-
1
-
-
3543097547
-
Suppressor T cells in human diseases
-
Baecher-Allan C., Hafler D.A. Suppressor T cells in human diseases. J. Exp. Med. 2004, 200:273-276.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 273-276
-
-
Baecher-Allan, C.1
Hafler, D.A.2
-
2
-
-
33746356813
-
Human regulatory T cells and their role in autoimmune disease
-
Baecher-Allan C., Hafler D.A. Human regulatory T cells and their role in autoimmune disease. Immunol. Rev. 2006, 212:203-216.
-
(2006)
Immunol. Rev.
, vol.212
, pp. 203-216
-
-
Baecher-Allan, C.1
Hafler, D.A.2
-
4
-
-
18144366988
-
Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cells
-
Baecher-Allan C., Wolf E., Hafler D.A. Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cells. Clin. Immunol. 2005, 115:10-18.
-
(2005)
Clin. Immunol.
, vol.115
, pp. 10-18
-
-
Baecher-Allan, C.1
Wolf, E.2
Hafler, D.A.3
-
5
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
6
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E., Carrier Y., Gao W., Korn T., Strom T.B., Oukka M., Weiner H.L., Kuchroo V.K. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006, 441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
7
-
-
33746630543
-
MicroRNA control of lifespan and metabolism
-
Boehm M., Slack F.J. MicroRNA control of lifespan and metabolism. Cell Cycle 2006, 5:837-840.
-
(2006)
Cell Cycle
, vol.5
, pp. 837-840
-
-
Boehm, M.1
Slack, F.J.2
-
8
-
-
19544382508
-
Elimination of both CD4+ and CD8+ T cells but not B cells eliminates inflammation and prolongs the survival of TGFbeta1-deficient mice
-
Bommireddy R., Engle S.J., Ormsby I., Boivin G.P., Babcock G.F., Doetschman T. Elimination of both CD4+ and CD8+ T cells but not B cells eliminates inflammation and prolongs the survival of TGFbeta1-deficient mice. Cell. Immunol. 2004, 232:96-104.
-
(2004)
Cell. Immunol.
, vol.232
, pp. 96-104
-
-
Bommireddy, R.1
Engle, S.J.2
Ormsby, I.3
Boivin, G.P.4
Babcock, G.F.5
Doetschman, T.6
-
9
-
-
0348223787
-
- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 2003, 198:1875-1886.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
10
-
-
33750499991
-
A role for Dicer in immune regulation
-
Cobb B.S., Hertweck A., Smith J., O'Connor E., Graf D., Cook T., Smale S.T., Sakaguchi S., Livesey F.J., Fisher A.G., Merkenschlager M. A role for Dicer in immune regulation. J. Exp. Med. 2006, 203:2519-2527.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2519-2527
-
-
Cobb, B.S.1
Hertweck, A.2
Smith, J.3
O'Connor, E.4
Graf, D.5
Cook, T.6
Smale, S.T.7
Sakaguchi, S.8
Livesey, F.J.9
Fisher, A.G.10
Merkenschlager, M.11
-
11
-
-
0037029424
-
Multiple sclerosis
-
Compston A., Coles A. Multiple sclerosis. Lancet 2002, 359:1221-1231.
-
(2002)
Lancet
, vol.359
, pp. 1221-1231
-
-
Compston, A.1
Coles, A.2
-
12
-
-
33947644716
-
Cutting edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells
-
Davidson T.S., DiPaolo R.J., Andersson J., Shevach E.M. Cutting edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells. J. Immunol. 2007, 178:4022-4026.
-
(2007)
J. Immunol.
, vol.178
, pp. 4022-4026
-
-
Davidson, T.S.1
DiPaolo, R.J.2
Andersson, J.3
Shevach, E.M.4
-
14
-
-
33846817153
-
Increased frequency of CD4+ CD25+ regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients
-
Feger U., Luther C., Poeschel S., Melms A., Tolosa E., Wiendl H. Increased frequency of CD4+ CD25+ regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients. Clin. Exp. Immunol. 2007, 147:412-418.
-
(2007)
Clin. Exp. Immunol.
, vol.147
, pp. 412-418
-
-
Feger, U.1
Luther, C.2
Poeschel, S.3
Melms, A.4
Tolosa, E.5
Wiendl, H.6
-
15
-
-
33244469494
-
CD25 regulatory T cells determine secondary but not primary remission in EAE: impact on long-term disease progression
-
Gartner D., Hoff H., Gimsa U., Burmester G.R., Brunner-Weinzierl M.C. CD25 regulatory T cells determine secondary but not primary remission in EAE: impact on long-term disease progression. J. Neuroimmunol. 2006, 172:73-84.
-
(2006)
J. Neuroimmunol.
, vol.172
, pp. 73-84
-
-
Gartner, D.1
Hoff, H.2
Gimsa, U.3
Burmester, G.R.4
Brunner-Weinzierl, M.C.5
-
16
-
-
0034131557
-
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
-
Gorelik L., Flavell R.A. Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 2000, 12:171-181.
-
(2000)
Immunity
, vol.12
, pp. 171-181
-
-
Gorelik, L.1
Flavell, R.A.2
-
18
-
-
28444469246
-
Silencing of microRNAs in vivo with 'antagomirs'
-
Krutzfeldt J., Rajewsky N., Braich R., Rajeev K.G., Tuschl T., Manoharan M., Stoffel M. Silencing of microRNAs in vivo with 'antagomirs'. Nature 2005, 438:685-689.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
Stoffel, M.7
-
19
-
-
0027724228
-
Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease
-
Kulkarni A.B., Karlsson S. Transforming growth factor-beta 1 knockout mice. A mutation in one cytokine gene causes a dramatic inflammatory disease. Am. J. Pathol. 1993, 143:3-9.
-
(1993)
Am. J. Pathol.
, vol.143
, pp. 3-9
-
-
Kulkarni, A.B.1
Karlsson, S.2
-
20
-
-
51049110261
-
Dicer-dependent microRNA pathway safeguards regulatory T cell function
-
Liston A., Lu L.F., O'Carroll D., Tarakhovsky A., Rudensky A.Y. Dicer-dependent microRNA pathway safeguards regulatory T cell function. J. Exp. Med. 2008, 205:1993-2004.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1993-2004
-
-
Liston, A.1
Lu, L.F.2
O'Carroll, D.3
Tarakhovsky, A.4
Rudensky, A.Y.5
-
21
-
-
38849209304
-
Not miR-ly small RNAs: big potential for microRNAs in therapy
-
Love T.M., Moffett H.F., Novina C.D. Not miR-ly small RNAs: big potential for microRNAs in therapy. J. Allergy Clin. Immunol. 2008, 121:309-319.
-
(2008)
J. Allergy Clin. Immunol.
, vol.121
, pp. 309-319
-
-
Love, T.M.1
Moffett, H.F.2
Novina, C.D.3
-
22
-
-
55849126729
-
Patients with relapsing-remitting multiple sclerosis have normal Treg function when cells expressing IL-7 receptor alpha-chain are excluded from the analysis
-
Michel L., Berthelot L., Pettre S., Wiertlewski S., Lefrere F., Braudeau C., Brouard S., Soulillou J.P., Laplaud D.A. Patients with relapsing-remitting multiple sclerosis have normal Treg function when cells expressing IL-7 receptor alpha-chain are excluded from the analysis. J. Clin. Invest. 2008, 118:3411-3419.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3411-3419
-
-
Michel, L.1
Berthelot, L.2
Pettre, S.3
Wiertlewski, S.4
Lefrere, F.5
Braudeau, C.6
Brouard, S.7
Soulillou, J.P.8
Laplaud, D.A.9
-
23
-
-
34250841756
-
MicroRNAs in human cancer: from research to therapy
-
Negrini M., Ferracin M., Sabbioni S., Croce C.M. MicroRNAs in human cancer: from research to therapy. J. Cell Sci. 2007, 120:1833-1840.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 1833-1840
-
-
Negrini, M.1
Ferracin, M.2
Sabbioni, S.3
Croce, C.M.4
-
24
-
-
3242754344
-
Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3
-
Ostroukhova M., Seguin-Devaux C., Oriss T.B., Dixon-McCarthy B., Yang L., Ameredes B.T., Corcoran T.E., Ray A. Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3. J. Clin. Invest. 2004, 114:28-38.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 28-38
-
-
Ostroukhova, M.1
Seguin-Devaux, C.2
Oriss, T.B.3
Dixon-McCarthy, B.4
Yang, L.5
Ameredes, B.T.6
Corcoran, T.E.7
Ray, A.8
-
26
-
-
1842480959
-
TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes
-
Peng Y., Laouar Y., Li M.O., Green E.A., Flavell R.A. TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. Proc. Natl Acad. Sci. USA 2004, 101:4572-4577.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 4572-4577
-
-
Peng, Y.1
Laouar, Y.2
Li, M.O.3
Green, E.A.4
Flavell, R.A.5
-
27
-
-
54249158400
-
Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling
-
Petrocca F., Vecchione A., Croce C.M. Emerging role of miR-106b-25/miR-17-92 clusters in the control of transforming growth factor beta signaling. Cancer Res. 2008, 68:8191-8194.
-
(2008)
Cancer Res.
, vol.68
, pp. 8191-8194
-
-
Petrocca, F.1
Vecchione, A.2
Croce, C.M.3
-
28
-
-
55249100969
-
SiLEncing SLE: the power and promise of small noncoding RNAs
-
Rigby R.J., Vinuesa C.G. SiLEncing SLE: the power and promise of small noncoding RNAs. Curr. Opin. Rheumatol. 2008, 20:526-531.
-
(2008)
Curr. Opin. Rheumatol.
, vol.20
, pp. 526-531
-
-
Rigby, R.J.1
Vinuesa, C.G.2
-
29
-
-
33746369415
-
Regulatory T-cell physiology and application to treat autoimmunity
-
Tang Q., Bluestone J.A. Regulatory T-cell physiology and application to treat autoimmunity. Immunol. Rev. 2006, 212:217-237.
-
(2006)
Immunol. Rev.
, vol.212
, pp. 217-237
-
-
Tang, Q.1
Bluestone, J.A.2
-
30
-
-
0037076272
-
Diagnosis of multiple cancer types by shrunken centroids of gene expression
-
Tibshirani R., Hastie T., Narasimhan B., Chu G. Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc. Natl Acad. Sci. USA 2002, 99:6567-6572.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 6567-6572
-
-
Tibshirani, R.1
Hastie, T.2
Narasimhan, B.3
Chu, G.4
-
31
-
-
33744904725
-
Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression
-
Venken K., Hellings N., Hensen K., Rummens J.L., Medaer R., D'Hooghe M.B., Dubois B., Raus J., Stinissen P. Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression. J. Neurosci. Res. 2006, 83:1432-1446.
-
(2006)
J. Neurosci. Res.
, vol.83
, pp. 1432-1446
-
-
Venken, K.1
Hellings, N.2
Hensen, K.3
Rummens, J.L.4
Medaer, R.5
D'Hooghe, M.B.6
Dubois, B.7
Raus, J.8
Stinissen, P.9
-
32
-
-
37149003363
-
Compromised CD4+ CD25(high) regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level
-
Venken K., Hellings N., Thewissen M., Somers V., Hensen K., Rummens J.L., Medaer R., Hupperts R., Stinissen P. Compromised CD4+ CD25(high) regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level. Immunology 2008, 123:79-89.
-
(2008)
Immunology
, vol.123
, pp. 79-89
-
-
Venken, K.1
Hellings, N.2
Thewissen, M.3
Somers, V.4
Hensen, K.5
Rummens, J.L.6
Medaer, R.7
Hupperts, R.8
Stinissen, P.9
-
33
-
-
39749143354
-
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters
-
Ventura A., Young A.G., Winslow M.M., Lintault L., Meissner A., Erkeland S.J., Newman J., Bronson R.T., Crowley D., Stone J.R., Jaenisch R., Sharp P.A., Jacks T. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell 2008, 132:875-886.
-
(2008)
Cell
, vol.132
, pp. 875-886
-
-
Ventura, A.1
Young, A.G.2
Winslow, M.M.3
Lintault, L.4
Meissner, A.5
Erkeland, S.J.6
Newman, J.7
Bronson, R.T.8
Crowley, D.9
Stone, J.R.10
Jaenisch, R.11
Sharp, P.A.12
Jacks, T.13
-
34
-
-
1842732224
-
Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
-
Viglietta V., Baecher-Allan C., Weiner H.L., Hafler D.A. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J. Exp. Med. 2004, 199:971-979.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 971-979
-
-
Viglietta, V.1
Baecher-Allan, C.2
Weiner, H.L.3
Hafler, D.A.4
-
35
-
-
58149085504
-
MicroRNA control in the immune system: basic principles
-
Xiao C., Rajewsky K. MicroRNA control in the immune system: basic principles. Cell 2009, 136:26-36.
-
(2009)
Cell
, vol.136
, pp. 26-36
-
-
Xiao, C.1
Rajewsky, K.2
-
36
-
-
0035876913
-
A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood
-
Yamagiwa S., Gray J.D., Hashimoto S., Horwitz D.A. A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood. J. Immunol. 2001, 166:7282-7289.
-
(2001)
J. Immunol.
, vol.166
, pp. 7282-7289
-
-
Yamagiwa, S.1
Gray, J.D.2
Hashimoto, S.3
Horwitz, D.A.4
-
38
-
-
1242290580
-
- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10
-
- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. J. Immunol. 2004, 172:5213-5221.
-
(2004)
J. Immunol.
, vol.172
, pp. 5213-5221
-
-
Zheng, S.G.1
Wang, J.H.2
Gray, J.D.3
Soucier, H.4
Horwitz, D.A.5
-
39
-
-
33644835247
-
TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells
-
Zheng S.G., Wang J.H., Stohl W., Kim K.S., Gray J.D., Horwitz D.A. TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells. J. Immunol. 2006, 176:3321-3329.
-
(2006)
J. Immunol.
, vol.176
, pp. 3321-3329
-
-
Zheng, S.G.1
Wang, J.H.2
Stohl, W.3
Kim, K.S.4
Gray, J.D.5
Horwitz, D.A.6
-
40
-
-
33847220736
-
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
-
Zheng Y., Josefowicz S.Z., Kas A., Chu T.T., Gavin M.A., Rudensky A.Y. Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature 2007, 445:936-940.
-
(2007)
Nature
, vol.445
, pp. 936-940
-
-
Zheng, Y.1
Josefowicz, S.Z.2
Kas, A.3
Chu, T.T.4
Gavin, M.A.5
Rudensky, A.Y.6
-
41
-
-
51049120236
-
Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity
-
Zhou X., Jeker L.T., Fife B.T., Zhu S., Anderson M.S., McManus M.T., Bluestone J.A. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J. Exp. Med. 2008, 205:1983-1991.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1983-1991
-
-
Zhou, X.1
Jeker, L.T.2
Fife, B.T.3
Zhu, S.4
Anderson, M.S.5
McManus, M.T.6
Bluestone, J.A.7
|