Cytoskeletal actin degradation induced by lovastatin in cardiomyocytes is mediated through caspase-2

Cell Biology International

Volumn 28, Issue 11, 2004, Pages 781-790

  Kong, Jennifer Y ^a   Rabkin, Simon W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Actin; Cardiomyocyte; Caspase inhibitors; Caspase 2; Caspase 3; Heart; Lovastatin; Palmitate

Indexed keywords

ACETYL COENZYME A; BENZYLOXYCARBONYLVALYLASPARTYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 2; CASPASE 3 INHIBITOR; CASPASE INHIBITOR; DRUG METABOLITE; F ACTIN; MEVALONIC ACID; MEVINOLIN; PALMITIC ACID; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL METABOLISM; CELL STRUCTURE; CHICKEN; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; CYTOSKELETON; DRUG EFFECT; DRUG MECHANISM; EMBRYO; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE; FLUORESCENCE ACTIVATED CELL SORTING; HEART MUSCLE CELL; NONHUMAN;

ACETYL COENZYME A; ACTINS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 2; CASPASES; CELLS, CULTURED; CHICK EMBRYO; CYSTEINE PROTEINASE INHIBITORS; CYTOSKELETON; FLOW CYTOMETRY; HEART; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LOVASTATIN; MYOCYTES, CARDIAC; OLIGOPEPTIDES; PALMITIC ACID;

EID: 9244235016     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellbi.2004.07.012     Document Type: Article

References (54)

1. C. Alvarez, and E.S. Sztul Brefeldin A (BFA) disrupts the organization of the microtubule and the actin cytoskeletons European Journal of Cell Biology 78 1999 1 14
2. R. Atencia, A. Asumendi, and M. Garcia-Sanz Role of cytoskeleton in apoptosis Vitamins and Hormones 58 2000 267 297
3. M. Bando, Y. Miyake, M. Shiina, M. Wachi, K. Nagai, and T. Kataoka Actin cytoskeleton is required for early apoptosis signaling induced by anti-Fas antibody but not Fas ligand in murine B lymphoma A20 cells Biochemical and Biophysical Research Communications 290 2002 268 274
4. M. Beil, J. Leser, M.P. Lutz, A. Gukovskaya, T. Seufferlein, and G. Lynch Caspase 8-mediated cleavage of plectin precedes F-actin breakdown in acinar cells during pancreatitis American Journal of Physiology. Gastrointestinal and Liver Physiology 282 2002 G450 G460
5. A. Caballero-Benitez, and J. Moran Caspase activation pathways induced by staurosporine and low potassium: role of caspase-2 Journal of Neuroscience Research 71 2003 383 396
6. Y.R. Chen, R. Kori, B. John, and T.H. Tan Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis Biochemical and Biophysical Research Communications 288 2001 981 989
7. W.C. Earnshaw, L.M. Martins, and S.H. Kaufmann Mammalian caspases: structure, activation, substrates, and functions during apoptosis Annual Review of Biochemistry 68 1999 383 424
8. R.G. Fenton, H. Kung, K.L. Longo, and M.R. Smith Regulation of intracellular actin polymerization by prenylated cellular proteins Journal of Cell Biology 117 1992 347 356
9. K.F. Ferri, and G. Kroemer Organelle-specific initiation of cell death pathways Nature Cell Biology 3 2001 E255 E263
10. J.L. Goldstein, and M.S. Brown Regulation of the mevalonate pathway Nature 343 1990 425 430
11. Y. Guo, S.M. Srinivasula, A. Druilhe, T. Fernandes-Alnemri, and E.S. Alnemri Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria Journal of Biological Chemistry 277 2002 13430 13437
12. M.O. Hengartner The biochemistry of apoptosis Nature 407 2000 770 776
13. N.E. Ivessa, D. Gravotta, C. De Lemos-Chiarandini, and G. Kreibich Functional protein prenylation is required for the brefeldin A-dependent retrograde transport from the Golgi apparatus to the endoplasmic reticulum Journal of Biological Chemistry 272 1997 20828 20834
14. W. Kabsch, G. Mannherz, D. Suck, E.F. Pai, and K.C. Holmes Atomic structure of the actin: DNA I complex Nature 347 1980 37 45
15. C. Kayalar, T. Ord, M.P. Testa, L.T. Zhong, and D.E. Bredesen Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition Proceedings of the National Academy of Sciences of the United States of America 93 1996 2234 2238
16. G. Koch, C. Benz, G. Schmidt, C. Olenik, and K. Aktories Role of Rho protein in lovastatin-induced breakdown of actin cytoskeleton Journal of Pharmacology and Experimental Therapeutics 283 1997 901 909
17. J.Y. Kong, and S.W. Rabkin Palmitate-induced apoptosis in cardiomyocytes is mediated through alterations in mitochondria: prevention by cyclosporin Biochimica et Biophysica Acta 55608 2000 1 11
18. S. Kook, H. Kim Do, S.R. Shim, W. Kim, J.S. Chun, and W.K. Song Caspase-dependent cleavage of tensin induces disruption of actin cytoskeleton during apoptosis Biochemical and Biophysical Research Communications 303 2003 37 45
19. S. Kothakota, T. Azuma, C. Reinhard, A. Klippel, J. Tang, and K. Chu Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis Science 278 1997 294 296
20. P. Lassus, X. Opitz-Araya, and Y. Lazebnik Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization Science 297 2002 1352 1354
21. M.G. Levee, M.I. Dabrowska, J.L. Lelli Jr., and D.B. Hinshaw Actin polymerization and depolymerization during apoptosis in HL-60 cells American Journal of Physiology 271 1996 C1981 C1992
22. H. Li, H. Zhu, C.J. Xu, and J. Yuan Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis Cell 94 1998 491 501
23. X. Li, L. Liu, J.C. Tupper, D.D. Bannerman, R.K. Winn, and S.M. Sebti Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells Journal of Biological Chemistry 277 2002 15309 15316
24. G.D. Lopaschuk, D.D. Belke, J. Gamble, T. Itoi, and B.O. Schonekess Regulation of fatty acid oxidation in the mammalian heart in health and disease Biochimica et Biophysica Acta 1213 1994 263 267
25. M. Mancini, C.E. Machamer, S. Roy, D.W. Nicholson, N.A. Thornberry, and L.A. Casciola-Rosen Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis Journal of Cell Biology 149 2000 603 612
26. S.S. Martin, and P. Leder Human MCF10A mammary epithelial cells undergo apoptosis following actin depolymerization that is independent of attachment and rescued by Bcl-2 Molecular and Cellular Biology 21 2001 6529 6536
27. T. Mashima, M. Naito, N. Fujita, K. Noguchi, and T. Tsuruo Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis Biochemical and Biophysical Research Communications 217 1995 1185 1192
28. S. Ono Regulation of actin filament dynamics by actin depolymerizing factor/cofilin and actin-interacting protein 1: new blades for twisted filaments Biochemistry 42 2003 13363 13370
29. C.H. Packman, and M.A. Lichtman Activation of neutrophils - measurement of actin conformational changes by flow cytometry Blood Cells 161 1990 193 205
30. S.J. Padayatty, M. Marcelli, T.C. Shao, and G.R. Cunningham Lovastatin-induced apoptosis in prostate stromal cells The Journal of Clinical Endocrinology and Metabolism 82 1997 1434 1439
31. G. Paroni, C. Henderson, C. Schneider, and C. Brancolini Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3 Journal of Biological Chemistry 276 2001 21907 21915
32. G. Paroni, C. Henderson, C. Schneider, and C. Brancolini Caspase-2 can trigger cytochrome C release and apoptosis from the nucleus Journal of Biological Chemistry 277 2002 15147 15161
33. S.W. Rabkin, and P. Sunga The effect of doxorubicin (adriamycin) on cytoplasmic microtubule system in cardiac cells Journal of Molecular and Cellular Cardiology 19 1987 1073 1083
34. S.W. Rabkin, and J.Y. Kong Nitroprusside induces cardiomyocyte death: interaction with hydrogen peroxide American Journal of Physiology. Heart and Circulatory Physiology 279 2000 H3089 H3100
35. S.W. Rabkin Prevention of staurosporine-induced cell death in cardiomyocytes is more dependent on caspase-2 than caspase-3 inhibition and is independent of sphingomyelinase activation and ceramide generation Archives of Biochemistry and Biophysics 390 2001 119 127
36. S.W. Rabkin, and J.Y. Kong Discordance between the effect of modulators of calcium on staurosporine-induced apoptosis and staurosporine-induced actin degradation Cell Biology International 26 2002 433 440
37. S.W. Rabkin, and J.Y. Kong Lovastatin-induced cardiac toxicity involves both oncotic and apoptotic cell death with the apoptotic component blunted by both caspase-2 and caspase-3 inhibitors Toxicology and Applied Pharmacology 193 2003 346 355
38. R. Rengan, H.D. Ochs, L.I. Sweet, M.L. Keil, W.T. Gunning, and N.A. Lachant Actin cytoskeletal function is spared, but apoptosis is increased, in WAS patient hematopoietic cells Blood 95 2000 1283 1292
39. J.D. Robertson, M. Enoksson, M. Suomela, B. Zhivotovsky, and S. Orrenius Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis Journal of Biological Chemistry 277 2002 29803 29809
40. E.J. Sanders, and E. Parker Ablation of axial structures activates apoptotic pathways in somite cells of the chick embryo Anatomy and Embryology 204 2001 389 398
41. P.D. Sarmiere, and J.R. Bamburg Regulation of the neuronal actin cytoskeleton by ADF/cofilin Journal of Neurobiology 58 2004 103 117
42. A.H. Stegh, H. Herrmann, S. Lampel, D. Weisenberger, K. Andra, and M. Seper Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis Molecular and Cellular Biology 20 2000 5665 5679
43. L. Stefanis, C.M. Troy, H. Qi, M.L. Shelanski, and L.A. Greene Caspase-2 (Nedd-2) processing and death of trophic factor-deprived PC12 cells and sympathetic neurons occur independently of caspase-3 (CPP32)-like activity Journal of Neuroscience 18 1998 9204 9215
44. A. Sgorbissa, R. Benetti, S. Marzinotto, C. Schneider, and C. Brancolini Caspase-3 and caspase-7 but not caspase-6 cleave Gas2 in vitro: implications for microfilament reorganization during apoptosis Journal of Cell Science 112 1999 4475 4482
45. Q. Song, T. Wei, S. Lees-Miller, E. Alnemri, D. Watters, and M.F. Lavin Resistance of actin to cleavage during apoptosis Proceedings of the National Academy of Sciences of the United States of America 94 1997 157 162
46. N. Suarez-Huerta, R. Mosselmans, J.E. Dumont, and B. Robaye Actin depolymerization and polymerization are required during apoptosis in endothelial cells Journal of Cellular Physiology 184 2000 239 245
47. R.V. Talanian, C. Quinlan, S. Trautz, M.C. Hackett, J.A. Mankovich, and D. Banach Substrate specificity of caspase family proteases Journal of Biological Chemistry 272 1997 9677 9682
48. C.M. Troy, and M.L. Shelanski Caspase-2 redux Cell Death and Differentiation 10 2003 101 107
49. B. Van De Water, M. Kruidering, and J.F. Nagelkerke F-actin disorganization in apoptotic cell death of cultured rat renal proximal tubular cells American Journal of Physiology 70 1996 F593 F603
50. B. Van De Water, I.B. Tijdens, A. Verbrugge, M. Huigsloot, A.A. Dihal, and J.L. Stevens Cleavage of the actin-capping protein alpha-adducin at Asp-Asp-Ser-Asp633-Ala by caspase-3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells Journal of Biological Chemistry 275 2000 25805 25813
51. S.R. White, P. Williams, K.R. Wojcik, S. Sun, P.S. Hiemstra, and K.F. Rabe Initiation of apoptosis by actin cytoskeletal derangement in human airway epithelial cells American Journal of Respiratory Cell and Molecular Biology 24 2001 282 294
52. B.B. Wolf, and D.R. Green Suicidal tendencies: apoptotic cell death by caspase family proteinases Journal of Biological Chemistry 274 1999 20049 20052
53. Y. Yamazaki, M. Tsuruga, D. Zhou, Y. Fujita, X. Shang, and Y. Dang Cytoskeletal disruption accelerates caspase-3 activation and alters the intracellular membrane reorganization in DNA damage-induced apoptosis Experimental Cell Research 259 2000 64 78
54. B. Zhivotovsky, A. Samali, A. Gahm, and S. Orrenius Caspases: their intracellular localization and translocation during apoptosis Cell Death and Differentiation 6 1999 644 651