Mcl-1 cleavage and sustained phosphorylation of c-Jun-N-terminal kinase mediate melanoma apoptosis induced by 2-acetyl furanonaphthoquinone: Roles of bcl-2 and p53

Cancer Biology and Therapy

Volumn 7, Issue 8, 2008, Pages 1206-1211

  Rieber, Manuel ^a   Rieber, Mary Strasberg ^a  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

ERK activation; Mcl 1 cleavage; SP600125; UO126

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 2 ACETYL FURANONAPHTHOQUINONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN MDM2; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG SENSITIVITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MELANOMA CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

EID: 49749098513     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.7.8.6217     Document Type: Article

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