Specific N-ras mutation in bone marrow within 48 H of 7,12- dimethylbenz[a]anthracene treatment in Huggins-Sugiyama rat leukemogenesis

Molecular Carcinogenesis

Volumn 16, Issue 3, 1996, Pages 126-131

  Osaka, Mitsuhiko ^a   Matsuo, Shinji ^a   Koh, Takashi ^a   Sugiyama, Taketoshi ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b Shiga Medical Center   (Japan)

Author keywords

7,12 dimethylbenz a anthracene; leukemia; N ras mutation; rat

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; CONTROLLED STUDY; GENE AMPLIFICATION; GENE MAPPING; GENE MUTATION; GENETIC ANALYSIS; LEUKEMIA; LEUKEMOGENESIS; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; RAT;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; BASE SEQUENCE; BONE MARROW CELLS; DNA PRIMERS; DNA, NEOPLASM; GENES, RAS; LEUKEMIA, EXPERIMENTAL; MOLECULAR SEQUENCE DATA; POINT MUTATION; PRELEUKEMIA; RATS; TIME FACTORS;

ANIMALIA;

EID: 0029775118     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199607)16:3<126::AID-MC2>3.0.CO;2-F     Document Type: Article

References (30)

1. Huggins CB, Sugiyama T. Induction of leukemia in rat by pulse doses of 7, 12-dimethylbenz[a]anthracene. Proc Natl Acad Sci USA 55:74-81, 1966.
2. Sugiyama T, Kurita Y, Nishizuka Y. Chromosome abnormality in rat leukemia induced by 7, 12-dimethylbenz[a]anthracene. Science 158:1058-1059, 1967.
3. Kurita Y, Sugiyama T, Nishizuka Y. Cytogenetic studies on rat leukemia induced by pulse doses of 7, 12-dimethylbenz[a]anthracene. Cancer Res 28:1738-1752, 1968
4. Sugiyama T, Uenaka H, Ueda N, Fukuhara AS, Maeda S. Reproducible chromosomal changes of polycyclic hydrocarbon-induced rat leukemia: Incidence and chromosome banding pattern. J Natl Cancer Inst 60:153-160, 1978.
5. de Stoppelaar JM, Suijkerbuijk RF, van Kranen HJ, Faessen P, Mohn GR, Hoebee B. Chromosomal localization of the rat N-ras protooncogene by fluorescence in situ hybridization. Cytogenet Cell Genet 67:23-26, 1994.
6. Osaka M, Matsuo S, Koh T, et al. N-ras mutation in 7, 12-dimethylbenz[a]anthracene (DMBA)-induced erythroleukemia in Long-Evans rats. Cancer Lett 91:25-31, 1995
7. Sugiyama T. Specific vulnerability of the largest telocentric chromosome of rat bone marrow cells to 7, 12-dimethylbenz[a]anthracene. J Natl Cancer Inst 47:1267-1275, 1971.
8. Sugiyama T, Ueda N, Maeda S, et al. Chemical carcinogenesis in the rat: Common mode of action of carcinogens at the chromosome level. J Natl Cancer Inst 67:831-839, 1981.
9. Takeda S, Ichii S, Nakamura Y. Detection of K-ras mutation in sputum by mutant-allele-specific amplification (MASA). Hum Mutat 2:112-117, 1993.
10. Schurr PE. Composition and preparation of experimental intravenous fat emulsions. Cancer Res 29:258-260, 1969.
11. van Kranen HJ, van Steeg H, Schoren L, et al. The rat N-ras gene; interference of pseudogenes with the detection of activating point mutations. Carcinogenesis 15:307-311, 1994.
12. Maeda S, Uenaka H, Ueda N, Shiraishi N, Sugiyama T. Establishment and chromosome studies of in vitro lines of chemically induced rat erythroblastic leukemia cells. J Natl Cancer Inst 64:539-546, 1980.
13. Zarbl H, Sukumar S, Arthur AV, Martin-Zanca D, Barbacid M. Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N methylurea during initiation of mammary carcinogenesis in rats. Nature 315:382-385, 1985.
14. Bizub D, Wood AW, Skalka AM. Mutagenesis of the Ha-ras oncogene in mouse skin tumors induced by polycyclic aromatic hydrocarbons. Proc Natl Acad Sci USA 83:6048-6052, 1986.
15. Quintanilla M, Brown K, Ramsden M, Balmain A. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature 322:78-80, 1986.
16. Balmain A, Brown K. Oncogene activation in chemical carcinogenesis. Adv Cancer Res 51:147-182, 1988.
17. Kumar R, Medina D, Sukumar S. Activation of Ha-ras oncogenes in preneoplastic mouse mammary tissues. Oncogene 5:1271-1277, 1990.
18. Nakazawa H, Aguelon AM, Yamasaki H. Relationship between chemical induced Ha-ras mutation and transformation of BALB/c 3T3 cells: Evidence for chemical-specific activation and cell type-specific recruitment of oncogene in transformation. Mol Carcinog 3:202-209, 1990.
19. Nakazawa H, Aguelon AM, Yamasaki H. Identification and quantification of a carcinogen-induced molecular initiation event in cell transformation. Oncogene 7:2295-2301, 1992.
20. Balmain A, Ramsden M, Bowden GT, Smith J. Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas. Nature 307:658-660, 1984.
21. Reynolds SH, Stowers SJ, Maronpot RR, Anderson MW, Aaronson SA. Detection and identification of activated oncogenes in spontaneously occurring benign and malignant hepatocellular tumors of the B6C3F1 mouse. Proc Natl Acad Sci USA 83:33-37, 1986.
22. Buchmann A, Mahr J, Baur-Hofmann R, Schwarz M. Mutations at codon 61 of the Ha-ras proto-oncogene in precancerous liver lesions of the B6C3F1 mouse. Mol Carcinog 2:121-125, 1989.
23. Cerny WL, Mangold KA, Scarpelli DG. K-ras mutation is an early event in pancreatic duct carcinogenesis in the syrian golden hamster. Cancer Res 52:4507-4513, 1992.
24. Vivona AA, Shpitz B, Medline A, et al. K-ras mutation in aberrant crypt foci, adenomas and adenocarcinoma during azoxymethane-induced colon carcinogenesis. Carcinogenesis 14:1777-1781, 1993.
25. Newcomb EW, Bayona W, Pishardy S. N-methylnitrosourea-induced Ki-ras codon 12 mutations: Early events in mouse thymic lymphomas. Mol Carcinog 13:89-95, 1995.
26. Kumar R, Sukumar S, Barbacid M, Activation of ras oncogenes preceding the onset of neoplasia. Science 248:1101-1104, 1990.
27. Kwong YY, Husain Z, Biswas DK. c-Ha-ras gene mutation and activation precede pathological changes in DMBA-induced in vivo carcinogenesis. Oncogene 7:1481-1489, 1992.
28. Radich JP, Kopecky KJ, Appelbaum F, Willman CL, Collins SJ. N-ras mutations in acute myelogenous leukemia: A review of the current literature and an update of the Southwest Oncology Group Experience. Leuk Lymphoma 6:325-334, 1992.
29. Loktionov A, Hollstein M, Martel N, et al. Tissue-specific activating mutations of Ha- and Ki-ras oncogenes in skin, lung, and liver tumors induced in mice following transplacental exposure to DMBA. Mol Carcinog 3:134-140, 1990.
30. Guerrero I, Villasante A, Corces V, Pellicer A. Loss of the normal N-ras allele in a mouse thymic lymphoma induced by a chemical carcinogen. Proc Natl Acad Sci USA 82:7810-7814, 1985.