Comparison of beta-catenin with TGF-beta1, HIF-1alpha and patients' disease-free survival in human colorectal cancer

Pathology and Oncology Research

Volumn 16, Issue 3, 2010, Pages 311-318

  Wincewicz, Andrzej ^a   Koda, Mariusz ^a   Sulkowski, Stanislaw ^a   Kanczuga Koda, Luiza ^a   Sulkowska, Mariola ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Beta catenin; Colorectal cancer; HIF 1alpha; Patients' disease free survival; TGF beta1

Indexed keywords

BETA CATENIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; KI 67 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ARTICLE; CANCER CELL; CANCER PATIENT; CANCER SURVIVAL; CANCER TISSUE; CLINICAL FEATURE; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE FREE SURVIVAL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION;

BETA CATENIN; COLORECTAL NEOPLASMS; DISEASE-FREE SURVIVAL; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; NEOPLASM STAGING; TRANSFORMING GROWTH FACTOR BETA1; TUMOR MARKERS, BIOLOGICAL;

EID: 77956875346     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12253-009-9217-2     Document Type: Article

References (30)

1. NA Wong M Pignatelli 2002 Beta-catenin-a linchpin in colorectal carcinogenesis? Am J Pathol 160 389 401 1:CAS:528:DC%2BD38XitVClu74%3D 11839557
2. M Lüchtenborg MP Weijenberg PA Wark AM Saritas GM Roemen GN van Muijen AP de Bruïne PA van den Brandt AF de Goeij 2005 Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study BMC Cancer 5 160 10.1186/1471-2407-5-160 16356174
3. Sulkowska M, Wincewicz A, Sulkowski S, Koda M, Kanczuga-Koda L (2009) Relations of TGF-beta1 with HIF-1alpha, GLUT-1 and longer survival of colorectal cancer patients. Pathology Jan 13:1-7. [Epub ahead of print]
4. J Xu L Attisano 2000 Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway Proc Natl Acad Sci USA 97 4820 4825 1:CAS:528:DC%2BD3cXivFKjuro%3D 10.1073/pnas.97.9.4820 10781087
5. F Li Y Cao CM Townsend Jr TC Ko 2005 TGF-beta signaling in colon cancer cells World J Surg 29 306 311 10.1007/s00268-004-7813-6 15711891
6. D Bacman S Merkel R Croner T Papadopoulos W Brueckl A Dimmler 2007 TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study BMC Cancer 7 156 10.1186/1471-2407-7-156 17692120
7. RH Giles MP Lolkema CM Snijckers M Belderbos P van der Groep DA Mans M van Beest M van Noort R Goldschmeding PJ van Diest H Clevers EE Voest 2006 Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis Oncogene 25 3065 3070 1:CAS:528:DC%2BD28Xks1OrsLg%3D 10.1038/sj.onc.1209330 16407833
8. M de la Roche J Worm M Bienz 2008 The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells BMC Cancer 8 199 10.1186/1471-2407-8-199 18627596
9. JH Lim YS Chun JW Park 2008 Hypoxia-inducible factor-1alpha obstructs a Wnt signaling pathway by inhibiting the hARD1-mediated activation of beta-catenin Cancer Res 68 5177 5184 1:CAS:528:DC%2BD1cXnvFyjsro%3D 10.1158/0008-5472.CAN-07-6234 18593917
10. LN Li HD Zhang SJ Yuan ZY Tian L Wang ZX Sun 2007 Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway Int J Cancer 121 1360 1365 1:CAS:528: DC%2BD2sXhtVSmtL%2FK 10.1002/ijc.22804 17520675
11. A Kaidi AC Williams C Paraskeva 2007 Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia Nat Cell Biol 9 210 217 1:CAS:528:DC%2BD2sXhtFGlsbY%3D 10.1038/ncb1534 17220880
12. A Wincewicz M Sulkowska M Koda S Sulkowski 2007 Cumulative expression of HIF-1-alpha, Bax, Bcl-xL and P53 in human colorectal cancer Pathology 39 334 338 1:CAS:528:DC%2BD2sXmt1ant7c%3D 10.1080/00313020701329765 17558861
13. A Wincewicz M Sulkowska M Koda S Sulkowski 2007 Clinicopathological significance and linkage of the distribution of HIF-1alpha and GLUT-1 in human primary colorectal cancer Pathol Oncol Res 13 15 20 1:CAS:528: DC%2BD2sXntFOlsbo%3D 10.1007/BF02893436 17387384
14. H Wang M Promkan G Liu S Chakrabarty 2008 Switch of transforming growth factor beta function from tumor suppression to stimulation in adenomatous polyposis coli (APC) knocked-down human colon carcinoma cells Cancer Lett 272 253 259 1:CAS:528:DC%2BD1cXhtlyhtrzP 10.1016/j.canlet.2008.07.010 18774639
15. H Wang S Rajan G Liu S Chakrabarty 2008 Transforming growth factor beta suppresses beta-catenin/Wnt signaling and stimulates an adhesion response in human colon carcinoma cells in a Smad4/DPC4 independent manner Cancer Lett 264 281 287 1:CAS:528:DC%2BD1cXlslSitr0%3D 10.1016/j.canlet.2008.01.039 18367323
16. DL Lambie IS Brown 2008 Multinucleate epithelial change in colorectal hyperplastic polyps: a review of 27 cases J Clin Pathol 61 611 614 1:STN:280:DC%2BD1c3nsFCguw%3D%3D 10.1136/jcp.2007.050849 18037663
17. J Settakorn N Kaewpila GF Burns AS Leong 2005 FAT, E-cadherin, beta catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinoma J Clin Pathol 58 1249 1254 1:CAS:528: DC%2BD28Xjs1Gjsg%3D%3D 10.1136/jcp.2005.026575 16311342
18. RT Pirinen P Hirvikoski RT Johansson S Hollmén VM Kosma 2001 Reduced expression of alpha-catenin, beta-catenin, and gamma-catenin is associated with high cell proliferative activity and poor differentiation in non-small cell lung cancer J Clin Pathol 54 391 395 1:STN:280: DC%2BD3M3mt12isA%3D%3D 10.1136/jcp.54.5.391 11328840
19. SC Wong AT Chan JK Chan YM Lo 2006 Nuclear beta-catenin and Ki-67 expression in choriocarcinoma and its pre-malignant form J Clin Pathol 59 387 392 1:CAS:528:DC%2BD28XktVajsL0%3D 10.1136/jcp.2005.026666 16467170
20. K Takeda I Kinoshita Y Shimizu Y Ohba T Itoh Y Matsuno T Shichinohe H Dosaka-Akita 2008 Clinicopathological significance of expression of p-c-Jun, TCF4 and beta-catenin in colorectal tumors BMC Cancer 8 328 10.1186/1471-2407-8- 328 18992165
21. YW Tien YM Jeng RH Hu KJ Chang SM Hsu PH Lee 2004 Intravasation-related metastatic factors in colorectal cancer Tumour Biol 25 48 55 1:CAS:528:DC%2BD2cXksl2nsrs%3D 10.1159/000077723 15192312
22. N Pećina-Slaus T Niku Eva-Martić V Beros, et al. 2007 Genetic alterations of E-cadherin and beta-catenin in germinoma and teratoma: report of two central nervous system cases Pathol Oncol Res 13 370 374 10.1007/BF02940319 18158575
23. Kabukcuoglu F, Kabukcuoglu Y, Tanik C et al (2008) Breast carcinoma metastasis in recurrent myxoid liposarcoma. Pathol Oncol Res
24. Horst D, Kriegl L, Engel J et al (2009) CD133 and nuclear beta-catenin: the marker combination to detect high risk cases of low stage colorectal cancer. Eur J Cancer
25. D Horst S Reu L Kriegl, et al. 2009 The intratumoral distribution of nuclear beta-catenin is a prognostic marker in colon cancer Cancer 115 2063 2070 10.1002/cncr.24254 19298008
26. J Bondi G Bukholm JM Nesland A Bakka IR Bukholm 2006 An increase in the number of adhesion proteins with altered expression is associated with an increased risk of cancer death for colon carcinoma patients Int J Colorectal Dis 21 231 237 10.1007/s00384-005-0762-1 15937692
27. G Canavese A Bernardi G Candelaresi P Lovadina S Amerio V Rossetti C Rabagliati E Berardengo 2007 Expression of the E-cadherin-catenins complex in sentinel node is related to tumor morphology but not to spread to nonsentinel nodes Pathol Res Pract 203 517 523 10.1016/j.prp.2007.03.003 17576040
28. Stewart CJ, Crook ML, Leung YC, Platten M (2009) Expression of cell cycle regulatory proteins in endometrial adenocarcinoma: variations in conventional tumor areas and in microcystic, elongated and fragmented glands. Mod Pathol, Mar 6. [Epub ahead of print]
29. S Nagayama E Yamada Y Kohno T Aoyama C Fukukawa H Kubo G Watanabe T Katagiri Y Nakamura Y Sakai J Toguchida 2009 Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors Cancer Sci 100 405 412 1:CAS:528: DC%2BD1MXjt1WrtLw%3D 10.1111/j.1349-7006.2008.01052.x 19134005
30. ST Mees R Mennigen T Spieker E Rijcken N Senninger J Haier M Bruewer 2009 Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and beta-catenin Int J Colorectal Dis 24 361 368 1:STN:280: DC%2BD1M7mt12qug%3D%3D 10.1007/s00384-009-0653-y 19184060