Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells

Journal of Ethnopharmacology

Volumn 66, Issue 2, 1999, Pages 227-233

  Fukuda, Kazunori ^a   Hibiya, Yuko ^b   Mutoh, Michihiro ^b   Koshiji, Masatoshi ^a   Akao, Seigou ^a   Fujiwara, Hisayoshi ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NATIONAL CANCER CENTER   (Japan)

Author keywords

Berberine; Colon cancer; Cyclooxygenase 2; Transcriptional activity

Indexed keywords

ANTINEOPLASTIC ALKALOID; BERBERINE; CYCLOOXYGENASE 2; ISOQUINOLINE DERIVATIVE; PLANT EXTRACT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CHEMOPROPHYLAXIS; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; HERBAL MEDICINE; HUMAN; HUMAN CELL; PROTEIN SYNTHESIS; REPORTER GENE;

BERBERINE; CELL DIVISION; COLONIC NEOPLASMS; CYCLOHEXIMIDE; CYCLOOXYGENASE 2; GENES, REPORTER; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; PLASMIDS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN SYNTHESIS INHIBITORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0032985993     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(98)00162-7     Document Type: Article

References (20)

1. Chinery R., Beauchamp R.D., Shyr Y., Kirkland S.C., Coffey R.J., Morrow J.D. Antioxidants reduce cyclooxygenase-2 expression, prostaglandin production, and proliferation in colorectal cancer cells. Cancer Research. 58:1998;2323-2327.
2. Debnath D., Kumar G.S., Nandi R., Maiti M. Interaction of berberine chloride with deoxyribonucleic acids: evidence for base and sequence specificity. Indian Journal of Biochemistry and Biophysics. 26:1989;201-208.
3. DuBois R.N., Radhika A., Reddy B.S., Entingh A.J. Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors. Gastroenterology. 110:1996;1259-1262.
4. Higaki S., Nakamura M., Morohashi M., Hasegawa Y., Yamagishi T. Activity of eleven kampo formulations and eight kampo crude drugs against Propionibacterium acnes isolated from acne patients: retrospective evaluation in 1990 and 1995. Journal of Dermatology. 23:1996;871-875.
5. Ikram M. A review on the chemical and pharmacological aspects of genus Berberis. Planta Medica. 28:1975;353-358.
6. Ivanovska N., Philipov S. Study on the anti-inflammatory action of Berberis vulgaris root extract, alkaloid fractions and pure alkaloids. International Journal of Immunopharmacology. 18:1996;553-561.
7. Kimura M., Takatsuki A., Yamaguchi I. Blasticidin S deaminase gene from Aspergillus terreus (BSD): a new drug resistance gene for transfection of mammalian cells. Biochimica et Biophysica Acta. 1219:1994;653-659.
8. Kosaka T., Miyata A., Ihara H.et al. Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2. European Journal of Biochemistry. 221:1994;889-897.
9. Kuo C.L., Chou C.C., Yung B.Y.-M. Berberine complexes with DNA in the berberine-induced apoptosis in human leukemic HL-60 cells. Cancer Letters. 93:1995;193-200.
10. Lorand L., Campbell-Wilkes L.K., Cooperstein L. A filter paper assay for transamidating enzymes using radioactive amine substrates. Analytical Biochemistry. 50:1972;623-631.
11. Margis R., Borojevic R. Quantification of attached cells in tissue culture plates and on microcarriers. Analytical Biochemistry. 181:1989;209-211.
12. Nandi R., Debnath D., Maiti M. Interactions of berberine with poly(A) and tRNA. Biochimica et Biophysica Acta. 1049:1990;339-342.
13. Nishino H., Kitagawa K., Fujiki H., Iwashima A. Berberine sulfate inhibits tumor-promoting activity of teleocidin in two-stage carcinogenesis on mouse skin. Oncology. 43:1986;131-134.
14. Rabbani G.H., Butler T., Knight J., Sanyal S.C., Alam K. Randomized controlled trial of berberine sulfate therapy for diarrhea due to enterotoxigenic Escherichia coli and Vibrio cholerae. Journal of Infectious Diseases. 155:1987;979-984.
15. Schmeller T., Latz-Bruning B., Wink M. Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores. Phytochemistry. 44:1997;257-266.
16. Sheng H., Shao J., Kirkland S.C.et al. Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. Journal of Clinical Investigation. 99:1997;2254-2259.
17. Smalley W.E., DuBois R.N. Colorectal cancer and nonsteroidal anti-inflammatory drugs. Advances in Pharmacology. 39:1997;1-20.
18. Subbaramaiah K., Zakim D., Weksler B.B., Dannenberg A.J. Inhibition of cyclooxygenase: a novel approach to cancer prevention. Proceedings of the Society for Experimental Biology and Medicine. 216:1997;201-210.
19. Tsujii M., DuBois R.N. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell. 83:1995;493-501.
20. Vane J.R., Bakhle Y.S., Botting R.M. Cyclooxygenases 1 and 2. Annual Review of Pharmacology and Toxicology. 38:1998;97-120.