Downregulation of programmed cell death 4 by inflammatory conditions contributes to the generation of the tumor promoting microenvironment

Molecular Carcinogenesis

Volumn 49, Issue 9, 2010, Pages 837-848

  Yasuda, Michiko ^a   Schmid, Tobias ^b   Rübsamen, Daniela ^b   Colburn, Nancy H ^c   Irie, Kazuhiro ^a   Murakami, Akira ^a  

^a KYOTO UNIVERSITY   (Japan)

^b GOETHE UNIVERSITY   (Germany)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Inflammation; Pdcd4; TNF

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CCL1 CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PROGRAMMED DEATH 1 LIGAND 4; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; CARCINOGEN; RECOMBINANT GAMMA INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CELL STRAIN MCF 7; CELL STRAIN U937; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; MONOCYTE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR MICROENVIRONMENT; TUMOR PROMOTION; ANIMAL; APOPTOSIS; CELL LINE; DRUG EFFECT; GENETICS; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; MACROPHAGE; METABOLISM;

BACTERIA (MICROORGANISMS);

ANIMALS; APOPTOSIS; CARCINOGENS; CELL LINE; DOWN-REGULATION; FEMALE; HUMANS; INTERFERON-GAMMA; INTERFERON-GAMMA, RECOMBINANT; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; MACROPHAGES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED ICR; MONOCYTES; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 77956220253     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20660     Document Type: Article

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