메뉴 건너뛰기




Volumn 342, Issue 1-2, 2010, Pages 241-250

Differentiation linked regulation of telomerase activity by Makorin-1

Author keywords

hTERT; Makorin 1; Proteasome; Telomerase; Ubiquitin; Ubiquitin ligase

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; MAKORIN 1; MESSENGER RNA; TELOMERASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 77955852573     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-010-0490-x     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • DOI 10.1016/S0092-8674(01)00492-5
    • EH Blackburn 2001 Switching and signaling at the telomere Cell 106 661 673 10.1016/S0092-8674(01)00492-5 1:CAS:528:DC%2BD3MXnslGkt7c%3D 11572773 (Pubitemid 32900658)
    • (2001) Cell , vol.106 , Issue.6 , pp. 661-673
    • Blackburn, E.H.1
  • 2
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • DOI 10.1101/gad.1346005
    • T de Lange 2005 Shelterin: the protein complex that shapes and safeguards human telomeres Genes Dev 19 2100 2110 10.1101/gad.1346005 16166375 (Pubitemid 41330312)
    • (2005) Genes and Development , vol.19 , Issue.18 , pp. 2100-2110
    • De Lange, T.1
  • 3
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • 10.1146/annurev.genet.41.110306.130350 1:CAS:528:DC%2BD1cXhsFemtbrI 18680434
    • W Palm T de Lange 2008 How shelterin protects mammalian telomeres Annu Rev Genet 42 301 334 10.1146/annurev.genet.41.110306.130350 1:CAS:528: DC%2BD1cXhsFemtbrI 18680434
    • (2008) Annu Rev Genet , vol.42 , pp. 301-334
    • Palm, W.1    De Lange, T.2
  • 4
    • 0030931491 scopus 로고    scopus 로고
    • Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
    • DOI 10.1016/S0092-8674(01)80006-4
    • MA Blasco HW Lee MP Hande E Samper PM Lansdorp RA DePinho CW Greider 1997 Telomere shortening and tumor formation by mouse cells lacking telomerase RNA Cell 91 25 34 10.1016/S0092-8674(01)80006-4 1:CAS:528:DyaK2sXmslGgt7w%3D 9335332 (Pubitemid 27431310)
    • (1997) Cell , vol.91 , Issue.1 , pp. 25-34
    • Blasco, M.A.1    Lee, H.-W.2    Hande, M.P.3    Samper, E.4    Lansdorp, P.M.5    DePinho, R.A.6    Greider, C.W.7
  • 5
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • 1:CAS:528:DyaK38XktVait7g%3D 1582420
    • CM Counter AA Avilion CE LeFeuvre NG Stewart CW Greider CB Harley S Bacchetti 1992 Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity EMBO J 11 1921 1929 1:CAS:528:DyaK38XktVait7g%3D 1582420
    • (1992) EMBO J , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    Lefeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 6
    • 0031302895 scopus 로고    scopus 로고
    • Telomerase and the chromosome end replication problem
    • 1:CAS:528:DyaK1cXmvFalurc%3D 9524749 (discussion 28-34)
    • TR Cech J Lingner 1997 Telomerase and the chromosome end replication problem Ciba Found Symp 211 20 28 1:CAS:528:DyaK1cXmvFalurc%3D 9524749 (discussion 28-34)
    • (1997) Ciba Found Symp , vol.211 , pp. 20-28
    • Cech, T.R.1    Lingner, J.2
  • 9
    • 0029066169 scopus 로고
    • Telomerase activity in normal and malignant hematopoietic cells
    • 10.1073/pnas.92.20.9082 1:CAS:528:DyaK2MXosVWlsLg%3D 7568077
    • D Broccoli JW Young T de Lange 1995 Telomerase activity in normal and malignant hematopoietic cells Proc Natl Acad Sci USA 92 9082 9086 10.1073/pnas.92.20.9082 1:CAS:528:DyaK2MXosVWlsLg%3D 7568077
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9082-9086
    • Broccoli, D.1    Young, J.W.2    De Lange, T.3
  • 10
    • 0028938262 scopus 로고
    • Telomerase activity in normal leukocytes and in hematologic malignancies
    • 1:CAS:528:DyaK2MXlt1Omuro%3D 7727765
    • CM Counter J Gupta CB Harley B Leber S Bacchetti 1995 Telomerase activity in normal leukocytes and in hematologic malignancies Blood 85 2315 2320 1:CAS:528:DyaK2MXlt1Omuro%3D 7727765
    • (1995) Blood , vol.85 , pp. 2315-2320
    • Counter, C.M.1    Gupta, J.2    Harley, C.B.3    Leber, B.4    Bacchetti, S.5
  • 11
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • DOI 10.1016/S0959-8049(97)00062-2, PII S0959804997000622
    • JW Shay S Bacchetti 1997 A survey of telomerase activity in human cancer Eur J Cancer 33 787 791 10.1016/S0959-8049(97)00062-2 1:STN:280: DyaK2svis12qug%3D%3D 9282118 (Pubitemid 27239490)
    • (1997) European Journal of Cancer Part A , vol.33 , Issue.5 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 12
    • 0029128798 scopus 로고
    • Telomerase and DNA end replication: No longer a lagging strand problem?
    • 10.1126/science.7545310 1:CAS:528:DyaK2MXotVOgsb8%3D 7545310
    • J Lingner JP Cooper TR Cech 1995 Telomerase and DNA end replication: no longer a lagging strand problem? Science 269 1533 1534 10.1126/science.7545310 1:CAS:528:DyaK2MXotVOgsb8%3D 7545310
    • (1995) Science , vol.269 , pp. 1533-1534
    • Lingner, J.1    Cooper, J.P.2    Cech, T.R.3
  • 13
    • 0032765047 scopus 로고    scopus 로고
    • Studies of the molecular mechanisms in the regulation of telomerase activity
    • 1:CAS:528:DyaK1MXotVKit7k%3D 10593857
    • JP Liu 1999 Studies of the molecular mechanisms in the regulation of telomerase activity FASEB J 13 2091 2104 1:CAS:528:DyaK1MXotVKit7k%3D 10593857
    • (1999) FASEB J , vol.13 , pp. 2091-2104
    • Liu, J.P.1
  • 14
    • 5444238109 scopus 로고    scopus 로고
    • Genetic and epigenetic modulation of telomerase activity in development and disease
    • DOI 10.1016/j.gene.2004.06.011, PII S037811190400335X
    • L Liu S Lai LG Andrews TO Tollefsbol 2004 Genetic and epigenetic modulation of telomerase activity in development and disease Gene 340 1 10 10.1016/j.gene.2004.06.011 1:CAS:528:DC%2BD2cXns1Clt70%3D 15556289 (Pubitemid 39360227)
    • (2004) Gene , vol.340 , Issue.1 , pp. 1-10
    • Liu, L.1    Lai, S.2    Andrews, L.G.3    Tollefsbol, T.O.4
  • 16
    • 29244483930 scopus 로고    scopus 로고
    • CTCF binds the proximal exonic region of hTERT and inhibits its transcription
    • DOI 10.1093/nar/gki989
    • S Renaud D Loukinov FT Bosman V Lobanenkov J Benhattar 2005 CTCF binds the proximal exonic region of hTERT and inhibits its transcription Nucleic Acids Res 33 6850 6860 10.1093/nar/gki989 1:CAS:528:DC%2BD2MXhtlagtbfI 16326864 (Pubitemid 41830489)
    • (2005) Nucleic Acids Research , vol.33 , Issue.21 , pp. 6850-6860
    • Renaud, S.1    Loukinov, D.2    Bosman, F.T.3    Lobanenkov, V.4    Benhattar, J.5
  • 17
    • 2642610318 scopus 로고    scopus 로고
    • Myc activates telomerase
    • 10.1101/gad.12.12.1769 1:CAS:528:DyaK1cXktl2isbk%3D 9637678
    • J Wang LY Xie S Allan D Beach GJ Hannon 1998 Myc activates telomerase Genes Dev 12 1769 1774 10.1101/gad.12.12.1769 1:CAS:528:DyaK1cXktl2isbk%3D 9637678
    • (1998) Genes Dev , vol.12 , pp. 1769-1774
    • Wang, J.1    Xie, L.Y.2    Allan, S.3    Beach, D.4    Hannon, G.J.5
  • 18
    • 34547807674 scopus 로고    scopus 로고
    • Site-specific methylation of CpG nucleotides in the hTERT promoter region can control the expression of hTERT during malignant progression of colorectal carcinoma
    • DOI 10.1016/j.bbrc.2007.07.051, PII S0006291X07015318
    • JH Choi SH Park J Park BG Park SJ Cha KH Kong KH Lee AJ Park 2007 Site-specific methylation of CpG nucleotides in the hTERT promoter region can control the expression of hTERT during malignant progression of colorectal carcinoma Biochem Biophys Res Commun 361 615 620 10.1016/j.bbrc.2007.07.051 1:CAS:528:DC%2BD2sXovFOktL0%3D 17673177 (Pubitemid 47238031)
    • (2007) Biochemical and Biophysical Research Communications , vol.361 , Issue.3 , pp. 615-620
    • Choi, J.-H.1    Park, S.H.2    Park, J.3    Park, B.G.4    Cha, S.-J.5    Kong, K.-H.6    Lee, K.-H.7    Park, A.J.8
  • 19
    • 0141788590 scopus 로고    scopus 로고
    • Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres
    • DOI 10.1016/S0014-4827(03)00281-7
    • I Guilleret J Benhattar 2003 Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres Exp Cell Res 289 326 334 10.1016/S0014-4827(03) 00281-7 1:CAS:528:DC%2BD3sXnt1Ggtbg%3D 14499633 (Pubitemid 37117418)
    • (2003) Experimental Cell Research , vol.289 , Issue.2 , pp. 326-334
    • Guilleret, I.1    Benhattar, J.2
  • 20
    • 3342913667 scopus 로고    scopus 로고
    • Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation
    • DOI 10.1002/gcc.20058
    • L Liu SN Saldanha MS Pate LG Andrews TO Tollefsbol 2004 Epigenetic regulation of human telomerase reverse transcriptase promoter activity during cellular differentiation Genes Chromosomes Cancer 41 26 37 10.1002/gcc.20058 1:CAS:528:DC%2BD2cXntVelurY%3D 15236314 (Pubitemid 38988735)
    • (2004) Genes Chromosomes and Cancer , vol.41 , Issue.1 , pp. 26-37
    • Liu, L.1    Saldanha, S.N.2    Pate, M.S.3    Andrews, L.G.4    Tollefsbol, T.O.5
  • 22
    • 34047137148 scopus 로고    scopus 로고
    • Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene
    • DOI 10.1093/nar/gkl1125
    • S Renaud D Loukinov Z Abdullaev I Guilleret FT Bosman V Lobanenkov J Benhattar 2007 Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene Nucleic Acids Res 35 1245 1256 10.1093/nar/gkl1125 1:CAS:528:DC%2BD2sXjslOgsb8%3D 17267411 (Pubitemid 46522976)
    • (2007) Nucleic Acids Research , vol.35 , Issue.4 , pp. 1245-1256
    • Renaud, S.1    Loukinov, D.2    Abdullaev, Z.3    Guilleret, I.4    Bosman, F.T.5    Lobanenkov, V.6    Benhattar, J.7
  • 23
    • 40249100742 scopus 로고    scopus 로고
    • Epigenetic regulation of telomerase in retinoid-induced differentiation of human leukemia cells
    • 1:CAS:528:DC%2BD1cXjs1Cmurs%3D 18292940
    • WK Love JB Berletch LG Andrews TO Tollefsbol 2008 Epigenetic regulation of telomerase in retinoid-induced differentiation of human leukemia cells Int J Oncol 32 625 631 1:CAS:528:DC%2BD1cXjs1Cmurs%3D 18292940
    • (2008) Int J Oncol , vol.32 , pp. 625-631
    • Love, W.K.1    Berletch, J.B.2    Andrews, L.G.3    Tollefsbol, T.O.4
  • 24
    • 0032530136 scopus 로고    scopus 로고
    • Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts
    • 1:CAS:528:DyaK1cXmtlCksL0%3D 9751630
    • GA Ulaner JF Hu TH Vu LC Giudice AR Hoffman 1998 Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts Cancer Res 58 4168 4172 1:CAS:528:DyaK1cXmtlCksL0%3D 9751630
    • (1998) Cancer Res , vol.58 , pp. 4168-4172
    • Ulaner, G.A.1    Hu, J.F.2    Vu, T.H.3    Giudice, L.C.4    Hoffman, A.R.5
  • 25
    • 40749135820 scopus 로고    scopus 로고
    • Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly
    • DOI 10.1016/j.cell.2008.01.019, PII S0092867408001190
    • AS Venteicher Z Meng PJ Mason TD Veenstra SE Artandi 2008 Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly Cell 132 945 957 10.1016/j.cell.2008.01.019 1:CAS:528: DC%2BD1cXkt1Wqs7Y%3D 18358808 (Pubitemid 351381739)
    • (2008) Cell , vol.132 , Issue.6 , pp. 945-957
    • Venteicher, A.S.1    Meng, Z.2    Mason, P.J.3    Veenstra, T.D.4    Artandi, S.E.5
  • 26
    • 0033532056 scopus 로고    scopus 로고
    • Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit
    • DOI 10.1074/jbc.274.19.13085
    • SS Kang T Kwon DY Kwon SI Do 1999 Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit J Biol Chem 274 13085 13090 10.1074/jbc.274.19.13085 1:CAS:528:DyaK1MXjtFOlsro%3D 10224060 (Pubitemid 29220430)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.19 , pp. 13085-13090
    • Kang, S.S.1    Kwon, T.2    Kwon, D.Y.3    Do, S.I.4
  • 27
    • 0032509350 scopus 로고    scopus 로고
    • Telomerase is controlled by protein kinase Cα in human breast cancer cells
    • DOI 10.1074/jbc.273.50.33436
    • H Li L Zhao Z Yang JW Funder JP Liu 1998 Telomerase is controlled by protein kinase Calpha in human breast cancer cells J Biol Chem 273 33436 33442 10.1074/jbc.273.50.33436 1:CAS:528:DyaK1MXmtVM%3D 9837921 (Pubitemid 29005724)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.50 , pp. 33436-33442
    • Li, H.1    Zhao, L.2    Yang, Z.3    Funder, J.W.4    Liu, J.-P.5
  • 28
    • 0030755955 scopus 로고    scopus 로고
    • Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells
    • DOI 10.1074/jbc.272.27.16729
    • H Li LL Zhao JW Funder JP Liu 1997 Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells J Biol Chem 272 16729 16732 10.1074/jbc.272.27.16729 1:CAS:528:DyaK2sXksVentbc%3D 9201974 (Pubitemid 27289765)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.27 , pp. 16729-16732
    • Li, H.1    Zhao, L.-L.2    Funder, J.W.3    Liu, J.-P.4
  • 29
    • 0035871710 scopus 로고    scopus 로고
    • Cutting edge: Telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation
    • 1:CAS:528:DC%2BD3MXivVKnurs%3D 11290757
    • K Liu RJ Hodes N Weng 2001 Cutting edge: telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation J Immunol 166 4826 4830 1:CAS:528:DC%2BD3MXivVKnurs%3D 11290757
    • (2001) J Immunol , vol.166 , pp. 4826-4830
    • Liu, K.1    Hodes, R.J.2    Weng, N.3
  • 30
    • 0035798379 scopus 로고    scopus 로고
    • The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor
    • DOI 10.1016/S0092-8674(01)00538-4
    • XZ Zhou KP Lu 2001 The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor Cell 107 347 359 10.1016/S0092-8674(01)00538-4 1:CAS:528:DC%2BD3MXosVKhsbw%3D 11701125 (Pubitemid 33049978)
    • (2001) Cell , vol.107 , Issue.3 , pp. 347-359
    • Zhou, X.Z.1    Lu, K.P.2
  • 31
    • 4544379480 scopus 로고    scopus 로고
    • DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase
    • DOI 10.1074/jbc.M401843200
    • GE Lee EY Yu CH Cho J Lee MT Muller IK Chung 2004 DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase J Biol Chem 279 34750 34755 10.1074/jbc.M401843200 1:CAS:528:DC%2BD2cXmvFems7g%3D 15190070 (Pubitemid 39318106)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.33 , pp. 34750-34755
    • Gun, E.L.1    Eun, Y.Y.2    Chae, H.C.3    Lee, J.4    Muller, M.T.5    In, K.C.6
  • 32
    • 0035844136 scopus 로고    scopus 로고
    • Stable association of hsp90 and p23, but Not hsp70, with active human telomerase
    • 10.1074/jbc.C100055200 1:CAS:528:DC%2BD3MXjvFalurs%3D 11274138
    • HL Forsythe JL Jarvis JW Turner LW Elmore SE Holt 2001 Stable association of hsp90 and p23, but Not hsp70, with active human telomerase J Biol Chem 276 15571 15574 10.1074/jbc.C100055200 1:CAS:528:DC%2BD3MXjvFalurs%3D 11274138
    • (2001) J Biol Chem , vol.276 , pp. 15571-15574
    • Forsythe, H.L.1    Jarvis, J.L.2    Turner, J.W.3    Elmore, L.W.4    Holt, S.E.5
  • 34
    • 0031043509 scopus 로고    scopus 로고
    • Telomerase activity is induced in human peripheral B lymphocytes by the stimulation to antigen receptor
    • 1:CAS:528:DyaK2sXhtFagt78%3D 9028953
    • H Igarashi N Sakaguchi 1997 Telomerase activity is induced in human peripheral B lymphocytes by the stimulation to antigen receptor Blood 89 1299 1307 1:CAS:528:DyaK2sXhtFagt78%3D 9028953
    • (1997) Blood , vol.89 , pp. 1299-1307
    • Igarashi, H.1    Sakaguchi, N.2
  • 35
    • 17044367499 scopus 로고    scopus 로고
    • Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT
    • 10.1101/gad.1289405 1:CAS:528:DC%2BD2MXjt1OjtLo%3D 15805468
    • JH Kim SM Park MR Kang SY Oh TH Lee MT Muller IK Chung 2005 Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT Genes Dev 19 776 781 10.1101/gad.1289405 1:CAS:528:DC%2BD2MXjt1OjtLo%3D 15805468
    • (2005) Genes Dev , vol.19 , pp. 776-781
    • Kim, J.H.1    Park, S.M.2    Kang, M.R.3    Oh, S.Y.4    Lee, T.H.5    Muller, M.T.6    Chung, I.K.7
  • 36
    • 0034657440 scopus 로고    scopus 로고
    • 3H zinc-finger motifs with abundant expression in developing brain and nervous system
    • DOI 10.1006/geno.2000.6199
    • TA Gray L Hernandez AH Carey MA Schaldach MJ Smithwick K Rus JA Marshall Graves CL Stewart RD Nicholls 2000 The ancient source of a distinct gene family encoding proteins featuring RING and C(3)H zinc-finger motifs with abundant expression in developing brain and nervous system Genomics 66 76 86 10.1006/geno.2000.6199 1:CAS:528:DC%2BD3cXjslKiu7w%3D 10843807 (Pubitemid 30347174)
    • (2000) Genomics , vol.66 , Issue.1 , pp. 76-86
    • Gray, T.A.1    Hernandez, L.2    Carey, A.H.3    Schaldach, M.A.4    Smithwick, M.J.5    Rus, K.6    Marshall Graves, J.A.7    Stewart, C.L.8    Nicholls, R.D.9
  • 37
    • 67649763465 scopus 로고    scopus 로고
    • Ubiquitin ligase RLIM modulates telomere length homeostasis through a proteolysis of TRF1
    • 10.1074/jbc.M806702200 1:CAS:528:DC%2BD1MXjsVSitro%3D 19164295
    • YR Her IK Chung 2009 Ubiquitin ligase RLIM modulates telomere length homeostasis through a proteolysis of TRF1 J Biol Chem 284 8557 8566 10.1074/jbc.M806702200 1:CAS:528:DC%2BD1MXjsVSitro%3D 19164295
    • (2009) J Biol Chem , vol.284 , pp. 8557-8566
    • Her, Y.R.1    Chung, I.K.2
  • 38
    • 4444232234 scopus 로고    scopus 로고
    • Telomerase inhibition by retinoids precedes cytodifferentiation of leukemia cells and may contribute to terminal differentiation
    • 1:CAS:528:DC%2BD2cXmtleks7k%3D 15299083
    • L Liu JB Berletch JG Green MS Pate LG Andrews TO Tollefsbol 2004 Telomerase inhibition by retinoids precedes cytodifferentiation of leukemia cells and may contribute to terminal differentiation Mol Cancer Ther 3 1003 1009 1:CAS:528:DC%2BD2cXmtleks7k%3D 15299083
    • (2004) Mol Cancer Ther , vol.3 , pp. 1003-1009
    • Liu, L.1    Berletch, J.B.2    Green, J.G.3    Pate, M.S.4    Andrews, L.G.5    Tollefsbol, T.O.6
  • 39
    • 0031845746 scopus 로고    scopus 로고
    • Down-regulation of telomerase activity is an early event of cellular differentiation without apparent telomeric DNA change
    • DOI 10.1016/S0145-2126(98)00065-4, PII S0145212698000654
    • O Yamada M Takanashi M Ujihara H Mizoguchi 1998 Down-regulation of telomerase activity is an early event of cellular differentiation without apparent telomeric DNA change Leuk Res 22 711 717 10.1016/S0145-2126(98)00065-4 1:CAS:528:DyaK1cXkvVCisbg%3D 9680098 (Pubitemid 28327477)
    • (1998) Leukemia Research , vol.22 , Issue.8 , pp. 711-717
    • Yamada, O.1    Takanashi, M.2    Ujihara, M.3    Mizoguchi, H.4
  • 40
    • 0344255770 scopus 로고    scopus 로고
    • Mechanisms involved in the induced differentiation of leukemia cells
    • DOI 10.1016/j.pharmthera.2003.09.002
    • AS Tsiftsoglou IS Pappas IS Vizirianakis 2003 Mechanisms involved in the induced differentiation of leukemia cells Pharmacol Ther 100 257 290 10.1016/j.pharmthera.2003.09.002 1:CAS:528:DC%2BD3sXptlylsrw%3D 14652113 (Pubitemid 37494909)
    • (2003) Pharmacology and Therapeutics , vol.100 , Issue.3 , pp. 257-290
    • Tsiftsoglou, A.S.1    Pappas, I.S.2    Vizirianakis, I.S.3
  • 41
    • 46949095096 scopus 로고    scopus 로고
    • Multistep regulation of telomerase during differentiation of HL60 cells
    • DOI 10.1189/jlb.1207848
    • O Yamada K Ozaki M Nakatake M Akiyama K Kawauchi R Matsuoka 2008 Multistep regulation of telomerase during differentiation of HL60 cells J Leukoc Biol 83 1240 1248 10.1189/jlb.1207848 1:CAS:528:DC%2BD1cXlsVWnsL4%3D 18276798 (Pubitemid 351960356)
    • (2008) Journal of Leukocyte Biology , vol.83 , Issue.5 , pp. 1240-1248
    • Yamada, O.1    Ozaki, K.2    Nakatake, M.3    Akiyama, M.4    Kawauchi, K.5    Matsuoka, R.6
  • 43
    • 54249087929 scopus 로고    scopus 로고
    • Suppression of hPOT1 in diploid human cells results in an hTERT-dependent alteration of telomere length dynamics
    • 10.1158/1541-7786.MCR-08-0070 1:CAS:528:DC%2BD1cXht1Cmsb7E 18922974
    • R Possemato JC Timmons EL Bauerlein N Wada A Baldwin K Masutomi WC Hahn 2008 Suppression of hPOT1 in diploid human cells results in an hTERT-dependent alteration of telomere length dynamics Mol Cancer Res 6 1582 1593 10.1158/1541-7786.MCR-08-0070 1:CAS:528:DC%2BD1cXht1Cmsb7E 18922974
    • (2008) Mol Cancer Res , vol.6 , pp. 1582-1593
    • Possemato, R.1    Timmons, J.C.2    Bauerlein, E.L.3    Wada, N.4    Baldwin, A.5    Masutomi, K.6    Hahn, W.C.7
  • 44
    • 67651154117 scopus 로고    scopus 로고
    • Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis
    • 10.1038/emboj.2009.164 1:CAS:528:DC%2BD1MXnsVans7o%3D 19536131
    • EW Lee MS Lee S Camus J Ghim MR Yang W Oh NC Ha DP Lane J Song 2009 Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis EMBO J 28 2100 2113 10.1038/emboj.2009.164 1:CAS:528:DC%2BD1MXnsVans7o%3D 19536131
    • (2009) EMBO J , vol.28 , pp. 2100-2113
    • Lee, E.W.1    Lee, M.S.2    Camus, S.3    Ghim, J.4    Yang, M.R.5    Oh, W.6    Ha, N.C.7    Lane, D.P.8    Song, J.9
  • 45
    • 0033568014 scopus 로고    scopus 로고
    • Normal human telomeres are not late replicating
    • DOI 10.1006/excr.1999.4602
    • WE Wright VM Tesmer ML Liao JW Shay 1999 Normal human telomeres are not late replicating Exp Cell Res 251 492 499 10.1006/excr.1999.4602 1:CAS:528:DyaK1MXlsFyhs7k%3D 10471333 (Pubitemid 29431885)
    • (1999) Experimental Cell Research , vol.251 , Issue.2 , pp. 492-499
    • Wright, W.E.1    Tesmer, V.M.2    Liao, M.L.3    Shay, J.W.4
  • 46
    • 68049088928 scopus 로고    scopus 로고
    • Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells
    • 10.1016/j.cell.2009.05.026 1:CAS:528:DC%2BD1MXhsVChs7nP 19665970
    • Y Zhao AJ Sfeir Y Zou CM Buseman TT Chow JW Shay WE Wright 2009 Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells Cell 138 463 475 10.1016/j.cell.2009.05.026 1:CAS:528: DC%2BD1MXhsVChs7nP 19665970
    • (2009) Cell , vol.138 , pp. 463-475
    • Zhao, Y.1    Sfeir, A.J.2    Zou, Y.3    Buseman, C.M.4    Chow, T.T.5    Shay, J.W.6    Wright, W.E.7
  • 47
    • 0036362266 scopus 로고    scopus 로고
    • Telomerase and differentiation in multicellular organisms: Turn it off, turn it on, and turn it off again
    • DOI 10.1046/j.1432-0436.2002.690412.x
    • NR Forsyth WE Wright JW Shay 2002 Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again Differentiation 69 188 197 10.1046/j.1432-0436.2002.690412.x 1:CAS:528:DC%2BD38Xhs1Witr4%3D 11841477 (Pubitemid 41701542)
    • (2002) Differentiation , vol.69 , Issue.4-5 , pp. 188-197
    • Forsyth, N.R.1    Wright, W.E.2    Shay, J.W.3
  • 48
    • 0034010312 scopus 로고    scopus 로고
    • Telomerase activity is down regulated via decreases in hTERT mRNA but not TEP1 mRNA or hTERC during the differentiation of leukemic cells
    • 1:CAS:528:DC%2BD3cXjsVertrw%3D 10810353
    • Y Koyanagi D Kobayashi T Yajima K Asanuma T Kimura T Sato T Kida A Yagihashi H Kameshima N Watanabe 2000 Telomerase activity is down regulated via decreases in hTERT mRNA but not TEP1 mRNA or hTERC during the differentiation of leukemic cells Anticancer Res 20 773 778 1:CAS:528:DC%2BD3cXjsVertrw%3D 10810353
    • (2000) Anticancer Res , vol.20 , pp. 773-778
    • Koyanagi, Y.1    Kobayashi, D.2    Yajima, T.3    Asanuma, K.4    Kimura, T.5    Sato, T.6    Kida, T.7    Yagihashi, A.8    Kameshima, H.9    Watanabe, N.10
  • 49
    • 38349150862 scopus 로고    scopus 로고
    • STAT3 and PKC differentially regulate telomerase activity during megakaryocytic differentiation of K562 cells
    • 1:CAS:528:DC%2BD2sXhtVaks7vI 17525530
    • M Nakatake Y Kakiuchi N Sasaki K Murakami-Murofushi O Yamada 2007 STAT3 and PKC differentially regulate telomerase activity during megakaryocytic differentiation of K562 cells Cell Cycle 6 1496 1501 1:CAS:528: DC%2BD2sXhtVaks7vI 17525530
    • (2007) Cell Cycle , vol.6 , pp. 1496-1501
    • Nakatake, M.1    Kakiuchi, Y.2    Sasaki, N.3    Murakami-Murofushi, K.4    Yamada, O.5
  • 50
    • 0035283896 scopus 로고    scopus 로고
    • Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development
    • DOI 10.1002/1097-0215(200002)9999:9999<::AID-IJC1103>3.0.CO;2-V
    • GA Ulaner JF Hu TH Vu LC Giudice AR Hoffman 2001 Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development Int J Cancer 91 644 649 10.1002/1097-0215(200002)9999:9999<::AID-IJC1103>3.0.CO;2-V 1:CAS:528:DC%2BD3MXht1ygsLk%3D 11267974 (Pubitemid 32115258)
    • (2001) International Journal of Cancer , vol.91 , Issue.5 , pp. 644-649
    • Ulaner, G.A.1    Hu, J.-F.2    Vu, T.H.3    Giudice, L.C.4    Hoffman, A.R.5
  • 51
    • 0029973653 scopus 로고    scopus 로고
    • Regulation of telomerase activity in immortal cell lines
    • 1:CAS:528:DyaK28XjtFCqsbo%3D 8649404
    • SE Holt WE Wright JW Shay 1996 Regulation of telomerase activity in immortal cell lines Mol Cell Biol 16 2932 2939 1:CAS:528:DyaK28XjtFCqsbo%3D 8649404
    • (1996) Mol Cell Biol , vol.16 , pp. 2932-2939
    • Holt, S.E.1    Wright, W.E.2    Shay, J.W.3
  • 52
    • 77249158324 scopus 로고    scopus 로고
    • Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT
    • 10.1016/j.canlet.2009.08.026 1:CAS:528:DC%2BC3cXis1emtL8%3D 19751963
    • JH Lee IK Chung 2010 Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT Cancer Lett 290 1 76 86 10.1016/j.canlet.2009.08.026 1:CAS:528:DC%2BC3cXis1emtL8%3D 19751963
    • (2010) Cancer Lett , vol.290 , Issue.1 , pp. 76-86
    • Lee, J.H.1    Chung, I.K.2
  • 53
    • 15644378537 scopus 로고    scopus 로고
    • The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer
    • DOI 10.1002/(SICI)1097-0142(19981015)83:8<1471::AID-CNCR1>3.0.CO;2- 6
    • WH Miller Jr 1998 The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer Cancer 83 1471 1482 10.1002/(SICI)1097-0142(19981015)83:8<1471::AID-CNCR1>3.0.CO;2-6 1:CAS:528:DyaK1cXntVejurY%3D 9781940 (Pubitemid 28465464)
    • (1998) Cancer , vol.83 , Issue.8 , pp. 1471-1482
    • Miller Jr., W.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.