H2O2 preferentially synergizes with nitroprusside to induce apoptosis associated with superoxide dismutase dysregulation in human melanoma irrespective of p53 status: Antagonism by o-phenanthroline

Chemico-Biological Interactions

Volumn 188, Issue 1, 2010, Pages 134-143

  Gomez Sarosi, Luis A ^a   Strasberg Rieber, Mary ^a   Rieber, Manuel ^a  

^a Instituto Venezolano de Investigaciones Cientificas Centro de Microbiologia y Biologia Celular   (Venezuela)

Author keywords

Fenton reaction; Laser scanning cytometry; Oxidative stress; P53; Superoxide dismutase imbalance

Indexed keywords

1,10 PHENANTHROLINE; ACETYLCYSTEINE; AMMONIUM SULFATE; COPPER ZINC SUPEROXIDE DISMUTASE; HYDROGEN PEROXIDE; IRON; MANGANESE SUPEROXIDE DISMUTASE; N ACETYL S NITROSOPENICILLAMINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITROPRUSSIDE SODIUM; POTASSIUM FERRICYANIDE; PROTEIN P53; SUPEROXIDE DISMUTASE; 1,10-PHENANTHROLINE; PHENANTHROLINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ANTAGONISM; DRUG POTENTIATION; ENZYME DEGRADATION; ENZYME INDUCTION; FENTON REACTION; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MELANOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATION REDUCTION STATE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; GENOTYPE; METABOLISM; PATHOLOGY;

APOPTOSIS; CELL PROLIFERATION; DRUG SYNERGISM; GENOTYPE; HUMANS; HYDROGEN PEROXIDE; MELANOMA; NITROPRUSSIDE; PHENANTHROLINES; SUPEROXIDE DISMUTASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77956180118     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.07.018     Document Type: Article

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