Expression of NES-hTERT in cancer cells delays cell cycle progression and increases sensitivity to genotoxic stress

PLoS ONE

Volumn 5, Issue 5, 2010, Pages

  Kovalenko, Olga A ^a   Kaplunov, Jessica ^a   Herbig, Utz ^a   detoledo, Sonia ^a   Azzam, Edouard I ^a   Santos, Janine H ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGAR; DNA; HYDROGEN PEROXIDE; TELOMERASE REVERSE TRANSCRIPTASE; MITOCHONDRIAL DNA; TELOMERASE; TERT PROTEIN, HUMAN;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CATALYSIS; CELL CYCLE PROGRESSION; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL STRAIN LNCAP; CELL STRESS; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; ENZYME ACTIVITY; FIBROBLAST; GENE MUTATION; GENOTOXICITY; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IONIZING RADIATION; NUCLEAR EXPORT SIGNAL; NUCLEAR LOCALIZATION SIGNAL; PROTEIN EXPRESSION; SENESCENCE; TELOMERE; CELL ADHESION; CELL CYCLE; CELL SHAPE; DRUG SCREENING; ENZYMOLOGY; GENETICS; MALE; METABOLISM; PATHOLOGY; PROSTATE TUMOR; SKIN TUMOR; TUMOR CELL LINE;

NES;

CELL ADHESION; CELL CYCLE; CELL LINE, TUMOR; CELL SHAPE; DNA DAMAGE; DNA, MITOCHONDRIAL; HUMANS; MALE; NUCLEAR EXPORT SIGNALS; PROSTATIC NEOPLASMS; SKIN NEOPLASMS; TELOMERASE; TELOMERE; TUMOR STEM CELL ASSAY;

EID: 77956269805     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010812     Document Type: Article

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