler T.J., Cavus I., Coussens C., DiScenna P., Grover L., Lee Y.P., Little Z. Multideterminant role of calcium in hippocampal synaptic plasticity. Hippocampus. 4:1994;623-634.
40. Thibault O., Hadley R., Landfield P.W. Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. J. Neurosci. 21:2001;9744-9756.
41. Thibault O., Landfield P.W. Increase in single L-type calcium channels in hippocampal neurons during aging. Science. 272:1996;1017-1020.
42. Thibault O., Porter N.M., Chen K.C., Blalock E.M., Kaminker P.G., Clodfelter G.V., Brewer L.D., Landfield P.W. Calcium dysregulation in neuronal aging and Alzheimer's disease: history and new directions. Cell Calcium. 24:1998;417-433.
43. Watson R.E. Jr., Wiegand S.J., Clough R.W., Hoffman G.E. Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology. Peptides. 7:1986;155-159.
44. Wei X., Neely A., Lacerda A.E., Olcese R., Stefani E., Perez-Reyes E., Birnbaumer L. Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit. J. Biol. Chem. 269:1994;1635-1640.
45. Xu W., Lipscombe D. Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines. J. Neurosci. 21:2001;5944-5951.