Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer

Cancer Research

Volumn 70, Issue 16, 2010, Pages 6629-6638

  Metcalfe, Ciara ^a,d   Ibrahim, Ashraf E K ^a   Graeb, Michael ^a   De La Roche, Marc ^a   Schwarz Romond, Thomas ^a,e   Fiedler, Marc ^a   Winton, Douglas J ^b   Corfield, Anthony ^c   Bienz, Mariann ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b CANCER RESEARCH UK CAMBRIDGE RESEARCH INSTITUTE   (United Kingdom)

^c BRISTOL ROYAL INFIRMARY   (United Kingdom)

^d GENENTECH INC   (United States)

^e EMBO   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; AXIN; BETA CATENIN; DISHEVELLED 2; EVEROLIMUS; MAMMALIAN TARGET OF RAPAMYCIN; WNT PROTEIN; CARRIER PROTEIN; DISHEVELLED PROTEINS; EIF4EBP1 PROTEIN, MOUSE; MTOR PROTEIN, HUMAN; MTOR PROTEIN, MOUSE; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL SIZE; COLORECTAL ADENOMA; COLORECTAL CARCINOMA; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; GENE DELETION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMALL INTESTINE; TISSUE MICROARRAY; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CELL TRANSFORMATION; COLORECTAL TUMOR; GENETICS; INBREEDING; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PRECANCER; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; FEMALE; HUMANS; INBREEDING; INTESTINE, SMALL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PHOSPHOPROTEINS; PHOSPHORYLATION; PRECANCEROUS CONDITIONS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 77955735139     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-1616     Document Type: Article

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