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Volumn 52, Issue 2, 2008, Pages 180-188

Simulation of repeated dose kinetics of methyl isobutyl ketone in humans from experimental single-dose inhalation exposure

Author keywords

12 h day 7 days week; 24 h day 7 days week; 8 h day 7 days week; Methyl isobutyl ketone; MIBK; MIBK kinetics in humans; Occupational exposure

Indexed keywords

4 METHYL 2 PENTANONE;

EID: 55949134304     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2008.08.007     Document Type: Article
Times cited : (3)

References (24)
  • 1
    • 55949088104 scopus 로고    scopus 로고
    • ACGIH (American Conference of Governmental Industrial Hygienists), 2008. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. ACGIH, Cincinnati, OH.
    • ACGIH (American Conference of Governmental Industrial Hygienists), 2008. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. ACGIH, Cincinnati, OH.
  • 2
    • 55949104246 scopus 로고    scopus 로고
    • ACGIH (American Conference of Governmental Industrial Hygienists), 2007. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. ACGIH, Cincinnati, OH.
    • ACGIH (American Conference of Governmental Industrial Hygienists), 2007. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. ACGIH, Cincinnati, OH.
  • 3
    • 55949098305 scopus 로고    scopus 로고
    • AIHA (American Industrial Hygiene Association), 1995. Odor thresholds for chemicals with established occupational health standards. AIHA, Fairfax, VA.
    • AIHA (American Industrial Hygiene Association), 1995. Odor thresholds for chemicals with established occupational health standards. AIHA, Fairfax, VA.
  • 4
    • 55949137322 scopus 로고    scopus 로고
    • Armeli, G., Linari, F., Martorano, G., 1968. Rilievi clinici ed ematochimici in operai esposti all'arione di un chetone superione (MIBK) ripetuti a distanza di 5 anni. Lav. Urnano. 20, 418-423 (cited in: Health and Safety Commission, Health Directorate 98/24/EC, Chemical Policy Division, London, 2000).
    • Armeli, G., Linari, F., Martorano, G., 1968. Rilievi clinici ed ematochimici in operai esposti all'arione di un chetone superione (MIBK) ripetuti a distanza di 5 anni. Lav. Urnano. 20, 418-423 (cited in: Health and Safety Commission, Health Directorate 98/24/EC, Chemical Policy Division, London, 2000).
  • 5
    • 0026674051 scopus 로고
    • Neurobehavioral effects from acute exposures to methyl isobutyl ketone and methyl ethyl ketone
    • Dick R.B., Krieg Jr. E.F., Setzer J., and Taylor B. Neurobehavioral effects from acute exposures to methyl isobutyl ketone and methyl ethyl ketone. Fundam. Appl. Toxicol. 19 (1992) 453-473
    • (1992) Fundam. Appl. Toxicol. , vol.19 , pp. 453-473
    • Dick, R.B.1    Krieg Jr., E.F.2    Setzer, J.3    Taylor, B.4
  • 6
    • 0017072068 scopus 로고
    • Characterization of the metabolites of methyl n-butyl ketone, methyl iso-butyl ketone and methyl ethyl ketone in guinea pig serum and their clearance
    • DiVincenzo G.D., Kaplan C.J., and Dedinas J. Characterization of the metabolites of methyl n-butyl ketone, methyl iso-butyl ketone and methyl ethyl ketone in guinea pig serum and their clearance. Toxicol. Appl. Pharmacol. 36 (1976) 511-522
    • (1976) Toxicol. Appl. Pharmacol. , vol.36 , pp. 511-522
    • DiVincenzo, G.D.1    Kaplan, C.J.2    Dedinas, J.3
  • 7
    • 55949091016 scopus 로고    scopus 로고
    • EPA (U.S. Environmental Protection Agency), Alpha 2μ-Globulin: Association with Chemically Induced Renal Toxicity and Neoplasia in the Male Rat. U.S. EPA. Document Number EPA/625/3-91/019F, Washington, D.C., 1991.
    • EPA (U.S. Environmental Protection Agency), Alpha 2μ-Globulin: Association with Chemically Induced Renal Toxicity and Neoplasia in the Male Rat. U.S. EPA. Document Number EPA/625/3-91/019F, Washington, D.C., 1991.
  • 8
    • 55949095044 scopus 로고
    • Chemical Hazard Evaluation and Communication Program, Biomedical and Environmental Information Analysis Section, Health Sciences Research Division, Oak Ridge, TN
    • Faust R.A. Toxicity Summary for Methyl Isobutyl Ketone (1995), Chemical Hazard Evaluation and Communication Program, Biomedical and Environmental Information Analysis Section, Health Sciences Research Division, Oak Ridge, TN
    • (1995) Toxicity Summary for Methyl Isobutyl Ketone
    • Faust, R.A.1
  • 9
    • 0018639251 scopus 로고
    • Effects of acetone, methyl ethyl ketone and methyl isobutyl ketone on a match-to-match sample task in the baboon
    • Geller I., Gause E., Kaplan H., and Hartmann R.J. Effects of acetone, methyl ethyl ketone and methyl isobutyl ketone on a match-to-match sample task in the baboon. Pharmacol. Biochem. Behav. 11 (1979) 401-406
    • (1979) Pharmacol. Biochem. Behav. , vol.11 , pp. 401-406
    • Geller, I.1    Gause, E.2    Kaplan, H.3    Hartmann, R.J.4
  • 10
    • 55949128373 scopus 로고    scopus 로고
    • Methyl isobutyl ketone (MIBK) induced α-2-μ globulin (α2μ) nephropathy in male and female F344 rats. Abstract 465
    • Hard G.C., Berdasco N., Gingell R., Green S., Gulledge W., and Borghoff S. Methyl isobutyl ketone (MIBK) induced α-2-μ globulin (α2μ) nephropathy in male and female F344 rats. Abstract 465. Toxicologist (2008) 102
    • (2008) Toxicologist , pp. 102
    • Hard, G.C.1    Berdasco, N.2    Gingell, R.3    Green, S.4    Gulledge, W.5    Borghoff, S.6
  • 11
    • 0025128489 scopus 로고
    • Exposure to methyl isobutyl ketone: toxicokinetics and occurrence of irritative and CNS symptoms in man
    • Hjelm E.W., Hagberg M., Iregren A., and Lof A. Exposure to methyl isobutyl ketone: toxicokinetics and occurrence of irritative and CNS symptoms in man. Int. Arch. Occup. Environ. Health 62 (1990) 19-26
    • (1990) Int. Arch. Occup. Environ. Health , vol.62 , pp. 19-26
    • Hjelm, E.W.1    Hagberg, M.2    Iregren, A.3    Lof, A.4
  • 12
    • 55949084131 scopus 로고    scopus 로고
    • HSC (Health and Safety Commission), 2000. European Commission Directive Under the Chemical Agents Directive 98/24/EC to establish a First Consolidated List of Indicative Occupational Exposure Limit Values at European Community Level. Health Directorate, Chemical Policy Division, London, 2000.
    • HSC (Health and Safety Commission), 2000. European Commission Directive Under the Chemical Agents Directive 98/24/EC to establish a First Consolidated List of Indicative Occupational Exposure Limit Values at European Community Level. Health Directorate, Chemical Policy Division, London, 2000.
  • 13
    • 0037607104 scopus 로고    scopus 로고
    • Methyl isobytyl ketone and methyl ethyl ketone in urine as biological markers of occupational exposure to these solvents at low levels
    • Kawai T., Zhang Z.-W., Takeuchi A., Miyama Y., Sakamoto K., Higashikawa K., and Ikeda M. Methyl isobytyl ketone and methyl ethyl ketone in urine as biological markers of occupational exposure to these solvents at low levels. Int. Arch. Occup. Environ. Health 76 (2003) 17-23
    • (2003) Int. Arch. Occup. Environ. Health , vol.76 , pp. 17-23
    • Kawai, T.1    Zhang, Z.-W.2    Takeuchi, A.3    Miyama, Y.4    Sakamoto, K.5    Higashikawa, K.6    Ikeda, M.7
  • 14
    • 55949124916 scopus 로고
    • Rilievi clinici ed ematochimici in operai esposti all'azione di un chetone superiore: metil-isobutil-c he tone
    • (cited in: Health and Safety Commission, Health Directorate 98/24/EC, Chemical Policy Division, London, 2000).
    • Linari F., Perelli G., and Varese D. Rilievi clinici ed ematochimici in operai esposti all'azione di un chetone superiore: metil-isobutil-c he tone. Arch. Sci. Med. (1964) 226-237 (cited in: Health and Safety Commission, Health Directorate 98/24/EC, Chemical Policy Division, London, 2000).
    • (1964) Arch. Sci. Med. , pp. 226-237
    • Linari, F.1    Perelli, G.2    Varese, D.3
  • 15
    • 55949103072 scopus 로고    scopus 로고
    • MacEwens, J.D., Vernot, E.H., Haun, C.C., Effect of 90-day continuous exposure to methyl isobutyl ketone on dogs, monkeys and rats. Joint NASA/USAF study. National Technical Information Service, Springfied, VA. NTIS AD 730 291, 1971.
    • MacEwens, J.D., Vernot, E.H., Haun, C.C., Effect of 90-day continuous exposure to methyl isobutyl ketone on dogs, monkeys and rats. Joint NASA/USAF study. National Technical Information Service, Springfied, VA. NTIS AD 730 291, 1971.
  • 16
    • 55949085896 scopus 로고    scopus 로고
    • Maurissen, J.P., 2007. Review of Geller et al. for the MIBK ACGIH TLV Derivation. Communication to the ACC Ketones Panel, 6/18/07.
    • Maurissen, J.P., 2007. Review of Geller et al. for the MIBK ACGIH TLV Derivation. Communication to the ACC Ketones Panel, 6/18/07.
  • 17
    • 55949094767 scopus 로고    scopus 로고
    • NTP (National Toxicology Program), 2007. NTP Toxicology and Carcinogenesis Studies of Methyl Isobutyl Ketone (CAS No. 108-10-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). NIEHS, Research Triangle Park, North Carolina, NTP Tech. Rep. Ser. 538, 1-236.
    • NTP (National Toxicology Program), 2007. NTP Toxicology and Carcinogenesis Studies of Methyl Isobutyl Ketone (CAS No. 108-10-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). NIEHS, Research Triangle Park, North Carolina, NTP Tech. Rep. Ser. 538, 1-236.
  • 18
    • 0028881788 scopus 로고
    • Evaluation of exposure to solvents from their urinary excretion in workers coexposed to toluene, xylene, and methyl isobutyl ketone
    • Ogata M., Taguchi T., and Horike T. Evaluation of exposure to solvents from their urinary excretion in workers coexposed to toluene, xylene, and methyl isobutyl ketone. Appl. Occup. Environ. Hyg. 10 (1995) 913-920
    • (1995) Appl. Occup. Environ. Hyg. , vol.10 , pp. 913-920
    • Ogata, M.1    Taguchi, T.2    Horike, T.3
  • 19
    • 55949133311 scopus 로고    scopus 로고
    • OSHA (Occupational Safety & Health Administration), 2008. 2-Butanone (MEK) Hexone (MIBK). Occupational Safety & Health Administration, Washington, D.C.
    • OSHA (Occupational Safety & Health Administration), 2008. 2-Butanone (MEK) Hexone (MIBK). Occupational Safety & Health Administration, Washington, D.C.
  • 22
    • 0004790930 scopus 로고
    • Further studies on sensory response to certain industrial solvent vapors
    • Silverman L., Schulte H.F., and First M.W. Further studies on sensory response to certain industrial solvent vapors. J. Ind. Hyg. Toxicol. 28 (1946) 262-266
    • (1946) J. Ind. Hyg. Toxicol. , vol.28 , pp. 262-266
    • Silverman, L.1    Schulte, H.F.2    First, M.W.3
  • 23
    • 38749094436 scopus 로고    scopus 로고
    • Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure
    • Stout M.D., Herbert R.A., Kissling G.E., Suarez F., Roycroft J.H., Chhabra R.S., and Bucher J.R. Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure. Toxicology 244 (2008) 209-219
    • (2008) Toxicology , vol.244 , pp. 209-219
    • Stout, M.D.1    Herbert, R.A.2    Kissling, G.E.3    Suarez, F.4    Roycroft, J.H.5    Chhabra, R.S.6    Bucher, J.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.