Inhibition of mitochondrial respiration mediates apoptosis induced by the anti-tumoral alkaloid lamellarin D

Apoptosis

Volumn 15, Issue 7, 2010, Pages 769-781

  Ballot, Caroline ^a   Kluza, Jérome ^a   Lancel, Steve ^b   Martoriati, Alain ^a   Hassoun, Sidi Mohamed ^b   Mortier, Laurent ^a   Vienne, Jean Claude ^c   Briand, Gilbert ^c   Formstecher, Pierre ^a   Bailly, Christian ^a,d   Nevière, Remi ^b   Marchetti, Philippe ^a,c  

^a JEAN PIERRE AUBERT RESEARCH CENTER   (France)

^b France Institut Pasteur de Lille   (France)

^c LILLE UNIVERSITY HOSPITAL   (France)

^d INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

Apoptosis; Cancer; Chemotherapy; Metabolism; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC ALKALOID; CYCLOSPORIN A; CYTOCHROME C; LAMELLARIN D; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CARRIER PROTEIN; COUMARIN DERIVATIVE; FUSED HETEROCYCLIC RINGS; ISOQUINOLINE DERIVATIVE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CANCER CELL; CELL ISOLATION; CELL SWELLING; CONTROLLED STUDY; DRUG EXPOSURE; DRUG MECHANISM; HEART MITOCHONDRION; HUMAN; HUMAN CELL; MELANOMA CELL; MICROSOME; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RESPIRATORY CHAIN; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL RESPIRATION; CHEMISTRY; DRUG EFFECT; LEUKEMIA CELL LINE; METABOLISM; MITOCHONDRION; OXYGEN CONSUMPTION; RAT; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL RESPIRATION; COUMARINS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HUMANS; ISOQUINOLINES; JURKAT CELLS; MICE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; OXYGEN CONSUMPTION; RATS;

EID: 77954586489     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-010-0471-2     Document Type: Article

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