메뉴 건너뛰기




Volumn 21, Issue 5-6, 2010, Pages 394-408

Role of the glucose-dependent insulinotropic polypeptide and its receptor in the central nervous system: Therapeutic potential in neurological diseases

Author keywords

Alzheimer's disease; animal models; central nervous system; GIP receptor; glucose dependent insulinotropic polypeptide; mesial temporal lobe epilepsy related to hippocampal sclerosis; neurological diseases; neuroplasticity; Parkinson's disease

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE; INCRETIN;

EID: 77955982823     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e32833c8544     Document Type: Review
Times cited : (49)

References (131)
  • 1
    • 0029819081 scopus 로고    scopus 로고
    • Amyloid beta toxicity consists of a Ca(2+)-independent early phase and a Ca(2+)-dependent late phase
    • Abe K, Kimura H (1996). Amyloid beta toxicity consists of a Ca(2+)-independent early phase and a Ca(2+)-dependent late phase. J Neurochem 67: 2074-2078.
    • (1996) J Neurochem , vol.67 , pp. 2074-2078
    • Abe, K.1    Kimura, H.2
  • 2
    • 0035353725 scopus 로고    scopus 로고
    • Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature
    • Ahlskog JE, Muenter MD (2001). Frequency of levodopa-related dyskinesias and motor fluctuations as estimated from the cumulative literature. Mov Disord 16:448-458.
    • (2001) Mov Disord , vol.16 , pp. 448-458
    • Ahlskog, J.E.1    Muenter, M.D.2
  • 3
    • 37149050857 scopus 로고    scopus 로고
    • Disease-modifying drugs and Parkinson's disease
    • Allain H, Bentue-Ferrer D, Akwa Y (2008). Disease-modifying drugs and Parkinson's disease. Prog Neurobiol 84:25-39.
    • (2008) Prog Neurobiol , vol.84 , pp. 25-39
    • Allain, H.1    Bentue-Ferrer, D.2    Akwa, Y.3
  • 4
    • 2442587216 scopus 로고    scopus 로고
    • Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's disease: Linkage of poorer cognitive performance to tau pathology in forebrain
    • Arendash GW, Lewis J, Leighty RE, McGowan E, Cracchiolo JR, Hutton M, et al. (2004). Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's disease: linkage of poorer cognitive performance to tau pathology in forebrain. Brain Res 1012:29-41.
    • (2004) Brain Res , vol.1012 , pp. 29-41
    • Arendash, G.W.1    Lewis, J.2    Leighty, R.E.3    McGowan, E.4    Cracchiolo, J.R.5    Hutton, M.6
  • 5
    • 0038475776 scopus 로고    scopus 로고
    • Prediction of transition from cognitive impairment to senile dementia: A prospective, longitudinal study
    • Artero S, Tierney MC, Touchon J, Ritchie K (2003). Prediction of transition from cognitive impairment to senile dementia: a prospective, longitudinal study. Acta Psychiatr Scand 107:390-393.
    • (2003) Acta Psychiatr Scand , vol.107 , pp. 390-393
    • Artero, S.1    Tierney, M.C.2    Touchon, J.3    Ritchie, K.4
  • 6
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • Baggio LL, Drucker DJ (2007). Biology of incretins: GLP-1 and GIP. Gastroenterology 132:2131-2157.
    • (2007) Gastroenterology , vol.132 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 7
    • 23844525681 scopus 로고    scopus 로고
    • The Sp transcription factors are involved in the cellular expression of the human glucose-dependent insulinotropic polypeptide receptor gene and overexpressed in adrenals of patients with Cushing's syndrome
    • Baldacchino V, Oble S, Decarie PO, Bourdeau I, Hamet P, Tremblay J, et al. (2005). The Sp transcription factors are involved in the cellular expression of the human glucose-dependent insulinotropic polypeptide receptor gene and overexpressed in adrenals of patients with Cushing's syndrome. J Mol Endocrinol 35:61-71.
    • (2005) J Mol Endocrinol , vol.35 , pp. 61-71
    • Baldacchino, V.1    Oble, S.2    Decarie, P.O.3    Bourdeau, I.4    Hamet, P.5    Tremblay, J.6
  • 8
    • 0020596734 scopus 로고
    • Hamster preproglucagon contains the sequence of glucagon and two related peptides
    • Bell GI, Santerre RF, Mullenbach GT (1983). Hamster preproglucagon contains the sequence of glucagon and two related peptides. Nature 302:716-718.
    • (1983) Nature , vol.302 , pp. 716-718
    • Bell, G.I.1    Santerre, R.F.2    Mullenbach, G.T.3
  • 9
    • 38849196303 scopus 로고    scopus 로고
    • Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease
    • Bertilsson G, Patrone C, Zachrisson O, Andersson A, Dannaeus K, Heidrich J, et al. (2008). Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease. J Neurosci Res 86:326-338.
    • (2008) J Neurosci Res , vol.86 , pp. 326-338
    • Bertilsson, G.1    Patrone, C.2    Zachrisson, O.3    Andersson, A.4    Dannaeus, K.5    Heidrich, J.6
  • 11
    • 17744374566 scopus 로고    scopus 로고
    • Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors
    • Bollag RJ, Zhong Q, Phillips P, Min L, Zhong L, Cameron R, et al. (2000). Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors. Endocrinology 141:1228-1235.
    • (2000) Endocrinology , vol.141 , pp. 1228-1235
    • Bollag, R.J.1    Zhong, Q.2    Phillips, P.3    Min, L.4    Zhong, L.5    Cameron, R.6
  • 12
    • 0034087454 scopus 로고    scopus 로고
    • Changes in synaptosomal ectonucleotidase activities in two rat models of temporal lobe epilepsy
    • Bonan CD, Walz R, Pereira GS, Worm PV, Battastini AM, Cavalheiro EA, et al. (2000). Changes in synaptosomal ectonucleotidase activities in two rat models of temporal lobe epilepsy. Epilepsy Res 39:229-238.
    • (2000) Epilepsy Res , vol.39 , pp. 229-238
    • Bonan, C.D.1    Walz, R.2    Pereira, G.S.3    Worm, P.V.4    Battastini, A.M.5    Cavalheiro, E.A.6
  • 14
    • 0030814103 scopus 로고    scopus 로고
    • Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene in a mouse neuroendocrine tumor cell line
    • Boylan MO, Jepeal LI, Jarboe LA, Wolfe MM (1997). Cell-specific expression of the glucose-dependent insulinotropic polypeptide gene in a mouse neuroendocrine tumor cell line. J Biol Chem 272:17438-17443.
    • (1997) J Biol Chem , vol.272 , pp. 17438-17443
    • Boylan, M.O.1    Jepeal, L.I.2    Jarboe, L.A.3    Wolfe, M.M.4
  • 17
    • 0018193765 scopus 로고
    • Electronimmu-nocytochemical evidence for the K cell localization of gastric inhibitory polypeptide (GIP) in man
    • Buchan AM, Polak JM, Capella C, Solcia E, Pearse AG (1978). Electronimmu-nocytochemical evidence for the K cell localization of gastric inhibitory polypeptide (GIP) in man. Histochemistry 56:37-44.
    • (1978) Histochemistry , vol.56 , pp. 37-44
    • Buchan, A.M.1    Polak, J.M.2    Capella, C.3    Solcia, E.4    Pearse, A.G.5
  • 18
    • 66049137664 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): Cellular localization, lesion-affected expression, and impaired regenerative axonal growth
    • Buhren BA, Gasis M, Thorens B, Muller HW, Bosse F (2009). Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth. J Neurosci Res 87:1858-1870.
    • (2009) J Neurosci Res , vol.87 , pp. 1858-1870
    • Buhren, B.A.1    Gasis, M.2    Thorens, B.3    Muller, H.W.4    Bosse, F.5
  • 19
    • 0026340904 scopus 로고
    • Long-term effects of pilocarpine in rats: Structural damage of the brain triggers kindling and spontaneous recurrent seizures
    • Cavalheiro EA, Leite JP, Bortolotto ZA, Turski WA, Ikonomidou C, Turski L (1991). Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures. Epilepsia 32: 778-782.
    • (1991) Epilepsia , vol.32 , pp. 778-782
    • Cavalheiro, E.A.1    Leite, J.P.2    Bortolotto, Z.A.3    Turski, W.A.4    Ikonomidou, C.5    Turski, L.6
  • 20
    • 65049088695 scopus 로고    scopus 로고
    • Cell migration in the normal and pathological postnatal mammalian brain
    • Cayre M, Canoll P, Goldman JE (2009). Cell migration in the normal and pathological postnatal mammalian brain. Prog Neurobiol 88:41-63.
    • (2009) Prog Neurobiol , vol.88 , pp. 41-63
    • Cayre, M.1    Canoll, P.2    Goldman, J.E.3
  • 21
    • 32544432029 scopus 로고    scopus 로고
    • Non-motor symptoms of Parkinson's disease: Diagnosis and management
    • Chaudhuri KR, Healy DG, Schapira AH (2006). Non-motor symptoms of Parkinson's disease: diagnosis and management. Lancet Neurol 5:235-245.
    • (2006) Lancet Neurol , vol.5 , pp. 235-245
    • Chaudhuri, K.R.1    Healy, D.G.2    Schapira, A.H.3
  • 22
    • 0029912056 scopus 로고    scopus 로고
    • Mechanisms of neuronal death in Alzheimer's disease
    • Cotman CW, Su JH (1996). Mechanisms of neuronal death in Alzheimer's disease. Brain Pathol 6:493-506.
    • (1996) Brain Pathol , vol.6 , pp. 493-506
    • Cotman, C.W.1    Su, J.H.2
  • 23
    • 0036602967 scopus 로고    scopus 로고
    • Exercise: A behavioral intervention to enhance brain health and plasticity
    • Cotman CW, Berchtold NC (2002). Exercise: a behavioral intervention to enhance brain health and plasticity. Trends Neurosci 25:295-301.
    • (2002) Trends Neurosci , vol.25 , pp. 295-301
    • Cotman, C.W.1    Berchtold, N.C.2
  • 24
    • 1242316296 scopus 로고    scopus 로고
    • Insulin and neurodegenerative disease: Shared and specific mechanisms
    • Craft S, Watson GS (2004). Insulin and neurodegenerative disease: shared and specific mechanisms. Lancet Neurol 3:169-178.
    • (2004) Lancet Neurol , vol.3 , pp. 169-178
    • Craft, S.1    Watson, G.S.2
  • 25
    • 0018758893 scopus 로고
    • The incretin concept today
    • Creutzfeldt W (1979). The incretin concept today. Diabetologia 16:75-85.
    • (1979) Diabetologia , vol.16 , pp. 75-85
    • Creutzfeldt, W.1
  • 26
    • 0034703590 scopus 로고    scopus 로고
    • Lipid peroxidation in hippocampus early and late after status epilepticus induced by pilocarpine or kainic acid in Wistar rats
    • Dal-Pizzol F, Klamt F, Vianna MM, Schroder N, Quevedo J, Benfato MS, et al. (2000). Lipid peroxidation in hippocampus early and late after status epilepticus induced by pilocarpine or kainic acid in Wistar rats. Neurosci Lett 291:179-182.
    • (2000) Neurosci Lett , vol.291 , pp. 179-182
    • Dal-Pizzol, F.1    Klamt, F.2    Vianna, M.M.3    Schroder, N.4    Quevedo, J.5    Benfato, M.S.6
  • 27
    • 0027529491 scopus 로고
    • Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): Cleavage of APP occurs in a late compartment of the default secretion pathway
    • De Strooper B, Umans L, Van Leuven F, Van Den Berghe H (1993). Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway. J Cell Biol 121:295-304.
    • (1993) J Cell Biol , vol.121 , pp. 295-304
    • De Strooper, B.1    Umans, L.2    Van Leuven, F.3    Van Den Berghe, H.4
  • 29
    • 0030979469 scopus 로고    scopus 로고
    • Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain
    • Doetsch F, Garcia-Verdugo JM, Alvarez-Buylla A (1997). Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J Neurosci 17:5046-5061.
    • (1997) J Neurosci , vol.17 , pp. 5046-5061
    • Doetsch, F.1    Garcia-Verdugo, J.M.2    Alvarez-Buylla, A.3
  • 30
    • 39049153943 scopus 로고    scopus 로고
    • The olfactory vector hypothesis of neurodegenerative disease: Is it viable?
    • Doty RL (2008). The olfactory vector hypothesis of neurodegenerative disease: is it viable? Ann Neurol 63:7-15.
    • (2008) Ann Neurol , vol.63 , pp. 7-15
    • Doty, R.L.1
  • 31
    • 0141785429 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase
    • Ehses JA, Casilla VR, Doty T, Pospisilik JA, Winter KD, Demuth HU, et al. (2003). Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase. Endocrinology 144:4433-4445.
    • (2003) Endocrinology , vol.144 , pp. 4433-4445
    • Ehses, J.A.1    Casilla, V.R.2    Doty, T.3    Pospisilik, J.A.4    Winter, K.D.5    Demuth, H.U.6
  • 32
    • 0030030960 scopus 로고    scopus 로고
    • Surgery for seizures
    • Engel J Jr (1996). Surgery for seizures. N Engl J Med 334:647-652.
    • (1996) N Engl J Med , vol.334 , pp. 647-652
    • Engel Jr., J.1
  • 34
    • 49649085125 scopus 로고    scopus 로고
    • Dorothy Hodgkin Lecture 2008, Gastric inhibitory polypeptide (GIP) revisited: A new therapeutic target for obesity-diabetes?
    • Flatt PR (2008). Dorothy Hodgkin Lecture 2008. Gastric inhibitory polypeptide (GIP) revisited: a new therapeutic target for obesity-diabetes? Diabet Med 25:759-764.
    • (2008) Diabet Med , vol.25 , pp. 759-764
    • Flatt, P.R.1
  • 35
    • 0026353502 scopus 로고
    • Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease
    • Flood JF, Morley JE, Roberts E (1991). Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease. Proc Natl Acad Sci\USA 88:3363-3366.
    • (1991) Proc Natl Acad Sci\USA , vol.88 , pp. 3363-3366
    • Flood, J.F.1    Morley, J.E.2    Roberts, E.3
  • 36
    • 34147171111 scopus 로고    scopus 로고
    • Antioxidant responses and lipid peroxidation following intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats: Increased susceptibility of olfactory bulb
    • Franco J, Prediger RD, Pandolfo P, Takahashi RN, Farina M, Dafre AL (2007). Antioxidant responses and lipid peroxidation following intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats: increased susceptibility of olfactory bulb. Life Sci 80:1906-1914.
    • (2007) Life Sci , vol.80 , pp. 1906-1914
    • Franco, J.1    Prediger, R.D.2    Pandolfo, P.3    Takahashi, R.N.4    Farina, M.5    Dafre, A.L.6
  • 37
    • 0035128734 scopus 로고    scopus 로고
    • Blockade of long-term potentiation by beta-amyloid peptides in the CA1 region of the rat hippocampus in vivo
    • Freir DB, Holscher C, Herron CE (2001). Blockade of long-term potentiation by beta-amyloid peptides in the CA1 region of the rat hippocampus in vivo. J Neurophysiol 85:708-713.
    • (2001) J Neurophysiol , vol.85 , pp. 708-713
    • Freir, D.B.1    Holscher, C.2    Herron, C.E.3
  • 38
    • 77951675095 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion
    • Fujita Y, Wideman RD, Asadi A, Yang GK, Baker R, Webber T, et al. (2010). Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion. Gastroenterology 138:1966-1975.
    • (2010) Gastroenterology , vol.138 , pp. 1966-1975
    • Fujita, Y.1    Wideman, R.D.2    Asadi, A.3    Yang, G.K.4    Baker, R.5    Webber, T.6
  • 39
    • 0034712047 scopus 로고    scopus 로고
    • Mammalian neural stem cells
    • Gage FH (2000). Mammalian neural stem cells. Science 287:1433-1438.
    • (2000) Science , vol.287 , pp. 1433-1438
    • Gage, F.H.1
  • 40
    • 44149122563 scopus 로고    scopus 로고
    • GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
    • Gault VA, Holscher C (2008a). GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid. Eur J Pharmacol 587:112-117.
    • (2008) Eur J Pharmacol , vol.587 , pp. 112-117
    • Gault, V.A.1    Holscher, C.2
  • 41
    • 42249106405 scopus 로고    scopus 로고
    • Protease-resistant glucose-dependent insulino-tropic polypeptide agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
    • Gault VA, Holscher C (2008b). Protease-resistant glucose-dependent insulino-tropic polypeptide agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid. J Neurophysiol 99:1590-1595.
    • (2008) J Neurophysiol , vol.99 , pp. 1590-1595
    • Gault, V.A.1    Holscher, C.2
  • 42
    • 34249024370 scopus 로고    scopus 로고
    • Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25-35) are dependent on stimulation-protocol and genetic background
    • Gengler S, Gault VA, Harriott P, Holscher C (2007). Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid (25-35) are dependent on stimulation-protocol and genetic background. Exp Brain Res 179:621-630.
    • (2007) Exp Brain Res , vol.179 , pp. 621-630
    • Gengler, S.1    Gault, V.A.2    Harriott, P.3    Holscher, C.4
  • 43
    • 0345305844 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons
    • Gilman CP, Perry T, Furukawa K, Grieg NH, Egan JM, Mattson MP (2003). Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons. J Neurochem 87: 1137-1144.
    • (2003) J Neurochem , vol.87 , pp. 1137-1144
    • Gilman, C.P.1    Perry, T.2    Furukawa, K.3    Grieg, N.H.4    Egan, J.M.5    Mattson, M.P.6
  • 44
    • 57149083860 scopus 로고    scopus 로고
    • The incretins: From the concept to their use in the treatment of type 2 diabetes, Part A: Incretins: concept and physiological functions
    • Girard J (2008). The incretins: from the concept to their use in the treatment of type 2 diabetes. Part A: incretins: concept and physiological functions. Diabetes Metab 34:550-559.
    • (2008) Diabetes Metab , vol.34 , pp. 550-559
    • Girard, J.1
  • 45
    • 0034333018 scopus 로고    scopus 로고
    • Cognition and synaptic plasticity in diabetes mellitus
    • Gispen WH, Biessels GJ (2000). Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 23:542-549.
    • (2000) Trends Neurosci , vol.23 , pp. 542-549
    • Gispen, W.H.1    Biessels, G.J.2
  • 46
    • 0031843721 scopus 로고    scopus 로고
    • The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living
    • Gorell JM, Johnson CC, Rybicki BA, Peterson EL, Richardson RJ (1998). The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living. Neurology 50:1346-1350.
    • (1998) Neurology , vol.50 , pp. 1346-1350
    • Gorell, J.M.1    Johnson, C.C.2    Rybicki, B.A.3    Peterson, E.L.4    Richardson, R.J.5
  • 47
    • 0029077296 scopus 로고
    • Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor
    • Gremlich S, Porret A, Hani EH, Cherif D, Vionnet N, Froguel P, et al. (1995). Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor. Diabetes 44:1202-1208.
    • (1995) Diabetes , vol.44 , pp. 1202-1208
    • Gremlich, S.1    Porret, A.2    Hani, E.H.3    Cherif, D.4    Vionnet, N.5    Froguel, P.6
  • 48
    • 0033615580 scopus 로고    scopus 로고
    • The presenilins in Alzheimer's disease-proteolysis holds the key
    • Haass C, De Strooper B (1999). The presenilins in Alzheimer's disease-proteolysis holds the key. Science 286:916-919.
    • (1999) Science , vol.286 , pp. 916-919
    • Haass, C.1    De Strooper, B.2
  • 49
    • 0037175342 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating peptide in the rat central nervous system: An immunohistochemical and in situ hybridization study
    • Hannibal J (2002). Pituitary adenylate cyclase-activating peptide in the rat central nervous system: an immunohistochemical and in situ hybridization study. J Comp Neurol 453:389-417.
    • (2002) J Comp Neurol , vol.453 , pp. 389-417
    • Hannibal, J.1
  • 50
    • 45549108268 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease
    • Harkavyi A, Abuirmeileh A, Lever R, Kingsbury AE, Biggs CS, Whitton PS (2008). Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease. J Neuroinflammation 5:19.
    • (2008) J Neuroinflammation , vol.5 , pp. 19
    • Harkavyi, A.1    Abuirmeileh, A.2    Lever, R.3    Kingsbury, A.E.4    Biggs, C.S.5    Whitton, P.S.6
  • 51
    • 7244253060 scopus 로고    scopus 로고
    • Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: Modulation by zinc
    • Harris FM, Brecht WJ, Xu Q, Mahley RW, Huang Y (2004). Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: modulation by zinc. J Biol Chem 279:44795-44801.
    • (2004) J Biol Chem , vol.279 , pp. 44795-44801
    • Harris, F.M.1    Brecht, W.J.2    Xu, Q.3    Mahley, R.W.4    Huang, Y.5
  • 53
    • 0023740954 scopus 로고
    • Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease
    • Hirsch E, Graybiel AM, Agid YA (1988). Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature 334:345-348.
    • (1988) Nature , vol.334 , pp. 345-348
    • Hirsch, E.1    Graybiel, A.M.2    Agid, Y.A.3
  • 54
    • 77954953382 scopus 로고    scopus 로고
    • New roles for insulin-like hormones in neuronal signalling and protection: New hopes for novel treatments of Alzheimer's disease?
    • press doi:10.1016/j.neurobiolaging.2008.08.023
    • Holscher C, Li L. New roles for insulin-like hormones in neuronal signalling and protection: new hopes for novel treatments of Alzheimer's disease? Neurobiol Aging (in press). doi:10.1016/j.neurobiolaging.2008.08.023.
    • Neurobiol Aging
    • Holscher, C.1    Li, L.2
  • 55
    • 33947262557 scopus 로고    scopus 로고
    • Soluble beta-amyloid reversibly impairs hippocampal synaptic plasticity and spatial learning
    • Holscher C, Gengler S, Gault VA, Harriott P, Mallot HA (2007). Soluble beta-amyloid reversibly impairs hippocampal synaptic plasticity and spatial learning. Eur J Pharmacol 561:85-90.
    • (2007) Eur J Pharmacol , vol.561 , pp. 85-90
    • Holscher, C.1    Gengler, S.2    Gault, V.A.3    Harriott, P.4    Mallot, H.A.5
  • 56
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
    • Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, et al. (1996). Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274:99-102.
    • (1996) Science , vol.274 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3    Eckman, C.4    Harigaya, Y.5    Younkin, S.6
  • 57
    • 67349171365 scopus 로고    scopus 로고
    • Molecular evolution of mammalian incretin hormone genes
    • Irwin DM (2009). Molecular evolution of mammalian incretin hormone genes. Regul Pept 155:121-130.
    • (2009) Regul Pept , vol.155 , pp. 121-130
    • Irwin, D.M.1
  • 58
    • 0031019320 scopus 로고    scopus 로고
    • Beta-amyloid peptide-induced morphological changes coincide with increased K + and Cl-channel activity in rat cortical astrocytes
    • Jalonen TO, Charniga CJ, Wielt DB (1997). Beta-amyloid peptide-induced morphological changes coincide with increased K + and Cl-channel activity in rat cortical astrocytes. Brain Res 746:85-97.
    • (1997) Brain Res , vol.746 , pp. 85-97
    • Jalonen, T.O.1    Charniga, C.J.2    Wielt, D.B.3
  • 59
    • 43549103295 scopus 로고    scopus 로고
    • GATA-4 upregulates glucose-dependent insulinotropic polypeptide expression in cells of pancreatic and intestinal lineage
    • Jepeal LI, Boylan MO, Michael Wolfe M (2008). GATA-4 upregulates glucose-dependent insulinotropic polypeptide expression in cells of pancreatic and intestinal lineage. Mol Cell Endocrinol 287:20-29.
    • (2008) Mol Cell Endocrinol , vol.287 , pp. 20-29
    • Jepeal, L.I.1    Boylan, M.O.2    Michael Wolfe, M.3
  • 60
    • 4444304016 scopus 로고    scopus 로고
    • Beta-amyloid (1-42)-induced learning and memory deficits in mice: Involvement of oxidative burdens in the hippocampus and cerebral cortex
    • Jhoo JH, Kim HC, Nabeshima T, Yamada K, Shin EJ, Jhoo WK, et al. (2004). Beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex. Behav Brain Res 155:185-196.
    • (2004) Behav Brain Res , vol.155 , pp. 185-196
    • Jhoo, J.H.1    Kim, H.C.2    Nabeshima, T.3    Yamada, K.4    Shin, E.J.5    Jhoo, W.K.6
  • 61
    • 0023950336 scopus 로고
    • Distribution of glucagonlike peptide i (GLP-I), glucagon, and glicentin in the rat brain: An immunocytochemical study
    • Jin SL, Han VK, Simmons JG, Towle AC, Lauder JM, Lund PK (1988). Distribution of glucagonlike peptide I (GLP-I), glucagon, and glicentin in the rat brain: an immunocytochemical study. J Comp Neurol 271:519-532.
    • (1988) J Comp Neurol , vol.271 , pp. 519-532
    • Jin, S.L.1    Han, V.K.2    Simmons, J.G.3    Towle, A.C.4    Lauder, J.M.5    Lund, P.K.6
  • 62
    • 20444491588 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression
    • Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CH (2005). Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression. J Biol Chem 280: 22297-22307.
    • (2005) J Biol Chem , vol.280 , pp. 22297-22307
    • Kim, S.J.1    Winter, K.2    Nian, C.3    Tsuneoka, M.4    Koda, Y.5    McIntosh, C.H.6
  • 63
    • 23644459835 scopus 로고    scopus 로고
    • Molecular mechanisms initiating amyloid beta-fibril formation in Alzheimer's disease
    • Kirkitadze MD, Kowalska A (2005). Molecular mechanisms initiating amyloid beta-fibril formation in Alzheimer's disease. Acta Biochim Pol 52:417-423.
    • (2005) Acta Biochim Pol , vol.52 , pp. 417-423
    • Kirkitadze, M.D.1    Kowalska, A.2
  • 64
    • 0031560912 scopus 로고    scopus 로고
    • Gastric inhibitory polypeptide activates MAP kinase through the wortmannin-sensitive and-insensitive pathways
    • Kubota A, Yamada Y, Yasuda K, Someya Y, Ihara Y, Kagimoto S, et al. (1997). Gastric inhibitory polypeptide activates MAP kinase through the wortmannin-sensitive and-insensitive pathways. Biochem Biophys Res Commun 235:171-175.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 171-175
    • Kubota, A.1    Yamada, Y.2    Yasuda, K.3    Someya, Y.4    Ihara, Y.5    Kagimoto, S.6
  • 65
    • 0001101009 scopus 로고
    • Studies on the physiology of secretin
    • LaBarre J, Still EV (1930). Studies on the physiology of secretin. Am J Physiol 91:649-653.
    • (1930) Am J Physiol , vol.91 , pp. 649-653
    • Labarre, J.1    Still, E.V.2
  • 66
    • 0142215382 scopus 로고    scopus 로고
    • Homogeneity and heterogeneity in mild cognitive impairment and Alzheimer's disease: A cross-sectional and longitudinal study of 55 cases
    • Lambon Ralph MA, Patterson K, Graham N, Dawson K, Hodges JR (2003). Homogeneity and heterogeneity in mild cognitive impairment and Alzheimer's disease: a cross-sectional and longitudinal study of 55 cases. Brain 126:2350-2362.
    • (2003) Brain , vol.126 , pp. 2350-2362
    • Lambon Ralph, M.A.1    Patterson, K.2    Graham, N.3    Dawson, K.4    Hodges, J.R.5
  • 67
    • 62349111236 scopus 로고    scopus 로고
    • Regulation of aldosterone secretion by several aberrant receptors including for glucose-dependent insulinotropic peptide in a patient with an aldoster-onoma
    • Lampron A, Bourdeau I, Oble S, Godbout A, Schurch W, Arjane P, et al. (2009). Regulation of aldosterone secretion by several aberrant receptors including for glucose-dependent insulinotropic peptide in a patient with an aldoster-onoma. J Clin Endocrinol Metab 94:750-756.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 750-756
    • Lampron, A.1    Bourdeau, I.2    Oble, S.3    Godbout, A.4    Schurch, W.5    Arjane, P.6
  • 69
    • 33846195875 scopus 로고    scopus 로고
    • Apoptosis in the pathophysiology of diabetes mellitus
    • Lee SC, Pervaiz S (2007). Apoptosis in the pathophysiology of diabetes mellitus. Int J Biochem Cell Biol 39:497-504.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 497-504
    • Lee, S.C.1    Pervaiz, S.2
  • 70
    • 36448936053 scopus 로고    scopus 로고
    • Common pathological processes in Alzheimer disease and type 2 diabetes: A review
    • Li L, Holscher C (2007). Common pathological processes in Alzheimer disease and type 2 diabetes: a review. Brain Res Rev 56:384-402.
    • (2007) Brain Res Rev , vol.56 , pp. 384-402
    • Li, L.1    Holscher, C.2
  • 71
    • 0037414781 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis
    • Li Y, Hansotia T, Yusta B, Ris F, Halban PA, Drucker DJ (2003). Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis. J Biol Chem 278:471-478.
    • (2003) J Biol Chem , vol.278 , pp. 471-478
    • Li, Y.1    Hansotia, T.2    Yusta, B.3    Ris, F.4    Halban, P.A.5    Drucker, D.J.6
  • 72
    • 0028361594 scopus 로고
    • Long-distance neuronal migration in the adult mammalian brain
    • Lois C, Alvarez-Buylla A (1994). Long-distance neuronal migration in the adult mammalian brain. Science 264:1145-1148.
    • (1994) Science , vol.264 , pp. 1145-1148
    • Lois, C.1    Alvarez-Buylla, A.2
  • 73
    • 0027393644 scopus 로고
    • The role of the free cytosolic calcium level in beta-cell signal transduction by gastric inhibitory polypeptide and glucagon-like peptide I(7-37
    • Lu M, Wheeler MB, Leng XH, Boyd AE III (1993). The role of the free cytosolic calcium level in beta-cell signal transduction by gastric inhibitory polypeptide and glucagon-like peptide I(7-37). Endocrinology 132:94-100.
    • (1993) Endocrinology , vol.132 , pp. 94-100
    • Lu, M.1    Wheeler, M.B.2    Leng, X.H.3    Boyd Iii, A.E.4
  • 74
    • 0027291286 scopus 로고
    • Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone
    • Luskin MB (1993). Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone. Neuron 11:173-189.
    • (1993) Neuron , vol.11 , pp. 173-189
    • Luskin, M.B.1
  • 75
    • 0037268159 scopus 로고    scopus 로고
    • A novel pathway for regulation of glucose-dependent insulinotropic polypep-tide (GIP) receptor expression in beta cells
    • Lynn FC, Thompson SA, Pospisilik JA, Ehses JA, Hinke SA, Pamir N, et al. (2003). A novel pathway for regulation of glucose-dependent insulinotropic polypep-tide (GIP) receptor expression in beta cells. FASEB J 17:91-93.
    • (2003) FASEB J , vol.17 , pp. 91-93
    • Lynn, F.C.1    Thompson, S.A.2    Pospisilik, J.A.3    Ehses, J.A.4    Hinke, S.A.5    Pamir, N.6
  • 76
    • 0027276524 scopus 로고
    • Effects of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) on the spontaneous release of acetylcholine from the rat hippocampus by brain microdialysis
    • Masuo Y, Matsumoto Y,Tokito F,Tsuda M, Fujino M (1993a). Effects of vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) on the spontaneous release of acetylcholine from the rat hippocampus by brain microdialysis. Brain Res 611:207-215.
    • (1993) Brain Res , vol.611 , pp. 207-215
    • Masuo, Y.1    Matsumoto, Y.2    Tokito, F.3    Tsuda, M.4    Fujino, M.5
  • 77
    • 0027476845 scopus 로고
    • Regional distribution of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat central nervous system as determined by sandwich-enzyme immunoassay
    • Masuo Y, Suzuki N, Matsumoto H, Tokito F, Matsumoto Y, Tsuda M, et al. (1993b). Regional distribution of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat central nervous system as determined by sandwich-enzyme immunoassay. Brain Res 602:57-63.
    • (1993) Brain Res , vol.602 , pp. 57-63
    • Masuo, Y.1    Suzuki, N.2    Matsumoto, H.3    Tokito, F.4    Matsumoto, Y.5    Tsuda, M.6
  • 78
    • 0034329742 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disorders
    • Mattson MP (2000). Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol 1:120-129.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 120-129
    • Mattson, M.P.1
  • 79
    • 30944431530 scopus 로고    scopus 로고
    • Ectopic expression of the gastric inhibitory polypeptide receptor gene is a sufficient genetic event to induce benign adrenocortical tumor in a xenotransplantation model
    • Mazzuco TL, Chabre O, Sturm N, Feige JJ, Thomas M (2006). Ectopic expression of the gastric inhibitory polypeptide receptor gene is a sufficient genetic event to induce benign adrenocortical tumor in a xenotransplantation model. Endocrinology 147:782-790.
    • (2006) Endocrinology , vol.147 , pp. 782-790
    • Mazzuco, T.L.1    Chabre, O.2    Sturm, N.3    Feige, J.J.4    Thomas, M.5
  • 81
    • 34249027009 scopus 로고    scopus 로고
    • Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: Relevance for the behavioral and synaptic deficits induced by amyloid beta protein
    • Medeiros R, Prediger RD, Passos GF, Pandolfo P, Duarte FS, Franco JL, et al. (2007). Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein. J Neurosci 27: 5394-5404.
    • (2007) J Neurosci , vol.27 , pp. 5394-5404
    • Medeiros, R.1    Prediger, R.D.2    Passos, G.F.3    Pandolfo, P.4    Duarte, F.S.5    Franco, J.L.6
  • 82
    • 34547098824 scopus 로고    scopus 로고
    • Mosaic organization of neural stem cells in the adult brain
    • Merkle FT, Mirzadeh Z, Alvarez-Buylla A (2007). Mosaic organization of neural stem cells in the adult brain. Science 317:381-384.
    • (2007) Science , vol.317 , pp. 381-384
    • Merkle, F.T.1    Mirzadeh, Z.2    Alvarez-Buylla, A.3
  • 83
    • 0038039407 scopus 로고    scopus 로고
    • Glucose-dependent insulino-tropic polypeptide and insulin-like immunoreactivity in saliva following sham-fed and swallowed meals
    • Messenger B, Clifford MN, Morgan LM (2003). Glucose-dependent insulino-tropic polypeptide and insulin-like immunoreactivity in saliva following sham-fed and swallowed meals. J Endocrinol 177:407-412.
    • (2003) J Endocrinol , vol.177 , pp. 407-412
    • Messenger, B.1    Clifford, M.N.2    Morgan, L.M.3
  • 84
    • 0026793903 scopus 로고
    • Selective release of glutamine and glutamic acid produced by perfusion of GLP-1 (7-36) amide in the basal ganglia of the conscious rat
    • Mora F, Exposito I, Sanz B, Blazquez E (1992). Selective release of glutamine and glutamic acid produced by perfusion of GLP-1 (7-36) amide in the basal ganglia of the conscious rat. Brain Res Bull 29:359-361.
    • (1992) Brain Res Bull , vol.29 , pp. 359-361
    • Mora, F.1    Exposito, I.2    Sanz, B.3    Blazquez, E.4
  • 85
    • 0037784011 scopus 로고    scopus 로고
    • GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine
    • Mortensen K, Christensen LL, Holst JJ, Orskov C (2003). GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine. Regul Pept 114:189-196.
    • (2003) Regul Pept , vol.114 , pp. 189-196
    • Mortensen, K.1    Christensen, L.L.2    Holst, J.J.3    Orskov, C.4
  • 86
    • 0028037991 scopus 로고
    • The global burden of disease in 1990: Summary results, sensitivity analysis and future directions
    • Murray CJ, Lopez AD, Jamison DT (1994). The global burden of disease in 1990: summary results, sensitivity analysis and future directions. Bull World Health Organ 72:495-509.
    • (1994) Bull World Health Organ , vol.72 , pp. 495-509
    • Murray, C.J.1    Lopez, A.D.2    Jamison, D.T.3
  • 87
    • 20044362580 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide is expressed in adult hippocampus and induces progenitor cell proliferation
    • Nyberg J, Anderson MF, Meister B, Alborn AM, Strom AK, Brederlau A, et al. (2005). Glucose-dependent insulinotropic polypeptide is expressed in adult hippocampus and induces progenitor cell proliferation. J Neurosci 25: 1816-1825.
    • (2005) J Neurosci , vol.25 , pp. 1816-1825
    • Nyberg, J.1    Anderson, M.F.2    Meister, B.3    Alborn, A.M.4    Strom, A.K.5    Brederlau, A.6
  • 88
    • 34547444040 scopus 로고    scopus 로고
    • Immunohistochemical distribution of glucose-dependent insulinotropic polypeptide in the adult rat brain
    • Nyberg J, Jacobsson C, Anderson MF, Eriksson PS (2007). Immunohistochemical distribution of glucose-dependent insulinotropic polypeptide in the adult rat brain. J Neurosci Res 85:2099-2119.
    • (2007) J Neurosci Res , vol.85 , pp. 2099-2119
    • Nyberg, J.1    Jacobsson, C.2    Anderson, M.F.3    Eriksson, P.S.4
  • 90
    • 0033519562 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 modulates neuronal activity in the rat's hippocampus
    • Oka JI, Goto N, Kameyama T (1999). Glucagon-like peptide-1 modulates neuronal activity in the rat's hippocampus. Neuroreport 10:1643-1646.
    • (1999) Neuroreport , vol.10 , pp. 1643-1646
    • Oka, J.I.1    Goto, N.2    Kameyama, T.3
  • 91
    • 0027955170 scopus 로고
    • Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction
    • Okamoto N, Hori S, Akazawa C, Hayashi Y, Shigemoto R, Mizuno N, et al. (1994). Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction. J Biol Chem 269:1231-1236.
    • (1994) J Biol Chem , vol.269 , pp. 1231-1236
    • Okamoto, N.1    Hori, S.2    Akazawa, C.3    Hayashi, Y.4    Shigemoto, R.5    Mizuno, N.6
  • 92
    • 0041306120 scopus 로고    scopus 로고
    • Injury-induced neurogenesis in the adult mammalian brain
    • Parent JM (2003). Injury-induced neurogenesis in the adult mammalian brain. Neuroscientist 9:261-272.
    • (2003) Neuroscientist , vol.9 , pp. 261-272
    • Parent, J.M.1
  • 93
    • 19044361911 scopus 로고    scopus 로고
    • An essay on the shaking palsy. 1817
    • discussion 222
    • Parkinson J (2002). An essay on the shaking palsy. 1817. J Neuropsychiatry Clin Neurosci 14:223-236. discussion 222.
    • (2002) J Neuropsychiatry Clin Neurosci , vol.14 , pp. 223-236
    • Parkinson, J.1
  • 94
    • 22144491473 scopus 로고    scopus 로고
    • Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease
    • Perry T, Greig NH (2005). Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease. Curr Alzheimer Res 2:377-385.
    • (2005) Curr Alzheimer Res , vol.2 , pp. 377-385
    • Perry, T.1    Greig, N.H.2
  • 95
    • 0036721026 scopus 로고    scopus 로고
    • Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4
    • Perry T, Haughey NJ, Mattson MP, Egan JM, Greig NH (2002a). Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4. J Pharmacol Exp Ther 302:881-888.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 881-888
    • Perry, T.1    Haughey, N.J.2    Mattson, M.P.3    Egan, J.M.4    Greig, N.H.5
  • 96
    • 0036182251 scopus 로고    scopus 로고
    • A novel neurotrophic property of glucagon-like peptide 1: A promoter of nerve growth factor-mediated differentiation in PC12 cells
    • Perry T, Lahiri DK, Chen D, Zhou J, Shaw KT, Egan JM, et al. (2002b). A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells. J Pharmacol Exp Ther 300: 958-966.
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 958-966
    • Perry, T.1    Lahiri, D.K.2    Chen, D.3    Zhou, J.4    Shaw, K.T.5    Egan, J.M.6
  • 97
    • 0038248960 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron
    • Perry T, Lahiri DK, Sambamurti K, Chen D, Mattson MP, Egan JM, et al. (2003). Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron. J Neurosci Res 72:603-612.
    • (2003) J Neurosci Res , vol.72 , pp. 603-612
    • Perry, T.1    Lahiri, D.K.2    Sambamurti, K.3    Chen, D.4    Mattson, M.P.5    Egan, J.M.6
  • 98
    • 0017609146 scopus 로고
    • Enkephalin-like immunoreactivity in the human gastrointestinal tract
    • Polak JM, Bloom SR, Sullivan SN, Facer P, Pearse AG (1977). Enkephalin-like immunoreactivity in the human gastrointestinal tract. Lancet 1:972-974.
    • (1977) Lancet , vol.1 , pp. 972-974
    • Polak, J.M.1    Bloom, S.R.2    Sullivan, S.N.3    Facer, P.4    Pearse, A.G.5
  • 99
    • 33750619116 scopus 로고    scopus 로고
    • The risk is in the air: Intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease
    • Prediger RD, Batista LC, Medeiros R, Pandolfo P, Florio JC, Takahashi RN (2006). The risk is in the air: intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease. Exp Neurol 202:391-403.
    • (2006) Exp Neurol , vol.202 , pp. 391-403
    • Prediger, R.D.1    Batista, L.C.2    Medeiros, R.3    Pandolfo, P.4    Florio, J.C.5    Takahashi, R.N.6
  • 100
    • 33846433513 scopus 로고    scopus 로고
    • Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response
    • Prediger RD, Franco JL, Pandolfo P, Medeiros R, Duarte FS, Di Giunta G, et al. (2007). Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: evidence for a dissociation between cognitive deficits and the glutathione system response. Behav Brain Res 177:205-213.
    • (2007) Behav Brain Res , vol.177 , pp. 205-213
    • Prediger, R.D.1    Franco, J.L.2    Pandolfo, P.3    Medeiros, R.4    Duarte, F.S.5    Di Giunta, G.6
  • 101
    • 68649100468 scopus 로고    scopus 로고
    • Risk is in the air: An intranasal MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine) rat model of Parkinson's disease
    • Prediger RD, Rial D, Medeiros R, Figueiredo CP, Doty RL, Takahashi RN (2009). Risk is in the air: an intranasal MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine) rat model of Parkinson's disease. Ann N Y Acad Sci 1170:629-636.
    • (2009) Ann N y Acad Sci , vol.1170 , pp. 629-636
    • Prediger, R.D.1    Rial, D.2    Medeiros, R.3    Figueiredo, C.P.4    Doty, R.L.5    Takahashi, R.N.6
  • 102
    • 77449132053 scopus 로고    scopus 로고
    • Single intranasal administration of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine in C57BL/6 mice models early preclinical phase of Parkinson's disease
    • Prediger RD, Aguiar AS Jr, Rojas-Mayorquin AE, Figueiredo CP, Matheus FC, Ginestet L, et al. (2010). Single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice models early preclinical phase of Parkinson's disease. Neurotox Res 17:114-129.
    • (2010) Neurotox Res , vol.17 , pp. 114-129
    • Prediger, R.D.1    Aguiar Jr., A.S.2    Rojas-Mayorquin, A.E.3    Figueiredo, C.P.4    Matheus, F.C.5    Ginestet, L.6
  • 104
    • 0017377640 scopus 로고
    • Hypersecretion of gastric inhibitory polypeptide following oral glucose in diabetes mellitus
    • Ross SA, Brown JC, Dupre J (1977). Hypersecretion of gastric inhibitory polypeptide following oral glucose in diabetes mellitus. Diabetes 26:525-529.
    • (1977) Diabetes , vol.26 , pp. 525-529
    • Ross, S.A.1    Brown, J.C.2    Dupre, J.3
  • 106
    • 0035310424 scopus 로고    scopus 로고
    • Initiation of network bursts by Ca2 +-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy
    • Sanabria ER, Su H, Yaari Y (2001). Initiation of network bursts by Ca2 +-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy. J Physiol 532:205-216.
    • (2001) J Physiol , vol.532 , pp. 205-216
    • Sanabria, E.R.1    Su, H.2    Yaari, Y.3
  • 107
    • 0036340786 scopus 로고    scopus 로고
    • Damage, reorganization, and abnormal neocortical hyperexcitability in the pilocarpine model of temporal lobe epilepsy
    • Sanabria ER, Silva AV, Spreafico R, Cavalheiro EA (2002). Damage, reorganization, and abnormal neocortical hyperexcitability in the pilocarpine model of temporal lobe epilepsy. Epilepsia 43 (Suppl 5):96-106.
    • (2002) Epilepsia , vol.43 , Issue.SUPPL. 5 , pp. 96-106
    • Sanabria, E.R.1    Silva, A.V.2    Spreafico, R.3    Cavalheiro, E.A.4
  • 108
    • 2442570592 scopus 로고    scopus 로고
    • Disease modification in Parkinson's disease
    • Schapira AH (2004). Disease modification in Parkinson's disease. Lancet Neurol 3:362-368.
    • (2004) Lancet Neurol , vol.3 , pp. 362-368
    • Schapira, A.H.1
  • 110
    • 2442642871 scopus 로고    scopus 로고
    • Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus
    • Schmidt-Hieber C, Jonas P, Bischofberger J (2004). Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus. Nature 429: 184-187.
    • (2004) Nature , vol.429 , pp. 184-187
    • Schmidt-Hieber, C.1    Jonas, P.2    Bischofberger, J.3
  • 111
    • 0034511574 scopus 로고    scopus 로고
    • The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon super-family
    • Sherwood NM, Krueckl SL, McRory JE (2000). The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon super-family. Endocr Rev 21:619-670.
    • (2000) Endocr Rev , vol.21 , pp. 619-670
    • Sherwood, N.M.1    Krueckl, S.L.2    McRory, J.E.3
  • 112
    • 0018833647 scopus 로고
    • Vasoactive intestinal polypeptide (VIP) in mouse and rat brain: An immunocytochemical study
    • Sims KB, Hoffman DL, Said SI, Zimmerman EA (1980). Vasoactive intestinal polypeptide (VIP) in mouse and rat brain: an immunocytochemical study. Brain Res 186:165-183.
    • (1980) Brain Res , vol.186 , pp. 165-183
    • Sims, K.B.1    Hoffman, D.L.2    Said, S.I.3    Zimmerman, E.A.4
  • 113
    • 20144388360 scopus 로고    scopus 로고
    • Identification of hippocampus-related candidate genes for Alzheimer's disease
    • Taguchi K, Yamagata HD, Zhong W, Kamino K, Akatsu H, Hata R, et al. (2005). Identification of hippocampus-related candidate genes for Alzheimer's disease. Ann Neurol 57:585-588.
    • (2005) Ann Neurol , vol.57 , pp. 585-588
    • Taguchi, K.1    Yamagata, H.D.2    Zhong, W.3    Kamino, K.4    Akatsu, H.5    Hata, R.6
  • 114
    • 0030564998 scopus 로고    scopus 로고
    • Administration of amyloid beta-peptides in the rat medial septum causes memory deficits: Reversal by SR 57746A, a non-peptide neurotrophic compound
    • Terranova JP, Kan JP, Storme JJ, Perreaut P, Le Fur G, Soubrie P (1996). Administration of amyloid beta-peptides in the rat medial septum causes memory deficits: reversal by SR 57746A, a non-peptide neurotrophic compound. Neurosci Lett 213:79-82.
    • (1996) Neurosci Lett , vol.213 , pp. 79-82
    • Terranova, J.P.1    Kan, J.P.2    Storme, J.J.3    Perreaut, P.4    Le Fur, G.5    Soubrie, P.6
  • 115
    • 0034838323 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling
    • Trumper A, Trumper K, Trusheim H, Arnold R, Goke B, Horsch D (2001). Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling. Mol Endocrinol 15:1559-1570.
    • (2001) Mol Endocrinol , vol.15 , pp. 1559-1570
    • Trumper, A.1    Trumper, K.2    Trusheim, H.3    Arnold, R.4    Goke, B.5    Horsch, D.6
  • 116
    • 0027532178 scopus 로고
    • Glucose-dependent insulinotropic peptide: Structure of the precursor and tissue-specific expression in rat
    • Tseng CC, Jarboe LA, Landau SB, Williams EK, Wolfe MM (1993). Glucose-dependent insulinotropic peptide: structure of the precursor and tissue-specific expression in rat. Proc Natl Acad Sci\USA 90:1992-1996.
    • (1993) Proc Natl Acad Sci\USA , vol.90 , pp. 1992-1996
    • Tseng, C.C.1    Jarboe, L.A.2    Landau, S.B.3    Williams, E.K.4    Wolfe, M.M.5
  • 117
    • 0027136670 scopus 로고
    • Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain
    • Usdin TB, Mezey E, Button DC, Brownstein MJ, Bonner TI (1993). Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain. Endocrinology 133:2861-2870.
    • (1993) Endocrinology , vol.133 , pp. 2861-2870
    • Usdin, T.B.1    Mezey, E.2    Button, D.C.3    Brownstein, M.J.4    Bonner, T.I.5
  • 118
    • 0033360314 scopus 로고    scopus 로고
    • Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
    • Van Praag H, Kempermann G, Gage FH (1999). Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci 2:266-270.
    • (1999) Nat Neurosci , vol.2 , pp. 266-270
    • Van Praag, H.1    Kempermann, G.2    Gage, F.H.3
  • 119
    • 0029145003 scopus 로고
    • Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma
    • Volz A, Goke R, Lankat-Buttgereit B, Fehmann HC, Bode HP, Goke B (1995). Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma. FEBS Lett 373:23-29.
    • (1995) FEBS Lett , vol.373 , pp. 23-29
    • Volz, A.1    Goke, R.2    Lankat-Buttgereit, B.3    Fehmann, H.C.4    Bode, H.P.5    Goke, B.6
  • 120
    • 5344277556 scopus 로고    scopus 로고
    • Deciphering the molecular basis of memory failure in Alzheimer's disease
    • Walsh DM, Selkoe DJ (2004). Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 44:181-193.
    • (2004) Neuron , vol.44 , pp. 181-193
    • Walsh, D.M.1    Selkoe, D.J.2
  • 121
    • 34447544388 scopus 로고    scopus 로고
    • Pilocarpine-induced seizures cause selective time-dependent changes to adult-generated hippocampal dentate granule cells
    • Walter C, Murphy BL, Pun RY, Spieles-Engemann AL, Danzer SC (2007). Pilocarpine-induced seizures cause selective time-dependent changes to adult-generated hippocampal dentate granule cells. J Neurosci 27:7541-7552.
    • (2007) J Neurosci , vol.27 , pp. 7541-7552
    • Walter, C.1    Murphy, B.L.2    Pun, R.Y.3    Spieles-Engemann, A.L.4    Danzer, S.C.5
  • 124
    • 0028258190 scopus 로고
    • Roles of N-type and Q-type Ca2 + channels in supporting hippocampal synaptic transmission
    • Wheeler DB, Randall A, Tsien RW (1994). Roles of N-type and Q-type Ca2 + channels in supporting hippocampal synaptic transmission. Science 264:107-111.
    • (1994) Science , vol.264 , pp. 107-111
    • Wheeler, D.B.1    Randall, A.2    Tsien, R.W.3
  • 125
    • 0029082308 scopus 로고
    • Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: Ligand binding and intracellular signaling properties
    • Wheeler MB, Gelling RW, McIntosh CH, Georgiou J, Brown JC, Pederson RA (1995). Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties. Endocrinology 136:4629-4639.
    • (1995) Endocrinology , vol.136 , pp. 4629-4639
    • Wheeler, M.B.1    Gelling, R.W.2    McIntosh, C.H.3    Georgiou, J.4    Brown, J.C.5    Pederson, R.A.6
  • 126
    • 0035797593 scopus 로고    scopus 로고
    • A randomized, controlled trial of surgery for temporal-lobe epilepsy
    • Wiebe S, Blume WT, Girvin JP, Eliasziw M (2001). A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med 345:311-318.
    • (2001) N Engl J Med , vol.345 , pp. 311-318
    • Wiebe, S.1    Blume, W.T.2    Girvin, J.P.3    Eliasziw, M.4
  • 127
    • 0027397224 scopus 로고
    • Activation of metalotropic glutamate receptors increases cAMP accumulation in hippocampus by potentiating responses to endogenous adenosine
    • Winder DG, Conn PJ (1993). Activation of metalotropic glutamate receptors increases cAMP accumulation in hippocampus by potentiating responses to endogenous adenosine. J Neurosci 13:38-44.
    • (1993) J Neurosci , vol.13 , pp. 38-44
    • Winder, D.G.1    Conn, P.J.2
  • 128
    • 0032731216 scopus 로고    scopus 로고
    • Amyloid beta-(1-40) stimulates cyclic GMP production via release of kinins in primary cultured endothelial cells
    • Wirth KJ, Fink E, Rudolphi K, Heitsch H, Deutschlander N, Wiemer G (1999). Amyloid beta-(1-40) stimulates cyclic GMP production via release of kinins in primary cultured endothelial cells. Eur J Pharmacol 382:n27-n33.
    • (1999) Eur J Pharmacol , vol.382
    • Wirth, K.J.1    Fink, E.2    Rudolphi, K.3    Heitsch, H.4    Deutschlander, N.5    Wiemer, G.6
  • 129
    • 33748471099 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease: Driving force bystander or beneficial response?
    • Wyss-Coray T (2006). Inflammation in Alzheimer disease: driving force, bystander or beneficial response? Nat Med 12:1005-1015.
    • (2006) Nat Med , vol.12 , pp. 1005-1015
    • Wyss-Coray, T.1
  • 130
    • 0000380542 scopus 로고
    • Immunoassay of endogenous plasma insulin in man
    • Yalow RS, Berson SA (1960). Immunoassay of endogenous plasma insulin in man. J Clin Invest 39:1157-1175.
    • (1960) J Clin Invest , vol.39 , pp. 1157-1175
    • Yalow, R.S.1    Berson, S.A.2
  • 131
    • 0032791158 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide gene expression in the stomach: Revealed by a transgenic mouse study, in situ hybridization and immunohis-tochemical staining
    • Yeung CM, Wong CK, Chung SK, Chung SS, Chow BK (1999). Glucose-dependent insulinotropic polypeptide gene expression in the stomach: revealed by a transgenic mouse study, in situ hybridization and immunohis-tochemical staining. Mol Cell Endocrinol 154:161-170.
    • (1999) Mol Cell Endocrinol , vol.154 , pp. 161-170
    • Yeung, C.M.1    Wong, C.K.2    Chung, S.K.3    Chung, S.S.4    Chow, B.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.