Drosotoxin, a selective inhibitor of tetrodotoxin-resistant sodium channels

Biochemical Pharmacology

Volumn 80, Issue 8, 2010, Pages 1296-1302

  Zhu, Shunyi ^a   Gao, Bin ^a   Deng, Meichun ^b   Yuan, Yuzhe ^a   Luo, Lan ^a   Peigneur, Steve ^c   Xiao, Yucheng ^b   Liang, Songping ^b   Tytgat, Jan ^c  

^a INSTITUTE OF ZOOLOGY   (China)

^b HUNAN NORMAL UNIVERSITY   (China)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Defensin; Drosomycin; Drosotoxin; Scorpion toxin; Venomous arthropod

Indexed keywords

(1 BUTYLAMINO 3 METHYLBUTYL)(1 PYRROLIDINYL) KETONE; ANTIFUNGAL AGENT; BMKITC; CALCIUM ION; DEFENSIN; DROSOMYCIN; DROSOTOXIN; ION CHANNEL; POTASSIUM ION; SODIUM CHANNEL; TETRODOTOXIN; TOXIN; UNCLASSIFIED DRUG; HYBRID PROTEIN; SCORPION VENOM; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DROSOPHILA; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; FEMALE; GENE; IC 50; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SPINAL CORD NERVE CELL; SPINAL GANGLION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TIPE GENE; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; EVOLUTION; GENETICS; MOLECULAR GENETICS; SCORPION;

AMINO ACID SEQUENCE; ANIMALS; EVOLUTION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RATS; RECOMBINANT FUSION PROTEINS; SCORPION VENOMS; SCORPIONS; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN; TOXINS, BIOLOGICAL; BIOLOGICAL EVOLUTION;

EID: 77956227894     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.07.008     Document Type: Article

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