Illumina-microarray analysis of mycophenolic acid-induced cell death in an insulin-producing cell line and primary rat islet cells: New insights into apoptotic pathways involved

Cellular Signalling

Volumn 22, Issue 11, 2010, Pages 1773-1782

  Park, Yun Jong ^a   Ahn, Hyung Joon ^a,b   Kim, Yu Seun ^a,c   Cho, Yuri ^a   Joo, Dong Jin ^a,c   Ju, Man Ki ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

Author keywords

Apoptosis; INS 1E; Islet cells; Mycophenolic acid; Rac1; RhoGDI

Indexed keywords

GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; MYCOPHENOLIC ACID; RAC1 PROTEIN; RHOGDI ALPHA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; GENE EXPRESSION; GENE OVEREXPRESSION; INSULINOMA; ISOLATED PANCREAS ISLET; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; GENE EXPRESSION REGULATION; GUANINE NUCLEOTIDE DISSOCIATION INHIBITORS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MYCOPHENOLIC ACID; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RAC1 GTP-BINDING PROTEIN; RATS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

RATTUS;

EID: 77955661974     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2010.07.005     Document Type: Article

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