In vivo fluorescence-mediated tomography for quantification of urokinase receptor-dependent leukocyte trafficking in inflammation

Anesthesiology

Volumn 113, Issue 3, 2010, Pages 610-618

  Larmann, Jan ^a   Frenzel, Tim ^a,b   Hahnenkamp, Anke ^a,c   Herzog, Christine ^a   Lorenz, Anika ^a   Steinbicker, Andrea U ^a,b   Calmer, Simone ^a   Harendza, Thomas ^a   Schmitz, Martina ^a,c   Echtermeyer, Frank ^a   Hildebrand, Reinhard ^a,c   Bremer, Christoph ^a,c   Theilmeier, Gregor ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Interdisciplinary Center for Clinical Research   (Germany)

^c UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

UROKINASE RECEPTOR; AUTACOID; DIACETYLDICHLOROFLUORESCEIN; DIAGNOSTIC AGENT; FLUORESCEIN DERIVATIVE; FLUORESCENT DYE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; IN VIVO STUDY; LEUKOCYTE ADHERENCE; LUNG GAS EXCHANGE; MACROPHAGE MIGRATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERITONITIS; PNEUMONIA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEPTIC SHOCK; ANIMAL; C57BL MOUSE; CELL LINE; CELL MOTION; COMPARATIVE STUDY; CYTOLOGY; GENETICS; METABOLISM; METHODOLOGY; MOUSE MUTANT; PATHOLOGY; PERITONEUM MACROPHAGE; PHYSIOLOGY; PROTEIN TRANSPORT; TOMOGRAPHY; TRANSGENIC MOUSE; VASCULAR ENDOTHELIUM;

ANIMALS; CELL LINE, TRANSFORMED; CELL MOVEMENT; ENDOTHELIUM, VASCULAR; FLUORESCEINS; FLUORESCENT DYES; INFLAMMATION MEDIATORS; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUTROPHIL INFILTRATION; PERITONITIS; PROTEIN TRANSPORT; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; TOMOGRAPHY;

EID: 77957011174     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e3181e99bfc     Document Type: Article

References (42)

1. Brown KA, Brain SD, Pearson JD, Edgeworth JD, Lewis SM, Treacher DF: Neutrophils in development of multiple organ failure in sepsis. Lancet 2006; 368:157-169
2. Hibbs ML, Xu H, Stacker SA, Springer TA: Regulation of adhesion of ICAM-1 by the cytoplasmic domain of LFA-1 integrin beta subunit. Science 1991; 251:1611-1613
3. Butcher EC: Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity. Cell 1991; 67:1033-1036
4. Conway EM, Van de Wouwer M, Pollefeyt S, Jurk K, Van Aken H, De Vriese A, Weitz JI, Weiler H, Hellings PW, Schaeffer P, Herbert JM, Collen D, Theilmeier G: The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways. J Exp Med 2002; 196:565-577
5. Kunkel EJ, Butcher EC: Plasma-cell homing. Nat Rev Immunol 2003; 3:822-829
6. Larmann J, Schmidt C, Gammelin H, Van Aken HK, Frenzel T, Lanckohr C, Lox M, Boese N, Jurk K, Theilmeier G: Intercellular adhesion molecule-1 inhibition attenuates neurologic and hepatic damage after resuscitation in mice. ANESTHESIOLOGY 2005; 103:1149-1155
7. Larmann J, Theilmeier G: Inflammatory response to cardiac surgery: Cardiopulmonary bypass versus non-cardiopulmonary bypass surgery. Best Pract Res Clin Anaesthesiol 2004; 18:425-438
8. Lehmann JC, Jablonski-Westrich D, Haubold U, Gutierrez- Ramos JC, Springer T, Hamann A: Overlapping and selective roles of endothelial intercellular adhesion molecule-1 (ICAM-1) and ICAM-2 in lymphocyte trafficking. J Immunol 2003; 171:2588-2593
9. Luo BH, Carman CV, Springer TA: Structural basis of integrin regulation and signaling. Annu Rev Immunol 2007; 25:619-647
10. Phan UT, Waldron TT, Springer TA: Remodeling of the lectin-EGF-like domain interface in P- and L-selectin increases adhesiveness and shear resistance under hydrodynamic force. Nat Immunol 2006; 7:883-889
11. Slack SM, Turitto VT: Flow chambers and their standardization for use in studies of thrombosis. On behalf of the Subcommittee on Rheology of the Scientific and Standardization Committee of the ISTH. Thromb Haemost 1994; 72:777-781
12. Suzuki A, Andrew DP, Gonzalo JA, Fukumoto M, Spellberg J, Hashiyama M, Takimoto H, Gerwin N, Webb I, Molineux G, Amakawa R, Tada Y, Wakeham A, Brown J, McNiece I, Ley K, Butcher EC, Suda T, Gutierrez-Ramos JC, Mak TW: CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein. Blood 1996; 87:3550-3562
13. Theilmeier G, Michiels C, Spaepen E, Vreys I, Collen D, Vermylen J, Hoylaerts MF: Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia. Blood 2002; 99:4486-4493
14. Theilmeier G, Schmidt C, Herrmann J, Keul P, Schäfers M, Herrgott I, Mersmann J, Larmann J, Hermann S, Stypmann J, Schober O, Hildebrand R, Schulz R, Heusch G, Haude M, von Wnuck Lipinski K, Herzog C, Schmitz M, Erbel R, Chun J, Levkau B: High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor. Circulation 2006; 114: 1403-1409
15. Bellingan GJ, Xu P, Cooksley H, Cauldwell H, Shock A, Bottoms S, Haslett C, Mutsaers SE, Laurent GJ: Adhesion molecule-dependent mechanisms regulate the rate of macrophage clearance during the resolution of peritoneal inflammation. J Exp Med 2002; 196:1515-1521
16. Bellingan GJ, Caldwell H, Howie SE, Dransfield I, Haslett C: In vivo fate of the inflammatory macrophage during the resolution of inflammation: Inflammatory macrophages do not die locally, but emigrate to the draining lymph nodes. J Immunol 1996; 157:2577-2585
17. Cao C, Lawrence DA, Strickland DK, Zhang L: A specific role of integrin Mac-1 in accelerated macrophage efflux to the lymphatics. Blood 2005; 106:3234-3241
18. May AE, Kanse SM, Lund LR, Gisler RH, Imhof BA, Preissner KT: Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo. J Exp Med 1998; 188:1029-1037
19. Springer TA: Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain. Proc Natl Acad Sci U S A 1997; 94:65-72
20. Blasi F, Carmeliet P: uPAR: A versatile signalling orchestrator. Nat Rev Mol Cell Biol 2002; 3:932-943
21. Bolick DT, Whetzel AM, Skaflen M, Deem TL, Lee J, Hedrick CC: Absence of the G protein-coupled receptor G2A in mice promotes monocyte/endothelial interactions in aorta. Circ Res 2007; 100:572-580
22. Sperandio M, Pickard J, Unnikrishnan S, Acton ST, Ley K: Analysis of leukocyte rolling in vivo and in vitro. Methods Enzymol 2006; 416:346-371
23. Theilmeier G, Lenaerts T, Remacle C, Collen D, Vermylen J, Hoylaerts MF: Circulating activated platelets assist THP-1 monocytoid/endothelial cell interaction under shear stress. Blood 1999; 94:2725-2734
24. Mempel TR, Scimone ML, Mora JR, von Andrian UH: In vivo imaging of leukocyte trafficking in blood vessels and tissues. Curr Opin Immunol 2004; 16:406-417
25. Padera TP, Stoll BR, So PT, Jain RK: Conventional and high-speed intravital multiphoton laser scanning microscopy of microvasculature, lymphatics, and leukocyte-endothelial interactions. Mol Imaging 2002; 1:9-15
26. 3 integrin-targeted fluorochrome. J Nucl Med 2008; 49:1845-1851
27. Bremer C, Tung CH, Weissleder R: In vivo molecular target assessment of matrix metalloproteinase inhibition. Nat Med 2001; 7:743-748
28. Ntziachristos V, Tung CH, Bremer C, Weissleder R: Fluorescence molecular tomography resolves protease activity in vivo. Nat Med 2002; 8:757-760
29. Ntziachristos V, Weissleder R: Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media. Med Phys 2002; 29:803-809
30. Dewerchin M, Nuffelen AV, Wallays G, Bouché A, Moons L, Carmeliet P, Mulligan RC, Collen D: Generation and characterization of urokinase receptor-deficient mice. J Clin Invest 1996; 97:870-878
31. Patel SS, Thiagarajan R, Willerson JT, Yeh ET: Inhibition of alpha4 integrin and ICAM-1 markedly attenuate macrophage homing to atherosclerotic plaques in ApoE-deficient mice. Circulation 1998; 97:75-81
32. Kaczmarek DJ, Herzog C, Larmann J, Gillmann HJ, Hildebrand R, Schmitz M, Westermann A, Harendza T, Werdehausen R, Osthaus AW, Echtermeyer F, Hahnenkamp K, Wollert KC, Theilmeier G: Lidocaine protects from myocardial damage due to ischemia and reperfusion in mice by its antiapoptotic effects. ANESTHESIOLOGY 2009; 110:1041-1049
33. Rosenkranz AR, Schmaldienst S, Stuhlmeier KM, Chen W, Knapp W, Zlabinger GJ: A microplate assay for the detection of oxidative products using 2',7'-dichlorofluorescindiacetate. J Immunol Methods 1992; 156:39-45
34. Graves EE, Yessayan D, Turner G, Weissleder R, Ntziachristos V: Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography. J Biomed Opt 2005; 10:44019
35. Pasceri V, Wu HD, Willerson JT, Yeh ET: Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators. Circulation 2000; 101:235-238
36. Deguchi JO, Aikawa M, Tung CH, Aikawa E, Kim DE, Ntziachristos V, Weissleder R, Libby P: Inflammation in atherosclerosis: Visualizing matrix metalloproteinase action in macrophages in vivo. Circulation 2006; 114:55-62
37. Chen JW, Querol Sans M, Bogdanov A Jr, Weissleder R: Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates. Radiology 2006; 240: 473-481
38. Kaufmann BA, Sanders JM, Davis C, Xie A, Aldred P, Sarembock IJ, Lindner JR: Molecular imaging of inflammation in atherosclerosis with targeted ultrasound detection of vascular cell adhesion molecule-1. Circulation 2007; 116:276-284
39. Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R: Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis. Circulation 2006; 114:1504-1511
40. Erickson SJ, Godavarty A: Hand-held based near-infrared optical imaging devices: A review. Med Eng Phys 2009; 31:495-509
41. Chin WW, Thong PS, Bhuvaneswari R, Soo KC, Heng PW, Olivo M: In-vivo optical detection of cancer using chlorin e6 -polyvinylpyrrolidone induced fluorescence imaging and spectroscopy. BMC Med Imaging 2009; 9:1-13
42. Honig MG, Hume RI: Fluorescent carbocyanine dyes allow living neurons of identified origin to be studied in longterm cultures. J Cell Biol 1986; 103:171-187