1,2-Dilinoleoyl-sn-glycero-3-phosphoethanolamine ameliorates age-related spatial memory deterioration by preventing neuronal cell death

Behavioral and Brain Functions

Volumn 6, Issue , 2010, Pages

  Yaguchi, Takahiro ^a   Nagata, Tetsu ^a   Nishizaki, Tomoyuki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DILINOLEOYL SN GLYCERO 3 PHOSPHOETHANOLAMINE; AMYLOID BETA PROTEIN[1-40]; MACROGOL; PHOSPHOETHANOLAMINE; THAPSIGARGIN; UNCLASSIFIED DRUG; 1,2 DILINOLEOYL 3 PHOSPHATIDYLETHANOLAMINE; 1,2-DILINOLEOYL-3-PHOSPHATIDYLETHANOLAMINE; AMYLOID BETA PROTEIN; PEPTIDE FRAGMENT; PHOSPHATIDYLETHANOLAMINE;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BEHAVIOR; CELL VIABILITY; COGNITIVE DEFECT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HIPPOCAMPUS; MALE; MEMORY DISORDER; MOTOR ACTIVITY; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY; AGE; ANIMAL; CELL DEATH; CELL STRAIN; CELL SURVIVAL; DISEASE MODEL; DRUG ADMINISTRATION; DRUG EFFECT; MOUSE STRAIN; NERVE CELL; PATHOLOGY;

AGE FACTORS; AMYLOID BETA-PEPTIDES; ANIMALS; CELL DEATH; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; HIPPOCAMPUS; MALE; MEMORY DISORDERS; MICE; MICE, INBRED STRAINS; NEURONS; PC12 CELLS; PEPTIDE FRAGMENTS; PHOSPHATIDYLETHANOLAMINES; RATS; THAPSIGARGIN;

EID: 77956492363     PISSN: 17449081     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-9081-6-52     Document Type: Article

References (44)

1. Hitomi J, Katayama T, Eguchi Y, Kudo T, Taniguchi M, Koyama Y, Manabe T, Yamagishi S, Bando Y, Imaizumi K, Tsujimoto Y, Tohyama M. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death. J Cell Biol 2004, 165:347-356. 10.1083/jcb.200310015, 2172196, 15123740.
2. Nakagawa T, Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 2000, 150:887-894. 10.1083/jcb.150.4.887, 2175271, 10953012.
3. Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β. Nature 2000, 403:98-103. 10.1038/47513, 10638761.
4. Imai Y, Soda M, Inoue H, Hattori N, Mizuno Y, Takahashi R. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 2000, 105:891-902.
5. Imai Y, Soda M, Takahashi R. Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J Biol Chem 2000, 275:35661-35664. 10.1074/jbc.C000447200, 10973942.
6. Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat Cell Biol 1999, 1:479-485. 10.1038/70265, 10587643.
7. Sato N, Imaizumi K, Manabe T, Taniguchi M, Hitomi J, Katayama T, Yoneda T, Morihara T, Yasuda Y, Takagi T, Kudo T, Tsuda T, Itoyama Y, Makifuchi T, Fraser PE, St George-Hyslop P, Tohyama M. Increased production of β-amyloid and vulnerability to endoplasmic reticulum stress by an aberrant spliced form of presenilin 2. J Biol Chem 2001, 276:2108-2114. 10.1074/jbc.M006886200, 11031265.
8. Tamatani M, Matsuyama T, Yamaguchi A, Mitsuda N, Tsukamoto Y, Taniguchi M, Che YH, Ozawa K, Hori O, Nishimura H, Yamashita A, Okabe M, Yanagi H, Stern DM, Ogawa S, Tohyama M. ORP150 protects against hypoxia/ischemia-induced neuronal death. Nat Med 2001, 7:317-323. 10.1038/85463, 11231630.
9. Wigley WC, Fabunmi RP, Lee MG, Marino CR, Muallem S, DeMartino GN, Thomas PJ. Dynamic association of proteasomal machinery with the centrosome. J Cell Biol 1999, 145:481-490. 10.1083/jcb.145.3.481, 2185077, 10225950.
10. Katsel P, Li C, Haroutunian V. Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: a shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?. Neurochem Res 2007, 32:845-856. 10.1007/s11064-007-9297-x, 17342407.
11. He X, Huang Y, Li B, Gong CX, Schuchman EH. Deregulation of sphingolipid metabolism in Alzheimer's disease. Neurobiol Aging 2010, 31:398-408. 10.1016/j.neurobiolaging.2008.05.010, 18547682.
12. Malaplate-Armand C, Florent-Béchard S, Youssef I, Koziel V, Sponne I, Kriem B, Leininger-Muller B, Olivier JL, Oster T, Pillot T. Soluble oligomers of amyloid-β peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway. Neurobiol Dis 2006, 23:178-189. 10.1016/j.nbd.2006.02.010, 16626961.
13. Arboleda G, Huang TJ, Waters C, Verkhratsky A, Fernyhough P, Gibson RM. Insulin-like growth factor-1-dependent maintenance of neuronal metabolism through the phosphatidylinositol 3-kinase-Akt pathway is inhibited by C2-ceramide in CAD cells. Eur J Neurosci 2007, 25:3030-3038. 10.1111/j.1460-9568.2007.05557.x, 17561816.
14. Arboleda G, Waters C, Gibson R. Inhibition of caspases but not of calpains temporarily protect against C2-ceramide-induced death of CAD cells. Neurosci Lett 2007, 421:245-249. 10.1016/j.neulet.2007.05.032, 17573191.
15. Farooqui AA, Horrocks LA, Farooqui T. Interactions between neural membrane glycerophospholipid and sphingolipid mediators: a recipe for neural cell survival or suicide. J Neurosci Res 2007, 85:1834-1850. 10.1002/jnr.21268, 17393491.
16. Yaguchi T, Nagata T, Nishizaki T. Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting α7 nicotinic ACh receptors. Life Sci 2009, 84:263-266. 10.1016/j.lfs.2008.12.003, 19100751.
17. Yaguchi T, Nagata T, Nishizaki T. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine improves cognitive decline by enhancing long-term depression. Behav Brain Res 2009, 204:129-132. 10.1016/j.bbr.2009.05.027, 19482045.
18. Nomura T, Nishizaki T, Enomoto T, Itoh H. A long-lasting facilitation of hippocampal neurotransmission via a phospholipase A2 signaling pathway. Life Sci 2001, 68:2885-2891. 10.1016/S0024-3205(01)01072-4, 11432454.
19. Ikeuchi Y, Nishizaki T, Matsuoka T, Sumikawa K. Arachidonic acid potentiates ACh receptor currents by protein kinase C activation but not by receptor phosphorylation. Biochem Biophys Res Commun 1996, 221:716-721. 10.1006/bbrc.1996.0662, 8630027.
20. Nishizaki T, Ikeuchi Y, Matsuoka T, Sumikawa K. Short-term depression and long-term enhancement of ACh-gated channel currents induced by linoleic and linolenic acid. Brain Res 1997, 751:253-258. 10.1016/S0006-8993(96)01405-9, 9099812.
21. Nishizaki T, Ikeuchi Y, Matsuoka T, Sumikawa K. Oleic acid enhances ACh receptor currents by activation of Ca2+/calmodulin-dependent protein kinase II. Neuroreport 1997, 8:597-601. 10.1097/00001756-199702100-00004, 9106730.
22. Nishizaki T, Matsuoka T, Nomura T, Sumikawa K. Modulation of ACh receptor currents by arachidonic acid. Mol Brain Res 1998, 57:173-179. 10.1016/S0169-328X(98)00091-6, 9630614.
23. Nishizaki T, Matsuoka T, Nomura T, Enikolopov G, Sumikawa K. Arachidonic acid potentiates currents through Ca2+-permeable AMPA receptors by interacting with a CaMKII pathway. Mol Brain Res 1999, 67:184-189. 10.1016/S0169-328X(99)00042-X, 10101246.
24. Nishizaki T, Nomura T, Matsuoka T, Enikolopov G, Sumikawa K. Arachidonic acid induces a long-lasting facilitation of hippocampal synaptic transmission by modulating PKC activity and nicotinic ACh receptors. Mol Brain Res 1999, 69:263-272. 10.1016/S0169-328X(99)00117-5, 10366747.
25. Yaguchi T, Yamamoto S, Nagata T, Kanno T, Tanaka A, Nishizaki T. Effects of cis-unsaturated free fatty acids on PKC-ε activation and nicotinic ACh receptor responses. Mol Brain Res 2005, 133:320-324. 10.1016/j.molbrainres.2004.10.031, 15710250.
26. Nishizaki T, Nomura T, Matsuoka T, Tsujishita Y. Arachidonic acid as a messenger for the expression of long-term potentiation. Biochem Biophys Res Commun 1999, 254:446-449. 10.1006/bbrc.1998.9961, 9918858.
27. Ikeuchi Y, Nishizaki T, Matsuoka T, Sumikawa K. Long-lasting enhancement of ACh receptor currents by lysophospholipids. Mol Brain Res 1997, 45:317-320. 10.1016/S0169-328X(96)00292-6, 9149106.
28. Nishizaki T, Sumikawa K. Lysophosphatidic acid potentiates ACh receptor currents by G-protein-mediated activation of protein kinase C. Mol Brain Res 1997, 50:121-126. 10.1016/S0169-328X(97)00177-0, 9406926.
29. Kanno T, Yamamoto H, Yaguchi T, Hi R, Mukasa T, Fujikawa H, Nagata T, Yamamoto S, Tanaka A, Nishizaki T. The linoleic acid derivative DCP-LA selectively activates PKC-ε, possibly binding to the phosphatidylserine binding site. J Lipid Res 2006, 47:1146-1156. 10.1194/jlr.M500329-JLR200, 16520488.
30. Tanaka A, Nishizaki T. The newly synthesized linoleic acid derivative FR236924 induces a long-lasting facilitation of hippocampal neurotransmission by targeting nicotinic acetylcholine receptors. Bioorg Med Chem Lett 2003, 13:1037-1040. 10.1016/S0960-894X(03)00089-1, 12643906.
31. Yamamoto S, Kanno T, Nagata T, Yaguchi T, Tanaka A, Nishizaki T. The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic α7 acetylcholine receptors on the glutamatergic terminals. Neuroscience 2005, 130:207-213. 10.1016/j.neuroscience.2004.09.016, 15561436.
32. Nagata T, Yamamoto S, Yaguchi T, Iso H, Tanaka A, Nishizaki T. The newly synthesized linoleic acid derivative DCP-LA ameliorates memory deficits in animal models treated with amyloid-β peptide and scopolamine. Psychogeriatrics 2005, 5:122-126.
33. Nagata T, Tomiyama T, Mori H, Yaguchi T, Nishizaki T. DCP-LA neutralizes mutant amyloid β peptide-induced impairment of long-term potentiation and spatial learning. Behav Brain Res 2010, 206:151-154. 10.1016/j.bbr.2009.08.032, 19716848.
34. Yaguchi T, Fujikawa H, Nishizaki T. Linoleic acid derivative DCP-LA protects neurons from oxidative stress-induced apoptosis by inhibiting caspase-3/-9 activation. Neurochem Res 2010, 35:712-717. 10.1007/s11064-010-0124-4, 20099079.
35. Yaguchi T, Nagata T, Mukasa T, Fujikawa H, Yamamoto H, Yamamoto S, Iso H, Tanaka A, Nishizaki T. Linoleic acid derivative DCP-LA improves learning impairment in SAMP8. NeuroReport 2006, 17:105-108. 10.1097/01.wnr.0000194388.12408.0a, 16361960.
36. Markowska AL, Spangler EL, Ingram DK. Behavioral assessment of the senescence-accelerated mouse (SAMP8 and R1). Physiol Behav 1998, 64:15-26. 10.1016/S0031-9384(98)00011-0, 9661977.
37. Takeda T, Hosokawa M, Higuchi K. Senescence-accelerated mouse (SAM): a novel murine model of accelerated senescence. J Am Geriatr Soc 1991, 39:911-919.
38. Maurice T, Roman FJ, Su TP, Privat A. Beneficial effects of sigma agonists on the age-related learning impairment in the senescence-accelerated mouse (SAM). Brain Res 1996, 733:219-230. 10.1016/0006-8993(96)00565-3, 8891305.
39. Nitta A, Naruhashi K, Umemura M, Hasegawa T, Furukawa S, Sekiguchi F, Ishibashi K, Nabeshima T. Age-related changes in learning and memory and cholinergic neuronal function in senescence accelerated mice (SAM). Behav Brain Res 1995, 72:49-55. 10.1016/0166-4328(96)00040-X, 8788856.
40. Strong R, Reddy V, Morley JE. Cholinergic deficits in the septal-hippocampal pathway of the SAM-P/8 senescence accelerated mouse. Brain Res 2003, 966:150-156. 10.1016/S0006-8993(02)04192-6, 12646318.
41. Yasuda Y, Saito M, Yamamura T, Yaguchi T, Nishizaki T. Extracellular adenosine induces apoptosis in Caco-2 human colonic cancer cells by activating caspase-9/-3 via A2a adenosine receptors. J Gastroenterol 2009, 44:56-65. 10.1007/s00535-008-2273-7, 19159073.
42. Costa RO, Ferreiro E, Cardoso SM, Oliveira CR, Pereira CM. ER stress-mediated apoptotic pathway induced by Aβ peptide requires the presence of functional mitochondria. J Alzheimers Dis 2010, 20:625-636.
43. Yoshida I, Monji A, Tashiro K, Nakamura K, Inoue R, Kanba S. Depletion of intracellular Ca2+ store itself may be a major factor in thapsigargin-induced ER stress and apoptosis in PC-12 cells. Neurochem Int 2006, 48:696-702. 10.1016/j.neuint.2005.12.012, 16481070.
44. Brandewiede J, Schachner M, Morellini F. Ethological analysis of the senescence-accelerated P/8 mouse. Behav Brain Res 2005, 158:109-121. 10.1016/j.bbr.2004.08.012, 15680199.