Increased mitochondrial stress and modulation of mitochondrial respiratory enzyme activities in acetaminophen-induced toxicity in mouse macrophage cells

Food and Chemical Toxicology

Volumn 48, Issue 10, 2010, Pages 2624-2632

  Al Belooshi, Thekra ^a   John, Annie ^a   Tariq, Saeed ^a   Al Otaiba, Amna ^a   Raza, Haider ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Acetaminophen; Apoptosis; Macrophages; Mitochondria; Oxidative stress; Respiratory enzymes

Indexed keywords

CASPASE 3; CYCLOOXYGENASE 2; DNA; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PARACETAMOL; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL STRESS; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME ACTIVITY; MACROPHAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION;

ACETAMINOPHEN; ADENOSINE TRIPHOSPHATE; ANALGESICS, NON-NARCOTIC; ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CYTOCHROME P-450 CYP2E1; DNA FRAGMENTATION; ENZYME ACTIVATION; MACROPHAGES; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA; NECROSIS; NITRIC OXIDE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

ANIMALIA;

EID: 77956341174     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.06.031     Document Type: Article

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