메뉴 건너뛰기




Volumn 24, Issue 8, 2010, Pages 3066-3082

Fine mapping of AHI1 as a schizophrenia susceptibility gene: From association to evolutionary evidence

(22)  Torri, Federica a   Akelai, Anna g   Lupoli, Sara b   Sironi, Manuela c   Amann Zalcenstein, Daniela i   Fumagalli, Matteo c,d   Fiume, Chiara Dal a   Ben Asher, Edna h   Kanyas, Kyra g   Cagliani, Rachele c   Cozzi, Paolo f   Trombetti, Gabriele f   Lievers, Luisa Strik a   Salvi, Erika a   Orro, Alessandro e,f   Beckmann, Jacques S h   Lancet, Doron i   Kohn, Yoav g   Milanesi, Luciano f   Ebstein, Richard B j   more..


Author keywords

AHI1 association studies; Positive selection

Indexed keywords

ABELSON HELPER INTEGRATION SITE 1 PROTEIN; PROTEIN; PROTEIN MAP7; PROTEIN PDE7B; UNCLASSIFIED DRUG;

EID: 77955822772     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.09-152611     Document Type: Article
Times cited : (36)

References (124)
  • 1
    • 0012150654 scopus 로고    scopus 로고
    • Schizophrenia
    • (McGuffin, P., Owen, M.J., and Gottesman, I.I., eds) Oxford University Press, Oxford, UK
    • Owen, M. J., O'Donovan, M. C., and Gottesman, I. I. (2002) Schizophrenia. In Psychiatric Genetics & Genomics (McGuffin, P., Owen, M.J., and Gottesman, I.I., eds) pp. 247-266, Oxford University Press, Oxford, UK
    • (2002) Psychiatric Genetics & Genomics , pp. 247-266
    • Owen, M.J.1    O'Donovan, M.C.2    Gottesman, I.I.3
  • 2
    • 0028275174 scopus 로고
    • The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia?
    • McGuffin, P., Asherson, P., Owen, M., and Farmer, A. (1994) The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia? Br. J. Psych. 64, 593-599
    • (1994) Br. J. Psych. , vol.64 , pp. 593-599
    • McGuffin, P.1    Asherson, P.2    Owen, M.3    Farmer, A.4
  • 3
    • 0024670545 scopus 로고
    • A single dominant gene still cannot account for the transmission of schizophrenia
    • McGue, M., and Gottesman, I. I. (1989) A single dominant gene still cannot account for the transmission of schizophrenia. Arch. Gen. Psych. 46, 478-480
    • (1989) Arch. Gen. Psych. , vol.46 , pp. 478-480
    • McGue, M.1    Gottesman, I.I.2
  • 4
    • 0034535747 scopus 로고    scopus 로고
    • The genetic epidemiology of schizophrenia and of schizophrenia spectrum disorders
    • Lichtermann, D., Karbe, E., and Maier, W. (2000) The genetic epidemiology of schizophrenia and of schizophrenia spectrum disorders. Eur. Arch. Psychiatry Clin. Neurosci. 250, 304-310
    • (2000) Eur. Arch. Psychiatry Clin. Neurosci. , vol.250 , pp. 304-310
    • Lichtermann, D.1    Karbe, E.2    Maier, W.3
  • 5
    • 0036258079 scopus 로고    scopus 로고
    • Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia
    • Badner, J. A., and Gershon, E. S. (2002) Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol. Psychiatr. 7, 405-411
    • (2002) Mol. Psychiatr. , vol.7 , pp. 405-411
    • Badner, J.A.1    Gershon, E.S.2
  • 8
    • 3042838979 scopus 로고    scopus 로고
    • Genetics of schizophrenia-linkage findings: A review
    • Kohn, Y., and Lerer, B. (2002) Genetics of schizophrenia-linkage findings: a review. Israel J. Psychiatry Rel. Sci. 39, 240-251
    • (2002) Israel J. Psychiatry Rel. Sci. , vol.39 , pp. 240-251
    • Kohn, Y.1    Lerer, B.2
  • 9
    • 32844458681 scopus 로고    scopus 로고
    • Excitement and confusion on chromosome 6q: The challenges of neuropsychiatric genetics in microcosm
    • Kohn, Y., and Lerer, B. (2005) Excitement and confusion on chromosome 6q: the challenges of neuropsychiatric genetics in microcosm. Mol. Psychiatry 10, 1062-1073
    • (2005) Mol. Psychiatry , vol.10 , pp. 1062-1073
    • Kohn, Y.1    Lerer, B.2
  • 10
  • 18
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium
    • International Schizophrenia Consortium (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 6, 748-752
    • (2009) Nature , vol.6 , pp. 748-752
  • 19
    • 62849093626 scopus 로고    scopus 로고
    • Gene discovery through imaging genetics: Identification of two novel genes associated with schizophrenia
    • Potkin, S. G., Turner, J. A., Fallon, J. A., Lakatos, A., Keator, D. B., Guffanti, G., and Macciardi, F. (2009) Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia. Mol. Psychiatry 14, 416-428
    • (2009) Mol. Psychiatry , vol.14 , pp. 416-428
    • Potkin, S.G.1    Turner, J.A.2    Fallon, J.A.3    Lakatos, A.4    Keator, D.B.5    Guffanti, G.6    Macciardi, F.7
  • 22
    • 46249093584 scopus 로고    scopus 로고
    • Strong association of de novo copy number mutations with sporadic schizophrenia
    • Xu, B., Roos, J. L., Levy, S., Van Rensburg, E. J., Gogos, J. A., and Karayiorgou, M. (2008) Strong association of de novo copy number mutations with sporadic schizophrenia. Nat. Genet. 40, 880-885
    • (2008) Nat. Genet. , vol.40 , pp. 880-885
    • Xu, B.1    Roos, J.L.2    Levy, S.3    Van Rensburg, E.J.4    Gogos, J.A.5    Karayiorgou, M.6
  • 24
    • 51649107017 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications increase risk of schizophrenia
    • The International Schizophrenia Consortium
    • The International Schizophrenia Consortium (2008) Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 455, 237-241
    • (2008) Nature , vol.455 , pp. 237-241
  • 25
  • 26
    • 0037308528 scopus 로고    scopus 로고
    • Genes for schizophrenia? Recent findings and their pathophysiological implications
    • Harrison, P. J., and Owen, M. J. (2003) Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet 361, 417-419
    • (2003) Lancet , vol.361 , pp. 417-419
    • Harrison, P.J.1    Owen, M.J.2
  • 27
    • 0034018285 scopus 로고    scopus 로고
    • Linkage and associated studies of schizophrenia
    • Riley, B. P., and McGuffin, P. (2000) Linkage and associated studies of schizophrenia. Am. J. Med. Genet. 97, 23-44
    • (2000) Am. J. Med. Genet. , vol.97 , pp. 23-44
    • Riley, B.P.1    McGuffin, P.2
  • 48
    • 0003322588 scopus 로고
    • Dementia præcox, oder die Gruppe der Schizophrenien
    • (Aschaffenburg, G., ed), Deuticke, Leipzig, Germany
    • Bleuler, E. (1911) Dementia præcox, oder die Gruppe der Schizophrenien. In Handbuch der Psychiatrie (Aschaffenburg, G., ed), Deuticke, Leipzig, Germany
    • (1911) Handbuch der Psychiatrie
    • Bleuler, E.1
  • 49
    • 35848933704 scopus 로고    scopus 로고
    • Adaptive evolution of genes underlying schizophrenia
    • Crespi, B., Summers, K., and Dorus, S. (2007) Adaptive evolution of genes underlying schizophrenia. Proc. Biol. Sci. 274, 2801-2810
    • (2007) Proc. Biol. Sci. , vol.274 , pp. 2801-2810
    • Crespi, B.1    Summers, K.2    Dorus, S.3
  • 50
    • 39749136156 scopus 로고    scopus 로고
    • Natural selection has driven population differentiation in modern humans
    • Barreiro, L. B., Laval, G., Quach, H., Patin, E., and Quintana-Murci, L. (2008) Natural selection has driven population differentiation in modern humans. Nat. Genet. 40, 340-345
    • (2008) Nat. Genet. , vol.40 , pp. 340-345
    • Barreiro, L.B.1    Laval, G.2    Quach, H.3    Patin, E.4    Quintana-Murci, L.5
  • 53
    • 0033848442 scopus 로고    scopus 로고
    • Trends in the frequencies of consanguineous marriages in the Israeli Arab community
    • Jaber, L., Halpern, G. J., and Shohat, T. (2000) Trends in the frequencies of consanguineous marriages in the Israeli Arab community. Clin. Genet. 58, 106-110
    • (2000) Clin. Genet. , vol.58 , pp. 106-110
    • Jaber, L.1    Halpern, G.J.2    Shohat, T.3
  • 54
    • 0018082913 scopus 로고
    • Research diagnostic criteria: Rationale and reliability
    • Spitzer, R. L., Endicott, J. and Robins, E. (1978) Research diagnostic criteria: rationale and reliability. Arch. Gen. Psychiatry 35, 773-782
    • (1978) Arch. Gen. Psychiatry , vol.35 , pp. 773-782
    • Spitzer, R.L.1    Endicott, J.2    Robins, E.3
  • 55
    • 0017715978 scopus 로고
    • The family history method using diagnostic criteria. Reliability and validity
    • Andreasen, N. C., Endicott, J., Spitzer, R. L. and Winokur, G. (1977) The family history method using diagnostic criteria. Reliability and validity. Arch. Gen. Psychiatry 34, 1229-1235
    • (1977) Arch. Gen. Psychiatry , vol.34 , pp. 1229-1235
    • Andreasen, N.C.1    Endicott, J.2    Spitzer, R.L.3    Winokur, G.4
  • 59
    • 33847057776 scopus 로고    scopus 로고
    • Whole genome genotyping technologies on the BeadArray platform
    • Steemers, F. J., and Gunderson, K. L. (2007) Whole genome genotyping technologies on the BeadArray platform. Biotechnol. J. 2, 41-49
    • (2007) Biotechnol. J. , vol.2 , pp. 41-49
    • Steemers, F.J.1    Gunderson, K.L.2
  • 61
    • 0003752712 scopus 로고    scopus 로고
    • Sinauer Associates, Sunderland, MA, USA
    • Weir, B. S. (1996) Genetic Data Analysis II. Sinauer Associates, Sunderland, MA, USA
    • (1996) Genetic Data Analysis II
    • Weir, B.S.1
  • 62
    • 18944370235 scopus 로고    scopus 로고
    • Rational inferences about departures from Hardy-Weinberg equilibrium
    • Wittke-Thompson, J. K., Pluzhnikov, A., and Cox, N. J. (2005) Rational inferences about departures from Hardy-Weinberg equilibrium. Am. J. Hum. Genet. 76, 967-986
    • (2005) Am. J. Hum. Genet. , vol.76 , pp. 967-986
    • Wittke-Thompson, J.K.1    Pluzhnikov, A.2    Cox, N.J.3
  • 63
    • 17644379063 scopus 로고    scopus 로고
    • A note on exact tests of Hardy-Weinberg equilibrium
    • Wigginton, J. E., Cutler, D. J., and Abecasis, G. R. (2005) A note on exact tests of Hardy-Weinberg equilibrium. Am. J. Hum. Genet. 76, 887-893
    • (2005) Am. J. Hum. Genet. , vol.76 , pp. 887-893
    • Wigginton, J.E.1    Cutler, D.J.2    Abecasis, G.R.3
  • 64
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett, J. C., Fry, B., Maller, J., and Daly, M. J. (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 65
    • 0036844238 scopus 로고    scopus 로고
    • Distribution of recombination crossovers and the origin of haplotype blocks: The interplay of population history, recombination, and mutation
    • Wang, N., Akey. J. M., Zhang, K., Chakraborty, R., and Jin, L. (2002) Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation. Am. J. Hum. Genet. 71, 1227-1234
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 1227-1234
    • Wang, N.1    Akey, J.M.2    Zhang, K.3    Chakraborty, R.4    Jin, L.5
  • 66
    • 12244264435 scopus 로고    scopus 로고
    • Genetic power calculator: Design of linkage and association genetic mapping studies of complex traits
    • Purcell, S., Cherny, S. S., and Sham, P. C. (2003) Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19, 149-150
    • (2003) Bioinformatics , vol.19 , pp. 149-150
    • Purcell, S.1    Cherny, S.S.2    Sham, P.C.3
  • 68
    • 32044469601 scopus 로고    scopus 로고
    • PBAT: A comprehensive software package for genome-wide association analysis of complex family-based studies
    • Steen, K. V., and Lange, C. (2005) PBAT: A comprehensive software package for genome-wide association analysis of complex family-based studies. Hum. Genomics 2, 67-69
    • (2005) Hum. Genomics , vol.2 , pp. 67-69
    • Steen, K.V.1    Lange, C.2
  • 69
    • 0029075560 scopus 로고
    • The transmission/disequilibrium test: History, subdivision, and admixture
    • Ewens, W. J., and Spielman, R. S. (1995) The transmission/disequilibrium test: history, subdivision, and admixture. Am. J. Hum. Genet. 57, 455-464
    • (1995) Am. J. Hum. Genet. , vol.57 , pp. 455-464
    • Ewens, W.J.1    Spielman, R.S.2
  • 70
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y., and Hochberg, Y. (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. 57, 289-300
    • (1995) J. R. Stat. Soc. , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 71
  • 73
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel, N., and Haenszel, W. (1959) Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl. Cancer Inst. 22, 719-748
    • (1959) J. Natl. Cancer Inst. , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 74
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • Lohmueller, K. E., Pearce, C. L., Pike, M., Lander, E. S., and Hirschhorn, J. N. (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat. Genet. 33, 177-182
    • (2003) Nat. Genet. , vol.33 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 76
    • 0028905057 scopus 로고
    • Unrooted genealogical tree probabilities in the infinitely-many-sites model
    • Griffiths, R. C., and Tavare, S. (1995) Unrooted genealogical tree probabilities in the infinitely-many-sites model. Math. Biosci. 127, 77-98
    • (1995) Math. Biosci. , vol.127 , pp. 77-98
    • Griffiths, R.C.1    Tavare, S.2
  • 77
    • 0024313579 scopus 로고
    • Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
    • Tajima, F. (1989) Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123, 585-595
    • (1989) Genetics , vol.123 , pp. 585-595
    • Tajima, F.1
  • 78
    • 0027453041 scopus 로고
    • Statistical tests of neutrality of mutations
    • Fu, Y. X., and Li, W. H. (1993) Statistical tests of neutrality of mutations. Genetics 133, 693-709
    • (1993) Genetics , vol.133 , pp. 693-709
    • Fu, Y.X.1    Li, W.H.2
  • 79
    • 0017886236 scopus 로고
    • The homozygosity test of neutrality
    • Watterson, G. A. (1978) The homozygosity test of neutrality. Genetics 88, 405-417
    • (1978) Genetics , vol.88 , pp. 405-417
    • Watterson, G.A.1
  • 80
    • 0005814023 scopus 로고
    • Mathematical model for studying genetic variation in terms of restriction endonucleases
    • Nei, M., and Li, W. H. (1979) Mathematical model for studying genetic variation in terms of restriction endonucleases. Proc. Natl. Acad. Sci. U. S. A. 76, 5269-5273
    • (1979) Proc. Natl. Acad. Sci. U. S. A. , vol.76 , pp. 5269-5273
    • Nei, M.1    Li, W.H.2
  • 81
    • 0033911640 scopus 로고    scopus 로고
    • Hitchhiking under positive Darwinian selection
    • Fay, J. C., and Wu, C. I. (2000) Hitchhiking under positive Darwinian selection. Genetics 155, 1405-1413
    • (2000) Genetics , vol.155 , pp. 1405-1413
    • Fay, J.C.1    Wu, C.I.2
  • 82
    • 0344464730 scopus 로고    scopus 로고
    • Libsequence: A C++ class library for evolutionary genetic analysis
    • Thornton, K. (2003) Libsequence: a C++ class library for evolutionary genetic analysis. Bioinformatics 19, 2325-2327
    • (2003) Bioinformatics , vol.19 , pp. 2325-2327
    • Thornton, K.1
  • 83
  • 84
    • 85007110786 scopus 로고    scopus 로고
    • Arlequin ver. 3.0: An integrated software package for population genetics data analysis
    • Excoffier, L., Laval, G., and Schneider, S. (2005) Arlequin ver. 3.0: An integrated software package for population genetics data analysis. Evol. Bioinform. Online 1, 47-50
    • (2005) Evol. Bioinform. Online , vol.1 , pp. 47-50
    • Excoffier, L.1    Laval, G.2    Schneider, S.3
  • 85
    • 8544246487 scopus 로고    scopus 로고
    • The HKA test revisited: A maximum-likelihood-ratio test of the standard neutral model
    • Wright, S. I., and Charlesworth, B. (2004) The HKA test revisited: a maximum-likelihood-ratio test of the standard neutral model. Genetics 168, 1071-1076
    • (2004) Genetics , vol.168 , pp. 1071-1076
    • Wright, S.I.1    Charlesworth, B.2
  • 86
    • 59949095839 scopus 로고    scopus 로고
    • Widespread balancing selection and pathogen-driven selection at blood group antigen genes
    • Fumagalli, M., Cagliani, R., Pozzoli, U., Riva, S., and Comi, G. P. (2009) Widespread balancing selection and pathogen-driven selection at blood group antigen genes. Genome Res. 19, 199-212
    • (2009) Genome Res. , vol.19 , pp. 199-212
    • Fumagalli, M.1    Cagliani, R.2    Pozzoli, U.3    Riva, S.4    Comi, G.P.5
  • 87
    • 0032900678 scopus 로고    scopus 로고
    • Median-joining networks for inferring intraspecific phylogenies
    • Bandelt, H. J., Forster, P., and Röhl, A. (1999) Median-joining networks for inferring intraspecific phylogenies. Mol. Biol. Evol. 16, 37-48
    • (1999) Mol. Biol. Evol. , vol.16 , pp. 37-48
    • Bandelt, H.J.1    Forster, P.2    Röhl, A.3
  • 89
    • 38949155535 scopus 로고    scopus 로고
    • Inferring selection in partially sequenced regions
    • Jensen, J. D., Thornton, K. R., and Aquadro, C. F. (2008) Inferring selection in partially sequenced regions. Mol. Biol. Evol. 25, 438-446
    • (2008) Mol. Biol. Evol. , vol.25 , pp. 438-446
    • Jensen, J.D.1    Thornton, K.R.2    Aquadro, C.F.3
  • 90
    • 0016491430 scopus 로고
    • On the number of segregating sites in genetical models without recombination
    • Watterson, G. A. (1975) On the number of segregating sites in genetical models without recombination. Theor. Popul. Biol. 7, 256-276
    • (1975) Theor. Popul. Biol. , vol.7 , pp. 256-276
    • Watterson, G.A.1
  • 91
    • 0023339852 scopus 로고
    • A test of neutral molecular evolution based on nucleotide data
    • Hudson, R. R., Kreitman, M., and Aguade, M. (1987) A test of neutral molecular evolution based on nucleotide data. Genetics 116, 153-159
    • (1987) Genetics , vol.116 , pp. 153-159
    • Hudson, R.R.1    Kreitman, M.2    Aguade, M.3
  • 92
    • 35748956095 scopus 로고    scopus 로고
    • Brain imaging in schizophrenia
    • Hirayasu, Y. (2007) Brain imaging in schizophrenia. Neuropathology 27, 601-603
    • (2007) Neuropathology , vol.27 , pp. 601-603
    • Hirayasu, Y.1
  • 95
    • 44449096668 scopus 로고    scopus 로고
    • Absence of decussation of the superior cerebellar peduncles in patients with Joubert syndrome
    • Spampinato, M. V., Kraas, J., Maria, B. L., Walton, Z. J., and Rumboldt, Z. (2008) Absence of decussation of the superior cerebellar peduncles in patients with Joubert syndrome. Am. J. Med. Genet. 146A, 1389-1394
    • (2008) Am. J. Med. Genet. , vol.146 A , pp. 1389-1394
    • Spampinato, M.V.1    Kraas, J.2    Maria, B.L.3    Walton, Z.J.4    Rumboldt, Z.5
  • 96
    • 58149240676 scopus 로고    scopus 로고
    • Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies
    • Doering, J. E., Kane, K., Hsiao, Y. C., Yao, C., Shi, B., Slowik, A. D., Dhagat, B., Scott, D. D., Ault, J. G., Page-McCaw, P. S., and Ferland, R. J. (2008) Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies. J. Comp. Neurol. 511, 238-256
    • (2008) J. Comp. Neurol. , vol.511 , pp. 238-256
    • Doering, J.E.1    Kane, K.2    Hsiao, Y.C.3    Yao, C.4    Shi, B.5    Slowik, A.D.6    Dhagat, B.7    Scott, D.D.8    Ault, J.G.9    Page-McCaw, P.S.10    Ferland, R.J.11
  • 97
    • 0027534640 scopus 로고
    • An aromatase-associated cytoplasmic inclusion, the "stigmoid body," in the rat brain: II. Ultrastructure (with a review of its history and nomenclature)
    • Shinoda, K., Nagano, M., and Osawa, Y. (1993) An aromatase-associated cytoplasmic inclusion, the "stigmoid body," in the rat brain: II. Ultrastructure (with a review of its history and nomenclature). J. Comp. Neurol. 329, 1-19
    • (1993) J. Comp. Neurol. , vol.329 , pp. 1-19
    • Shinoda, K.1    Nagano, M.2    Osawa, Y.3
  • 99
    • 42749095376 scopus 로고    scopus 로고
    • Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
    • Lisman, J. E., Coyle, J. T., Green, R. W., Javitt, D. C., Benes, F. M., Heckers, S., and Grace, A, A. (2008) Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 31, 234-242
    • (2008) Trends Neurosci. , vol.31 , pp. 234-242
    • Lisman, J.E.1    Coyle, J.T.2    Green, R.W.3    Javitt, D.C.4    Benes, F.M.5    Heckers, S.6    Grace, A.A.7
  • 100
    • 48749109313 scopus 로고    scopus 로고
    • Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice
    • Sheng, G., Xu, X., Lin, Y. F., Wang, C. E., Rong, J., Cheng, D., Peng, J., Jiang, X., Li, S. H., and Li, X. J. (2008) Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice. J. Clin. Invest. 118, 2785-2795
    • (2008) J. Clin. Invest. , vol.118 , pp. 2785-2795
    • Sheng, G.1    Xu, X.2    Lin, Y.F.3    Wang, C.E.4    Rong, J.5    Cheng, D.6    Peng, J.7    Jiang, X.8    Li, S.H.9    Li, X.J.10
  • 103
    • 0042133327 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites
    • Gorsky, J. A., Zeiler, S. R., Tamowski, S., and Jones, K. R. (2003) Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites. J. Neurosci. 23, 6856-6865
    • (2003) J. Neurosci. , vol.23 , pp. 6856-6865
    • Gorsky, J.A.1    Zeiler, S.R.2    Tamowski, S.3    Jones, K.R.4
  • 104
    • 12144270390 scopus 로고    scopus 로고
    • Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia
    • Hashimoto, T., Bergen, S. E., Nguyen, Q. L., Xu, B., Monteggia, L. M., Pierri, J. N., Sun, Z., Sampson, A. R., and Lewis, D. A. (2005) Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. J. Neurosci. 25, 372-383
    • (2005) J. Neurosci. , vol.25 , pp. 372-383
    • Hashimoto, T.1    Bergen, S.E.2    Nguyen, Q.L.3    Xu, B.4    Monteggia, L.M.5    Pierri, J.N.6    Sun, Z.7    Sampson, A.R.8    Lewis, D.A.9
  • 105
    • 0036720981 scopus 로고    scopus 로고
    • Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations
    • Jiang, X., Hanna, Z., Kaouass, M., Girard, L., and Jolicoeur, P. (2002) Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations. J. Virol. 76, 9046-9059
    • (2002) J. Virol. , vol.76 , pp. 9046-9059
    • Jiang, X.1    Hanna, Z.2    Kaouass, M.3    Girard, L.4    Jolicoeur, P.5
  • 106
    • 0023215296 scopus 로고
    • Implications of normal brain development for the pathogenesis of schizophrenia
    • Weinberger, D. R. (1987) Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry 44, 660-669
    • (1987) Arch. Gen. Psychiatry , vol.44 , pp. 660-669
    • Weinberger, D.R.1
  • 107
    • 0034685655 scopus 로고    scopus 로고
    • Identification of human PDE7B, a cAMP-specific phosphodiesterase
    • Sasaki, T., Kotera, J., Yuasa, K., and Omori, K. (2000) Identification of human PDE7B, a cAMP-specific phosphodiesterase. Biochem. Biophys. Res. Commun. 271, 575-583
    • (2000) Biochem. Biophys. Res. Commun. , vol.271 , pp. 575-583
    • Sasaki, T.1    Kotera, J.2    Yuasa, K.3    Omori, K.4
  • 108
    • 0041695221 scopus 로고    scopus 로고
    • Alterations on phosphodiesterase type 7 and 8 isozyme mRNA expression in Alzheimer's disease brains examined by in situ hybridization
    • Pérez-Torres, S., Cortés, R., Tolnay, M., Probst, A., Palacios, J. M., and Mengod, G. (2003) Alterations on phosphodiesterase type 7 and 8 isozyme mRNA expression in Alzheimer's disease brains examined by in situ hybridization. Exp. Neurol. 182, 322-334
    • (2003) Exp. Neurol. , vol.182 , pp. 322-334
    • Pérez-Torres, S.1    Cortés, R.2    Tolnay, M.3    Probst, A.4    Palacios, J.M.5    Mengod, G.6
  • 109
    • 0027365430 scopus 로고
    • Identification and molecular characterization of E-MAP-115, a novel microtubule-associated protein predominantly expressed in epithelial cells
    • Masson, D., and Kreis, T. E. (1993) Identification and molecular characterization of E-MAP-115, a novel microtubule-associated protein predominantly expressed in epithelial cells. J. Cell Biol. 123, 357-371
    • (1993) J. Cell Biol. , vol.123 , pp. 357-371
    • Masson, D.1    Kreis, T.E.2
  • 110
    • 0037766786 scopus 로고    scopus 로고
    • DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: Regulation and loss of interaction with mutation
    • Morris, J. A., Kandpal, G., Ma, L., and Austin, C. P. (2003) DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. Hum. Mol. Genet. 12, 1591-1608
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1591-1608
    • Morris, J.A.1    Kandpal, G.2    Ma, L.3    Austin, C.P.4
  • 113
    • 44849141455 scopus 로고    scopus 로고
    • Evidence for impaired long-term potentiation in schizophrenia and its relationship to motor skill learning
    • Frantseva, M. V., Fitzgerald, P. B., Chen, R., Möller, B., Daigle, M., and Daskalakis, Z. J. (2008) Evidence for impaired long-term potentiation in schizophrenia and its relationship to motor skill learning. Cereb. Cortex 18, 990-996
    • (2008) Cereb. Cortex , vol.18 , pp. 990-996
    • Frantseva, M.V.1    Fitzgerald, P.B.2    Chen, R.3    Möller, B.4    Daigle, M.5    Daskalakis, Z.J.6
  • 114
    • 0001005077 scopus 로고
    • Schizophrenia as a genetic morphism
    • Huxley, J., Mayr, E., Osmond, H., and Hoffer, A. (1964) Schizophrenia as a genetic morphism. Nature 17, 220-221
    • (1964) Nature , vol.17 , pp. 220-221
    • Huxley, J.1    Mayr, E.2    Osmond, H.3    Hoffer, A.4
  • 115
    • 0031578929 scopus 로고    scopus 로고
    • Is schizophrenia the price that homo sapiens pays for language?
    • Crow, T. J. (1997) Is schizophrenia the price that homo sapiens pays for language? Schizophr. Res. 9, 127-141
    • (1997) Schizophr. Res. , vol.9 , pp. 127-141
    • Crow, T.J.1
  • 116
    • 33845516667 scopus 로고    scopus 로고
    • Resolving the paradox of common, harmful, heritable mental disorders: Which evolutionary genetic models work best?
    • Keller, M. C., and Miller, G. (2006) Resolving the paradox of common, harmful, heritable mental disorders: which evolutionary genetic models work best? Behav. Brain Sci. 29, 385-404
    • (2006) Behav. Brain Sci. , vol.29 , pp. 385-404
    • Keller, M.C.1    Miller, G.2
  • 117
    • 46249105511 scopus 로고    scopus 로고
    • "big bang" theory of the origin of psychosis and the faculty of language
    • Crow, T. J. (2008) The "big bang" theory of the origin of psychosis and the faculty of language. Schizophr. Res. 102, 31-52
    • (2008) Schizophr. Res. , vol.102 , pp. 31-52
    • Crow, T.J.1
  • 118
    • 0031744818 scopus 로고    scopus 로고
    • Schizophrenia: The illness that made us human
    • Horrobin, D. F. (1998) Schizophrenia: the illness that made us human. Med. Hypotheses 50, 269-288
    • (1998) Med. Hypotheses , vol.50 , pp. 269-288
    • Horrobin, D.F.1
  • 120
    • 34547681436 scopus 로고    scopus 로고
    • Comparisons of site- and haplotype-frequency methods for detecting positive selection
    • Zeng, K., Mano, S., Shi, S., and Wu, C. I. (2007) Comparisons of site- and haplotype-frequency methods for detecting positive selection. Mol. Biol. Evol. 24, 1562-1574
    • (2007) Mol. Biol. Evol. , vol.24 , pp. 1562-1574
    • Zeng, K.1    Mano, S.2    Shi, S.3    Wu, C.I.4
  • 121
    • 58449100012 scopus 로고    scopus 로고
    • An investigation of the statistical power of neutrality tests based on comparative and population genetic data
    • Zhai, W., Nielsen, R., and Slatkin, M. (2009) An investigation of the statistical power of neutrality tests based on comparative and population genetic data. Mol. Biol. Evol. 26, 273-283
    • (2009) Mol. Biol. Evol. , vol.26 , pp. 273-283
    • Zhai, W.1    Nielsen, R.2    Slatkin, M.3
  • 124
    • 0029854812 scopus 로고    scopus 로고
    • Biological and clinical significance of haptoglobin polymorphism in humans
    • Langlois, M. R., and Delanghe, J. R. (1996) Biological and clinical significance of haptoglobin polymorphism in humans. Clin. Chem. 42, 1589-1600
    • (1996) Clin. Chem. , vol.42 , pp. 1589-1600
    • Langlois, M.R.1    Delanghe, J.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.