Dentate gyrus formation requires Emx2

Development

Volumn 122, Issue 12, 1996, Pages 3893-3898

  Pellegrini, M ^a,d   Mansouri, A ^a   Simeone, A ^b   Boncinelli, E ^c,e   Gruss, P ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^c SAN RAFFAELE HOSPITAL   (Italy)

^d Sezione di Istol Embriol e Genet   (Italy)

^e CNR   (Italy)

Author keywords

Cerebral cortex; Cerebral hemispheres; Dentate gyrus; Emx2; Medial limbic cortex; Telencephalon

Indexed keywords

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; DENTATE GYRUS; EMBRYO DEVELOPMENT; FOREBRAIN; GENE EXPRESSION; HIPPOCAMPUS; LIMBIC CORTEX; MOUSE; NEUROEPITHELIUM; NONHUMAN; OLFACTORY BULB; PRIORITY JOURNAL;

ANIMALS; BRAIN; DENTATE GYRUS; GENES, LETHAL; HIPPOCAMPUS; HOMEODOMAIN PROTEINS; LIMBIC SYSTEM; MICE; MICE, MUTANT STRAINS; NERVE TISSUE PROTEINS; TRANSCRIPTION FACTORS; UROGENITAL ABNORMALITIES; UROGENITAL SYSTEM;

EID: 0030482082     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Altman, J. and Bayer, S. A. (1990a). Mosaic organization of the hippocampal neuroepithelium and the multiple germinal sources of dentate granule cells. J. Comp. Neurol. 301, 325-342.
2. Altman, J. and Bayer, S. A. (1990b). Migration and distribution of two populations of hippocampal granule cells precursors during the perinatal and postnatal periods. J. Comp. Neurol. 301, 365-381.
3. Alvarez-Bolado, G., Rosenfeld, M. G. and Swanson, L. W. (1995). Model of forebrain regionalization based on spatiotemporal patterns of Pou-III homeobox gene expression, birthdates, and morphological features. J. Comp. Neurol. 355, 237-295.
4. Bayer, S. A. and Altman J. (1991). Development of the limbic cortical areas. In Neocortical Development (ed. Bayer and Altman), pp 186-202. New York: Raven Press.
5. Bliss, E. M. and Lomo T. (1973). Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J. Physiol. 232, 331-356.
6. Brunelli, S., Faiella, A., Capra, V., Nigro, V., Simeone, A., Cama, A. and Boncinelli, E. (1996). Germline mutations in the homeobox gene EMX2 in patients with severe schizencephaly. Nature Genetics 12, 94-96.
7. Bunsey, M. and Eichenbaum, H. (1996). Conservation of hippocampal memory function in rats and humans. Nature 379, 255-257.
8. Capecchi, M. R. (1989). Altering the genome by homologous recombination. Science 244, 1288-1292.
9. Caviness, V. S. Jr, Takahashi, T. and Nowakowski, R. S. (1995). Numbers, time and neocortical neurogenesis: a general developmental and evolutionary model. Trends Neurosci. 18, 379-383.
10. Chalepakis, G., Stoykova, A., Wijnholds, J., Tremblay, P. and Gruss, P. (1993). Pax: gene regulators in the developing nervous system. J. Neurobiol. 24, 1367-1384.
11. Cowan, W. N., Stanfield, B. B. and Kishi, K. (1980). The development of the dentate gyrus. Curr. Top. Dev. Biol. 15, 103-157.
12. Echelard, Y., Epstein, D. J., St-Jacques, B., Shen, L., Mphler, J., McMahon, J. A., and McMahon, A. P. (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.
13. Emerich, D. F. and Walsh, T. J. (1990). Cholinergic cell loss and cognitive impairments following intraventricular or intradentate injection of colchicine. Brain Res. 517, 157-167.
14. Gulisano, M., Broccoli, V., Pardini, C., Boncinelli, E. (1996). Emx1 and Emx2 show different patterns of expression during proliferation and differentiation of the developing cerebral cortex. Europ. J. Neurosci. 8, 1037-1050.
15. Lowenstein D. H., Thomas M. J., Smith, D. H., and McIntosh T. C. (1992). Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus. J. Neurosci. 12, 4846-4853.
16. McNaughton, B. L, Barnes, C. A., Meltzer, J. and Sutherland, R. J. (1989). Hippocampal granule cells are necessary for normal spatial learning but not for spatially-selective pyramidal cell discharge. Exp. Brain Res. 76, 485-496.
17. Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W. and Roder, J. C. (1993a). Derivation of completely cell culture-derived mice from early-passage embryonic stem cell. Proc. Natl. Acad. Sci. USA 90, 8424-8428.
18. Nagy, A. and Rossant, J., (1993b). Production of completely ES cells-derived fetuses. In Gene Targeting, A Pratical Approach, (ed. A. Joyner), pp. 147-179. Oxford: IRL Press.
19. Porteus, M., Bulfone, A., Ciaranello, R. D. and Rubenstein, J. L. R. (1991). Isolation and characterization of a novel cDNA clone encoding a homeodomain that is developmentally regulated in the ventral forebrain. Neuron 7, 221-229.
20. Price, M., Lemaistre, M., Pischetola, M., Di Lauro, R. and Doboule, D. (1991). A mouse gene related to Distall-less shows a restricted expression in the developing forebrain. Nature 351, 748-751.
21. Price, M., Lazzaro, D., Pohl, T., Mattei, M. G., Ruther, U., Olivo, J. C. and Duboule, D. (1992). Regional expression of the homeobox gene Nkx-2. 2 in the developing mammalian forebrain. Neuron 8, 241-255.
22. Rager, G., Lausmann, S. and Gallyas, F. (1979). An improved silver stain for developing nervous tissue. Stain Technol. 54, 193-199.
23. Rakic, P. (1995). A small step for the cell, a giant leap for mankind: a hypothesis of neocortical expansion during evolution. Trends Neurosci. 18, 383-388.
24. Reznikov, K. Y. (1991). Cell proliferation and cytogenesis in the mouse hippocampus. Adv. Anat. Embryol. Cell Biol. 122, 1-74.
25. Robertson, E. J. (1987). Embryo-derived stem cell lines. In Teratocarcinomas and Embryonic Stem Cell: A Pratical Approach (ed. Robertson, E. J.), pp. 71-112. Washington: IRL Press.
26. Shatz C. J. (1992). Dividing up the neocortex. Science 258, 237-238.
27. Simeone, A., Gulisano, M., Acampora, D., Stornaiuolo, A., Rambaldi, M. and Boncinelli, E. (1992a). Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J. 11, 2541-2550.
28. Simeone, A., Acampora, D., Gulisano, M., Stornaiuolo, A. and Boncinelli, E. (1992b). Nested expression domains of four homeobox genes in developing rostral brain. Nature 358, 687-690.
29. Simeone, A., Acampora, D., Mallamaci, A., Stornaiuolo, A., D'Aprice, M. R., Nigro, V. and Boncinelli, E. (1993). A vetebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J. 12, 2735-2747.
30. Sloviter R. S. (1994). The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy. Ann. Neurol. 35, 640-654.
31. Soriano, P., Montgomery, C., Geske, R. and Bradley, A. (1991). Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64, 693-702.
32. Squire, L. R. and Zola-Morgan, S. (1991). The medial temporal lobe memory system. Science 253, 1380-1386.
33. Stanfield B. B. and Cowan W. M. (1979a). The morphology of the hippocampus and dentate gyrus in normal and reeler mice. J. Comp. Neurol. 185, 393-422.
34. Stanfield B. B. and Cowan W. M. (1979b). The development of the hippocampus and dentate gyrus in normal and reeler mice. J. Comp. Neurol. 185, 423-459.
35. Stanfield B. B. and Cowan W. M. (1988). The development of the hippocampal region. In Cerebral Cortex (ed. Edward G. Jones and Alan Peters), pp. 91-131. New York: Plenum Press.
36. Stoykova, A. and Gruss, P. (1994). Roles of Pax-genes in developing and adult brain as suggested by expression pattern. J. Neurosci. 14, 1395-1412.
37. Stoykova, A., Walther C., Fritsch R. and Gruss P. (1996). Forebrain patterning defects in Pax6/Small eye mutant mice. Development 122, 3453-3465.
38. Tao, W. and Lai, E. (1992). Telencephalon-restricted expression of BF-1, a new member of the HNF-3/fork head gene family, in the developing rat brain. Neuron 8, 957-966.
39. Vaher, P. R., Luine, V. N., Gould, E. and McEwen, B. S. (1994). Effects of adrenalectomy on spatial memory performance and dentate gyrus morphology. Brain Res. 656, 71-78.
40. Victor, M. and Agamanolis, D. (1990). Amnesia due to lesions confined to the hippocampus: a clinical-pathologic study. J. Cognit. Neurosci. 2, 246-257.
41. Xuan, S., Baptista, C. A., Balas, G., Tao, W., Soares, V. C. and Lai, E. (1995). Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron 14, 1141-1152.