Short-term depression and long-term enhancement of ACh-gated channel currents induced by linoleic and linolenic acid

Brain Research

Volumn 751, Issue 2, 1997, Pages 253-258

  Nishizaki, Tomoyuki ^a   Ikeuchi, Youji ^a   Matsuoka, Toshiyuki ^a   Sumikawa, Katumi ^b  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ACh receptor; Ca2+, voltage clamp; linoleic acid; linolenic acid; protein kinase C; Xenopus oocytes

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; ACETYLCHOLINE; LINOLEIC ACID; NICOTINIC RECEPTOR; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEPRESSION; ELECTROPHYSIOLOGY; FEMALE; ION CURRENT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; VOLTAGE CLAMP; XENOPUS;

ACETYLCHOLINE; ALPHA-LINOLENIC ACID; ANIMALS; ELECTRIC CONDUCTIVITY; ENZYME INHIBITORS; FEMALE; INDOLES; ION CHANNEL GATING; ION CHANNELS; LINOLEIC ACID; LINOLEIC ACIDS; MALEIMIDES; MUTATION; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE C; RECEPTORS, CHOLINERGIC; TIME FACTORS; TORPEDO; XENOPUS;

EID: 0030981895     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01405-9     Document Type: Article

References (19)

1. B receptors regulate the induction of LTP, Nature, 338 (1989) 500-503.
2. Eusebi, F., Grassi, F., Nervi, C., Caporale, C., Adamo, S., Zani, B.M. and Molinaro, M., Acetylcholine may regulate its own nicotinic receptor-channel through the C-kinase system, Proc. R. Soc. London B230, (1987) 355-365.
3. Exon, J.H., Phosphatidylcholine breakdown and signal transduction, Biochim. Biophys. Acta, 1212 (1994) 26-42.
4. Fraster, D.D., Hoehn, K., Weiss, S. and MacVicar, B.A., Arachidonic acid inhibits sodium currents and synaptic transmission in cultured striatal neurons, Neuron, 11 (1993) 633-644.
5. Gehle, V.M. and Sumikawa, K., Site-directed mutagenesis of the conserved N-glycosylation site on the nicotinic acetylcholine receptor subunits, Mol. Brain Res., 11 (1991) 17-25.
6. Huganir, R.L., Regulation of the nicotinic acetylcholine receptor by protein phosphorylation, J. Rec. Res., 7 (1987) 241-256.
7. Hunter, B.E., de Fiebre, C.M., Papke, R.L., Kem, W.R. and Meyer, E.M., A novel nicotinic agonist facilitates induction of long-term potentiation in the rat hippocampus, Neurosci. Lett., 168 (1994)130-134.
8. Ikeuchi, Y., Nishizaki, Y., Matsuoka, T. and Sumikawa, K., Arachidonic acid potentiates ACh receptor currents by protein kinase C activation but not by receptor phosphorylation, Biochem. Biophys. Res. Commun., 221 1996 716-721.
9. Markram, H. and Segal, M., Long-lasting facilitation of excitatory postsynaptic potentials in the rat hippocampus by acetylcholine, J. Physiol, 427 (1990) 381-393.
10. Miledi, R. and Parker, I., Chloride current induced by injection of calcium into Xenopus oocytes, J. Physiol., 357 (1984) 173-183.
11. Miller, B., Sarantis, M., Traynelis, S.F. and Attwell, D., Potentiation of NMDA receptor currents by arachidonic acid, Nature, 355 (1992) 722-725.
12. Nishizaki, T. and Ikeuchi, Y., Activation of endogenous protein kinase C enhances currents through α1 and α2 glycine receptor channels, Brain Res., 687 (1995) 214-216.
13. Nishizuka, Y., Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C, Science, 258 (1992) 607-614.
14. Nishizuka, Y., Protein kinase C and lipid signaling for sustained cellular responses, FASEB J., 9 (1995) 484-496.
15. Petrou, S., Ordway, R.W., Singer, J.J. and Walsh, J.V. Jr., A putative fatty acid-binding domain of the NMDA receptors, Trends Biochem. Sci., 18 1993 41-42.
16. Raymond, L.A., Blackstone, C.D. and Huganir, R.L., Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticity, Trends Neurosci., 16 (1993) 147-153.
17. Shimada, T. and Somlyo, A.P., Modulation of voltage-dependent Ca channel current by arachidonic acid and other long-chain fatty acids in rabbit intestinal smooth muscle, J. Gen. Physiol., 100 (1992) 27-44.
18. Sumikawa, K. and Miledi, R., Assembly and N-glycosylation of all ACh receptor subunits are required for their efficient insertion into plasma membranes, Mol. Brain Res., 5 (1989) 183-192.
19. Vijayaraghavan, S., Huang, B., Blumenthal, E.M. and Berg, D.K., Arachidonic acid as a possible negative feedback inhibitor of nicotinic acetylcholine receptors on neurons, J. Neurosci., 15 (1995) 3679-3687.