Apaf-1-deficient fog mouse cell apoptosis involves hypo-polarization of the mitochondrial inner membrane, ATP depletion and citrate accumulation

Cell Research

Volumn 18, Issue 12, 2008, Pages 1210-1219

  Katoh, Iyoko ^a   Sato, Shingo ^b   Fukunishi, Nahoko ^b   Yoshida, Hiroki ^c   Imai, Takasuke ^b   Kurata, Shun Ichi ^b  

^a UNIVERSITY OF YAMANASHI   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c SAGA UNIVERSITY   (Japan)

Author keywords

Apaf 1; Apoptosis; ATP; Caspase 9; Citrate; Mitochondria

Indexed keywords

ADENOSINE TRIPHOSPHATE; APAF1 PROTEIN, MOUSE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASP9 PROTEIN, MOUSE; CASPASE 9; CITRIC ACID;

ANIMAL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL CULTURE; FIBROBLAST; GENETICS; METABOLISM; MITOCHONDRIAL MEMBRANE; MOUSE; MOUSE MUTANT; OXIDATIVE STRESS; SPLEEN;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BONE MARROW CELLS; CASPASE 9; CELLS, CULTURED; CITRIC ACID; FIBROBLASTS; MICE; MICE, MUTANT STRAINS; MITOCHONDRIAL MEMBRANES; OXIDATIVE STRESS; SPLEEN;

MUS;

EID: 57049189721     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2008.87     Document Type: Article

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