Anti-clastogenic effect of berberine against DMBA-induced clastogenesis

Basic and Clinical Pharmacology and Toxicology

Volumn 107, Issue 4, 2010, Pages 818-824

  Sindhu, Ganapathy ^a   Manoharan, Shanmugam ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BERBERINE; DIMETHYLBENZ[A]ANTHRACENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; BONE MARROW CELL; CELL STRESS; CHROMOSOME ABERRATION; CONTROLLED STUDY; DETOXIFICATION; DNA DAMAGE; DRUG EFFECT; ERYTHROCYTE; LIPID PEROXIDATION; NONHUMAN; OSTEOCLASTOGENESIS; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; SYRIAN HAMSTER;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ADMINISTRATION, ORAL; ANIMALS; ANTIMUTAGENIC AGENTS; ANTIOXIDANTS; BERBERINE; BONE MARROW CELLS; CHROMOSOME ABERRATIONS; COMET ASSAY; CRICETINAE; LIPID PEROXIDATION; MALE; MESOCRICETUS; MICRONUCLEUS TESTS; OXIDATIVE STRESS;

CRICETINAE; MESOCRICETUS AURATUS;

EID: 77956819896     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2010.00579.x     Document Type: Article

References (47)

1. Shimada T, Sugie A, Yamada H, Kawazoe H, Hashimoto M, Azuma E et al. Dose-response studies on the induction of liver cytochrome P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons in arylhydrocarbon responsive C57 BL6J mice. Xenobiotica 2003 33 : 957 71. (Pubitemid 37255405)
2. Baer - Dubowska W, Morris RJ, Gill RD, DiGiovanni J. Distribution of covalent DNA adducts in mouse epidermal subpopulations after topical application of benzo(a) pyrene and 7,12-dimethylbenz(a)anthracene. Cancer Res 1990 50 : 3048 54.
3. Odin AP. Vitamins as antimutagens: advantages and some possible mechanisms of antimutagenic action. Mutat Res 1997 386 : 39 67.
4. Ferguson LR. Antimutagens as cancer chemopreventive agents in the diet. Mutat Re 1994 307 : 395 410.
5. Guerin MR. Energy sources of polycyclic aromatic hydrocarbons. In : Gelboin HV, Tso POP (eds). Polycyclic Hydrocarbon and Cancer: Chemistry, Molecular Biology and Environment, Vol I. Academic Press
6. Gaizev AI, Sologub GR, Fomenko LA, Zaichkina SI, Kosyakova NI, Bradbury IJ. Effect of vitamin-antioxidant micronutrients on the frequency of spontaneous and in vitro gamma-ray induced micronuclei in lymphocytes of donors. The age factor 1996 17 : 493 9.
7. Hayashi M, Macgregor JT, Gatehouse DG, Adler ID, Blakey DH, Dertinger SD et al. In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol designing including repeated treatments, integration with toxicity testing and automated scoring. Environ Mol Mutagen 2000 35 : 234 52.
8. Hagmar H, Stromberg U, Tinnerbeeg H, Mikoczy Z. The usefulness of cytogenetic biomarkers as intermediate end points in carcinogenesis. Intl J Hyg Environ Health 2001 204 : 43 7.
9. Perez-Rivera AA, Hu T, Aardema MJ, Nash JF. Evaluation of the genotoxicity of the imidazole antifungal climbazole: comparison to published results for other azole compounds. Mutat Res 2009 672 : 27 39.
10. Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H et al. Single cell gelcomet Assay: Guidelines for In vitro and invivo genetic toxicology testing. Environ Mol Mutagen 2000 35 : 206 21.
11. Ribeiro DA, Scolastici C, Alves de Lima PL, Alencar Marques ME, Favero salvadori DM, Botucatu SP. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005 99 : 637 40.
12. Choi EJ. Antioxidative effects of hesperetin against 7,12-dimethylbenz(a) anthracene-induced oxidative stress in mice. Life Sciences 2008 82 : 1059 64.
13. 450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furano-coumarins on skin tumour initiation. Chem Res Toxicol 2002 15 : 226 35.
14. Farah MA, Ateeq B, Ahmad W. Antimutagenic effect of Neem leaves extract in freshwater fish, Channa punctatus evaluated by cytogenetic tests. Sci Tot Env 2006 364 : 200 14.
15. Hwang YP, Han EH, Choi JH, Kim HG, Lee KJ, Jeong TC et al. Chemopreventive effects of Furan-2-yl-3-pyridin-2-yl-propenone against 7,12-dimethylbenz[a]anthracene-inducible genotoxicity. Toxicol Appl Pharmacol 2008 228 : 343 50.
16. Frenkel K, Grunberger D, Kasai H, Komura H, Nakanishi K. Identification of novel 7,12-dimethylbenz(a)anthracene adducts in cellular ribonucleic acid. Biochemistry 1981 20 : 4377 81.
17. Frenkel K. The role of active oxygen species in biological damage and the effect of some chemopreventive agents. In : Troll W, Kennedy AR (eds). Protease Inhibitors as Cancer Chemopreventive Agents.
18. Halliwell B. Antioxidant characterization: methodology and mechanism. Biochem Pharm 1995 49 : 1341 8.
19. Zhou H, Mineshita S. The effect of Berberine chloride on experimental colitis in Rats In vivo and In vitro. J Pharm Exp Ther 2000 294 : 822 9.
20. Szaefer H, Krajka-kuzniak V, Baer-Dubowska W. The effect of initiating doses of benzo(a)pyrene and 7,12-dimethylbenz[a]anthracene on the expression of PAH activating enzymes and its modulation by plant phenols. Toxicol 2008 251 : 28 34.
21. Wu XJ, Lu WQ, Mersch-sundermann V. Benzo(a)pyrene induced micronucleus formation was modulated by persistant organic pollutants(POPs) in metabolically competent human HepG2 cells. Toxicol Lett 2003 144 : 143 50.
22. Fukuda K, Hibiya Y, Mutoh M, Koshiji M, Akao S, Fujiwara H. Inhibition by berberine of cyclooxygenase-2-transcriptional activity in human colon cancer cells. J Ethnopharm 1999 66 : 227 33.
23. Iwasa K, Lee DU, Kang SI, Wieg rebe W. Antimicrobial activity of 8-alkyl and 8-phenyl-substituted berberines and their 12-bromo-derivatives. J Nat Proc 1998 61 : 1150 3.
24. Lee YS, Kim WS, Kim KH, Yoon MJ, Cho HJ, Shen Y et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 2006 55 : 2256 64.
25. Jagetia GC, Nayak V, Vidyasagar MS. Evaluation of the antineoplastic activity of Tinospora cordifolia in cultured He La Cells. Cancer Lett 1998 127 : 71 82.
26. Abraham SK, Singh SP. Anti-genotoxicity and Glutathione S-transferase Activity in Mice Pretreated with Caffeinated and Decaffeinated Coffee. Food and Chemical Toxicology 1999 37 : 733 9.
27. Kilian DJ, Moreland FM, Benge MC, Legator MS, Whorton EB. A collaborative study to measure inter-laboratory variation with the in vivo bone marrow metaphase procedure. In : Kilbey BJ, Legator M, Nichols W, Romel C (eds Handbook of Mutagenicity Test Procedures. Elsevier
28. Gulkac MD, Akpinar G, Ustun H, Kanli AO. Effects of vitamin A on doxorubicin-induced chromosomal aberrations in bone marrow cells of rats. Mutagenesis 2004 19 : 231 6.
29. Schmid W. The micronucleus test. Mutat Res 1975 31 : 9 15.
30. Abraham SK, Paul J. Protective effects of lactic acid bacteria against genotoxicity in mice. Curr Sci 2001 80 : 1310 2.
31. El Ramy R, Ould Elhkim M, Lezmi S, Poul JM. Evaluation of the genotoxic potential of 3-monochloropropane-1,2-diol (3-MCPD) and its metabolites, glycidol and -chlorolactic acid, using the single cell gelcomet assay. Food and chemical toxicology 2007 45 : 41 8.
32. Yagi K. Lipid peroxides and human diseases. Chem Phys Lipids 1987 45 : 337 51.
33. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979 95 : 351 8.
34. Kakkar P, Das B, Viswanathan PN. A modified spectrophotometric assay of superoxide dismutase. Indian J. Biochem Biophys 1984 21 : 130 2.
35. Rotruck T, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG. Selenium: biochemical role as a component of glutathione peroxidase. Science 1973 179 : 588 590.
36. Sinha AK. Colorimetric assay of catalase. Anal Biochem 1972 47 : 389 94.
37. Beutler E, Kelley BM. The effect of sodium nitrite on RBC glutathione. Experientia 1963 29 : 96 7.
38. Omura T, Sato R. The carbon monoxide binding, pigment of liver. J Biol Chem 1964 239 : 2370.
39. Habig WH, Pabst MJ, Jakoby WB. Glutathione-S-transferase, the first enzymatic step in mercapturic acid formation. J Biol Chem 1974 249 : 7130 9.
40. Carlberg I, Mannervik B. Gluathione Reductase. Methods enzymol, Academic Press
41. Marcia DM, Kosinka W, Guttenplan JB. Mutagenesis induced by oral carcinogens in Lacz mouse (mutaTM mouse) tongue and other oral tissues. Carcinogenesis 1999 11 : 2167 70.
42. Muller K, Zucoloto S, AlbuquerqueJunior RF, Vannuchi H. Lack of inhibitory effect of Lycopene on dysplastic lesions induced by 7,12 dimethylbenz(a)anthracene in hamster buccal pouch. Nutr res 2007 27 : 574 9.
43. Baird WM, Hooven LA, Mahadevan B. Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action. Environ Mol Mutagen 2005 45 : 106 14.
44. Osaka M, Matsuo S, Koh T, Sugiyama T. Specific N-ras mutation in bone marrow within 48 H of 7,12-dimethylbenz[a] anthracene treatment in Huggins-Sugiyama rat leukemogenesis. Mol Carcinog 1998 16 : 126 31.
45. Grawish ME. Effects of Spirulina platensis extract on Syrian hamster cheek pouch mucosa painted with 7,12-dimethylbenz[a]anthracene. Oral oncol 2008 44 : 956 62.
46. Li H, Guo L, Jie S, Liu W, Zhu J, Du W et al. Berberine inhibits SDF - 1 induced AML cells leukemic stem cells migration via regulation of SDF - 1 level in bone marrow stromal cells. Biomedicine & Pharmacotherapy 2008 62 : 573 8.
47. Collins AR, Dobson VL, Dusinka M, Kennedy G, Stetina R. The comet assay: what can it really tell us? Mutat Res 1997 375 : 183 93.