Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway

Experimental Cell Research

Volumn 316, Issue 16, 2010, Pages 2644-2653

  White, Eric S ^a   Sagana, Rommel L ^a   Booth, Adam J ^a   Yan, Mei ^a   Cornett, Ashley M ^a   Bloomheart, Christopher A ^a   Tsui, Jessica L ^a   Wilke, Carol A ^a   Moore, Bethany B ^a   Ritzenthaler, Jeffrey D ^b   Roman, Jesse ^b   Muro, Andrés F ^c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b University of Louisville School of Medicine   (United States)

^c INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

Author keywords

Alternative splicing; Fibroblast; Fibronectin; Fibrosis; PTEN; Rapamycin

Indexed keywords

FIBRONECTIN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAPAMYCIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; LUCIFERASE; MESSENGER RNA; MTOR PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; PTEN PROTEIN, MOUSE; SIGNAL PEPTIDE; TARGET OF RAPAMYCIN KINASE; TRANSFORMING GROWTH FACTOR BETA;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION; GENE SILENCING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL MOTION; CYTOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

MAMMALIA;

ALTERNATIVE SPLICING; ANIMALS; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; FIBROBLASTS; FIBRONECTINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSFORMING GROWTH FACTOR BETA;

EID: 77955843468     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2010.06.028     Document Type: Article

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