Deletion of UDP-glucose pyrophosphorylase reveals a UDP-glucose independent UDP-galactose salvage pathway in Leishmania major

Glycobiology

Volumn 20, Issue 7, 2010, Pages 872-882

  Lamerz, Anne Christin ^a,e   Damerow, Sebastian ^e   Kleczka, Barbara ^b,e   Wiese, Martin ^c,f   Van Zandbergen, Ger ^d,g   Lamerz, Jens ^h   Wenzel, Alexandear ^d,g   Hsu, Fong Fu ⁱ   Turk, John ⁱ   Beverley, Stephen M ^j   Routier, Françoise H ^a,e  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b ROCHE DIAGNOSTICS GMBH   (Germany)

^c HZM Pharmaservice   (Germany)

^d UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^e Inst of Med Microbiology/Hygiene   (Germany)

^f BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^g Institute of Medical Microbiology and Hygiene   (Germany)

^h F HOFFMANN LA ROCHE LTD   (Switzerland)

ⁱ Mass Spectrometry Resource Diabetes Metabolism and Lipid Research Department of Internal Medicine ^*  (Australia)

^j WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

more..

Author keywords

Nucleotide sugars metabolism; Trypanosomatids; UDP galactose; UDP glucose

Indexed keywords

GALACTOSE; GLUCOSE 1 PHOSPHATE; GLYCOINOSITOLPHOSPHOLIPID; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE GLUCOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; URIDINE DIPHOSPHATE GALACTOSE; URIDINE DIPHOSPHATE GLUCOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIUM; BIOSYNTHESIS; CATALYSIS; DELETION MUTANT; EPIMERIZATION; EUGLENOZOA; FEMALE; GAS LIQUID CHROMATOGRAPHY; GENE; GENE DELETION; GLYCOCALYX; HUMAN; HUMAN CELL; LEISHMANIA; LEISHMANIA MAJOR; MAMMAL; MOUSE; MUTANT; NONHUMAN; PARASITE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTOZOON; SURFACE PROPERTY; SYNTHESIS; VIRULENCE; AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; ENZYMOLOGY; GENETICS; MACROPHAGE; METABOLISM; MOLECULAR GENETICS; SIGNAL TRANSDUCTION;

LEISHMANIA MAJOR; PROTOZOA; TRYPANOSOMATIDAE;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; LEISHMANIA MAJOR; MACROPHAGES; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; SEQUENCE DELETION; SIGNAL TRANSDUCTION; URIDINE DIPHOSPHATE GALACTOSE; URIDINE DIPHOSPHATE GLUCOSE; UTP-GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE;

EID: 77956842229     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwq045     Document Type: Article

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