메뉴 건너뛰기




Volumn 27, Issue SUPPL. 1, 2006, Pages

The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis

Author keywords

Immunomodulatory therapy; Multiple sclerosis; Neuroprotection; Neurotrophic factors

Indexed keywords

APOPTOSIS INHIBITOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCIUM CHANNEL BLOCKING AGENT; CILIARY NEUROTROPHIC FACTOR; CYCLOSPORIN; GABAERGIC RECEPTOR AFFECTING AGENT; GLATIRAMER; IMMUNOMODULATING AGENT; IMMUNOSUPPRESSIVE AGENT; LEUKEMIA INHIBITORY FACTOR; MINOCYCLINE; MYELIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEURITE PROMOTING FACTOR; NEUROPROTECTIVE AGENT; NEUROTROPHIC FACTOR; RAPAMYCIN; RILUZOLE; SCAVENGER; SODIUM CHANNEL BLOCKING AGENT; TACROLIMUS;

EID: 33646791175     PISSN: 15901874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10072-006-0537-7     Document Type: Article
Times cited : (72)

References (35)
  • 1
    • 0037369638 scopus 로고    scopus 로고
    • Neurotrophic cross-talk between the nervous and immune systems: Implications for neurological diseases
    • Kerschensteiner M, Stadelmann C, Dechant G et al (2003) Neurotrophic cross-talk between the nervous and immune systems: Implications for neurological diseases. Ann Neurol 53:292-304
    • (2003) Ann Neurol , vol.53 , pp. 292-304
    • Kerschensteiner, M.1    Stadelmann, C.2    Dechant, G.3
  • 2
    • 0034710340 scopus 로고    scopus 로고
    • The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis
    • Hohlfeld R, Kerschensteiner M, Stadelmann C et al (2000) The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis. J Neuroimmunol 107:161-166
    • (2000) J Neuroimmunol , vol.107 , pp. 161-166
    • Hohlfeld, R.1    Kerschensteiner, M.2    Stadelmann, C.3
  • 3
    • 0033049143 scopus 로고    scopus 로고
    • Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy
    • Moalem G, Leibowitz-Amit R, Yoles E et al (1999) Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy. Nature Med 5:49-55
    • (1999) Nature Med , vol.5 , pp. 49-55
    • Moalem, G.1    Leibowitz-Amit, R.2    Yoles, E.3
  • 4
    • 0033168727 scopus 로고    scopus 로고
    • Innate and adaptive immune responses can be beneficial for CNS repair
    • Schwartz M, Moalem G, Leibowitz-Amit R, Cohen IR (1999) Innate and adaptive immune responses can be beneficial for CNS repair. Trends Neurosci 22:295-299
    • (1999) Trends Neurosci , vol.22 , pp. 295-299
    • Schwartz, M.1    Moalem, G.2    Leibowitz-Amit, R.3    Cohen, I.R.4
  • 5
    • 0029898913 scopus 로고    scopus 로고
    • Nerve growth factor is an autocrine survival factor for memory B lymphocytes
    • Torcia M, Bracci-Laudiero L, Lucibello M et al (1996) Nerve growth factor is an autocrine survival factor for memory B lymphocytes. Cell 85:345-356
    • (1996) Cell , vol.85 , pp. 345-356
    • Torcia, M.1    Bracci-Laudiero, L.2    Lucibello, M.3
  • 6
    • 0033103608 scopus 로고    scopus 로고
    • Activated human T cells, B cells and monocytes produce brain-derived neurotrophic factor (BDNF) in vitro and in brain lesions: A neuroprotective role of inflammation?
    • Kerschensteiner M, Gallmeier E, Behrens L et al (1999) Activated human T cells, B cells and monocytes produce brain-derived neurotrophic factor (BDNF) in vitro and in brain lesions: A neuroprotective role of inflammation? J Exp Med 189:865-870
    • (1999) J Exp Med , vol.189 , pp. 865-870
    • Kerschensteiner, M.1    Gallmeier, E.2    Behrens, L.3
  • 7
    • 0033152935 scopus 로고    scopus 로고
    • Clonally restricted production of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3 mRNA by human immune cells and Th1/Th2-polarized expression of their receptors
    • Besser M, Wank R (1999) Clonally restricted production of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3 mRNA by human immune cells and Th1/Th2-polarized expression of their receptors. J Immunol 162:6303-6306
    • (1999) J Immunol , vol.162 , pp. 6303-6306
    • Besser, M.1    Wank, R.2
  • 8
    • 0029892470 scopus 로고    scopus 로고
    • Physiology of the neurotrophins
    • Lewin GR, Barde YA (1996) Physiology of the neurotrophins. Annu Rev Neurosci 19:289-317
    • (1996) Annu Rev Neurosci , vol.19 , pp. 289-317
    • Lewin, G.R.1    Barde, Y.A.2
  • 9
    • 0026439389 scopus 로고
    • The cognitive paradigm and the immunological homunculus
    • Cohen IR (1992) The cognitive paradigm and the immunological homunculus. Immunol Today 13:490-494
    • (1992) Immunol Today , vol.13 , pp. 490-494
    • Cohen, I.R.1
  • 10
    • 0036281689 scopus 로고    scopus 로고
    • CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation
    • Linker RA, Mäurer M, Gaupp S et al (2002) CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation. Nature Med 8:620-624
    • (2002) Nature Med , vol.8 , pp. 620-624
    • Linker, R.A.1    Mäurer, M.2    Gaupp, S.3
  • 11
    • 0036284982 scopus 로고    scopus 로고
    • LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival
    • Butzkueven H, Zhang J-G, Soilu-Hänninen M et al (2002) LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival. Nature Med 8:613-619
    • (2002) Nature Med , vol.8 , pp. 613-619
    • Butzkueven, H.1    Zhang, J.-G.2    Soilu-Hänninen, M.3
  • 12
    • 0036191226 scopus 로고    scopus 로고
    • Association of a null mutation in the CNTF gene with early onset of multiple sclerosis
    • Giess R, Maurer M, Linker R et al (2002) Association of a null mutation in the CNTF gene with early onset of multiple sclerosis. Arch Neurol 59:407-409
    • (2002) Arch Neurol , vol.59 , pp. 407-409
    • Giess, R.1    Maurer, M.2    Linker, R.3
  • 13
    • 0032576752 scopus 로고    scopus 로고
    • Axonal transection in the lesion of multiple sclerosis
    • Trapp BD, Peterson J, Ransohoff RM et al (1998) Axonal transection in the lesion of multiple sclerosis. N Engl J Med 338:278-285
    • (1998) N Engl J Med , vol.338 , pp. 278-285
    • Trapp, B.D.1    Peterson, J.2    Ransohoff, R.M.3
  • 14
    • 0031002545 scopus 로고    scopus 로고
    • Axonal damage in acute multiple sclerosis lesions
    • Ferguson B, Matyszak MK, Esiri MM, Perry VH (1997) Axonal damage in acute multiple sclerosis lesions. Brain 120:393-399
    • (1997) Brain , vol.120 , pp. 393-399
    • Ferguson, B.1    Matyszak, M.K.2    Esiri, M.M.3    Perry, V.H.4
  • 15
    • 0032887020 scopus 로고    scopus 로고
    • Axonal pathology in multiple sclerosis. A historical note
    • Kornek B, Lassmann H (1999) Axonal pathology in multiple sclerosis. A historical note. Brain Pathol 9:651-656
    • (1999) Brain Pathol , vol.9 , pp. 651-656
    • Kornek, B.1    Lassmann, H.2
  • 16
    • 0036602982 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases
    • Neumann H, Medana IM, Bauer J, Lassmann H (2002) Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases. Trends Neurosci 25:313-319
    • (2002) Trends Neurosci , vol.25 , pp. 313-319
    • Neumann, H.1    Medana, I.M.2    Bauer, J.3    Lassmann, H.4
  • 17
    • 0034618094 scopus 로고    scopus 로고
    • Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
    • Babbe H, Roers A, Waisman A et al (2000) Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J Exp Med 192:393-404
    • (2000) J Exp Med , vol.192 , pp. 393-404
    • Babbe, H.1    Roers, A.2    Waisman, A.3
  • 18
    • 1442354894 scopus 로고    scopus 로고
    • + T cells persist as clonal expansions in the cerebrospinal fluid and blood
    • + T cells persist as clonal expansions in the cerebrospinal fluid and blood. Proc Natl Acad Sci USA 101:2428-2433
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2428-2433
    • Skulina, C.1    Schmidt, S.2    Dornmair, K.3
  • 19
    • 0036191549 scopus 로고    scopus 로고
    • Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patients
    • Jacobsen M, Cepok S, Quak E et al (2002) Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patients. Brain 125:538-550
    • (2002) Brain , vol.125 , pp. 538-550
    • Jacobsen, M.1    Cepok, S.2    Quak, E.3
  • 20
    • 0037678717 scopus 로고    scopus 로고
    • Axonal injury in multiple sclerosis
    • Lassmann H (2003) Axonal injury in multiple sclerosis. J Neurol Neurosurg Psych 74:695-697
    • (2003) J Neurol Neurosurg Psych , vol.74 , pp. 695-697
    • Lassmann, H.1
  • 21
    • 0013292906 scopus 로고    scopus 로고
    • The role of nitric oxide in multiple sclerosis
    • Smith KJ, Lassmann H (2002) The role of nitric oxide in multiple sclerosis. Lancet Neurology 1:232-241
    • (2002) Lancet Neurology , vol.1 , pp. 232-241
    • Smith, K.J.1    Lassmann, H.2
  • 22
    • 0037226838 scopus 로고    scopus 로고
    • Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases
    • Aboul-Enein F, Rauschka H, Kornek B et al (2003) Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases. J Neuropathol Exp Neurol 62:25-33
    • (2003) J Neuropathol Exp Neurol , vol.62 , pp. 25-33
    • Aboul-Enein, F.1    Rauschka, H.2    Kornek, B.3
  • 23
    • 0036845819 scopus 로고    scopus 로고
    • Glatiramer acetate-specific T-helper 1-and 2-type cell lines produce BDNF: Implications for multiple sclerosis therapy
    • Ziemssen T, Kumpfel T, Klinkert WEF et al (2002) Glatiramer acetate-specific T-helper 1-and 2-type cell lines produce BDNF: implications for multiple sclerosis therapy. Brain 125:2381-2391
    • (2002) Brain , vol.125 , pp. 2381-2391
    • Ziemssen, T.1    Kumpfel, T.2    Klinkert, W.E.F.3
  • 24
    • 1842845857 scopus 로고    scopus 로고
    • The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: A pilot study
    • Kalkers NF, Barkhof F, Bergers E et al (2002) The effect of the neuroprotective agent riluzole on MRI parameters in primary progressive multiple sclerosis: A pilot study. Mult Scler 8:532-533
    • (2002) Mult Scler , vol.8 , pp. 532-533
    • Kalkers, N.F.1    Barkhof, F.2    Bergers, E.3
  • 25
    • 0034961705 scopus 로고    scopus 로고
    • Neuroimmunophilins: Novel neuroprotective and neuroregenerative targets
    • Guo X, Dillman JF, III, Dawson VL, Dawson TM (2001) Neuroimmunophilins: novel neuroprotective and neuroregenerative targets. Ann Neurol 50:6-16
    • (2001) Ann Neurol , vol.50 , pp. 6-16
    • Guo, X.1    Dillman III, J.F.2    Dawson, V.L.3    Dawson, T.M.4
  • 26
    • 0141818987 scopus 로고    scopus 로고
    • Immunophilins in nervous system degeneration and regeneration
    • Avramut M, Achim CL (2003) Immunophilins in nervous system degeneration and regeneration. Curr Top Med Chem 3:1376-1382
    • (2003) Curr Top Med Chem , vol.3 , pp. 1376-1382
    • Avramut, M.1    Achim, C.L.2
  • 27
    • 0036260089 scopus 로고    scopus 로고
    • Targeting leukocyte MMPs and transmigration: Minocycline as a potential therapy for multiple sclerosis
    • Brundula V, Rewcastle NB, Metz LM et al (2002) Targeting leukocyte MMPs and transmigration: Minocycline as a potential therapy for multiple sclerosis. Brain 125:1297-1308
    • (2002) Brain , vol.125 , pp. 1297-1308
    • Brundula, V.1    Rewcastle, N.B.2    Metz, L.M.3
  • 28
    • 0036157268 scopus 로고    scopus 로고
    • Inhibition of autoimmune encephalomyelitis by a tetracycline
    • Popovic N, Schubart A, Goetz BD et al (2002) Inhibition of autoimmune encephalomyelitis by a tetracycline. Ann Neurol 51:215-223
    • (2002) Ann Neurol , vol.51 , pp. 215-223
    • Popovic, N.1    Schubart, A.2    Goetz, B.D.3
  • 29
    • 0033485704 scopus 로고    scopus 로고
    • Clinical trials with neuroprotective drugs in acute ischaemic stroke: Are we doing the right thing?
    • De Keyser J, Sulter G, Luiten PG (1999) Clinical trials with neuroprotective drugs in acute ischaemic stroke: Are we doing the right thing? Trends Neurosci 22:535-540
    • (1999) Trends Neurosci , vol.22 , pp. 535-540
    • De Keyser, J.1    Sulter, G.2    Luiten, P.G.3
  • 30
    • 0030989875 scopus 로고    scopus 로고
    • Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives
    • Hohlfeld R (1997) Biotechnological agents for the immunotherapy of multiple sclerosis. Principles, problems and perspectives. Brain 120:865-916
    • (1997) Brain , vol.120 , pp. 865-916
    • Hohlfeld, R.1
  • 31
    • 0032794046 scopus 로고    scopus 로고
    • Treatment of multiple sclerosis: Recent trial and future perspectives
    • Noseworthy JH, Gold R, Hartung HP (1999) Treatment of multiple sclerosis: Recent trial and future perspectives. Curr Opin Neurol 12:279-293
    • (1999) Curr Opin Neurol , vol.12 , pp. 279-293
    • Noseworthy, J.H.1    Gold, R.2    Hartung, H.P.3
  • 32
    • 0036546066 scopus 로고    scopus 로고
    • New concepts in the immunopathogenesis of multiple sclerosis
    • Hemmer B, Archelos JJ, Hartung HP (2002) New concepts in the immunopathogenesis of multiple sclerosis. Nature Rev Neurosci 3:291-301
    • (2002) Nature Rev Neurosci , vol.3 , pp. 291-301
    • Hemmer, B.1    Archelos, J.J.2    Hartung, H.P.3
  • 33
    • 18744436601 scopus 로고    scopus 로고
    • Encephalitogenic potential of myelin basic protein-specific T cells isolated from normal rhesus macaques
    • Meinl E, Hoch RM, Dornmair K et al (1997) Encephalitogenic potential of myelin basic protein-specific T cells isolated from normal rhesus macaques. Am J Pathol 150:445-453
    • (1997) Am J Pathol , vol.150 , pp. 445-453
    • Meinl, E.1    Hoch, R.M.2    Dornmair, K.3
  • 34
    • 0028866451 scopus 로고
    • Gene transfer through the blood-nerve barrier: Nerve growth factor engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis
    • Kramer R, Zhang Y, Gehrmann J et al (1995) Gene transfer through the blood-nerve barrier: Nerve growth factor engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis. Nature Med 1:1162-1166
    • (1995) Nature Med , vol.1 , pp. 1162-1166
    • Kramer, R.1    Zhang, Y.2    Gehrmann, J.3
  • 35
    • 0344780200 scopus 로고    scopus 로고
    • + T lymphocytes: Green fluorescent protein engineered, encephalitogenic T cells used to illuminate immune responses in the brain
    • + T lymphocytes: Green fluorescent protein engineered, encephalitogenic T cells used to illuminate immune responses in the brain. Nature Med 5:843-847
    • (1999) Nature Med , vol.5 , pp. 843-847
    • Flügel, A.1    Willem, M.2    Berkowicz, T.3    Wekerle, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.