-
1
-
-
77950237717
-
The changed metabolic world with human brown adipose tissue: Therapeutic visions
-
Nedergaard J, Cannon B 2010 The changed metabolic world with human brown adipose tissue: therapeutic visions. Cell Metab 11: 268-272
-
(2010)
Cell Metab
, vol.11
, pp. 268-272
-
-
Nedergaard, J.1
Cannon, B.2
-
2
-
-
0024202118
-
Triiodothyronine amplifies norepinephrine stimulation of uncoupling protein gene transcription by a mechanism not requiring protein synthesis
-
Bianco AC, Sheng XY, Silva JE 1988 Triiodothyronine amplifies norepinephrine stimulation of uncoupling protein gene transcription by a mechanism not requiring protein synthesis. J Biol Chem 263:18168-18175
-
(1988)
J Biol Chem
, vol.263
, pp. 18168-18175
-
-
Bianco, A.C.1
Sheng, X.Y.2
Silva, J.E.3
-
3
-
-
0003162109
-
Role of the thyroid in metabolic responses to a cold environment
-
Sellers EA, You SS 1950 Role of the thyroid in metabolic responses to a cold environment. Am J Physiol 163:81-91
-
(1950)
Am J Physiol
, vol.163
, pp. 81-91
-
-
Sellers, E.A.1
You, S.S.2
-
4
-
-
0023119510
-
Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic function of brown adipose tissue
-
Bianco AC, Silva JE 1987 Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic function of brown adipose tissue. J Clin Invest 79:295-300
-
(1987)
J Clin Invest
, vol.79
, pp. 295-300
-
-
Bianco, A.C.1
Silva, J.E.2
-
5
-
-
57349119069
-
Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling
-
Gereben B, Zavacki AM, Ribich S, Kim BW, Huang SA, Simonides WS, Zeöld A, Bianco AC 2008 Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling. Endocr Rev 29:898-938
-
(2008)
Endocr Rev
, vol.29
, pp. 898-938
-
-
Gereben, B.1
Zavacki, A.M.2
Ribich, S.3
Kim, B.W.4
Huang, S.A.5
Simonides, W.S.6
Zeöld, A.7
Bianco, A.C.8
-
6
-
-
39449088036
-
Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats
-
Simonides WS, Mulcahey MA, Redout EM, Muller A, Zuidwijk MJ, Visser TJ, Wassen FW, Crescenzi A, da-Silva WS, Harney J, Engel FB, Obregon MJ, Larsen PR, Bianco AC, Huang SA 2008 Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats. J Clin Invest 118:975-983
-
(2008)
J Clin Invest
, vol.118
, pp. 975-983
-
-
Simonides, W.S.1
Mulcahey, M.A.2
Redout, E.M.3
Muller, A.4
Zuidwijk, M.J.5
Visser, T.J.6
Wassen, F.W.7
Crescenzi, A.8
Da-Silva, W.S.9
Harney, J.10
Engel, F.B.11
Obregon, M.J.12
Larsen, P.R.13
Bianco, A.C.14
Huang, S.A.15
-
7
-
-
0035211984
-
Targeted disruption of the type 2 selenodeiodinase gene (DIO2) results in a phenotype of pituitary resistance to T4
-
Schneider MJ, Fiering SN, Pallud SE, Parlow AF, St Germain DL, Galton VA 2001 Targeted disruption of the type 2 selenodeiodinase gene (DIO2) results in a phenotype of pituitary resistance to T4. Mol Endocrinol 15:2137-2148
-
(2001)
Mol Endocrinol
, vol.15
, pp. 2137-2148
-
-
Schneider, M.J.1
Fiering, S.N.2
Pallud, S.E.3
Parlow, A.F.4
St Germain, D.L.5
Galton, V.A.6
-
8
-
-
0035185505
-
The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue
-
de Jesus LA, Carvalho SD, Ribeiro MO, Schneider M, Kim SW, Harney JW, Larsen PR, Bianco AC 2001 The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J Clin Invest 108:1379-1385
-
(2001)
J Clin Invest
, vol.108
, pp. 1379-1385
-
-
De Jesus, L.A.1
Carvalho, S.D.2
Ribeiro, M.O.3
Schneider, M.4
Kim, S.W.5
Harney, J.W.6
Larsen, P.R.7
Bianco, A.C.8
-
9
-
-
10744221610
-
Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis
-
Christoffolete MA, Linardi CC, de Jesus L, Ebina KN, Carvalho SD, Ribeiro MO, Rabelo R, Curcio C, Martins L, Kimura ET, Bianco AC 2004 Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis. Diabetes 53:577-584
-
(2004)
Diabetes
, vol.53
, pp. 577-584
-
-
Christoffolete, M.A.1
Linardi, C.C.2
De Jesus, L.3
Ebina, K.N.4
Carvalho, S.D.5
Ribeiro, M.O.6
Rabelo, R.7
Curcio, C.8
Martins, L.9
Kimura, E.T.10
Bianco, A.C.11
-
10
-
-
63849159901
-
A protective role for type 3 deiodinase, a thyroid hormone-inactivating enzyme, in cochlear development and auditory function
-
Ng L, Hernandez A, He W, Ren T, Srinivas M, Ma M, Galton VA, St Germain DL, Forrest D 2009 A protective role for type 3 deiodinase, a thyroid hormone-inactivating enzyme, in cochlear development and auditory function. Endocrinology 150:1952-1960
-
(2009)
Endocrinology
, vol.150
, pp. 1952-1960
-
-
Ng, L.1
Hernandez, A.2
He, W.3
Ren, T.4
Srinivas, M.5
Ma, M.6
Galton, V.A.7
St Germain, D.L.8
Forrest, D.9
-
11
-
-
0036081494
-
Triiodothyronine is required for the stimulation of type II 5′-deiodinase mRNA in rat brown adipocytes
-
Martinez-deMena R, Hernández A, Obregón MJ 2002 Triiodothyronine is required for the stimulation of type II 5′-deiodinase mRNA in rat brown adipocytes. Am J Physiol Endocrinol Metab 282:E1119-E1127
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
-
-
Martinez-deMena, R.1
Hernández, A.2
Obregón, M.J.3
-
12
-
-
31444454037
-
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
-
Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, Sato H, Messaddeq N, Harney JW, Ezaki O, Kodama T, Schoonjans K, Bianco AC, Auwerx J 2006 Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 439: 484-489
-
(2006)
Nature
, vol.439
, pp. 484-489
-
-
Watanabe, M.1
Houten, S.M.2
Mataki, C.3
Christoffolete, M.A.4
Kim, B.W.5
Sato, H.6
Messaddeq, N.7
Harney, J.W.8
Ezaki, O.9
Kodama, T.10
Schoonjans, K.11
Bianco, A.C.12
Auwerx, J.13
-
13
-
-
0025043859
-
Ontogeny and perinatal modulation of gene expression in rat brown adipose tissue. Unaltered iodothyronine 5′-deiodinase activity is necessary for the response to environmental temperature at birth
-
Giralt M, Martin I, Iglesias R, Viñas O, Villarroya F, Mampel T 1990 Ontogeny and perinatal modulation of gene expression in rat brown adipose tissue. Unaltered iodothyronine 5′-deiodinase activity is necessary for the response to environmental temperature at birth. Eur J Biochem 193:297-302
-
(1990)
Eur J Biochem
, vol.193
, pp. 297-302
-
-
Giralt, M.1
Martin, I.2
Iglesias, R.3
Viñas, O.4
Villarroya, F.5
Mampel, T.6
-
14
-
-
0027245963
-
Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation
-
Smas CM, Sul HS 1993 Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation. Cell 73:725-734
-
(1993)
Cell
, vol.73
, pp. 725-734
-
-
Smas, C.M.1
Sul, H.S.2
-
15
-
-
0042856381
-
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12
-
Lin SP, Youngson N, Takada S, Seitz H, Reik W, Paulsen M, Cavaille J, Ferguson-Smith AC 2003 Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet 35:97-102
-
(2003)
Nat Genet
, vol.35
, pp. 97-102
-
-
Lin, S.P.1
Youngson, N.2
Takada, S.3
Seitz, H.4
Reik, W.5
Paulsen, M.6
Cavaille, J.7
Ferguson-Smith, A.C.8
-
16
-
-
34547124567
-
Gene expression from the imprinted Dio3 locus is associated with cell proliferation of cultured brown adipocytes
-
Hernandez A, Garcia B, Obregon MJ 2007 Gene expression from the imprinted Dio3 locus is associated with cell proliferation of cultured brown adipocytes. Endocrinology 148:3968-3976
-
(2007)
Endocrinology
, vol.148
, pp. 3968-3976
-
-
Hernandez, A.1
Garcia, B.2
Obregon, M.J.3
-
17
-
-
33748942837
-
Transcriptional control of adipocyte formation
-
Farmer SR 2006 Transcriptional control of adipocyte formation. Cell Metab 4:263-273
-
(2006)
Cell Metab
, vol.4
, pp. 263-273
-
-
Farmer, S.R.1
-
18
-
-
0041353552
-
Cidea-deficient mice have lean phenotype and are resistant to obesity
-
Zhou Z, Yon Toh S, Chen Z, Guo K, Ng CP, Ponniah S, Lin SC, Hong W, Li P 2003 Cidea-deficient mice have lean phenotype and are resistant to obesity. Nat Genet 35:49-56
-
(2003)
Nat Genet
, vol.35
, pp. 49-56
-
-
Zhou, Z.1
Yon Toh, S.2
Chen, Z.3
Guo, K.4
Ng, C.P.5
Ponniah, S.6
Lin, S.C.7
Hong, W.8
Li, P.9
-
19
-
-
0015719983
-
Thyroid hormone action in cell culture: Domonstration of nuclear receptors in intact cells and isolated nuclei
-
Samuels HH, Tsai JS 1973 Thyroid hormone action in cell culture: domonstration of nuclear receptors in intact cells and isolated nuclei. Proc Natl Acad Sci USA 70:3488-3492
-
(1973)
Proc Natl Acad Sci USA
, vol.70
, pp. 3488-3492
-
-
Samuels, H.H.1
Tsai, J.S.2
-
20
-
-
51049103387
-
Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress
-
Lee YS, Kim AY, Choi JW, Kim M, Yasue S, Son HJ, Masuzaki H, Park KS, Kim JB 2008 Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress. Mol Endocrinol 22:2176-2189
-
(2008)
Mol Endocrinol
, vol.22
, pp. 2176-2189
-
-
Lee, Y.S.1
Kim, A.Y.2
Choi, J.W.3
Kim, M.4
Yasue, S.5
Son, H.J.6
Masuzaki, H.7
Park, K.S.8
Kim, J.B.9
-
21
-
-
47749151115
-
Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage
-
Cabreiro F, Picot CR, Perichon M, Castel J, Friguet B, Petropoulos I 2008 Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage. J Biol Chem 283:16673-16681
-
(2008)
J Biol Chem
, vol.283
, pp. 16673-16681
-
-
Cabreiro, F.1
Picot, C.R.2
Perichon, M.3
Castel, J.4
Friguet, B.5
Petropoulos, I.6
-
22
-
-
33845953689
-
Mitochondrial ROS - Radical detoxification, mediated by protein kinase D
-
DOI 10.1016/j.tcb.2006.11.003, PII S0962892406003254
-
Storz P 2007 Mitochondrial ROS-radical detoxification, mediated by protein kinase D. Trends Cell Biol 17:13-18 (Pubitemid 46028964)
-
(2007)
Trends in Cell Biology
, vol.17
, Issue.1
, pp. 13-18
-
-
Storz, P.1
-
23
-
-
37549018887
-
Synchronized changes in transcript levels of genes activating cold exposure-induced thermogenesis in brown adipose tissue of experimental animals
-
Watanabe M, Yamamoto T, Kakuhata R, Okada N, Kajimoto K, Yamazaki N, Kataoka M, Baba Y, Tamaki T, Shinohara Y 2008 Synchronized changes in transcript levels of genes activating cold exposure-induced thermogenesis in brown adipose tissue of experimental animals. Biochim Biophys Acta 1777:104-112
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 104-112
-
-
Watanabe, M.1
Yamamoto, T.2
Kakuhata, R.3
Okada, N.4
Kajimoto, K.5
Yamazaki, N.6
Kataoka, M.7
Baba, Y.8
Tamaki, T.9
Shinohara, Y.10
-
24
-
-
6344277177
-
Myoglobin: An essential hemoprotein in striated muscle
-
Ordway GA, Garry DJ 2004 Myoglobin: an essential hemoprotein in striated muscle. J Exp Biol 207:3441-3446
-
(2004)
J Exp Biol
, vol.207
, pp. 3441-3446
-
-
Ordway, G.A.1
Garry, D.J.2
-
25
-
-
33645860825
-
Reactive oxygen species have a causal role in multiple forms of insulin resistance
-
Houstis N, Rosen ED, Lander ES 2006 Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 440:944-948
-
(2006)
Nature
, vol.440
, pp. 944-948
-
-
Houstis, N.1
Rosen, E.D.2
Lander, E.S.3
-
26
-
-
33748495984
-
Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress
-
DOI 10.1007/s00125-006-0349-6
-
Bloch-Damti A, Potashnik R, Gual P, Le Marchand-Brustel Y, Tanti JF, Rudich A, Bashan N 2006 Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress. Diabetologia 49:2463-2473 (Pubitemid 44359109)
-
(2006)
Diabetologia
, vol.49
, Issue.10
, pp. 2463-2473
-
-
Bloch-Damti, A.1
Potashnik, R.2
Gual, P.3
Le Marchand-Brustel, Y.4
Tanti, J.F.5
Rudich, A.6
Bashan, N.7
-
27
-
-
0037073679
-
Serine phosphorylation of insulin receptor substrate 1 by inhibitor κ B kinase complex
-
Gao Z, Hwang D, Bataille F, Lefevre M, York D, Quon MJ, Ye J 2002 Serine phosphorylation of insulin receptor substrate 1 by inhibitor κ B kinase complex. J Biol Chem 277:48115-48121
-
(2002)
J Biol Chem
, vol.277
, pp. 48115-48121
-
-
Gao, Z.1
Hwang, D.2
Bataille, F.3
Lefevre, M.4
York, D.5
Quon, M.J.6
Ye, J.7
-
28
-
-
0037077240
-
Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein α
-
Carmona MC, Iglesias R, Obregón MJ, Darlington GJ, Villarroya F, Giralt M 2002 Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein α. J Biol Chem 277:21489-21498
-
(2002)
J Biol Chem
, vol.277
, pp. 21489-21498
-
-
Carmona, M.C.1
Iglesias, R.2
Obregón, M.J.3
Darlington, G.J.4
Villarroya, F.5
Giralt, M.6
-
29
-
-
0033960479
-
Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing
-
Campos-Barros A, Amma LL, Faris JS, Shailam R, Kelley MW, Forrest D 2000 Type 2 iodothyronine deiodinase expression in the cochlea before the onset of hearing. Proc Natl Acad Sci USA 97:1287-1292
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1287-1292
-
-
Campos-Barros, A.1
Amma, L.L.2
Faris, J.S.3
Shailam, R.4
Kelley, M.W.5
Forrest, D.6
-
30
-
-
12144291224
-
Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase
-
Ng L, Goodyear RJ, Woods CA, Schneider MJ, Diamond E, Richardson GP, Kelley MW, Germain DL, Galton VA, Forrest D 2004 Hearing loss and retarded cochlear development in mice lacking type 2 iodothyronine deiodinase. Proc Natl Acad Sci USA 101:3474-3479
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3474-3479
-
-
Ng, L.1
Goodyear, R.J.2
Woods, C.A.3
Schneider, M.J.4
Diamond, E.5
Richardson, G.P.6
Kelley, M.W.7
Germain, D.L.8
Galton, V.A.9
Forrest, D.10
-
31
-
-
77950245008
-
Transcriptional control of brown fat development
-
Kajimura S, Seale P, Spiegelman BM 2010 Transcriptional control of brown fat development. Cell Metab 11:257-262
-
(2010)
Cell Metab
, vol.11
, pp. 257-262
-
-
Kajimura, S.1
Seale, P.2
Spiegelman, B.M.3
-
32
-
-
33947222099
-
Impaired adipogenesis caused by a mutated thyroid hormone α1 receptor
-
DOI 10.1128/MCB.02189-06
-
Ying H, Araki O, Furuya F, Kato Y, Cheng SY 2007 Impaired adipogenesis caused by a mutated thyroid hormone α1 receptor. Mol Cell Biol 27:2359-2371 (Pubitemid 46418487)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.6
, pp. 2359-2371
-
-
Ying, H.1
Araki, O.2
Furuya, F.3
Kato, Y.4
Cheng, S.-Y.5
-
33
-
-
0024498549
-
Coupling growth arrest and adipocyte differentiation
-
Ailhaud G, Dani C, Amri EZ, Djian P, Vannier C, Doglio A, Forest C, Gaillard D, Négrel R, Grimaldi P 1989 Coupling growth arrest and adipocyte differentiation. Environ Health Perspect 80:17-23
-
(1989)
Environ Health Perspect
, vol.80
, pp. 17-23
-
-
Ailhaud, G.1
Dani, C.2
Amri, E.Z.3
Djian, P.4
Vannier, C.5
Doglio, A.6
Forest, C.7
Gaillard, D.8
Négrel, R.9
Grimaldi, P.10
-
34
-
-
0038587678
-
PPARγ coactivator-1α expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations
-
Irrcher I, Adhihetty PJ, Sheehan T, Joseph AM, Hood DA 2003 PPARγ coactivator-1α expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations. Am J Physiol Cell Physiol 284:C1669-C1677
-
(2003)
Am J Physiol Cell Physiol
, vol.284
-
-
Irrcher, I.1
Adhihetty, P.J.2
Sheehan, T.3
Joseph, A.M.4
Hood, D.A.5
-
35
-
-
0035945237
-
Two thyroid hormone-mediated gene expression patterns in vivo identified by cDNA expression arrays in rat
-
Weitzel JM, Radtke C, Seitz HJ 2001 Two thyroid hormone-mediated gene expression patterns in vivo identified by cDNA expression arrays in rat. Nucleic Acids Res 29:5148-5155
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 5148-5155
-
-
Weitzel, J.M.1
Radtke, C.2
Seitz, H.J.3
-
36
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
DOI 10.1016/S0092-8674(00)81410-5
-
Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM 1998 A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92:829-839 (Pubitemid 28155321)
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
37
-
-
33646124709
-
Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation
-
Uldry M, Yang W, St-Pierre J, Lin J, Seale P, Spiegelman BM 2006 Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation. Cell Metab 3:333-341
-
(2006)
Cell Metab
, vol.3
, pp. 333-341
-
-
Uldry, M.1
Yang, W.2
St-Pierre, J.3
Lin, J.4
Seale, P.5
Spiegelman, B.M.6
-
38
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jäger S, Handschin C, Zheng K, Lin J, Yang W, Simon DK, Bachoo R, Spiegelman BM 2006 Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127:397-408
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jäger, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
Simon, D.K.11
Bachoo, R.12
Spiegelman, B.M.13
|