Evidence that high telomerase activity may induce a senescent-like growth arrest in human fibroblasts

Journal of Biological Chemistry

Volumn 278, Issue 9, 2003, Pages 7692-7698

  Gorbunova, Vera ^a   Seluanov, Andrei ^c   Pereira Smith, Olivia M ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; MOLECULAR BIOLOGY;

IMMORTAL CELLS;

BIOCHEMISTRY;

BETA GALACTOSIDASE; PROTEIN P21; RAF PROTEIN; RAS PROTEIN; RETINOBLASTOMA PROTEIN; TELOMERASE; TRANSCRIPTION FACTOR E2F; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; DNA BINDING PROTEIN;

ARTICLE; CELL CULTURE; CELL IMMORTALIZATION; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SUBPOPULATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; EVIDENCE BASED MEDICINE; FIBROBLAST; FLOW CYTOMETRY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GROWTH DISORDER; HUMAN; HUMAN CELL; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; SIGNAL TRANSDUCTION; TELOMERE; CELL AGING; CELL DIVISION; CELL LINE; CHEMISTRY; METABOLISM; WESTERN BLOTTING;

BETA-GALACTOSIDASE; BLOTTING, WESTERN; CELL AGING; CELL DIVISION; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA-BINDING PROTEINS; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; PHENOTYPE; RETINOBLASTOMA PROTEIN; TELOMERASE; TELOMERE; TRANSFECTION;

EID: 0037470231     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212944200     Document Type: Article

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