High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor

Circulation

Volumn 114, Issue 13, 2006, Pages 1403-1409

  Theilmeier, Gregor ^a   Schmidt, Christoph ^a   Herrmann, Jörg ^b   Keul, Petra ^c   Schäfers, Michael ^a   Herrgott, Ilka ^a   Mersmann, Jan ^a   Larmann, Jan ^a   Hermann, Sven ^a   Stypmann, Jörg ^a   Schober, Otmar ^a   Hildebrand, Reinhard ^a   Schulz, Rainer ^c   Heusch, Gerd ^c   Haude, Michael ^c   Lipinski, Karin Von Wnuck ^c   Herzog, Christine ^a   Schmitz, Martina ^a   Erbel, Raimund ^c   Chun, Jerold ^d   Levkau, Bodo ^c   more..

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b MAYO CLINIC   (United States)

^c UNIVERSITY HOSPITAL ESSEN   (Germany)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Apoptosis; Endothelium; Inflammation; Lipoproteins; Microcirculation; Reperfusion; Sphingolipids

Indexed keywords

HIGH DENSITY LIPOPROTEIN; LYSOPHOSPHOLIPID RECEPTOR; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; IN VIVO STUDY; LEUKOCYTE ADHERENCE INHIBITION; LEUKOCYTE MIGRATION INHIBITION; MOUSE; NEUTROPHIL CHEMOTAXIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN SYNTHESIS INHIBITION; REPERFUSION INJURY; THERAPY EFFECT;

ANIMALS; APOPTOSIS; CARDIOTONIC AGENTS; CELL ADHESION; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; ENDOTHELIAL CELLS; FEMALE; HUMANS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; LYSOPHOSPHOLIPIDS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RECEPTORS, LYSOSPHINGOLIPID; SPHINGOSINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33749012804     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.105.607135     Document Type: Article

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