The cobalamin precursor cobinamide detoxifies nitroprusside-generated cyanide

Experimental Biology and Medicine

Volumn 232, Issue 6, 2007, Pages 789-798

  Broderick, Kate E ^a   Balasubramanian, Maheswari ^a   Chan, Adriano ^a   Potluri, Prasanth ^b   Feala, Jake ^c   Belke, Darrell D ^a   McCulloch, Andrew ^c   Sharma, Vijay S ^a   Pilz, Renate B ^a   Bigby, Timothy D ^a,d   Boss, Gerry R ^a,e  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute hypertension; Cobinamide; Cyanide; Nitric oxide; Nitroprusside

Indexed keywords

COBALAMIN DERIVATIVE; COBAMAMIDE; CYANIDE; NITRIC OXIDE; NITROPRUSSIDE SODIUM;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYANIDE TOXICITY; DETOXIFICATION; DROSOPHILA MELANOGASTER; DRUG BINDING; DRUG EFFECT; DRUG EFFICACY; INTOXICATION; MALE; MAMMAL CELL; MOUSE; NONHUMAN; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIHYPERTENSIVE AGENTS; CELLS, CULTURED; COBAMIDES; CYANIDES; DROSOPHILA MELANOGASTER; HEART RATE; MALE; MALPIGHIAN TUBULES; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MYOCYTES, SMOOTH MUSCLE; NITRATES; NITRIC OXIDE; NITRITES; NITROPRUSSIDE; OXYGEN CONSUMPTION; PULMONARY ARTERY; RATS; THIOCYANATES; VITAMIN B 12;

DROSOPHILA MELANOGASTER; MAMMALIA; MUS;

EID: 34249713678     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: None     Document Type: Article

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