The linoleic acid derivative DCP-LA selectively activates PKC-ε, possibly binding to the phosphatidylserine binding site

Journal of Lipid Research

Volumn 47, Issue 6, 2006, Pages 1146-1156

  Kanno, Takeshi ^a   Yamamoto, Hideyuki ^a   Yaguchi, Takahiro ^a   Hi, Rika ^a   Mukasa, Takeshi ^a   Fujikawa, Hirokazu ^a   Nagata, Tetsu ^a   Yamamoto, Satoshi ^a   Tanaka, Akito ^b   Nishizaki, Tomoyuki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b Reverse Proteomics Research Institute Co Ltd   (Japan)

Author keywords

8 2 (2 pentyl cyclopropylmethyl) cyclopropyl octanoic acid; Protein kinase C ; Protein kinase C

Indexed keywords

1,2 DIOLEOYL SN GLYCEROL; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 8 [2 (2 PENTYLCYCLOPROPYLMETHYL)CYCLOPROPYL]OCTANOIC ACID; DIOLEOYLPHOSPHATIDYLSERINE; ISOENZYME; LINOLEIC ACID; PHOSPHATIDYLSERINE; PROTEIN KINASE C EPSILON; PROTEIN KINASE C GAMMA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL STRAIN; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; ENZYME INHIBITION; ENZYME MECHANISM; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; ISOENZYMES; LINOLEIC ACIDS; OCTANOIC ACIDS; PC12 CELLS; PHOSPHATIDYLSERINES; PROTEIN KINASE C; PROTEIN KINASE C-EPSILON; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SUBSTRATE SPECIFICITY;

EID: 33744828259     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M500329-JLR200     Document Type: Article

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