Biochemical disorders induced by cytotoxic marine natural products in breast cancer cells as revealed by proton NMR spectroscopy-based metabolomics

Biochemical Pharmacology

Volumn 80, Issue 8, 2010, Pages 1170-1179

  Bayet Robert, Mathilde ^a,b   Lim, Suzanne ^a   Barthomeuf, Chantal ^a   Morvan, Daniel ^a,b  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b Centre Regional de Lutte Contre le Cancer Jean Perrin   (France)

Author keywords

Apoptosis; Marine natural products; MCF7 breast tumor cells; Metabolic targets; NMR spectroscopy based metabolomics

Indexed keywords

ANTINEOPLASTIC AGENT; ASCIDIDEMIN; ASPARTIC ACID; CITRIC ACID; GLUCONIC ACID; KAHALALIDE F; LACTIC ACID; LAMELLARIN D; MALIC ACID; NATURAL PRODUCT; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID; UNCLASSIFIED DRUG; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; BREAST CANCER; CELL DEATH; CHEMICAL ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA CONTENT; HUMAN; HUMAN CELL; LIPID STORAGE; METABOLOMICS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; ADENOCARCINOMA; BREAST NEOPLASMS; DRUG DELIVERY SYSTEM; DRUG EFFECTS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES; TUMOR CELL LINE;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; METABOLIC NETWORKS AND PATHWAYS; METABOLOMICS; NEOPLASM PROTEINS;

EID: 77956229338     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.07.007     Document Type: Article

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