A prion protein epitope selective for the pathologically misfolded conformation

Nature Medicine

Volumn 9, Issue 7, 2003, Pages 893-899

  Paramithiotis, Eustache ^a   Pinard, Marc ^a   Lawton, Trebor ^b   LaBoissiere, Sylvie ^a   Leathers, Valerie L ^b   Zou, Wen Quan ^f   Estey, Lisa A ^b   Lamontagne, Julie ^a   Lehto, Marty T ^f   Kondejewski, Leslie H ^a   Francoeur, Gregory P ^b   Papadopoulos, Maria ^a   Haghighat, Ashkan ^a   Spatz, Stephen J ^b,h   Head, Mark ^c   Will, Robert ^c   Ironside, James ^c   O'Rourke, Katherine ^d   Tonelli, Quentin ^b   Ledebur, Harry C ^a   Chakrabartty, Avi ^e   Cashman, Neil R ^a,e,f,g   more..

^a Caprion Pharmaceuticals   (Canada)

^b IDEXX LABORATORIES   (United States)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

^d WASHINGTON STATE UNIVERSITY   (United States)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF TORONTO   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

^h VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ARGININE; EPITOPE; PRION PROTEIN; TYROSINE; VIRUS ANTIBODY;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FLOW CYTOMETRY; IMMUNOASSAY; IMMUNOPRECIPITATION; NONHUMAN; PATHOGENESIS; PRION DISEASE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; ANTIBODY SPECIFICITY; CROSS REACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FLOW CYTOMETRY; HUMANS; MOLECULAR SEQUENCE DATA; PRECIPITIN TESTS; PROTEIN CONFORMATION; PROTEIN FOLDING; PRPSC PROTEINS; RABBITS; SENSITIVITY AND SPECIFICITY; SEQUENCE HOMOLOGY, AMINO ACID; TYROSINE;

EID: 0038717543     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm883     Document Type: Article

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