-
1
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
Wang GL, Semenza GL. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem 1995; 270: 1230-7.
-
(1995)
J Biol Chem
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
2
-
-
0029051439
-
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
Wang GL, Jiang BH, Rue EA, et al. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995; 92: 5510-4.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
-
3
-
-
0032478823
-
Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression
-
Wood SM, Wiesener MS, Yeates KM, et al. Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression. J Biol Chem 1998; 273: 8360-8.
-
(1998)
J Biol Chem
, vol.273
, pp. 8360-8368
-
-
Wood, S.M.1
Wiesener, M.S.2
Yeates, K.M.3
-
4
-
-
1642387020
-
Hypoxia-inducible factor (HIF-1)alpha: Its protein stability and biological functions
-
Lee JW, Bae SH, Jeong JW, et al. Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions. Exp Mol Med 2004; 36: 1-12.
-
(2004)
Exp Mol Med
, vol.36
, pp. 1-12
-
-
Lee, J.W.1
Bae, S.H.2
Jeong, J.W.3
-
5
-
-
0035884701
-
HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
-
Sowter HM, Ratcliffe PJ, Watson P, et al. HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res 2001; 61: 6669-73.
-
(2001)
Cancer Res
, vol.61
, pp. 6669-6673
-
-
Sowter, H.M.1
Ratcliffe, P.J.2
Watson, P.3
-
6
-
-
33745947446
-
Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer
-
Koukourakis MI, Giatromanolaki A, Polychronidis A, et al. Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer. Cancer Sci 2006; 97: 582-8.
-
(2006)
Cancer Sci
, vol.97
, pp. 582-588
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Polychronidis, A.3
-
7
-
-
0033222349
-
Killing of brain tumor cells by hypoxia-responsive element mediated expression of BAX
-
Ruan H, Wang J, Hu L, et al. Killing of brain tumor cells by hypoxia-responsive element mediated expression of BAX. Neoplasia 1999; 1: 431-7.
-
(1999)
Neoplasia
, vol.1
, pp. 431-437
-
-
Ruan, H.1
Wang, J.2
Hu, L.3
-
8
-
-
18244406785
-
Functionality of hypoxia-induced BAX expression in a human glioblastoma xenograft model
-
Ozawa T, Hu JL, Hu LJ, et al. Functionality of hypoxia-induced BAX expression in a human glioblastoma xenograft model. Cancer Gene Ther 2005; 12: 449-55.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 449-455
-
-
Ozawa, T.1
Hu, J.L.2
Hu, L.J.3
-
9
-
-
0032581277
-
Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
Carmeliet P, Dor Y, Herbert JM, et al. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature 1998; 394: 485-90.
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
Dor, Y.2
Herbert, J.M.3
-
10
-
-
19944434232
-
Differential prognostic impact of hypoxia induced and diffuse HIF-1alpha expression in invasive breast cancer
-
Vleugel MM, Greijer AE, Shvarts A, et al. Differential prognostic impact of hypoxia induced and diffuse HIF-1alpha expression in invasive breast cancer. J Clin Pathol 2005; 58: 172-7.
-
(2005)
J Clin Pathol
, vol.58
, pp. 172-177
-
-
Vleugel, M.M.1
Greijer, A.E.2
Shvarts, A.3
-
11
-
-
11144222884
-
Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: Correlation with tumor angiogenesis and cyclooxygenase-2 expression
-
Yoshimura H, Dhar DK, Kohno H, et al. Prognostic impact of hypoxia-inducible factors 1alpha and 2alpha in colorectal cancer patients: correlation with tumor angiogenesis and cyclooxygenase-2 expression. Clin Cancer Res 2004; 10: 8554-60.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8554-8560
-
-
Yoshimura, H.1
Dhar, D.K.2
Kohno, H.3
-
12
-
-
0033094311
-
Prognostic significance of Bcl-2, Bcl-xL/S, Bax and Bak expressions in colorectal carcinomas
-
Ogura E, Senzaki H, Yamamoto D, et al. Prognostic significance of Bcl-2, Bcl-xL/S, Bax and Bak expressions in colorectal carcinomas. Oncol Rep 1999; 6: 365-9.
-
(1999)
Oncol Rep
, vol.6
, pp. 365-369
-
-
Ogura, E.1
Senzaki, H.2
Yamamoto, D.3
-
13
-
-
0036605086
-
Analysis of P53/BAX in primary colorectal carcinoma: Low BAX protein expression is a negative prognostic factor in UICC stage III tumors
-
Schelwies K, Sturm I, Grabowski P, et al. Analysis of P53/BAX in primary colorectal carcinoma: low BAX protein expression is a negative prognostic factor in UICC stage III tumors. Int J Cancer 2002; 99: 589-96.
-
(2002)
Int J Cancer
, vol.99
, pp. 589-596
-
-
Schelwies, K.1
Sturm, I.2
Grabowski, P.3
-
14
-
-
19944376103
-
Low BAX protein expression correlates with disease recurrence in preoperatively irradiated rectal carcinoma
-
Nehls O, Okech T, Hsieh CJ, et al. Low BAX protein expression correlates with disease recurrence in preoperatively irradiated rectal carcinoma. Int J Radiat Oncol Biol Phys 2005; 61: 85-91.
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.61
, pp. 85-91
-
-
Nehls, O.1
Okech, T.2
Hsieh, C.J.3
-
15
-
-
0031875003
-
Expression of hypoxia-inducible genes in tumor cells
-
Kress S, Stein A, Maurer P, et al. Expression of hypoxia-inducible genes in tumor cells. J Cancer Res Clin Oncol 1998; 124: 315-20.
-
(1998)
J Cancer Res Clin Oncol
, vol.124
, pp. 315-320
-
-
Kress, S.1
Stein, A.2
Maurer, P.3
-
16
-
-
32144464204
-
P53 correlates positively with VEGF in preoperative sera of colorectal cancer patients
-
Famulski W, Sulkowska M, Wincewicz A, et al. P53 correlates positively with VEGF in preoperative sera of colorectal cancer patients. Neoplasma 2006; 53: 43-8.
-
(2006)
Neoplasma
, vol.53
, pp. 43-48
-
-
Famulski, W.1
Sulkowska, M.2
Wincewicz, A.3
-
17
-
-
31544445490
-
Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: A metabolic survival role for tumor-associated stroma
-
Koukourakis MI, Giatromanolaki A, Harris AL, et al. Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma. Cancer Res 2006; 66: 632-7.
-
(2006)
Cancer Res
, vol.66
, pp. 632-637
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Harris, A.L.3
-
18
-
-
0036678830
-
Two sequence motifs from HIF-1alpha bind to the DNA-binding site of P53
-
Hansson LO, Friedler A, Freund S, et al. Two sequence motifs from HIF-1alpha bind to the DNA-binding site of P53. Proc Natl Acad Sci USA 2002; 99: 10305-9.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10305-10309
-
-
Hansson, L.O.1
Friedler, A.2
Freund, S.3
-
19
-
-
0038529602
-
Direct interactions between HIF-1 alpha and Mdm2 modulate P53 function
-
Chen D, Li M, Luo J, et al. Direct interactions between HIF-1 alpha and Mdm2 modulate P53 function. J Biol Chem 2003; 278: 13595-8.
-
(2003)
J Biol Chem
, vol.278
, pp. 13595-13598
-
-
Chen, D.1
Li, M.2
Luo, J.3
-
20
-
-
0032568150
-
Stabilization of wild-type P53 by hypoxia-inducible factor 1alpha
-
An WG, Kanekal M, Simon MC, et al. Stabilization of wild-type P53 by hypoxia-inducible factor 1alpha. Nature 1998; 392: 405-8.
-
(1998)
Nature
, vol.392
, pp. 405-408
-
-
An, W.G.1
Kanekal, M.2
Simon, M.C.3
-
21
-
-
4544224808
-
Influences of the P53 status on hypoxia-induced gene expression
-
Liu J, Shibata T, Qu R, et al. Influences of the P53 status on hypoxia-induced gene expression. J Radiat Res 2004; 45: 333-9.
-
(2004)
J Radiat Res
, vol.45
, pp. 333-339
-
-
Liu, J.1
Shibata, T.2
Qu, R.3
-
22
-
-
33746071114
-
p300 and P53 levels determine activation of HIF-1 downstream targets in invasive breast cancer
-
Vleugel MM, Shvarts D, van der Wall E, van Diest PJ. p300 and P53 levels determine activation of HIF-1 downstream targets in invasive breast cancer. Hum Pathol 2006; 37: 1085-92.
-
(2006)
Hum Pathol
, vol.37
, pp. 1085-1092
-
-
Vleugel, M.M.1
Shvarts, D.2
van der Wall, E.3
van Diest, P.J.4
-
23
-
-
33745868751
-
Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis: Involvement of mitochondrial inhibition and P53 suppression
-
Wang J, Biju MP, Wang MH, et al. Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis: involvement of mitochondrial inhibition and P53 suppression. J Am Soc Nephrol 2006; 17: 1875-85.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1875-1885
-
-
Wang, J.1
Biju, M.P.2
Wang, M.H.3
-
24
-
-
12144287046
-
Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance
-
Erler JT, Cawthorne CJ, Williams KJ, et al. Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance. Mol Cell Biol 2004; 24: 2875-89.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2875-2889
-
-
Erler, J.T.1
Cawthorne, C.J.2
Williams, K.J.3
-
25
-
-
23844540031
-
Mechanism of HIF-1alpha-dependent suppression of hypoxia-induced apoptosis in squamous cell carcinoma cells
-
Sasabe E, Tatemoto Y, Li D, et al. Mechanism of HIF-1alpha-dependent suppression of hypoxia-induced apoptosis in squamous cell carcinoma cells. Cancer Sci 2005; 96: 394-402.
-
(2005)
Cancer Sci
, vol.96
, pp. 394-402
-
-
Sasabe, E.1
Tatemoto, Y.2
Li, D.3
-
26
-
-
4344669774
-
Bimodal effect of hypoxia in cancer: Role of hypoxia inducible factor in apoptosis
-
Wang Y, Pakunlu RI, Tsao W, et al. Bimodal effect of hypoxia in cancer: role of hypoxia inducible factor in apoptosis. Mol Pharm 2004; 1: 156-65.
-
(2004)
Mol Pharm
, vol.1
, pp. 156-165
-
-
Wang, Y.1
Pakunlu, R.I.2
Tsao, W.3
-
27
-
-
33644786231
-
Antitumor activity and down-regulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound
-
Teraishi F, Wu S, Inoue S, et al. Antitumor activity and down-regulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound. Prostate 2006; 66: 430-8.
-
(2006)
Prostate
, vol.66
, pp. 430-438
-
-
Teraishi, F.1
Wu, S.2
Inoue, S.3
-
28
-
-
26244432793
-
Proliferating fibroblasts at the invading tumour edge of colorectal adenocarcinomas are associated with endogenous markers of hypoxia, acidity, and oxidative stress
-
Sivridis E, Giatromanolaki A, Koukourakis MI. Proliferating fibroblasts at the invading tumour edge of colorectal adenocarcinomas are associated with endogenous markers of hypoxia, acidity, and oxidative stress. J Clin Pathol 2005; 58: 1033-8.
-
(2005)
J Clin Pathol
, vol.58
, pp. 1033-1038
-
-
Sivridis, E.1
Giatromanolaki, A.2
Koukourakis, M.I.3
-
29
-
-
11144221595
-
Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha
-
Yoo YG, Yeo MG, Kim DK, Park H, Lee MO. Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha. J Biol Chem 2004; 279: 53365-73.
-
(2004)
J Biol Chem
, vol.279
, pp. 53365-53373
-
-
Yoo, Y.G.1
Yeo, M.G.2
Kim, D.K.3
Park, H.4
Lee, M.O.5
-
30
-
-
0028984843
-
Bcl-xL and Bcl-2 repress a common pathway of cell death
-
Chao DT, Linette GP, Boise LH, et al. Bcl-xL and Bcl-2 repress a common pathway of cell death. J Exp Med 1995; 182: 821-8.
-
(1995)
J Exp Med
, vol.182
, pp. 821-828
-
-
Chao, D.T.1
Linette, G.P.2
Boise, L.H.3
-
31
-
-
0033799480
-
Heterodimerization of Bcl-2 and Bcl-X(L) with Bax and Bad in colorectal cancer
-
Hattori T, Ookawa N, Fujita R, et al. Heterodimerization of Bcl-2 and Bcl-X(L) with Bax and Bad in colorectal cancer. Acta Oncol 2000; 39: 495-500.
-
(2000)
Acta Oncol
, vol.39
, pp. 495-500
-
-
Hattori, T.1
Ookawa, N.2
Fujita, R.3
-
32
-
-
16344389693
-
Connexin 26 correlates with Bcl-xL and Bax proteins expression in colorectal cancer
-
Kanczuga-Koda L, Sulkowski S, Koda M, et al. Connexin 26 correlates with Bcl-xL and Bax proteins expression in colorectal cancer. World J Gastroenterol 2005; 11: 1544-8.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 1544-1548
-
-
Kanczuga-Koda, L.1
Sulkowski, S.2
Koda, M.3
|